公开(公告)号：US09352148B2

公开(公告)日：2016-05-31

申请号：US14192835

申请日：2014-02-27

Applicant: Greatbatch Ltd.

Inventor： Robert A. Stevenson ,  Richard L. Brendel

IPC: A61N1/375 ,  A61N1/08 ,  A61N1/37 ,  H01R103/00 ,  H01R24/58

CPC classification number: A61N1/08 ,  A61N1/086 ,  A61N1/3718 ,  A61N1/3752 ,  H01R24/58 ,  H01R2103/00 ,  H01R2201/12

Abstract: A header for an active implantable medical device includes a header block body and at least one active connector cavity configured to be attachable to an active lead. A first conductive leadwire has a first and second end, where the first end of the first conductive leadwire is electrically connected to the at least one active connector cavity and the second end of the first conductive leadwire is connectable to a hermetic terminal of the active implantable medical device. At least one abandoned connector cavity is located within the header block body configured to attachable to an abandoned lead. A second conductive leadwire has a first and second end, where the first end of the second conductive leadwire is electrically connected to the at least one abandoned connector cavity and the second end of the second conductive leadwire is connectable to the active implantable medical device housing.

Abstract translation: 用于有源可植入医疗装置的头部包括头部块主体和被配置为可附接到有源引线的至少一个有源连接器空腔。 第一导电引线具有第一和第二端，其中第一导电引线的第一端电连接到至少一个有源连接器腔，并且第一导电引线的第二端可连接到主动植入式的密封端 医疗装置。 至少一个废弃的连接器腔位于头部块主体内，其构造成可附接到废弃的引线。 第二导电引线具有第一和第二端，其中第二导电引线的第一端电连接到至少一个放弃的连接器腔，并且第二导电引线的第二端可连接到有源可植入医疗装置壳体。

公开(公告)号：US20160144188A1

公开(公告)日：2016-05-26

申请号：US15001327

申请日：2016-01-20

Applicant: Greatbatch Ltd.

Inventor： Joey Chen ,  Kerry Bradley ,  Leslie Halberg

IPC: A61N1/36

CPC classification number: A61N1/0551 ,  A61B5/064 ,  A61B8/0841 ,  A61N1/05 ,  A61N1/0553 ,  A61N1/36017 ,  A61N1/36021 ,  A61N1/36071 ,  A61N1/36125 ,  A61N1/36139 ,  A61N1/36146 ,  A61N1/36153 ,  A61N1/37223 ,  A61N1/37235 ,  A61N1/37252 ,  A61N1/3752 ,  A61N1/3787

Abstract: A patient is detected to be in a first posture state. In response to the patient being detected to be in the first posture state, a first electrical stimulation therapy is applied to a body region of the patient by a pulse generator implanted in the patient. The patient is detected to be in a second posture state. In response to the patient being detected to be in the second posture state that is different from the first posture state, a second electrical stimulation therapy is applied to the body region of the patient by the pulse generator. The second electrical stimulation therapy is different from the first electrical stimulation therapy.

Abstract translation: 检测到患者处于第一姿势状态。 响应于检测到患者处于第一姿势状态，通过植入患者体内的脉冲发生器对患者的身体区域施加第一电刺激治疗。 检测到患者处于第二姿势状态。 响应于检测到患者处于与第一姿势状态不同的第二姿势状态，通过脉冲发生器对患者的身体区域施加第二电刺激治疗。 第二次电刺激治疗与第一次电刺激治疗不同。

公开(公告)号：US09314178B2

公开(公告)日：2016-04-19

申请号：US14209035

申请日：2014-03-13

Applicant: Greatbatch Ltd.

Inventor： Rodolphe Katra ,  Niranjan Chakravarthy

IPC: A61B5/04 ,  A61B5/042 ,  A61B5/0464 ,  A61B5/024 ,  A61B5/046

CPC classification number: A61B5/04012 ,  A61B5/024 ,  A61B5/0422 ,  A61B5/046 ,  A61B5/0464 ,  A61B2560/0209

Abstract: A medical device includes a housing configured for implantation within a body of a patient, and detection circuitry disposed in the housing and coupled to an electrode arrangement. The detection circuitry is configured to sense cardiac signals from the patient. A processor is coupled to the detection circuitry. The processor is configured to compare the cardiac signals to an initial detection threshold, automatically generate an additional detection threshold in response to a predetermined number of the cardiac signals meeting or exceeding the initial detection threshold or a previously generated detection threshold, count each occurrence of a cardiac signal meeting or exceeding each of the respective detection thresholds, and record cardiac signal data only for a cardiac signal that meets or exceeds the highest of the detection thresholds.

Abstract translation: 医疗装置包括构造成用于植入患者体内的壳体，以及设置在壳体中并耦合到电极装置的检测电路。 检测电路被配置为感测来自患者的心脏信号。 处理器耦合到检测电路。 处理器被配置为将心脏信号与初始检测阈值进行比较，响应于满足或超过初始检测阈值或先前产生的检测阈值的预定数量的心脏信号自动产生附加检测阈值， 心跳信号满足或超过每个相应的检测阈值，并且仅记录满足或超过检测阈值的最高的心脏信号的心脏信号数据。

公开(公告)号：US09312075B1

公开(公告)日：2016-04-12

申请号：US14479689

申请日：2014-09-08

Applicant: Greatbatch Ltd.

Inventor： Yanming Liu ,  Barry C. Muffoletto ,  Jason T. Hahl

IPC: H01G9/00 ,  B22F5/00 ,  H01G9/052 ,  H01G9/145 ,  H01G9/10 ,  H01G9/02 ,  B22F3/24

CPC classification number: H01G9/0525 ,  B22F1/0096 ,  B22F3/24 ,  B22F5/00 ,  B22F2998/10 ,  B22F2999/00 ,  H01G9/0032 ,  H01G9/02 ,  H01G9/052 ,  H01G9/145 ,  B22F9/04 ,  B22F3/02 ,  B22F3/10 ,  B22F2003/242 ,  B22F2201/11 ,  B22F1/0014

Abstract: Tantalum powders produced using a tantalum fiber precursor are described. The tantalum fiber precursor is chopped or cut into short lengths having a uniform fiber thickness and favorable aspect ratio. The chopped fibers are formed into a primary powder having a controlled size and shape, narrow/tight particle size distribution, and low impurity level. The primary powder is then agglomerated into an agglomerated powder displaying suitable flowability and pressability such that pellets with good structural integrity and unifrom pellet porosity are manufacturable. The pellet is sintered and anodized to a desired formation voltage. The thusly created capacitor anode has a dual morphology or dual porosity provided by a primary porosity of the individual tantalum fibers making up the primary powder and a larger secondary porosity formed between the primary powders agglomerated into the agglomerated powder.

Abstract translation: 描述了使用钽纤维前体制备的钽粉末。 将钽纤维前体切碎或切割成具有均匀的纤维厚度和有利的纵横比的短长度。 短切纤维形成具有受控尺寸和形状，窄/紧密粒度分布和低杂质水平的初级粉末。 然后将初级粉末凝聚成显示合适的流动性和压制性的附聚粉末，使得具有良好结构完整性和均匀颗粒孔隙度的颗粒是可制造的。 将颗粒烧结并阳极氧化至所需的地层电压。 由此产生的电容器阳极具有由构成初级粉末的各个钽纤维的初级孔隙率提供的双重形态或双重孔隙，并且在附聚到聚集的粉末中的初级粉末之间形成较大的次生孔隙。

公开(公告)号：US20160066850A1

公开(公告)日：2016-03-10

申请号：US14942235

申请日：2015-11-16

Applicant: Greatbatch Ltd.

Inventor： Brian P. Brockway ,  Perry A. Mills

IPC: A61B5/00 ,  A61B5/07 ,  A61B5/042

CPC classification number: A61B5/686 ,  A61B5/0031 ,  A61B5/042 ,  A61B5/0422 ,  A61B5/076 ,  A61B5/7232 ,  A61B2560/0219 ,  A61B2560/063 ,  A61B2560/066 ,  A61B2562/164 ,  A61B2562/18 ,  A61N1/0504 ,  A61N1/37229 ,  A61N1/375 ,  A61N1/3756 ,  A61N1/3787

Abstract: An implantable monitoring device includes a flexible lead body that includes at least one sensing element. The device also includes a rigid main body connected to the flexible lead body at an attachment point. The rigid main body is generally centered about a longitudinal axis defined by the flexible lead body when the lead body is unflexed. The device further includes a measurement circuit, which is housed within the rigid main body and electrically coupled to the at least one sensing element of the flexible lead body and at least another sensing element on an outside surface of the rigid main body. The measurement circuit is configured to measure a potential difference between the at least one sensing element of the flexible lead body and the at least another sensing element of the main body.

Abstract translation: 可植入监测装置包括一个包括至少一个传感元件的柔性引线体。 该装置还包括在附接点处连接到柔性引线主体的刚性主体。 当铅体未折叠时，刚性主体通常由柔性引线体限定的纵向轴线对准。 该装置还包括测量电路，该测量电路容纳在刚性主体内并且电耦合到柔性引线本体的至少一个感测元件以及刚性主体的外表面上的至少另一个感测元件。 测量电路被配置为测量柔性引线体的至少一个感测元件与主体的至少另一感测元件之间的电位差。

公开(公告)号：US09259577B2

公开(公告)日：2016-02-16

申请号：US13973316

申请日：2013-08-22

Applicant: Greatbatch Ltd.

Inventor： Norbert Kaula ,  Scott Drees ,  Yohannes Iyassu ,  Seth Kaufman

IPC: A61N1/36 ,  A61N1/372 ,  G06F19/00

CPC classification number: A61N1/36185 ,  A61N1/0551 ,  A61N1/36071 ,  A61N1/36132 ,  A61N1/37241 ,  A61N1/37247 ,  G16H40/63

Abstract: The present disclosure involves a method of determining electrode configuration and positioning for neurostimulation. A virtual representation of an implant lead is provided. The implant lead is configured to deliver electrical stimulation to a patient via one or more of a plurality of electrodes located on the implant lead. A predefined electrode activation pattern is provided. The electrode activation pattern identifies a plurality of subsets of the electrodes that can be activated one subset at a time. The electrodes in each subset are programmed with their respective electrical stimulation parameters. The subsets of the electrodes are activated one subset at a time. Each activated subset of electrodes delivers electrical stimulation to a different region of a spine of the patient.

Abstract translation: 本公开涉及一种确定电极配置和神经刺激定位的方法。 提供植入物引线的虚拟表示。 植入物引线经配置以通过位于植入物引线上的多个电极中的一个或多个向患者传递电刺激。 提供预定的电极激活模式。 电极激活模式识别可以一次激活一个子集的电极的多个子集。 每个子集中的电极用各自的电刺激参数进行编程。 电极的子集一次被激活一个子集。 每个激活的电极子集将电刺激递送到患者脊柱的不同区域。

公开(公告)号：US20150202430A1

公开(公告)日：2015-07-23

申请号：US14161756

申请日：2014-01-23

Applicant: Greatbatch Ltd.

Inventor： James Finley ,  John M. Swoyer

IPC: A61N1/05 ,  D04C1/06 ,  B29C70/24 ,  H01R43/00

CPC classification number: A61N1/05 ,  A61N1/0551 ,  A61N1/0558 ,  A61N1/3605 ,  B29C70/24 ,  D04C1/06 ,  D10B2509/00 ,  Y10T29/49169 ,  Y10T29/49801

Abstract: In some examples, a method of making a therapy delivery element configured for at least partial insertion in a living body includes braiding a plurality of fibers to form an elongated braided structure with a lumen. At least one reinforcing structure is weaved into the fibers of the braided structure. A portion of the reinforcing structure is extended from the braided structure to form at least one fixation structure. At least one of the braided structure or the reinforcing structure can be attached to at least one of an electrode assembly or a connector assembly.

Abstract translation: 在一些实例中，制造用于至少部分插入生物体中的治疗递送元件的方法包括编织多根纤维以形成具有内腔的细长编织结构。 将至少一个加强结构编织到编织结构的纤维中。 加强结构的一部分从编织结构延伸以形成至少一个固定结构。 编织结构或加强结构中的至少一个可以附接到电极组件或连接器组件中的至少一个。

公开(公告)号：US20150196379A1

公开(公告)日：2015-07-16

申请号：US14595583

申请日：2015-01-13

Applicant: Greatbatch Ltd.

Inventor： Carole L. Norris ,  Elliot Bridgeman

IPC: A61F2/00

CPC classification number: A61M25/002 ,  A61B50/20 ,  A61B50/33

Abstract: In various examples, an apparatus includes a tray including a channel configured to hold a therapy delivery element at least partially within the channel. A retention clip is sized and shaped to fit within a portion of the channel. The retention clip is configured to releasably retain the therapy delivery element within the retention clip.

Abstract translation: 在各种示例中，一种装置包括托盘，托盘包括配置成至少部分地保持在通道内的治疗递送元件的通道。 保持夹的尺寸和形状适合于通道的一部分内。 保持夹构造成将治疗递送元件可释放地保持在保持夹内。

公开(公告)号：US09071221B1

公开(公告)日：2015-06-30

申请号：US14669041

申请日：2015-03-26

Applicant: GREATBATCH LTD.

Inventor： Robert A. Stevenson ,  Robert Shawn Johnson ,  Kishore Kumar Kondabatni ,  Joseph E. Spaulding ,  Dominick J. Frustaci ,  Warren S. Dabney ,  Holly Noelle Moschiano

IPC: A61N1/36 ,  H03H7/01 ,  A61N1/08

CPC classification number: H03H7/0123 ,  A61B5/042 ,  A61B5/055 ,  A61B18/1492 ,  A61B2018/00839 ,  A61B2090/374 ,  A61B2562/182 ,  A61B2562/222 ,  A61B2562/227 ,  A61N1/05 ,  A61N1/08 ,  A61N1/086 ,  A61N1/3718 ,  H03H1/0007 ,  H03H2001/0021 ,  H03H2007/013

Abstract: A composite RF current attenuator for a medical lead includes a conductor having a distal electrode contactable to biological cells, a bandstop filter in series with the lead conductor for attenuating RF currents flow through the lead conductor at a selected center frequency or across a range of frequencies about the center frequency, and a lowpass filter in series with the bandstop filter and forming a portion of the lead conductor. The bandstop filter has a capacitance in parallel with a first inductance. In a preferred form, the lowpass filter includes a second inductance in series with the bandstop filter, wherein the values of capacitance and inductances for the composite RF current attenuator are selected such that it attenuates MRI-induced RF current flow in an MRI environment.

Abstract translation: 用于医用引线的复合RF电流衰减器包括具有可与生物细胞接触的远端电极的导体，与引线导体串联的带阻滤波器，用于衰减RF电流以选定的中心频率或跨频率范围流过引线导体 关于中心频率，以及与带阻滤波器串联的低通滤波器，并形成引线导体的一部分。 带阻滤波器具有与第一电感并联的电容。 在优选形式中，低通滤波器包括与带阻滤波器串联的第二电感，其中复合RF电流衰减器的电容值和电感值被选择为使其在MRI环境中衰减MRI诱导的RF电流。

公开(公告)号：US09031670B2

公开(公告)日：2015-05-12

申请号：US14264080

申请日：2014-04-29

Applicant: Greatbatch Ltd.

Inventor： Warren S. Dabney ,  Robert Shawn Johnson ,  Holly Noelle Moschiano ,  Robert A. Stevenson ,  Henry R. Halperin ,  Albert C. Lardo ,  Kishore Kumar Kondabatni

IPC: A61N1/00 ,  A61N1/08 ,  A61N1/05

CPC classification number: A61N1/08 ,  A61N1/05 ,  A61N1/086 ,  H03H1/0007 ,  H03H7/1758 ,  H03H7/1766 ,  H03H2001/0042 ,  H03H2001/005 ,  H03H2007/013

Abstract: A shielded component or network for an active medical device (AMD) implantable lead includes an implantable lead having a length extending from a proximal end to a distal end, all external of an AMD housing, a passive component or network disposed somewhere along the length of the implantable lead, the passive component or network including at least one inductive component having a first inductive value, and an electromagnetic shield substantially surrounding the inductive component or the passive network. The first inductive value of the inductive component is adjusted to account for a shift in its inductance to a second inductive value when shielded.

Abstract translation: 用于有源医疗器件（AMD）可植入引线的屏蔽部件或网络包括具有从近端延伸到远端的长度的可植入引线，AMD壳体的外部，被动部件或网络，其设置在沿着 所述可植入引线，所述无源部件或网络包括至少一个具有第一感应值的感应部件和基本上围绕所述电感部件或所述无源网络的电磁屏蔽。 调整电感分量的第一感应值，以便在屏蔽时考虑其电感的移动到第二感应值。