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公开(公告)号：US06200982B1
公开(公告)日：2001-03-13
申请号：US09423178
申请日：2000-02-11
Applicant: Ian James Collins , Stephen Robert Fletcher , Timothy Harrison , Paul David Leeson , Christopher Richard Moyes , Alan John Nadin , Michael Rowley , Timothy Jason Sparey , Martin Richard Teall
Inventor： Ian James Collins , Stephen Robert Fletcher , Timothy Harrison , Paul David Leeson , Christopher Richard Moyes , Alan John Nadin , Michael Rowley , Timothy Jason Sparey , Martin Richard Teall
IPC: A61K31435
CPC classification number: C07D213/64 , C07D401/04 , C07D401/14 , C07D409/14 , C07D413/14 , C07D417/04 , C07D417/14
Abstract: Substituted 1H-Pyridinyl-2-ones are useful as GABAA-Alpha 2/3 ligands.
Abstract translation: 取代的1H-吡啶基-2-酮可用作GABAA-α2/3配体
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公开(公告)号：US5827464A
公开(公告)日：1998-10-27
申请号：US475122
申请日：1995-06-07
Applicant: David George Bennie , Robert James Collins , Hans Rudolf Edward Frankfort , Stephen Buckner Johnson , Benjamin Hughes Knox , Joe Forrest London, Jr. , Elmer Edwin Most, Jr. , Girish Anant Pai
Inventor： David George Bennie , Robert James Collins , Hans Rudolf Edward Frankfort , Stephen Buckner Johnson , Benjamin Hughes Knox , Joe Forrest London, Jr. , Elmer Edwin Most, Jr. , Girish Anant Pai
IPC: A63F1/04 , A63F3/00 , A63F9/04 , D01D5/08 , D01D5/24 , D01F6/62 , D02G1/18 , D02G3/02 , D02J1/22 , B29C47/88
CPC classification number: A63F3/00075 , D01D5/082 , D01D5/24 , D01F6/62 , D02G1/18 , D02G3/02 , D02J1/22 , A63F1/04 , A63F9/04 , Y10S57/908
Abstract: A direct melt spinning process for providing high filament count fine filament polyester yarns having excellent mechanical quality and along-end uniformity and unitary interlace by spinning all the filaments of such high filament count yarn from a single spinneret. Such yarns may be used as direct-use yarns and as draw-feed yarns for preparing drawn flat yarns and draw-textured yarns.
Abstract translation: 直接熔融纺丝工艺，通过从单个喷丝头中纺出这种高丝数纱线的所有长丝，提供高丝数细丝聚酯纱线，其具有优异的机械质量和端部均匀性和单一交织。 这种纱线可以用作直接使用纱线和用作制备拉伸扁丝和拉伸变形纱线的拉伸喂纱纱线。
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公开(公告)号：US1750190A
公开(公告)日：1930-03-11
申请号：US32581728
申请日：1928-12-13
Applicant: JAMES COLLINS , FRANK J BINSACK , ELMER W O BRIEN
Inventor： PAVELSKY THOMAS R
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84.发明授权Haze reduction for blends of aromatic-aliphatic polyesters with aliphatic polyesters and antimicrobial additives 有权芳香族 - 脂族聚酯与脂肪族聚酯和抗微生物添加剂的共混物的雾度降低公开(公告)号：US08633262B2
公开(公告)日：2014-01-21
申请号：US13097696
申请日：2011-04-29
Applicant: Michael Eugene Donelson , James Collins Maine , Gary Stuart Hawkins , Jeff Scott Howell
IPC: C08K3/10
CPC classification number: C08L67/02 , C08G63/12 , C08K3/015 , C08K3/10 , C08K3/22 , C08K3/24 , C08K3/32 , C08L75/16 , C08L2205/02 , C08L2666/18 , C08L2666/54
Abstract: This invention relates to a polymer blend comprising: (A) about 1% by weight to about 99% by weight of at least one polymer (A) comprising terephthalic acid residues, 2,2,4,4-tetramethyl-1,3-cyclobutanediol residues; and 1,4-cyclohexanedimethanol residues; (B) about 1% by weight to about 99% by weight of at least one polymer (B) comprising 1,4-cyclohexanedicarboxylic acid residues and 1,4-cyclohexanedimethanol residues, and (C) about 0.01% by weight to about 20% by weight of at least one antimicrobial agent; said weight percentages being based on the total weight of the polymer blend.
Abstract translation: 本发明涉及一种聚合物共混物，其包含：（A）约1重量％至约99重量％的至少一种包含对苯二甲酸残基的聚合物（A），2,2,4,4-四甲基-1,3- 环丁二醇残基; 和1,4-环己烷二甲醇残基; （B）约1重量％至约99重量％的至少一种包含1,4-环己烷二羧酸残基和1,4-环己烷二甲醇残基的聚合物（B），和（C）约0.01重量％至约20重量％ 重量％的至少一种抗微生物剂; 所述重量百分比基于聚合物共混物的总重量。
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公开(公告)号：US20120320313A1
公开(公告)日：2012-12-20
申请号：US13160785
申请日：2011-06-15
Applicant: Michael Eugene Donelson , James Collins Maine , Bin Wang , Marcus David Shelby
Inventor： Michael Eugene Donelson , James Collins Maine , Bin Wang , Marcus David Shelby
IPC: G02F1/1335 , B29D11/00 , G02B5/30
CPC classification number: C08J5/18 , B29C39/02 , B29C71/02 , B29D11/00788 , B29K2001/12 , B29K2105/0038 , B29L2011/00 , C08J2301/12 , C08K5/103 , G02B1/105 , G02B1/14 , G02B5/3025 , G02F1/133528 , G02F1/13363 , G02F2413/01 , Y10T428/105
Abstract: The present invention relates to films made from cellulose triacetate having low hydroxyl content and certain plasticizers. These films can exhibit low or zero optical retardation values, making them particularly suitable for use in optical applications, such as in liquid crystal displays (LCD) as protective and compensator films.
Abstract translation: 本发明涉及由羟基含量低的纤维素三乙酸酯和某些增塑剂制成的薄膜。 这些膜可以表现出低或零的光学延迟值，使得它们特别适用于光学应用，例如液晶显示器（LCD）作为保护膜和补偿膜。
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Patent Agency Ranking
86.发明申请Haze Reduction for Blends of Aromatic-Aliphatic Polyesters and Antimicrobial Additives 失效芳香族 - 脂肪族聚酯和抗微生物添加剂的共混物的雾度降低公开(公告)号：US20120184641A1
公开(公告)日：2012-07-19
申请号：US13097701
申请日：2011-04-29
Applicant: Michael Eugene Donelson , James Collins Maine , Gary Stuart Hawkins , Jeff Scott Howell
CPC classification number: C08L67/02 , C08G63/12 , C08K3/015 , C08K3/10 , C08K3/22 , C08K3/24 , C08K3/32 , C08L75/16 , C08L2205/02 , C08L2666/18 , C08L2666/54
Abstract: This invention relates to a blend comprising:(A) about 80% by weight to about 99.99% by weight of at least one polyester comprising terephthalic acid residues, 2,2,4,4-tetramethyl-1,3-cyclobutanediol residues; and 1,4-cyclohexanedimethanol residues; and (B) about 0.01% by weight to about 20% by weight of at least one antimicrobial agent; said weight percentages being based on the total weight of the blend.
Abstract translation: 本发明涉及一种共混物，其包含：（A）约80重量％至约99.99重量％的至少一种包含对苯二甲酸残基的聚酯，2,2,4,4-四甲基-1,3-环丁二醇残基; 和1,4-环己烷二甲醇残基; 和（B）约0.01重量％至约20重量％的至少一种抗微生物剂; 所述重量百分比基于共混物的总重量。
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87.发明授权Method and apparatus for constructing a forwarding database for a data communications network 有权用于构建数据通信网络的转发数据库的方法和装置公开(公告)号：US07969995B2
公开(公告)日：2011-06-28
申请号：US11211105
申请日：2005-08-23
Applicant: Matthew James Collins , Neil Alasdair James Jarvis
Inventor： Matthew James Collins , Neil Alasdair James Jarvis
IPC: H04L12/28
Abstract: A method of constructing a forwarding database for a data communications network comprising a plurality of network components and supporting at least first and second topologies having one or more common network components is described. The forwarding database includes at least first and second database structures having records including forwarding information for data destined for related network components in the respective topologies. Each database structure has a plurality of elements including a pointer to one of a succeeding element or a record including said forwarding information. The method comprises the step, performed at a constructing network component of identifying a network component common to the first and second topologies for which a record exists in the second database structure. The method further comprises the step of including a pointer from the related element in the first database structure to a corresponding element or record in the second database structure.
Abstract translation: 描述了构建包括多个网络组件并且支持具有一个或多个公共网络组件的至少第一和第二拓扑的数据通信网络的转发数据库的方法。 转发数据库至少包括具有记录的至少第一和第二数据库结构，包括用于相应拓扑中的相关网络组件的数据的转发信息。 每个数据库结构具有多个元素，包括指向后续元素之一的指针或包括所述转发信息的记录。 该方法包括以下步骤：在构建网络组件处执行识别在第二数据库结构中存在记录的第一和第二拓扑共同的网络组件。 该方法还包括将来自第一数据库结构中的相关元素的指针包括到第二数据库结构中的相应元素或记录的步骤。
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公开(公告)号：US07810570B2
公开(公告)日：2010-10-12
申请号：US11552889
申请日：2006-10-25
Applicant: James Collins , Mark T. Andreychuk
Inventor： James Collins , Mark T. Andreychuk
IPC: E21B43/26
CPC classification number: E21B43/26 , E21B43/006
Abstract: A shock tool is adapted to a bottom hole tool assembly for isolating a zone in a subterranean formation accessed by a wellbore. Fracturing fluid such as nitrogen is accumulated at fracturing pressures uphole of the shock tool for subsequent and rapid release to the formation. The tool assembly can be suspended from a conveyance string in which fluid is accumulated for shock release through a valve of the shock tool and through an injection tool to the zone isolated by the injection tool. After a first zone is shocked, the tool assembly can be moved to a new zone, or multiple shocks can be applied cyclically at the selected zone.
Abstract translation: 冲击工具适用于用于隔离由井筒访问的地下地层中的区域的井底工具组件。 压裂液如氮气在冲击工具的压裂压力下积聚，以便随后快速释放到地层。 工具组件可以从其中积聚流体的传送绳悬挂，以通过冲击工具的阀进行冲击释放，并通过注射工具到由注射工具隔离的区域。 在第一个区域被震动之后，工具组件可以移动到新的区域，或者可以在所选择的区域周期地施加多个冲击。
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89.发明申请公开(公告)号：US20090264342A1
公开(公告)日：2009-10-22
申请号：US12279237
申请日：2007-02-13
Applicant: Guillaume Cottarel , Jamey Wierzbowski , Kollol Pal , Michael Kohanski , Daniel Dwyer , James Collins , Michael Almstetter , Michael Thormann , Andreas Treml
Inventor： Guillaume Cottarel , Jamey Wierzbowski , Kollol Pal , Michael Kohanski , Daniel Dwyer , James Collins , Michael Almstetter , Michael Thormann , Andreas Treml
IPC: A61K38/00 , C12Q1/68 , C12N5/02 , A61K31/70 , A61K31/435 , A61K31/352
CPC classification number: A61K45/06 , A61K38/12 , C12Q1/18 , G01N33/5023 , A61K2300/00
Abstract: The present invention provides methods for identifying target genes whose partial or complete functional inactivation potentiates the activity of an antibiotic agent, e.g., a quinolone antibiotic. The invention further provides methods for identifying agents that modulate expression of target genes or that modulate activity of expression products of target genes. Agents identified according to various methods of the invention potentiate the activity of antibiotics such as quinolones, aminoglycosides, peptide antibiotics and β-lactams. Also provided are agents that suppress and/or retard resistance to antibiotics. The inventive methods provide potentiating agents and compositions comprising potentiating agents and antibiotics. Such agents and compositions can be used for inhibiting growth or survival of a microbial cell or of treating a subject suffering from or susceptible to a microbial infection.
Abstract translation: 本发明提供用于鉴定其部分或完全功能失活增强抗生素试剂例如喹诺酮抗生素活性的靶基因的方法。 本发明还提供用于鉴定调节靶基因表达或调节靶基因表达产物的活性的试剂的方法。 根据本发明各种方法鉴定的药剂增强了抗生素如喹诺酮类，氨基糖苷类，肽类抗生素和β-内酰胺类的活性。 还提供了抑制和/或延缓抗生素抗性的药剂。 本发明的方法提供增效剂和包含增效剂和抗生素的组合物。 这些药剂和组合物可用于抑制微生物细胞的生长或存活或治疗患有或易受微生物感染的受试者。
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公开(公告)号：US07365196B2
公开(公告)日：2008-04-29
申请号：US10239233
申请日：2001-03-15
Applicant: Patrice Charles Belanger , Ian James Collins , Joanne Claire Hannam , Timothy Harrison , Stephen John Lewis , Andrew Madin , Edward Giles McIver , Alan John Nadin , Joseph George Neduvelil , Mark Steven Shearman , Adrian Leonard Smith , Timothy Jason Sparey , Graeme Irvine Stevenson , Martin Richard Teall
Inventor： Patrice Charles Belanger , Ian James Collins , Joanne Claire Hannam , Timothy Harrison , Stephen John Lewis , Andrew Madin , Edward Giles McIver , Alan John Nadin , Joseph George Neduvelil , Mark Steven Shearman , Adrian Leonard Smith , Timothy Jason Sparey , Graeme Irvine Stevenson , Martin Richard Teall
IPC: C07D413/14 , C07D413/12 , C07D213/71 , C07D213/52 , C07D333/34 , C07D409/14 , C07D409/12 , C07D249/12 , C07D233/84 , C07D207/48 , C07D277/16 , C07D307/64 , A61P25/28
CPC classification number: C07D213/30 , A61K31/18 , A61K31/40 , C07C311/07 , C07C311/09 , C07C311/11 , C07C311/14 , C07C311/20 , C07C311/24 , C07C323/67 , C07C2601/08 , C07C2601/14 , C07C2602/44 , C07C2602/46 , C07C2603/72 , C07C2603/78 , C07D207/36 , C07D211/14 , C07D211/18 , C07D213/71 , C07D213/81 , C07D215/12 , C07D223/32 , C07D231/12 , C07D233/56 , C07D249/08 , C07D271/107 , C07D277/36 , C07D285/14 , C07D285/16 , C07D295/088 , C07D295/135 , C07D295/26 , C07D307/64 , C07D307/81 , C07D319/18 , C07D333/34 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/04 , C07D417/06 , C07D417/12 , C07D417/14 , C07D487/04 , C07D487/08 , C07D491/08 , C07D491/10 , C07D513/10
Abstract: A class of compounds is disclosed, comprising sulphonamido-substituted bridged bicycloalkyl structures. The compounds are inhibitors of gamma-secretase, and hence are useful in the treatment of and/or prevention of Alzheimer's disease.
Abstract translation: 公开了一类化合物，其包含磺酰氨基取代的桥连双环烷基结构。 这些化合物是γ-分泌酶的抑制剂，因此可用于治疗和/或预防阿尔茨海默氏病。
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