System and method for cleaning noisy genetic data and determining chromosome copy number
    83.
    发明申请
    System and method for cleaning noisy genetic data and determining chromosome copy number 有权
    清除嘈杂遗传数据和确定染色体拷贝数的系统和方法

    公开(公告)号:US20080243398A1

    公开(公告)日:2008-10-02

    申请号:US12076348

    申请日:2008-03-17

    Abstract: Disclosed herein is a system and method for increasing the fidelity of measured genetic data, for making allele calls, and for determining the state of aneuploidy, in one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available. Genetic material from the target individual is acquired, amplified and the genetic data is measured using known methods. Poorly or incorrectly measured base pairs, missing alleles and missing regions are reconstructed using expected similarities between the target genome and the genome of genetically related individuals. In accordance with one embodiment of the invention, incomplete genetic data from an embryonic cell are reconstructed at a plurality of loci using the more complete genetic data from a larger sample of diploid cells from one or both parents, with or without haploid genetic data from one or both parents. In another embodiment of the invention, the chromosome copy number can be determined from the measured genetic data of a single or small number of cells, with or without genetic information from one or both parents. In another embodiment of the invention, these determinations are made for the purpose of embryo selection in the context of in-vitro fertilization. In another embodiment of the invention, the genetic data can be reconstructed for the purposes of making phenotypic predictions.

    Abstract translation: 本文公开了一种系统和方法,用于增加测量的遗传数据的保真度,进行等位基因调用,并确定在一组或一组细胞中或从片段DNA中确定非整倍体的状态,其中有限数量的遗传数据 是可用的 获取,扩增来自目标个体的遗传物质,并使用已知方法测量遗传数据。 使用目标基因组与遗传相关个体的基因组之间的预期相似性来重建差或不正确测量的碱基对,缺失的等位基因和缺失区域。 根据本发明的一个实施方案,使用来自一个或两个亲本的二倍体细胞的较大样本的更完整的遗传数据,在多个基因座重建来自胚胎细胞的不完全遗传数据,具有或不具有来自一个的单倍体遗传数据 或双亲。 在本发明的另一个实施方案中,染色体拷贝数可以从单个或少数细胞的测量的遗传数据确定,具有或不具有来自一个或两个亲本的遗传信息。 在本发明的另一个实施方案中,这些确定是为了在体外受精的背景下进行胚胎选择的目的。 在本发明的另一个实施方案中,为了进行表型预测的目的,可以重建遗传数据。

    DYNAMIC NETWORKING BY MATCHING PROFILE INFORMATION
    84.
    发明申请
    DYNAMIC NETWORKING BY MATCHING PROFILE INFORMATION 审中-公开
    通过匹配资料信息进行动态网络化

    公开(公告)号:US20080154924A1

    公开(公告)日:2008-06-26

    申请号:US11956767

    申请日:2007-12-14

    Applicant: Jun Ding Jing Xu

    Inventor: Jun Ding Jing Xu

    CPC classification number: G06F16/9535

    Abstract: of a communication network. A message sender can attach a user-selected profile to a publicly-broadcasted message. A message viewer can read the publicly-broadcasted message only if the viewer's profile matches the sender's profile attached to the message. When a sender profile and viewer profile match, a communication channel is established between the sender and viewer. The sender's and viewer's profiles are registered on an open directory to which all parties, even parties unknown to each other, have access. The open directory structure is used in creating a header file, also referred to herein as a “stamp,” that is attached to messages or requests generated by the users. The selection of categories to be included in the header file is a procedure that is independent from the creation of the message. The header file can be combined dynamically at the point of sending the message by a message sender or at the point of searching messages by a message viewer. The messages may include text, graphics, audio or video. The broadcasting of the messages may occur via the Internet, radio, satellite, cable, and wired or wireless telephone networks.

    Abstract translation: 的通信网络。 消息发送者可以将用户选择的配置文件附加到公开广播的消息。 只有当观众的个人资料与发送者的个人资料相符时,才能阅读公开播出的消息。 当发送者简档和查看器配置文件匹配时,在发送者和查看者之间建立通信信道。 发件人和查看者的个人资料注册在一个公开的目录下,所有各方甚至彼此未知的各方都可以访问。 打开的目录结构用于创建标题文件,这里也称为附加到用户生成的消息或请求的“标记”。 要包括在头文件中的类别的选择是独立于消息创建的过程。 头文件可以在消息发送者发送消息时或在消息查看器搜索消息时动态组合。 消息可以包括文本,图形,音频或视频。 消息的广播可以通过因特网,无线电,卫星,有线和有线或无线电话网络进行。

    LENS BARREL ASSEMBLY
    85.
    发明申请
    LENS BARREL ASSEMBLY 有权
    镜头组合

    公开(公告)号:US20080044172A1

    公开(公告)日:2008-02-21

    申请号:US11565518

    申请日:2006-11-30

    Abstract: A lens barren assembly for a camera is disclosed. The lens barrel assembly comprises a lens barrel, at least one optical element disposed within the lens barrel, and an actuator configured to move the optical element. The actuator can be disposed entirely or partially within the lens barrel. The actuator can be a MEMS actuator, such as a MEMS actuator that is formed at least partially of silicon. The optical element can be a lens.

    Abstract translation: 公开了一种用于相机的透镜残余组件。 镜筒组件包括透镜镜筒,设置在透镜镜筒内的至少一个光学元件以及被配置为移动光学元件的致动器。 致动器可以完全地或部分地设置在镜筒内。 致动器可以是MEMS致动器,例如至少部分地由硅形成的MEMS致动器。 光学元件可以是透镜。

    Direct-sequence CDMA method and device
    86.
    发明授权
    Direct-sequence CDMA method and device 失效
    直接CDMA方法和装置

    公开(公告)号:US07110352B2

    公开(公告)日:2006-09-19

    申请号:US10731688

    申请日:2003-12-09

    Abstract: In code division multiple access communications wherein a plurality of data streams carrying a plurality of transmit symbols are spread by a plurality of assigned spread code, the data streams are divided into a plurality of data blocks and a plurality of prefixes in symbol-level are added to the data blocks prior to the data streams being spread and combined for transmission. At the receive side, the prefixes are removed from the received data stream in the time domain and the prefix-removed data stream is converted into a transformed signal in the frequency domain. A feed-forward filter is used to implement a joint equalization and despreading operation by element-by-element multiplications in frequency domain. A feedback filter is used to remove the inter-symbol interference and update the feed-forward filter through a feedback loop.

    Abstract translation: 在码分多址通信中,其中携带多个发送符号的多个数据流由多个分配的扩展码扩展,将数据流分成多个数据块,并且添加符号级中的多个前缀 在数据流被传播和组合用于传输之前到数据块。 在接收侧,在时域中从接收的数据流中去除前缀​​,并将前缀去除的数据流转换成频域中的变换信号。 前馈滤波器用于通过频域中的逐个元素乘法来实现联合均衡和解扩操作。 反馈滤波器用于消除符号间干扰,并通过反馈回路更新前馈滤波器。

    Text segmentation with multiple granularity levels
    90.
    发明授权
    Text segmentation with multiple granularity levels 有权
    具有多个粒度级别的文本分割

    公开(公告)号:US08892420B2

    公开(公告)日:2014-11-18

    申请号:US13298941

    申请日:2011-11-17

    Abstract: Text processing includes: segmenting received text based on a lexicon of smallest semantic units to obtain medium-grained segmentation results; merging the medium-grained segmentation results to obtain coarse-grained segmentation results, the coarse-grained segmentation results having coarser granularity than the medium-grained segmentation results; looking up in the lexicon of smallest semantic units respective search elements that correspond to segments in the medium-grained segmentation results; and forming fine-grained segmentation results based on the respective search elements, the fine-grained segmentation results having finer granularity than the medium-grained segmentation results.

    Abstract translation: 文本处理包括:基于最小语义单元的词典对接收的文本进行分段,以获得中粒度分割结果; 合并中粒度分割结果以获得粗粒度分割结果,粗粒度分割结果具有比中粒度分割结果更粗糙的粒度; 在最小语义单元的词典中查找与中粒度分割结果中的段对应的相应搜索元素; 并且基于相应的搜索元素形成细粒度分割结果,细粒度分割结果具有比中粒度分割结果更精细的粒度。

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