Image display apparatus
    1.
    发明授权
    Image display apparatus 有权
    图像显示装置

    公开(公告)号:US08830696B2

    公开(公告)日:2014-09-09

    申请号:US13222511

    申请日:2011-08-31

    IPC分类号: H05K7/02

    摘要: An image display apparatus according to the present invention includes a housing, a front frame provided forward of the housing, and a display assembly accommodated in the housing. The display assembly includes a display and a transparent plate provided forward of the display. The transparent plate is larger in outer dimension than the display and has a flange portion extending outward with respect to an outer edge of the display. A seal member is interposed between the flange portion and an outer peripheral portion of the housing. When the housing and the front frame are fastened to each other, a front surface of the flange portion of the transparent plate is brought into pressure contact with a rear surface of the front frame, and the seal member is sandwiched between the front frame and the housing with a pressure applied thereto.

    摘要翻译: 根据本发明的图像显示装置包括壳体,设置在壳体前方的前框架和容纳在壳体中的显示组件。 显示组件包括显示器和设置在显示器前方的透明板。 透明板的外形尺寸大于显示器,并且具有相对于显示器的外边缘向外延伸的凸缘部分。 密封构件插入在凸缘部和壳体的外周部之间。 当壳体和前框架彼此紧固时,透明板的凸缘部分的前表面与前框架的后表面压力接触,并且密封构件被夹在前框架和 具有施加压力的壳体。

    Cell-based assay for G-protein-coupled receptor-mediated activity employing a mutated cyclic nucleotide-gated ion channel and a membrane potential dye
    3.
    发明授权
    Cell-based assay for G-protein-coupled receptor-mediated activity employing a mutated cyclic nucleotide-gated ion channel and a membrane potential dye 有权
    使用突变的环核苷酸门控离子通道和膜电位染料的G蛋白偶联受体介导活性的基于细胞的测定

    公开(公告)号:US07384755B2

    公开(公告)日:2008-06-10

    申请号:US11492216

    申请日:2006-07-25

    申请人: Yong Yao Liang Cao

    发明人: Yong Yao Liang Cao

    IPC分类号: G01N33/53 G01N33/566

    摘要: Disclosed are compositions and methods for their use, such as in identifying G-protein-coupled receptors, ligands and compounds that modulate the activities of G-protein-coupled receptors. The compositions and methods employ cyclic nucleotide-gated channels and fluorescence dyes in detecting changes of intracellular cAMP levels in response to the stimulation of G-protein-coupled receptors. Activation of the G-protein-coupled receptors can be detected in a variety of assays, including cell-based imaging assays with fluorescence microscopes and high throughput assays with multi-well plates and fluorescence plate readers.

    摘要翻译: 公开了其用途的组合物和方法,例如鉴定G-蛋白偶联受体,调节G蛋白偶联受体活性的配体和化合物。 组合物和方法使用环状核苷酸门控通道和荧光染料来检测响应于G蛋白偶联受体的刺激的细胞内cAMP水平的变化。 可以在多种测定中检测G蛋白偶联受体的激活,包括使用荧光显微镜的基于细胞的成像测定和具有多孔板和荧光板读数器的高通量测定。

    Gαq protein variants and their use in the analysis and discovery of agonists and antagonists of chemosensory receptors
    5.
    发明授权
    Gαq protein variants and their use in the analysis and discovery of agonists and antagonists of chemosensory receptors 有权
    Galphaq蛋白质变体及其在分析和发现化学感应受体激动剂和拮抗剂中的用途

    公开(公告)号:US07041457B2

    公开(公告)日:2006-05-09

    申请号:US09989497

    申请日:2001-11-21

    申请人: Yong Yao Hong Xu

    发明人: Yong Yao Hong Xu

    IPC分类号: G01N33/53

    CPC分类号: C07K14/4722 C07K2319/00

    摘要: The invention provides a series of Gαq protein variants that functionally couple to sensory cell receptors such as taste GPCRs (TRs) and olfactory GPCRs (ORs) in an overly promiscuous manner. According to the invention, the functional coupling can be determined, for example, by measuring changes in intracellular IP3, or calcium. In a particular embodiment, the Gαq protein variants can be expressed in mammalian cell lines or Xenopus oocytes, and then evaluated using calcium fluorescence imaging and electrophysiological recording.

    摘要翻译: 本发明提供了一系列以过度混杂的方式功能性地与感觉细胞受体例如味道GPCR(TR))和嗅觉GPCR(OR)偶联的Galpha蛋白质变体。 根据本发明,功能性偶联可以通过例如测量细胞内IP3或钙的变化来确定。 在一个具体实施方案中,GalphaQ蛋白变体可以在哺乳动物细胞系或非洲爪蟾卵母细胞中表达,然后使用钙荧光成像和电生理记录进行评估。

    G&agr;q protein variants and their use in the analysis and discovery of agonists and antagonists of chemosensory receptors
    6.
    发明授权
    G&agr;q protein variants and their use in the analysis and discovery of agonists and antagonists of chemosensory receptors 有权
    Galphaq蛋白质变体及其在分析和发现化学感应受体激动剂和拮抗剂中的用途

    公开(公告)号:US06818747B2

    公开(公告)日:2004-11-16

    申请号:US09984292

    申请日:2001-10-29

    申请人: Yong Yao Hong Xu

    发明人: Yong Yao Hong Xu

    IPC分类号: C07K1900

    CPC分类号: C07K14/4722 C07K2319/00

    摘要: The invention provides a series of G&agr;q protein variants that functionally couple to sensory cell receptors such as taste GPCRs (TRs) and olfactory GPCRs (ORs) in an overly promiscuous manner. According to the invention, the functional coupling can be determined, for example, by measuring changes in intracellular IP3, or calcium. In a particular embodiment, the G&agr;q protein variants can be expressed in mammalian cell lines or Xenopus oocytes, and then evaluated using calcium fluorescence imaging and electrophysiological recording.

    摘要翻译: 本发明提供了一系列Galphaq蛋白质变体,其以过度混杂的方式功能性地耦合到感觉细胞受体,例如味道GPCR(TR)和嗅觉GPCR(OR))。 根据本发明,功能性偶联可以通过例如测量细胞内IP3或钙的变化来确定。 在一个具体实施方案中,Galphaq蛋白质变体可以在哺乳动物细胞系或非洲爪蟾卵母细胞中表达,然后使用钙荧光成像和电生理记录进行评估。

    Method for low thermal budget metal filling and planarization of contacts vias and trenches
    7.
    发明授权
    Method for low thermal budget metal filling and planarization of contacts vias and trenches 失效
    用于低热预算金属填充和平面化接触通孔和沟槽半导体晶片的方法和装置

    公开(公告)号:US06313027B1

    公开(公告)日:2001-11-06

    申请号:US08944140

    申请日:1997-10-06

    IPC分类号: H01L214763

    摘要: The present invention pertains to a carrier layer and a contact enabled by the carrier layer which enables the fabrication of aluminum (including aluminum alloys and other conductive materials having a similar melting point) electrical contacts in multilayer integrated circuit vias, through holes, or trenches having an aspect ratio greater than one. In fact, the structure has been shown to enable such contact fabrication in vias, through holes, and trenches having aspect ratios as high as at least 5:1, and should be capable of filing apertures having aspect ratios up to about 12:1. The carrier layer, in addition to permitting the formation of a conductive contact at high aspect ratio, provides a diffusion barrier which prevents the aluminum from migrating into surrounding substrate material which operates in conjunction with the electrical contact. The carrier layer preferably comprises a layer formed by ionizing the flux of sputter deposition material, partially reacting the flux with a gas, and depositing the resulting material on a substrate.

    摘要翻译: 本发明涉及载体层和由载体层实现的接触,其能够在多层集成电路通孔,通孔或沟槽中制造具有类似熔点的铝(包括铝合金和具有相似熔点的其它导电材料)电接触,所述多层集成电路通孔,通孔或沟槽具有 长宽比大于1。 事实上,已经显示了这种结构能够使通孔,通孔和沟槽中的这种接触制造具有高达至少5:1的纵横比,并且应该能够填充具有高达约12:1的纵横比的孔。 除了允许以高纵横比形成导电接触之外,载体层提供了扩散阻挡层,其防止铝迁移到与电触点一起操作的周围基底材料中。 载体层优选包括通过电离溅射沉积材料的焊剂形成的层,使焊剂与气体部分地反应,并将所得材料沉积在衬底上。

    Directed content presentation
    9.
    发明授权
    Directed content presentation 有权
    定向内容演示

    公开(公告)号:US09451308B1

    公开(公告)日:2016-09-20

    申请号:US13556117

    申请日:2012-07-23

    申请人: Zhenyu Liu Yong Yao

    发明人: Zhenyu Liu Yong Yao

    IPC分类号: H04H60/32 H04N21/262

    摘要: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for content presentation. One of the methods includes determining current programming being presented to a user from a first device, wherein the determining includes receiving information from the first device associated with the current programming being presented; determining one or more sponsored content items to provide to a second device, wherein the one or more sponsored content items are identified as associated with the current programming including determining that one or more presentation criteria as specified by a respective sponsored content provider have been satisfied; and providing the one or more sponsored content items to the second device.

    摘要翻译: 方法,系统和装置,包括在计算机存储介质上编码的计算机程序,用于内容呈现。 所述方法之一包括确定从第一设备呈现给用户的当前节目,其中所述确定包括从所述第一设备接收与正在呈现的当前节目相关联的信息; 确定一个或多个赞助的内容项目以提供给第二设备,其中所述一个或多个赞助的内容项目被识别为与当前节目相关联,包括确定已经满足由相应的赞助内容提供商指定的一个或多个呈现准则; 以及将所述一个或多个赞助的内容项目提供给所述第二设备。