Push button switch
    81.
    发明授权
    Push button switch 失效
    按钮开关

    公开(公告)号:US5201824A

    公开(公告)日:1993-04-13

    申请号:US820451

    申请日:1992-01-13

    IPC分类号: H01H13/705

    摘要: A push button switch including a case, a key top fastened to the case, an elastic member disposed between the case and the key top and acting to upwards urge the key top and a contact portioned so as to confront a spring member fastened to an operation member of the key top so that the contact portion is pressed by the spring member when the key top is depressed, the push button switch comprising: a movable member disposed between the operation member of the key top and a projection wall of the case whereby the operation member and the movable member can be moved with respect to each other and the movable member and the projection wall can be moved with respect to each other.

    摘要翻译: 一种按钮开关,包括壳体,紧固到壳体的键顶,弹性构件,其设置在壳体和键顶之间,并且用于向上推动键顶和接触部分,以抵抗固定到操作的弹簧构件 键顶部的构件,使得当键顶被按压时接触部分被弹簧构件按压,按钮开关包括:可移动构件,设置在键顶的操作构件和壳体的突出壁之间, 操作构件和可动构件可以相对于彼此移动,并且可移动构件和突出壁可以相对于彼此移动。

    Push button switch
    82.
    发明授权
    Push button switch 失效
    按钮开关

    公开(公告)号:US5120923A

    公开(公告)日:1992-06-09

    申请号:US584558

    申请日:1990-09-18

    IPC分类号: H01H13/20 H01H13/705

    摘要: A push button switch including a case, a key top fastened to the case, an elastic member disposed between the case and the key top and acting to upwards urge the key top and a contact portioned so as to confront a spring member fastened to an operation member of the key top so that the contact portion is pressed by the spring member when the key top is depressed, the push button switch comprising: a movable member disposed between the operation member of the key top and a projection wall of the case whereby the operation member and the movable member can be moved with respect to each other and the movable member and the projection wall can be moved with respect to each other.

    摘要翻译: 一种按钮开关,包括壳体,紧固到壳体的键顶,弹性构件,其设置在壳体和键顶之间,并且用于向上推动键顶和接触部分,以抵抗固定到操作的弹簧构件 键顶部的构件,使得当键顶被按压时接触部分被弹簧构件按压,按钮开关包括:可移动构件,设置在键顶的操作构件和壳体的突出壁之间, 操作构件和可动构件可以相对于彼此移动,并且可移动构件和突出壁可以相对于彼此移动。

    3-[1,4]oxazepane-4-pyrimidone derivatives
    84.
    发明授权
    3-[1,4]oxazepane-4-pyrimidone derivatives 有权
    3- [1,4]氧氮杂环庚烷-4-嘧啶酮衍生物

    公开(公告)号:US09108957B2

    公开(公告)日:2015-08-18

    申请号:US13262396

    申请日:2010-04-01

    摘要: A compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: wherein Z represents nitrogen atom, C—F or the like; R1 represents a C1-C3 alkyl group; Y represents oxygen atom or N—R7; R2, R3, R4, R5, R6 and R7 each independently represents hydrogen atom, a C1-C6 alkyl group, or a group represented by the formula (II): which is used for preventive and/or therapeutic treatment of a disease caused by tau protein kinase 1 hyperactivity such as a neurodegenerative diseases (e.g. Alzheimer disease).

    摘要翻译: 由式(I)表示的化合物或其药学上可接受的盐:其中Z表示氮原子,C-F等; R1表示C1-C3烷基; Y表示氧原子或N-R7; R2,R3,R4,R5,R6和R7各自独立地表示氢原子,C1-C6烷基或由式(II)表示的基团:其用于预防和/或治疗由 tau蛋白激酶1多动症如神经变性疾病(如阿兹海默症)。

    2-substituted-6-heterocyclic pyrimidone derivatives as tau protein kinase 1 inhibitors
    86.
    发明授权
    2-substituted-6-heterocyclic pyrimidone derivatives as tau protein kinase 1 inhibitors 失效
    作为tau蛋白激酶1抑制剂的2-取代-6-杂环嘧啶酮衍生物

    公开(公告)号:US08592417B2

    公开(公告)日:2013-11-26

    申请号:US12518997

    申请日:2007-12-26

    IPC分类号: A61K31/535 C07D413/14

    CPC分类号: C07D413/14

    摘要: A compound represented by the formula (I), an optically active isomer thereof, or a pharmaceutical acceptable salt thereof: wherein each R1 represents hydrogen atom or the like; X represents oxygen atom or the like; A represents a C3-C7 cycloalkyl group, a C6-C10 aryl group or a heterocyclic group; R6 represents a halogen atom or the like; s represents 0 or an integer of 1 to 5; Q represents a pyridine ring which may be substituted or pyrimidine ring; and R2 represents hydrogen atom or the like, which is used for preventive and/or therapeutic treatment of a disease caused by abnormal activity of tau protein kinase 1 such as a neurodegenerative diseases (e.g. Alzheimer disease).

    摘要翻译: 由式(I)表示的化合物或其光学活性异构体或其药学上可接受的盐:其中每个R 1表示氢原子等; X表示氧原子等; A表示C 3 -C 7环烷基,C 6 -C 10芳基或杂环基; R6表示卤素原子等; s表示0或1〜5的整数, Q表示可以被取代或嘧啶环的吡啶环; R2代表氢原子等,其用于预防和/或治疗由tau蛋白激酶1的异常活性引起的疾病,例如神经变性疾病(例如阿尔茨海默病)。