公开(公告)号：US07820824B2

公开(公告)日：2010-10-26

申请号：US11675037

申请日：2007-02-14

Applicant: Wai-Yee Leung ,  Ching-Ying Cheung ,  Stephen Yue

Inventor： Wai-Yee Leung ,  Ching-Ying Cheung ,  Stephen Yue

IPC: C07D215/38

CPC classification number: G01N1/30 ,  A61K41/0057 ,  C07C66/02 ,  C07D209/08 ,  C07D209/12 ,  C07D209/14 ,  C07D209/16 ,  C07D209/18 ,  C07D209/24 ,  C07D209/54 ,  C07D209/60 ,  C07D209/96 ,  C07D401/04 ,  C07D403/06 ,  C07D403/12 ,  C07D403/14 ,  C07D417/06 ,  C07D417/14 ,  C07D471/04 ,  C07D498/04 ,  C07K1/13 ,  C09B23/02 ,  C09B23/06 ,  C09B23/083 ,  C09B23/107 ,  C12Q1/6825 ,  C40B70/00 ,  G01N31/22 ,  G01N33/533 ,  G01N33/535 ,  G01N33/58 ,  G01N33/581 ,  G01N33/582 ,  G01N2001/302 ,  Y10T436/143333

Abstract: Chemically reactive carbocyanine dyes incorporating an indolium ring moiety that is substituted at the 3-position by a reactive group or by a conjugated substance, and their uses, are described. Conjugation through this position results in spectral properties that are uniformly superior to those of conjugates of spectrally similar dyes wherein attachment is at a different position. The invention includes derivative compounds having one or more benzo nitrogens.

公开(公告)号：US07776529B2

公开(公告)日：2010-08-17

申请号：US11005861

申请日：2004-12-06

Applicant: Jason Alfred Dallwig ,  David Carl Hagen ,  Ching-Ying Cheung ,  Gerald Alan Thomas ,  Stephen Yue

Inventor： Jason Alfred Dallwig ,  David Carl Hagen ,  Ching-Ying Cheung ,  Gerald Alan Thomas ,  Stephen Yue

IPC: A61K31/4709 ,  C07D215/12 ,  C12Q1/68

CPC classification number: C09B23/164 ,  C07D277/64 ,  C07D417/06 ,  C09B23/0008 ,  C09B23/04 ,  C09B23/06 ,  C09B23/107 ,  C12Q1/6806 ,  C12Q1/6876 ,  C12Q2600/16 ,  G01N33/5308 ,  Y10T436/143333

Abstract: Cyanine dye compounds having a substituted methine moiety that are nucleic acid stains, particularly for fluorescent staining of RNA, including compounds having the formula where R1 is a C1-C6 alkyl, sulfoalkyl, carboxyalkyl or C1-C6 alkoxy; each R2 is independently selected from the group consisting of H, C1-C6 alkyl, C1-C6 alkoxy, fused benzo, trifluoromethyl, amino, sulfo, carboxy and halogen, that is optionally further substituted; at least one of R3, R4, and R5 is an alkyl, aryl, heteroaryl, cyclic, or heterocyclic moiety that is optionally substituted by alkyl, amino, aminoalkyl, carboxy, nitro, or halogen; and the remaining R3, R4 or R5 are hydrogen; X is S, O, or Se; and D is a substituted or unsubstituted pyridinium, quinolinium or benzazolium moiety.

Abstract translation: 具有作为核酸染色的取代的次甲基部分的花青染料化合物，特别是用于RNA的荧光染色，包括具有下式的化合物，其中R 1是C 1 -C 6烷基，磺基烷基，羧基烷基或C 1 -C 6烷氧基; 每个R 2独立地选自H，C 1 -C 6烷基，C 1 -C 6烷氧基，稠合的苯并，三氟甲基，氨基，磺基，羧基和卤素，其任选进一步被取代; R 3，R 4和R 5中的至少一个是任选被烷基，氨基，氨基烷基，羧基，硝基或卤素取代的烷基，芳基，杂芳基，环状或杂环部分; 剩余的R3，R4或R5是氢; X是S，O或Se; 并且D是取代或未取代的吡啶鎓，喹啉鎓或苯并咪唑鎓部分。

公开(公告)号：US20100143917A1

公开(公告)日：2010-06-10

申请号：US12573809

申请日：2009-10-05

Applicant: Jolene A. BRADFORD ,  Ching-Ying CHEUNG ,  Shih-Jung HUANG ,  Patrick R. PINSON ,  Stephen T. YUE

Inventor： Jolene A. BRADFORD ,  Ching-Ying CHEUNG ,  Shih-Jung HUANG ,  Patrick R. PINSON ,  Stephen T. YUE

IPC: C12Q1/68 ,  C07D401/04 ,  C07D401/08 ,  C07D413/08

CPC classification number: G01N33/582 ,  C07D215/10 ,  C07D215/227 ,  C07D277/72 ,  C07D277/74 ,  C07D417/04 ,  C07D417/06 ,  C07D417/14 ,  C12Q1/6876 ,  G01N21/6428 ,  G01N21/6486 ,  G01N2021/6439 ,  G01N2201/06113 ,  Y10T436/143333

Abstract: Chemical compounds having a high selectivity for double stranded DNA over RNA and single stranded DNA are disclosed. The chemical compounds are stains that become fluorescent upon illumination and interaction with double stranded DNA, but exhibit reduced or no fluorescence in the absence of double stranded DNA. The compounds can be used in a variety of biological applications to qualitatively or quantitatively assay DNA, even in the presence of RNA.

Abstract translation: 公开了对RNA和单链DNA具有对双链DNA的高选择性的化合物。 化学化合物是在照射时变成荧光并与双链DNA相互作用的污渍，但在不存在双链DNA的情况下表现出减少的或没有荧光。 该化合物可用于各种生物学应用中，以定性或定量测定DNA，即使在RNA的存在下。

公开(公告)号：US20100011126A1

公开(公告)日：2010-01-14

申请号：US12496560

申请日：2009-07-01

Applicant: Ivy Pei-Shan Hsu ,  David Chun-Ying Cheung ,  Rajkumar Ramniranjan Jalan

Inventor： Ivy Pei-Shan Hsu ,  David Chun-Ying Cheung ,  Rajkumar Ramniranjan Jalan

IPC: G06F15/173

CPC classification number: H04L67/1002 ,  H04L67/1008 ,  H04L67/1012 ,  H04L67/1021

Abstract: A global server load balancing (GSLB) switch serves as a proxy to an authoritative DNS communicates with numerous site switches which are coupled to host servers serving specific applications. The GSLB switch receives from site switches operational information regarding host servers within the site switches neighborhood. When a client program requests a resolution of a host name, the GSLB switch, acting as a proxy of an authoritative DNS, returns one or more ordered IP addresses for the host name. The IP addresses are ordered using metrics that include the information collected from the site switches. In one instance, the GSLB switch places the address that is deemed “best” at the top of the list.

Abstract translation: 全局服务器负载平衡（GSLB）交换机用作授权DNS的代理，与许多站点交换机进行通信，这些站点交换机与服务于特定应用程序的主机服务器相连接。 GSLB交换机从站点交换机接收关于站点交换机附近的主机服务器的操作信息。 当客户端程序请求解析主机名时，作为权威DNS的代理的GSLB交换机返回主机名的一个或多个有序IP地址。 IP地址使用包含从站点交换机收集的信息的度量来排序。 在一个实例中，GSLB开关将地址视为“最佳”位于列表的顶部。

公开(公告)号：US20080145526A1

公开(公告)日：2008-06-19

申请号：US11952867

申请日：2007-12-07

Applicant: Fei Mao ,  Wai-Yee Leung ,  Ching-Ying Cheung ,  Jie Yang

Inventor： Fei Mao ,  Wai-Yee Leung ,  Ching-Ying Cheung ,  Jie Yang

IPC: B05D5/06 ,  C07F15/00 ,  C09K11/06

CPC classification number: C07F15/0053 ,  C09B57/10 ,  G01N33/6839 ,  G01N2458/40

Abstract: Luminescent metal complexes, methods of producing and/or designing same, methods of using same, and associated technology, are disclosed herein. A luminescent metal complex may be useful for a variety of applications, such as staining, detection, and/or identification, for example, of substances, such as poly(amino acids), for example. Further by way of example, a luminescent metal complex may be useful for staining, detecting, and/or identifying poly(amino acids) that are associated with any of various environments, such as a gel or a gel matrix, such as any associated with SDS-PAGE, for example, a surface environment, such as any associated with western blot, for example, and/or the like. Compositions, solutions, and kits comprising a luminescent metal complex are also disclosed herein.

Abstract translation: 本文公开了发光金属络合物，其制备方法和/或设计方法，使用方法及相关技术。 发光金属络合物可用于各种应用，例如染色，检测和/或鉴定，例如物质，例如聚（氨基酸）。 进一步作为示例，发光金属络合物可用于染色，检测和/或鉴定与各种环境中的任何环境相关的聚（氨基酸），例如凝胶或凝胶基质，例如任何与 例如，SDS-PAGE，例如表面环境，例如与western印迹相关的任何例如和/或类似物。 本文还公开了包含发光金属络合物的组合物，溶液和试剂盒。

公开(公告)号：US07193377B2

公开(公告)日：2007-03-20

申请号：US10794157

申请日：2004-03-04

Applicant: Patrick Ying Cheung Fung

Inventor： Patrick Ying Cheung Fung

IPC: H02P1/18

CPC classification number: H02P7/29

Abstract: A motor drive circuit includes a switching circuit having an input node that receives a drive signal and a control node that receives a control signal. The switching circuit couples the input node to an output node responsive to the control signal. A bias element receives an input signal and is coupled to the output node of the switching circuit. The bias element automatically develops a bias voltage on the output responsive to the input signal. The drive circuit may be used, for example, in a motor control system to control the speed of a DC motor, such as in a power supply for a computer system.

Abstract translation: 电动机驱动电路包括具有接收驱动信号的输入节点和接收控制信号的控制节点的开关电路。 开关电路响应于控制信号将输入节点耦合到输出节点。 偏置元件接收输入信号并耦合到开关电路的输出节点。 偏置元件响应于输入信号自动产生输出上的偏置电压。 驱动电路例如可以用在电动机控制系统中，以控制直流电动机的速度，例如用于计算机系统的电源。

公开(公告)号：US20060151755A1

公开(公告)日：2006-07-13

申请号：US11371120

申请日：2006-03-08

Applicant: Chi-Ming Chan ,  Kai-Mo Ng ,  Catherine Wong ,  Ying Cheung

Inventor： Chi-Ming Chan ,  Kai-Mo Ng ,  Catherine Wong ,  Ying Cheung

IPC: H01B1/12

CPC classification number: H01B1/22 ,  H05K1/0257 ,  H05K1/0259 ,  H05K1/167 ,  H05K2201/0738 ,  Y10T428/257 ,  Y10T428/31663

Abstract: The invention provides a process for preparing an overvoltage protection material comprising: (i) preparing a mixture comprising a polymer binder precursor and a conductive material; and (ii) heating the mixture to cause reaction of the polymer binder precursor and generate a polymer matrix having conductive material dispersed therein, wherein the polymer binder precursor is chosen such that substantially no solvent is generated during the reaction.