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81.发明授权Apparatus for atomizing a sample including a slidable pressure maintaining arrangement 失效用于雾化样品的装置，包括可滑动的压力保持装置
公开(公告)号：US4432643A
公开(公告)日：1984-02-21
申请号：US245162
申请日：1981-03-18
申请人： Hideaki Koizumi , Yosio Taiti , Kazuo Moriya , Katsuhito Harada , Kazuo Sato
发明人： Hideaki Koizumi , Yosio Taiti , Kazuo Moriya , Katsuhito Harada , Kazuo Sato
CPC分类号： G01N21/74
摘要： An apparatus for atomizing a sample comprises a cuvette of heating material into which a sample is introduced, a pair of electrodes of supplying an electric current to the cuvette, thereby heating and atomizing the sample, supports of supporting the pair of the electrodes, a means for supplying light to the atomized sample and a means of slidably maintaining at least one of the pair of the electrodes against the cuvette in a predetermined range of contact pressures, where the heating temperature of the cuvette can be maintained constant with improved reproducibility of analytical values.
摘要翻译： 用于对样品进行雾化的装置包括：向其中引入样品的加热材料的比色皿，向比色皿供应电流的一对电极，从而加热和雾化样品，支撑一对电极的支撑体， 用于向雾化样品提供光，以及在预定接触压力范围内可滑动地将一对电极中的至少一个电极抵靠反应杯的装置，其中比色杯的加热温度可以通过分析值的再现性得到改善而保持恒定 。
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公开(公告)号：US4202628A
公开(公告)日：1980-05-13
申请号：US781938
申请日：1977-03-28
申请人： Hideaki Koizumi , Kazuo Moriya
发明人： Hideaki Koizumi , Kazuo Moriya
CPC分类号： G01N21/74 , G01N2021/151
摘要： A cuvette used in a flameless atomizer is hollow and includes an opening at both ends and a hole in a radial direction substantially at its central portion. The cuvette is made of a conductive material and Joule-heated by currents flowing therethrough. The interior of the cuvette is divided substantially into three sections: a sample mount section at which a sample introduced through the hole of the cuvette is disposed; a light beam path section through which light incident from the opening at one end of the cuvette passes and goes out of the opening at the other end; and an absorption cell section at which the light beam path section intersects with atomic vapors generated from the sample disposed at the sample mount section. The electric resistance of the cuvette is made smaller at the sample mount section than at a portion near the absorption cell section. This allows the higher temperature of the portions near the absorption cell section than that of the sample mount section. Therefore, almost all of the atomic vapors in the cuvette exist at the absorption cell portion, and the application of a magnetic field to the absorption cell section allows a great improvement in analysis precision and sensitivity of the flameless atomizer for atomic absorption analysis using a Zeeman effect.
摘要翻译： 在无焰雾化器中使用的比色杯是中空的，并且包括在两端的开口和在径向方向上的大致在其中心部分的孔。 试管由导电材料制成，并由流过其中的电流进行焦耳加热。 试管的内部基本上分为三个部分：样品安装部分，其中设置通过反应杯的孔引入的样品; 光束路径部分，通过所述光束路径部分从所述反应杯的一端处的所述开口入射的光在所述另一端通过并离开所述开口; 以及吸收单元部分，光束路径部分与从设置在样品安装部分处的样品产生的原子蒸汽相交。 在样品安装部分，反应杯的电阻比吸收单元部分附近的电阻小。 这允许吸收单元部分附近的部分的温度高于样品安装部分的温度。 因此，比色皿中的几乎所有的原子蒸汽都存在于吸收单元部分，并且向吸收单元部分施加磁场允许使用塞曼对无焰雾化器进行原子吸收分析的分析精度和灵敏度大大提高 影响。
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公开(公告)号：US09423416B2
公开(公告)日：2016-08-23
申请号：US14416968
申请日：2012-08-28
摘要： Provided is a scanning probe microscope that takes measurements at high spatial resolution on physical information such as array structure of water molecules at a specimen-culture fluid interface in a culture fluid as well as irregularities of the surface of a specimen and composition distribution and array structure of molecules, proteins, etc. even in the atmosphere, an ambient air, vacuum, among others. The scanning probe microscope includes: a probing needle (1); a specimen holder (11) in which a specimen (3) is mounted; an oscillator (2) that produces a periodic oscillation to change the probing needle position; a pulse oscillation type laser light source (27, 28) that emits light toward a spot, which is put under measurement by the probing needle, on the specimen; a detector (25) that measures intensity of output light which is output from the specimen by energy spectroscopy; and a control device (26). The control device decreases amplitude of the periodic oscillation to change the probing needle position by the oscillator, shortens a relative distance between the probing needle and the specimen, and synchronizes shortening of the distance between the probing needle and the specimen and emission of pulse oscillation laser light, thus optimizing efficiency of tip-enhanced detection.
摘要翻译： 提供了一种扫描探针显微镜，其以高空间分辨率对物理信息进行测量，例如在培养液中的标本培养液界面处的水分子的阵列结构以及样品表面的不规则性以及组成分布和阵列结构 的分子，蛋白质等，甚至在大气中，环境空气，真空等。 扫描探针显微镜包括：探针（1）; 其中安装有试样（3）的试样保持器（11） 振荡器（2），其产生周期性振荡以改变探针位置; 对被检测体进行测量的点发光的脉冲振荡型激光光源（27,28）; 检测器（25），其通过能量谱测量从所述样本输出的输出光的强度; 和控制装置（26）。 控制装置减小周期性振荡的振幅，通过振荡器改变探针位置，缩短探针与试样之间的相对距离，同步缩短探针与试样之间的距离，并发出脉冲振荡激光 轻，从而优化提示增强检测的效率。
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公开(公告)号：US20150177275A1
公开(公告)日：2015-06-25
申请号：US14416968
申请日：2012-08-28
IPC分类号： G01Q10/04
摘要： Provided is a scanning probe microscope that takes measurements at high spatial resolution on physical information such as array structure of water molecules at a specimen-culture fluid interface in a culture fluid as well as irregularities of the surface of a specimen and composition distribution and array structure of molecules, proteins, etc. even in the atmosphere, an ambient air, vacuum, among others. The scanning probe microscope includes: a probing needle (1); a specimen holder (11) in which a specimen (3) is mounted; an oscillator (2) that produces a periodic oscillation to change the probing needle position; a pulse oscillation type laser light source (27, 28) that emits light toward a spot, which is put under measurement by the probing needle, on the specimen; a detector (25) that measures intensity of output light which is output from the specimen by energy spectroscopy; and a control device (26). The control device decreases amplitude of the periodic oscillation to change the probing needle position by the oscillator, shortens a relative distance between the probing needle and the specimen, and synchronizes shortening of the distance between the probing needle and the specimen and emission of pulse oscillation laser light, thus optimizing efficiency of tip-enhanced detection.
摘要翻译： 提供了一种扫描探针显微镜，其以高空间分辨率对物理信息进行测量，例如在培养液中的标本培养液界面处的水分子的阵列结构以及样品表面的不规则性以及组成分布和阵列结构 的分子，蛋白质等，甚至在大气中，环境空气，真空等。 扫描探针显微镜包括：探针（1）; 其中安装有试样（3）的试样保持器（11） 振荡器（2），其产生周期性振荡以改变探针位置; 对被检测体进行测量的点发光的脉冲振荡型激光光源（27,28）; 检测器（25），其通过能量谱测量从所述样本输出的输出光的强度; 和控制装置（26）。 控制装置减小周期性振荡的振幅，通过振荡器改变探针位置，缩短探针与试样之间的相对距离，同步缩短探针与试样之间的距离，并发出脉冲振荡激光 轻，从而优化提示增强检测的效率。
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公开(公告)号：US20080237459A1
公开(公告)日：2008-10-02
申请号：US12081625
申请日：2008-04-18
IPC分类号： B01D59/44
CPC分类号： H01J49/045
摘要： An ion source includes a body having a gas passage and an orifice. A capillary is inserted into the gas passage so that a tip portion of the capillary extends into the orifice. A gas supplier supplies a gas into the gas passage to form a gas flow through the gas passage along the capillary and through the orifice past a tip of the capillary so that the gas flow sprays a sample solution flowing through the capillary from the tip of the capillary. A flow controller regulates a pressure of the gas in the gas passage to adjust a characteristic value F/S to a predetermined value, where F is a flow rate of the gas flow at standard conditions (20.degree. C., 1 atmosphere), and S is a difference between a cross section of the orifice and a cross section of the tip portion of the capillary in the orifice.
摘要翻译： 离子源包括具有气体通道和孔的主体。 毛细管插入到气体通道中，使得毛细管的尖端部分延伸到孔中。 气体供应商将气体供应到气体通道中以形成沿着毛细管的气体通道的气流，并且通过孔经过毛细管的尖端，使得气流从其中的尖端喷射流过毛细管的样品溶液 毛细管。 流量控制器调节气体通道中的气体的压力，以将特性值F / S调节到预定值，其中F是在标准条件（20℃，1个大气压）下的气体流量的流量， ，S是孔口的截面与孔口中的毛细管的前端部的截面的差。
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公开(公告)号：US07286870B2
公开(公告)日：2007-10-23
申请号：US09900144
申请日：2001-07-09
IPC分类号： A61B6/00
CPC分类号： A61B5/0059 , A61B5/0042 , A61B5/055 , A61B5/14552 , A61B5/14553 , A61B5/18 , A61B5/6814 , A61B5/7207 , A61B5/7228 , A61B6/03 , A61B6/507 , A61B2562/0219 , A61B2562/0233 , A61B2562/046
摘要： In an optical measurement system and imaging method adapted to measure in vivo information in a living body without harming the living body, light rays of a plurality of wavelengths which are modulated in intensity with a plurality of different frequencies are irradiated on a plurality of irradiation positions on the surface of a living body, and time-variable changes in living body transmitting light intensity levels corresponding to the respective wavelengths and the respective irradiation positions are measured at different positions on the surface of the living body. Light is utilized to image the results of the measurements, in which the measuring time is shortened by estimating fluctuation attributable to the living body, and the presence or absence of a change in measured signal can be decided easily by displaying an estimation signal and a measured signal at a time.
摘要翻译： 在适于测量活体内的体内信息而不损害生物体的光学测量系统和成像方法中，以多个不同频率强度调制的多个波长的光线照射在多个照射位置 在生物体的表面上，在生物体的表面的不同位置测量发射对应于各个波长和各个照射位置的光强度水平的生物体的随时间变化。 光被用于对测量结果进行成像，其中通过估计归因于生物体的波动来缩短测量时间，并且可以通过显示估计信号和测量的信号来容易地确定测量信号的变化的存在或不存在 信号一次。
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公开(公告)号：US20060184046A1
公开(公告)日：2006-08-17
申请号：US11371918
申请日：2006-03-10
申请人： Yuichi Yamashita , Atsushi Maki , Hideaki Koizumi
发明人： Yuichi Yamashita , Atsushi Maki , Hideaki Koizumi
IPC分类号： A61B6/00
CPC分类号： A61B5/14546 , A61B5/14553 , A61B2562/0233 , A61B2562/0242 , A61B2562/046 , G01N21/35 , G01N21/4795
摘要： An optical measurement instrument for a living body including a first light irradiator for irradiating light from a first irradiation position in a small region as considered as a plan on the surface of a head of a subject into the inside of the head in the region in the direction of depth, a second light irradiator for irradiating light from a second irradiation position in the region into the inside of the head, a first detecting for detecting the first irradiated light to pass through the head in a first detection position in the region, a second detector for detecting the second irradiated light to pass through the head in a second detection position in the region, and a calculator for multiplication or addition of a first signal and a second signal in a calculator.
摘要翻译： 一种用于生物体的光学测量仪器，包括：第一光照射器，用于将来自被摄体头部的表面上所考虑的小区域的第一照射位置的光照射到头部的内部， 深度方向，用于将来自该区域内的第二照射位置的光照射到头部内部的第二光照射器，在该区域中的第一检测位置检测第一照射光通过头部的第一检测， 第二检测器，用于检测第二照射光在区域中的第二检测位置中通过头部;以及计算器，用于在计算器中乘法或相加第一信号和第二信号。
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公开(公告)号：US20060184045A1
公开(公告)日：2006-08-17
申请号：US11371916
申请日：2006-03-10
申请人： Yuichi Yamashita , Atsushi Maki , Hideaki Koizumi
发明人： Yuichi Yamashita , Atsushi Maki , Hideaki Koizumi
IPC分类号： A61B6/00
CPC分类号： A61B5/14546 , A61B5/14553 , A61B2562/0233 , A61B2562/0242 , A61B2562/046 , G01N21/35 , G01N21/4795
摘要： An optical measurement instrument for a living body to measure dynamic change of blood of a brain includes light incident units for irradiating light on a head of a subject, a light detector for detecting a light irradiated from the light incident units and reflected within the subject, a signal processing unit for calculating a spacious distribution of signals from the subject to be measured from a signal detected by the light detector, and a display for displaying the spacious distribution of signals from the subject to be measured. Measurement points are arranged about a middle of the light incident units and the light detector, and the light incident units and the light detector are arranged such that the measurement points are arranged to form a lattice whose circumference is square.
摘要翻译： 用于测量脑的血液动态变化的生物体的光学测量仪器包括用于照射被检体头部的光入射单元，用于检测从光入射单元照射并在被检体内反射的光的光检测器， 信号处理单元，用于根据由光检测器检测到的信号计算来自待测对象的信号的宽敞分布;以及显示器，用于显示来自待测对象的信号的宽敞分布。 测量点围绕光入射单元和光检测器的中间布置，并且光入射单元和光检测器被布置成使得测量点被布置成形成圆周为正方形的格子。
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公开(公告)号：US20060178839A1
公开(公告)日：2006-08-10
申请号：US11378448
申请日：2006-03-20
IPC分类号： G06F19/00
CPC分类号： G01N21/49 , A61B5/0042 , A61B5/14553 , A61B5/7435
摘要： In order to provide an optical measurement system and an optical measurement method which is suitable for optically measuring a body to be inspected and easily obtaining an image of a desired item based on information obtained by the measurement, an optical measurement method comprising an initial display process for selectively instructing any one of selection of optical measurement, analysis of said optical measurement result and completion of a program (S1); a process for inputting items of condition including a measurement mode (S2); a process for displaying a light irradiation position and a light detection position and a state expressing measurement position relationship together with said mode (S4); a process for instructing to form a file for storing said optical measurement result; a process for instructing a measurement condition to detect light signals from the inside of a body to be inspected which is irradiated by a multi-wavelength multi-channel (S10); and a process for displaying said signals for each channel detected according to said instructed result (S11).
摘要翻译： 为了提供一种光学测量系统和光学测量方法，该光学测量系统和光学测量方法适合于光学测量待检查的物体，并且基于通过测量获得的信息容易地获得所需物品的图像，光学测量方法包括初始显示处理 用于选择性地指示光学测量的选择，所述光学测量结果的分析和程序的完成中的任何一个（S1）; 用于输入包括测量模式的条件项目的处理（S 2）; 用于显示光照射位置和光检测位置的处理以及表示测量位置关系的状态与所述模式（S 4）。 用于指示形成用于存储所述光学测量结果的文件的处理; 用于指示测量条件以从多波长多通道照射的被检体的内部检测光信号的步骤（S10）; 以及根据所述指示结果显示针对每个通道的所述信号的处理（S11）。
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90.发明授权Volition induction apparatus and input/output apparatus which use optical measuring instrument, and recording medium 有权使用光学测量仪器和记录介质的感应装置和输入/输出装置公开(公告)号：US06723047B1
公开(公告)日：2004-04-20
申请号：US10009187
申请日：2001-12-07
IPC分类号： A61B500
CPC分类号： G06F3/015 , A61B5/486 , A63F2250/26 , Y10S128/905
摘要： It has long been unclear in what degree the brain should be activated and how much the blood volume should be varied for controlling a signal by measuring the concentration of metabolic substance in the tissue or change of concentration thereof using the light and by using the result of measurement. The present invention provides an optical measuring system which can present the concentration of metabolic substance in the tissue which may be detected with a subject by itself or the target value of change of the concentration. Thereby, it is now possible for the subject by itself to more easily detect and control the concentration of metabolic substance in the tissue or change of concentration thereof. As a result, cerebral information can be extracted in direct to realize various applications such as control of the game machines and welfare facilities.
摘要翻译： 长期以来，不清楚大脑应该被激活的程度以及通过使用光测量组织中代谢物质的浓度或其浓度的变化来控制信号来改变血容量，并且通过使用 测量。 本发明提供一种光学测量系统，其可以呈现组织中代谢物质的浓度，其可以由受试者自身检测或目标浓度变化值。 因此，现在可以使受试者本身更容易地检测和控制组织中代谢物质的浓度或其浓度的变化。 因此，可以直接提取脑信息，实现游戏机和福利设施的控制等各种应用。
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