公开(公告)号：US20070050957A1

公开(公告)日：2007-03-08

申请号：US11217442

申请日：2005-09-02

申请人： Kevin Brown

发明人： Kevin Brown

IPC分类号： F16B45/02

CPC分类号： F16B45/02 ,  Y10T24/4534

摘要： A snap hook having a hook shank and a gate keeper. The hook shank includes a main body and a hook member that has a hook bowl and a hook bill. The hook bill and the main body define a gateway opening therebetween. The gate keeper has an outer face and has an open position and a closed position. The hook bill ends in a spigot and the gate keeper further includes a generally correspondingly dimensioned receiver such that when the gate keeper is in its closed position the spigot is at least partially received within the receiver, with the spigot and receiver thereby resisting movement of the gate keeper when a force directed in a generally inward direction toward the main body is applied to the outer face of the gate keeper.

摘要翻译： 具有钩柄和闸门的钩钩。 钩柄包括主体和具有钩碗和钩纸的钩构件。 钩纸和主体在其间限定了一个通道开口。 闸门具有外表面并具有打开位置和关闭位置。 挂钩纸币以插头结束，并且门保持器还包括大致相应尺寸的接收器，使得当门保持器处于其闭合位置时，插口至少部分地被容纳在接收器内，由此插销和接收器从而抵抗 当向大致向内的方向朝向主体施加的力被施加到闸门保持器的外表面时，闸门保持器。

公开(公告)号：US20060008469A1

公开(公告)日：2006-01-12

申请号：US10887770

申请日：2004-07-09

申请人： Kevin Brown ,  Ning Zhi ,  Peter Tijssen ,  Zoltan Zadori

发明人： Kevin Brown ,  Ning Zhi ,  Peter Tijssen ,  Zoltan Zadori

IPC分类号： C12Q1/68 ,  A61K39/12 ,  C12N7/02

CPC分类号： C12Q1/701 ,  C12N7/00 ,  C12N2750/14251

摘要： The invention relates to infectious clones of parvovirus B19, methods of cloning infectious B19 clones, and methods of cloning viral genomes that have secondary DNA structures that are unstable in bacterial cells. A B19 infectious clone and methods of producing B19 infectious clones are useful for producing infectious virus. Infectious virus is useful for identifying and developing therapeutically effective compositions for treatment and/or prevention of human parvovirus B19 infections.

公开(公告)号：US20050216301A1

公开(公告)日：2005-09-29

申请号：US11080254

申请日：2005-03-14

申请人： Kevin Brown

发明人： Kevin Brown

IPC分类号： G06Q10/00 ,  G06F17/60

CPC分类号： G06Q10/047 ,  G01C21/3423 ,  G01C21/343 ,  G06Q10/02 ,  G06Q10/025

摘要： An activity-based itinerary planning tool permits a trip planner to incrementally build and itinerary starting at a selected entry point and adding activities in a step-by-step manner, by taking into account commute times for different types of transportation and entry/exit conditions for particular activities/facilities in order to present the user with lists of all activities/facilities that can be reached from the entry point or from already selected activities/facilities.

摘要翻译： 基于活动的行程规划工具允许旅行计划员从选定的入口点开始逐步构建和行进，并以逐步的方式添加活动，考虑到不同类型运输和进出口条件的通勤时间 对于特定的活动/设施，以向用户提供从入境点或已经选定的活动/设施可以达到的所有活动/设施的清单。

公开(公告)号：US20050089141A1

公开(公告)日：2005-04-28

申请号：US10971298

申请日：2004-10-21

申请人： Kevin Brown

发明人： Kevin Brown

IPC分类号： A61N5/10

CPC分类号： A61N5/1081 ,  A61N5/10 ,  A61N5/1042 ,  A61N5/1082

摘要： A radiation therapy/surgery device optimised to meet the needs of the Neurosurgeon is provided, i.e. one for the treatment of tumours in the brain. It combines the qualities of a good penumbra and accuracy, simple prescription and operation, together with high reliability and minimal technical support. The device comprises a rotateable support, on which is provided a mount extending from the support out of the plane of the circle, and a radiation source attached to the mount via a pivot, the pivot having an axis which passes through the axis of rotation of the support, the radiation source being aligned so as to produce a beam which passes through the co-incidence of the rotation axis and the pivot. It will generally be easier to engineer the apparatus if the rotateable support is planar, and more convenient if the rotateable support is disposed in an upright position. The rotation of the rotateable support will be eased if this part of the apparatus is circular. A particularly preferred orientation is one in which the radiation source is spaced from the rotateable support, to allow it to pivot without fouling the latter. It is thus preferred that the mount extends transverse to the support. In this way, the pivot axis is spaced from the rotateable support providing free space in which the radiation source can pivot. Another way of expressing this preference is to state that the pivot axis is located out of the plane of the rotateable support. To simplify the geometry of the device and the associated arithmetic, it is preferred both that the pivot axis is substantially perpendicular to the rotation axis, and that the beam direction is perpendicular to the pivot axis. It is preferred that the radiation source is a linear accelerator. The output of the radiation source is preferably collimated to conform to the shape of the area to be treated.

摘要翻译： 提供了优化以满足神经外科医生需求的放射治疗/手术装置，即用于治疗脑中肿瘤的放射治疗/手术装置。 它结合了良好的半暗带的质量和准确性，简单的处方和操作，以及高可靠性和最小的技术支持。 该装置包括可旋转的支撑件，其上设置有从支撑件延伸出圆的平面的安装座，以及通过枢轴连接到安装座的辐射源，该枢轴具有穿过轴的旋转轴线 支撑件，辐射源被对准以便产生通过旋转轴线和枢轴的共同入射的梁。 如果可旋转支撑件是平面的，通常更容易设计设备，并且如果可旋转支撑件设置在直立位置，则更方便。 如果设备的这部分是圆形的，则可旋转支撑件的旋转将被缓解。 特别优选的方向是其中辐射源与可旋转支撑件间隔开的方向，以允许其枢转而不使其污染。 因此，优选地，安装件横向于支撑件延伸。 以这种方式，枢转轴线与可旋转支撑件间隔开，从而提供辐射源能在其中枢转的自由空间。 表示这种偏好的另一种方式是说明枢转轴线位于可旋转支撑平面之外。 为了简化装置的几何形状和相关联的运算，优选地，枢转轴线基本上垂直于旋转轴线，并且梁方向垂直于枢转轴线。 优选的是，辐射源是线性加速器。 辐射源的输出优选地被准直以符合待处理区域的形状。

公开(公告)号：US20050030808A1

公开(公告)日：2005-02-10

申请号：US10882389

申请日：2004-07-02

申请人： Kevin Brown ,  Richard Thousand ,  John Creigh

发明人： Kevin Brown ,  Richard Thousand ,  John Creigh

IPC分类号： G11C7/00 ,  H04L12/12 ,  H04L12/40 ,  H04L12/64

CPC分类号： H04L12/12 ,  H04L12/40052 ,  H04L12/40097 ,  Y02D50/20 ,  Y02D50/40 ,  Y02D50/42

摘要： The present invention provides a way of placing a physical layer device into a standby mode. After a link is established between multiple devices, a determination is made whether the device has data to transmit or whether a standby request was received from a link partner. If a standby request was received or the device has no data to transmit, standby mode is entered. In standby mode, unneeded circuitry is powered down. A transmitter in a channel and a receive path in a separate channel remain powered. While operating in standby mode, the PHY layer continuously transmits a standby code on the one or more channels that are not powered down. Standby mode is discontinued when a transceiver has data to transmit or when energy is detected on the powered down channels. Standby mode is also discontinued when no standby code is received, indicating a disconnect between devices.

摘要翻译： 本发明提供了将物理层设备置于待机模式的方式。 在多个设备之间建立链路之后，确定设备是否具有要发送的数据，还是从链路伙伴接收到待机请求。 如果接收到待机请求或设备没有要发送的数据，则进入待机模式。 在待机模式下，不需要的电路掉电。 信道中的发射机和单独信道中的接收路径保持供电。 在待机模式下工作时，PHY层在一个或多个未断电的通道上连续发送待机代码。 当收发器具有要传输的数据或在掉电通道上检测到能量时，待机模式将停止。 当没有接收到待机代码时，待机模式也被停止，指示设备之间断开连接。

公开(公告)号：US6071566A

公开(公告)日：2000-06-06

申请号：US245600

申请日：1999-02-05

申请人： Kevin Brown ,  Nie Tang ,  Jun Song

发明人： Kevin Brown ,  Nie Tang ,  Jun Song

IPC分类号： B05D7/16 ,  C09D4/00 ,  C09D183/14 ,  C23C22/53 ,  C23C22/68 ,  B05D7/14

CPC分类号： C23C22/68 ,  B05D7/16 ,  C09D183/14 ,  C09D4/00 ,  C23C22/53 ,  B05D2350/65 ,  C23C2222/20

摘要： The present invention relates to a method of treating a metal substrate to provide permanent corrosion resistance. The method comprises applying a solution containing one or more vinyl silanes in admixture with one or more multi-silyl-functional silanes to a metal substrate in order to form a coating. The method is particularly suitable for use on zinc coated surfaces.

摘要翻译： 本发明涉及一种处理金属基材以提供永久耐腐蚀性的方法。 该方法包括将含有一种或多种乙烯基硅烷的溶液与一种或多种多甲硅烷基官能的硅烷混合加入到金属底物中以形成涂层。 该方法特别适用于镀锌表面。

公开(公告)号：US09336612B2

公开(公告)日：2016-05-10

申请号：US14006710

申请日：2012-03-16

申请人： Kevin Brown

发明人： Kevin Brown

IPC分类号： G06K9/40 ,  G06T11/00 ,  G06T5/50

CPC分类号： G06T11/003 ,  G06T5/50 ,  G06T11/008

摘要： A method for processing one or more reconstructed images includes receiving a first reconstructed image having a first image resolution and receiving a second reconstructed image having a second image resolution. The first resolution is greater than the second resolution. The method further includes generating a contrast-dependent resolution image by combining the first and second reconstructed images single image so that the first reconstructed image contributes to a greater degree to the contrast-dependent resolution image for higher contrasts regions of the images and the second reconstructed image contributes to a greater degree to the contrast-dependent resolution image for lower contrasts regions of the images.

摘要翻译： 一种用于处理一个或多个重建图像的方法包括接收具有第一图像分辨率的第一重建图像和接收具有第二图像分辨率的第二重建图像。 第一项决议大于第二项决议。 该方法还包括通过组合第一和第二重建图像单个图像来生成对比度依赖的分辨率图像，使得第一重建图像对于对比度依赖的分辨率图像有更大的贡献，用于图像的较高对比度区域和第二重构图像 图像对于对比度依赖的分辨率图像有较大的影响，用于图像的较低对比度区域。

公开(公告)号：US08932679B2

公开(公告)日：2015-01-13

申请号：US12958009

申请日：2010-12-01

申请人： Manfred Walter ,  Axel Schöne ,  Christian Jung ,  Kevin Brown ,  Thomas Kolberg ,  Norbert Kliehm

发明人： Manfred Walter ,  Axel Schöne ,  Christian Jung ,  Kevin Brown ,  Thomas Kolberg ,  Norbert Kliehm

IPC分类号： B05D3/00 ,  C09D4/00 ,  C09D5/08 ,  C23C22/50 ,  C23C22/53 ,  C23C22/60 ,  C23C22/68 ,  C23C22/74 ,  C23C22/83

CPC分类号： C09D5/08 ,  C08K3/36 ,  C08K5/0091 ,  C08K5/5435 ,  C09D4/00 ,  C09D7/61 ,  C09D7/63 ,  C09D133/02 ,  C09D133/08 ,  C09D175/06 ,  C23C22/48 ,  C23C22/50 ,  C23C22/53 ,  C23C22/60 ,  C23C22/68 ,  C23C22/74 ,  C23C22/82 ,  C23C22/83 ,  C23C2222/20 ,  Y02T50/67 ,  Y10T428/31663 ,  C08G77/04 ,  C08G77/26

摘要： A method for coating a metallic surface with an aqueous composition for pretreating before applying another coating or for treating said metallic surfaces. The method is characterized in that the composition contains, in addition to water; a) at least one hydrolyzable or at least partially hydrolyzed fluorine-free silane, and; b) at least one hydrolyzable or at least partially hydrolyzed fluorine-containing silane. The invention also relates to corresponding compositions.

摘要翻译： 一种用于在施加另一涂层或用于处理所述金属表面之前用用于预处理的水性组合物涂覆金属表面的方法。 该方法的特征在于除了水之外，组合物还含有 a）至少一种可水解或至少部分水解的无氟硅烷，和 b）至少一种可水解或至少部分水解的含氟硅烷。 本发明还涉及相应的组合物。

公开(公告)号：US08731257B2

公开(公告)日：2014-05-20

申请号：US13132805

申请日：2008-12-08

申请人： Kevin Brown

发明人： Kevin Brown

IPC分类号： G06K9/00

CPC分类号： A61B6/032 ,  A61B5/113

摘要： The present invention therefore provides a method for the analysis of radiographic images, comprising the steps of acquiring a plurality of projection images of a patient, acquiring a surrogate signal indicative of the location of a target structure in the patient, reconstructing a plurality of volumetric images of the patient from the projection images, each volumetric image being reconstructed from projection images having a like breathing phase, identifying the position of the target structure such as a tumor in each volumetric image, associating a surrogate signal with each of the projection images, and determining a relationship between the surrogate signal and the position of the target structure. Multiple projection images having a like breathing phase can be grouped for reconstruction, to provide sufficient numbers for reconstruction. The analysis of the multiple values of the surrogate associated with each breathing phase can be used to determine the mean surrogate value and its variation. Multiple values of the surrogate signal associated with the same nominal breathing phase can be used to determine a mean value of the surrogate signal for the target position associated with that phase and a variation of the value of the surrogate signal for the target position associated with that phase. The breathing phase of specific projection images can be obtained by analysis of one or more features in the images, such as the method we described in U.S. Pat. No. 7,356,112, or otherwise.

摘要翻译： 因此，本发明提供了一种用于分析放射线图像的方法，包括以下步骤：获取患者的多个投影图像，获取指示患者中目标结构的位置的替代信号，重建多个体积图像 从投影图像的患者的每个体积图像中，从具有相似呼吸相位的投影图像重建每个体积图像，识别每个体积图像中的诸如肿瘤的目标结构的位置，将替代信号与每个投影图像相关联，以及 确定替代信号与目标结构的位置之间的关系。 具有类似呼吸相位的多个投影图像可以被分组以进行重建，以提供足够数量的重建。 可以使用与每个呼吸阶段相关联的替代物的多个值的分析来确定平均替代值及其变化。 可以使用与相同标称呼吸相位相关联的替代信号的多个值来确定与该相位相关联的目标位置的替代信号的平均值，以及与该相位相关联的目标位置的替代信号的值的变化 相。 特定投影图像的呼吸阶段可以通过分析图像中的一个或多个特征来获得，例如我们在美国专利中描述的方法。 7,356,112，否则。

公开(公告)号：US20140107390A1

公开(公告)日：2014-04-17

申请号：US13650910

申请日：2012-10-12

申请人： Kevin Brown ,  Tarun K. Podder ,  Yan Yu

发明人： Kevin Brown ,  Tarun K. Podder ,  Yan Yu

IPC分类号： A61N5/10 ,  G06F19/00

CPC分类号： A61N5/107 ,  A61N5/1045 ,  A61N5/1067 ,  A61N5/1068 ,  A61N2005/1057

摘要： Methods and systems of operating a support structure and beam shaping mechanism in a manner that compensates for motion patterns exhibited by a patient, promotes comfort of the patient, and optimizes accuracy of delivery of radiotherapy to a targeted location within the patient. The support structure can be a treatment table or couch and the beam shaping mechanism can be a multi-leaf collimator (MLC), and/or an MLC-bank/-carriage. The control system can utilize algorithms for predicting tumor motion and loading condition on the table/couch during radiation therapy.

摘要翻译： 以补偿患者展示的运动模式的方式操作支撑结构和束形成机构的方法和系统，促进患者的舒适度，并且优化将放射治疗递送到患者内的目标位置的准确性。 支撑结构可以是治疗台或沙发，并且束整形机构可以是多叶准直器（MLC）和/或MLC库/流动。 控制系统可以利用算法来预测放射治疗期间的桌子/沙发上的肿瘤运动和负荷状况。