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205 条记录 (耗时 0.074 秒)

    COMBINED SENSOR AND INFUSION SETS
    81.
    发明申请
    COMBINED SENSOR AND INFUSION SETS 审中-公开
    组合传感器和输液器

    公开(公告)号：US20120046533A1

    公开(公告)日：2012-02-23

    申请号：US13008723

    申请日：2011-01-18

    申请人： Gayane R. Voskanyan ,  Katherine T. Wolfe ,  Brian Chung ,  Eric Allan Larson ,  Jose J. Ruelas ,  Rajiv Shah

    发明人： Gayane R. Voskanyan ,  Katherine T. Wolfe ,  Brian Chung ,  Eric Allan Larson ,  Jose J. Ruelas ,  Rajiv Shah

    IPC分类号： A61B5/145

    CPC分类号： A61B5/14532 ,  A61B5/0031 ,  A61B5/14865 ,  A61B5/4839 ,  A61B5/6849 ,  A61M5/158

    摘要： Embodiments of the invention provide a dual insertion set for supplying a fluid to the body of a patient and for monitoring a body characteristic of the patient. Typical embodiments of the invention include a base, an infusion portion coupled to a first piercing member and a sensor portion coupled to a second piercing member. The infusion portion includes a cannula coupled to the piercing member for supplying a fluid to a placement site. The sensor portion includes a sensor coupled to and extending from the base having at least one sensor electrode formed on a substrate and is coupled to the piercing member in a manner that allows the sensor to be inserted at the placement site. The base is arranged to secure the dual insertion set to the skin of a patient. Typically the infusion portion and sensor portion piercing members are arranged such that when they are operatively coupled to the base, they are disposed in a spatial orientation designed to inhibit sensor interference that may be caused by compounds present in fluids infused through the cannula.

    摘要翻译： 本发明的实施例提供了一种用于向患者的身体供应流体并用于监测患者的身体特征的双重插入组。 本发明的典型实施例包括底座，联接到第一刺穿构件的输注部分和联接到第二穿刺构件的传感器部分。 输注部分包括联接到穿刺构件的套管，用于将流体供应到放置位置。 所述传感器部分包括传感器，所述传感器耦合到所述底座并且具有至少一个传感器电极并从所述底座延伸并且以允许所述传感器插入所述放置位置的方式联接到所述穿孔构件。 基座设置成将双重插入件固定到患者的皮肤上。 通常，输注部分和传感器部分刺穿构件被布置成使得当它们可操作地联接到基部时，它们被设置成空间方向，其设计成阻止可能由存在于通过插管注入的流体中的化合物引起的传感器干扰。

    MULTILUMEN CATHETER
    84.
    发明申请
    MULTILUMEN CATHETER 审中-公开
    多层导管

    公开(公告)号：US20110046457A1

    公开(公告)日：2011-02-24

    申请号：US12917162

    申请日：2010-11-01

    申请人： Rebecca Gottlieb ,  Rajiv Shah ,  Mary M. Morris ,  Victor Giron ,  Michael E. Miller ,  Bradley J. Enegren

    发明人： Rebecca Gottlieb ,  Rajiv Shah ,  Mary M. Morris ,  Victor Giron ,  Michael E. Miller ,  Bradley J. Enegren

    IPC分类号： A61B5/145 ,  B23P17/04

    CPC分类号： A61M25/0032 ,  A61B5/028 ,  A61B5/14532 ,  A61B5/1486 ,  A61B5/415 ,  A61M5/14244 ,  A61M5/1723 ,  A61M25/0017 ,  A61M25/0023 ,  A61M2025/0003 ,  A61M2025/0046 ,  A61M2230/201 ,  Y10T29/49826

    摘要： A multilumen catheter having tubings extending into lumens within the catheter. The lumens may be used for blood, drugs or other medicants. The lumens may also be used for sensors. The junction element, external to the patient, connects the tubings to the lumens. The tubings, also external to the patient, connect to infusion members, to which one or more infusion systems may be connected to deliver blood, drugs and other medicants to the patient. A sensor having a sensing element may extend through the sensor lumen and be positioned internal to the patient for physiological parameter sensing. An external portion of the sensor may be connected to associated electronics to provide automatic monitoring of the physiological parameters and automatic delivery and control of the infusants. Also, a central line catheter for delivering fluids directly into a main artery or vein near the heart, which contains a first lumen to deliver a fluid through the central line catheter and a second lumen containing a sensor capable indicating a characteristic level in blood. The first lumen delivers the fluid downstream of the sensor to prevent any interference between the fluid delivery and the sensor readings. In other versions, the central line catheter can have additional lumens for additional purposes. In addition, the central line catheter can further include a flush sleeve to remove debris around the sensor.

    摘要翻译： 一种多管导管，其具有延伸到导管内腔内的管道。 流明可用于血液，药物或其他药物。 流明也可用于传感器。 患者外部的连接元件将管道连接到管腔。 也在患者外部的管连接到输注构件，一个或多个输注系统可以连接到输注构件，以向患者输送血液，药物和其他药剂。 具有感测元件的传感器可以延伸穿过传感器内腔并且位于患者的内部以用于生理参数感测。 传感器的外部部分可以连接到相关联的电子设备，以提供对生理参数的自动监测以及对输入的自动传送和控制。 另外，一种用于将流体直接输送到心脏附近的主动脉或静脉的中心线导管，其包含用于通过中心线导管输送流体的第一内腔和包含能够指示血液中的特征水平的传感器的第二腔。 第一个内腔在传感器的下游传送流体，以防止流体输送和传感器读数之间的任何干扰。 在其他版本中，中心线导管可以具有另外的流明用于其他目的。 此外，中心线导管还可以包括冲洗套筒以去除传感器周围的碎屑。

    Biosensors and methods for making and using them
    89.
    发明授权
    Biosensors and methods for making and using them 有权
    生物传感器和制造和使用它们的方法

    公开(公告)号：US07813780B2

    公开(公告)日：2010-10-12

    申请号：US11301512

    申请日：2005-12-13

    申请人： Rajiv Shah ,  Gopikrishnan Soundararajan ,  Rebecca K. Gottlieb ,  Udo Hoss ,  Eric A. Grovender ,  Shaun M. Pendo

    发明人： Rajiv Shah ,  Gopikrishnan Soundararajan ,  Rebecca K. Gottlieb ,  Udo Hoss ,  Eric A. Grovender ,  Shaun M. Pendo

    IPC分类号： A61B5/05

    CPC分类号： C12Q1/006

    摘要： Embodiments of the invention provide analyte sensors having optimized permselective membranes and methods for making and using such sensors. Embodiments of the invention also provide analyte sensors such as those having porous matrices coated with an analyte sensing composition and methods for making and using such sensors. Illustrative embodiments include electrochemical glucose sensors having glucose oxidase coatings.

    摘要翻译： 本发明的实施例提供具有优化的选择渗透膜的分析物传感器以及用于制造和使用这种传感器的方法。 本发明的实施例还提供分析物传感器，例如具有涂覆有分析物感测组合物的多孔基质的分析物传感器以及用于制造和使用这种传感器的 示例性实施方案包括具有葡萄糖氧化酶涂层的电化学葡萄糖传感器。

    Multilayer substrate
    90.
    发明授权
    Multilayer substrate 有权
    多层基板

    公开(公告)号：US07781328B2

    公开(公告)日：2010-08-24

    申请号：US11868898

    申请日：2007-10-08

    申请人： Rajiv Shah ,  Shaun Pendo ,  Edward B. Babiricki

    发明人： Rajiv Shah ,  Shaun Pendo ,  Edward B. Babiricki

    IPC分类号： H01L21/4763

    CPC分类号： H01L21/4857 ,  H01L2924/0002 ,  H05K1/092 ,  H05K3/4061 ,  H05K3/4647 ,  H05K3/4667 ,  H05K3/467 ,  H05K2201/0179 ,  H05K2203/0278 ,  H01L2924/00

    摘要： A multilayer substrate device formed from a base substrate and alternating metalization layers and dielectric layers. Each layer is formed without firing. Vias may extend through one of the dielectric layers such that two metalization layers surrounding the dielectric layers make contact with each other. The vias may be formed by placing pillars on top of a metalization layer, forming a dielectric layer on top of the metalization layer and surrounding the pillars, and removing the pillars. Dielectric layers may be followed by other dielectric layers and metalization layers may be followed by other metalization layers. Vias in the substrate may be filled by forming an assembly around the substrate, the assembly including printing sheets containing a conductive ink and pressure plates for applying pressure. A vacuum may be applied to remove air in the ink. Pressure may then be applied to the printing sheets through the pressure plates. The conductive ink in the printing sheets is pushed through the vias when pressure is applied by the pressure plates.

    摘要翻译： 由基底基板和交替的金属化层和电介质层形成的多层衬底器件。 每层形成而不烧制。 通孔可以延伸穿过介电层之一，使得围绕电介质层的两个金属化层彼此接触。 可以通过将金属化层顶部放置柱子形成通孔，在金属化层的顶部上形成电介质层并围绕柱子，并移除支柱。 电介质层之后可以是其它电介质层，金属化层之后可以是其它金属化层。 可以通过在基板周围形成组件来填充基板中的通孔，该组件包括含有导电油墨的印刷纸和用于施加压力的压力板。 可以施加真空以除去油墨中的空气。 然后可以通过压力板将压力施加到印刷纸上。 当通过压力板施加压力时，打印纸中的导电油墨被推过通孔。