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    Radioactive therapeutic seed having selective marker configuration
    81.
    发明授权
    Radioactive therapeutic seed having selective marker configuration 失效
    具有选择标记物配置的放射性治疗种子

    公开(公告)号：US06712752B2

    公开(公告)日：2004-03-30

    申请号：US10295658

    申请日：2002-11-15

    申请人： Charles R. Slater ,  Thomas O. Bales

    发明人： Charles R. Slater ,  Thomas O. Bales

    IPC分类号： A61N500

    CPC分类号： A61N5/1027 ,  A61B90/39 ,  A61B2090/3954 ,  A61N2005/1024

    摘要： Radioactive therapeutic seeds include a carrier structure bearing a radioactive isotope and a radiopaque marker. According to several embodiments, the seeds include a central plug provided with an axial marker and a relatively transverse bore extending through the marker. A second marker may be positioned in the bore, thereby distinguishing a seed provided with the second marker relative to a seed not provided with the second marker. According to another embodiment, the isotope is deposited on the outer surface of a hollow radiolucent tube. A biologically-compatible, radiolucent, surface-sealing layer seals the external surface of the tube. A radiopaque marker wire of selected length is positioned in the hollow of the tube. Seeds may be distinguished from one another by providing seeds with marker wires of different lengths. According to other embodiments, the seed includes a cylindrical outer member, and an inner member provided within the outer member and having two large diameter portions and a relatively smaller diameter portion therebetween. A marker is disposed within the inner member, and a radioactive isotope is carried on the inner member. The marker may be drilled to a smaller size. Each embodiment permits at least two groups of seeds to be distinguished from one another by the use of differing marker configurations.

    摘要翻译： 放射治疗种子包括具有放射性同位素和不透射线标记的载体结构。 根据几个实施例，种子包括设置有轴向标记的中心塞和延伸穿过标记的相对横向的孔。 可以将第二标记物定位在孔中，从而与提供有第二标记的种子相对于未设置第二标记的种子进行区分。 根据另一个实施方案，同位素沉积在中空的射线可透管的外表面上。 生物相容的射线可透过的表面密封层密封管的外表面。 所选长度的不透射线标记线位于管的中空中。 通过为种子提供不同长度的标记线，种子可以彼此区分。 根据其他实施例，种子包括圆柱形外部构件和设置在外部构件内部并具有两个大直径部分和其间相对较小直径部分的内部构件。 标记物设置在内部构件内，并且放射性同位素被承载在内部构件上。 标记可以钻到较小的尺寸。 每个实施例允许通过使用不同的标记物构造将至少两组种子彼此区分开。

    Bipolar endoscopic surgical scissor blades and instrument incorporating the same
    82.
    发明授权
    Bipolar endoscopic surgical scissor blades and instrument incorporating the same 失效
    双极内窥镜手术剪刀刀片和并入其中的仪器

    公开(公告)号：US06447511B1

    公开(公告)日：2002-09-10

    申请号：US08806386

    申请日：1997-02-27

    申请人： Charles R. Slater

    发明人： Charles R. Slater

    IPC分类号： A61B1818

    CPC分类号： A61B18/14 ,  A61B18/1445 ,  A61B18/1815 ,  A61B2018/00083 ,  A61B2018/00107 ,  A61B2018/00178 ,  A61B2018/126 ,  A61B2018/1412 ,  A61B2018/146 ,  A61B2018/1861

    摘要： Endoscopic bipolar scissor blades are formed in a laminate assembly of an electrically conductive electrode, an electrically insulating material, and a metal shearing surface which is electrically insulated and physically spaced from the electrode by the insulating material which is disposed therebetween. In one embodiment, the electrode is a metal blade, while the insulating material is a ceramic which is fixed to the metal blade, and the metal shearing surface which also provides the cutting edge is of a metal material which is fixed to the ceramic. In a second embodiment, the insulating material is a molded ceramic blade, with the electrode and the metal shearing surface layer metalized or otherwise fixed to the ceramic blade. In a third embodiment, the electrode is metalized on a thin layer insulating material which is fixed onto a metallic blade. In a fourth embodiment, metallic shearing and electrode layers are laminated to opposite sides of a fiberglass material. In all embodiments, the metal cutting edges and surfaces are insulated from the electrodes, and no short circuit can form between the electrodes even though the cutting edges and shearing surfaces are metal.

    摘要翻译： 内窥镜双极剪刀刀片形成在导电电极，电绝缘材料和金属剪切表面的层压组件中，电绝缘材料和金属剪切表面通过设置在它们之间的绝缘材料与电极电绝缘和物理间隔开。 在一个实施例中，电极是金属刀片，而绝缘材料是固定到金属刀片上的陶瓷，并且还提供切削刃的金属剪切表面是固定在陶瓷上的金属材料。 在第二实施例中，绝缘材料是模制陶瓷刀片，其中电极和金属剪切表面层被金属化或以其他方式固定到陶瓷刀片。 在第三实施例中，电极被金属化在固定在金属刀片上的薄层绝缘材料上。 在第四实施例中，将金属剪切和电极层层压到玻璃纤维材料的相对侧上。 在所有实施例中，金属切割边缘和表面与电极绝缘，并且即使切割边缘和剪切表面是金属，也不会在电极之间形成短路。

    Endoscopic bipolar multiple sample bioptome
    85.
    发明授权
    Endoscopic bipolar multiple sample bioptome 失效
    内窥镜双极多重样本bioptome

    公开(公告)号：US5683388A

    公开(公告)日：1997-11-04

    申请号：US584801

    申请日：1996-01-11

    申请人： Charles R. Slater

    发明人： Charles R. Slater

    IPC分类号： A61B10/06 ,  A61B1/00 ,  A61B10/00 ,  A61B10/02 ,  A61B18/12 ,  A61B18/14 ,  A61B17/39

    CPC分类号： A61B10/06 ,  A61B18/1442 ,  A61B10/02 ,  A61B18/1492 ,  A61B2010/0225 ,  A61B2018/126

    摘要： An endoscopic bipolar multiple sample bioptome includes a relatively long conductive flexible member having a lumen with an axially displaceable conductive wire extending therethrough and covered with an electrically insulating sheath. The proximal ends of the flexible member and wire are coupled to a manual actuation device for axially displacing one of the flexible member and wire relative to the other and the manual actuation device is provided with bipolar electrical couplings for electrically coupling one pole of a current source to the flexible member and the other pole of the current source to the wire. The distal end of the flexible member is mechanically and electrically coupled to a partially conductive cylinder having a distal edge and the distal end of the wire is mechanically and electrically coupled to the jaw assembly. The jaw assembly includes a pair of opposed toothed jaw cups each of which is coupled by a narrow resilient arm to a base member. The base member is mounted inside the cylinder and axial movement of the base member relative to the cylinder draws the necks of the jaws into the cylinder to bring the jaw cups together in a biting action. The cylinder is substantially non-conductive with portions of its exterior being conductive. Cautery current flows between the jaw assembly and the conductive portion(s) of the cylinder by way of tissue which is being cauterized.

    摘要翻译： 内窥镜双极多重样本生物切割器包括相对较长的导电柔性构件，其具有内腔，其具有延伸穿过其中且被电绝缘护套覆盖的可轴向移位的导电线。 柔性构件和线的近端联接到手动致动装置，用于相对于另一个轴向移动柔性构件和线中的一个，并且手动致动装置设置有用于电耦合电流源的一极的双极电耦合 将电流源的柔性构件和另一极连接到导线。 柔性构件的远端机械地和电耦合到具有远端边缘的部分导电圆柱体，并且线的远端机械地和电耦合到钳口组件。 钳口组件包括一对相对的齿形钳口杯，每个钳口杯均由狭窄的弹性臂与底座构件联接。 底座部件安装在缸体内，基座部件相对于气缸的轴向运动将颚部的颈部拉入气缸，以使咬合杯以咬合动作。 气缸基本上不导电，其外部的部分是导电的。 烧灼电流通过被烧灼的组织在夹钳组件和气缸的导电部分之间流动。

    Flexible tube having a tapered diameter portion for use with endoscopic irrigation instruments
    86.
    发明授权
    Flexible tube having a tapered diameter portion for use with endoscopic irrigation instruments 失效
    柔性管具有用于内窥镜灌洗仪器的锥形直径部分

    公开(公告)号：US5549547A

    公开(公告)日：1996-08-27

    申请号：US248523

    申请日：1994-05-24

    申请人： Herbert Cohen ,  Matthew S. Solar ,  Charles R. Slater

    发明人： Herbert Cohen ,  Matthew S. Solar ,  Charles R. Slater

    IPC分类号： A61B17/32 ,  A61B18/00 ,  A61B18/14 ,  A61M1/00 ,  A61M3/02 ,  A61M5/14

    CPC分类号： A61B17/3203 ,  A61B18/1442 ,  A61B18/1482 ,  A61M1/0043 ,  A61M1/0045 ,  A61M1/0064 ,  A61M3/0233 ,  A61M5/1418 ,  A61B10/02 ,  A61B18/148 ,  A61B2017/32113 ,  A61B2018/00958 ,  A61M1/0062 ,  A61M2205/6081

    摘要： An endoscopic irrigation instrument includes a fluid chamber, a cannula coupled to a distal end of the fluid chamber, a tapered irrigation tube which couples at its proximal end to a fluid source and which couples at its distal end to an irrigation port of the fluid chamber, and a pinch valve which controls the flow of fluid from the irrigation source to the fluid chamber and hence through the cannula to the surgical site. The tapered irrigation tube is arranged so that it has a first relatively larger constant inner diameter and relatively larger wall thickness on its proximal end until it tapers down in both inner diameter and wall thickness at a location slightly proximal the pinch valve. By the time the tapered irrigation tube passes the pinch valve in the endoscopic instrument, the tapered irrigation tube is at a second relatively smaller constant inner diameter and a relatively smaller wall thickness. The tapered irrigation tube thus enables greater fluid flow, pinch valve control at the thin distal end, and tube reliability at both high and low fluid pressures.

    摘要翻译： 内窥镜灌注仪器包括流体室，连接到流体室的远端的套管，锥形冲洗管，其近端连接到流体源并且在其远端处连接到流体室的冲洗口 以及夹管阀，其控制从冲洗源到流体室的流体流动，并且因此通过套管到手术部位。 锥形灌溉管被布置成使得其在其近端具有第一相对较大的恒定内径和相对较大的壁厚，直到在稍微靠近夹紧阀的位置处内径和壁厚均匀下降。 当锥形灌洗管通过内窥镜仪器中的夹紧阀时，锥形灌洗管处于第二相对较小的恒定内径和相对较小的壁厚。 因此，锥形灌溉管能够实现更大的流体流动，在薄的远端处的夹管阀控制，以及在高和低流体压力下的管可靠性。

    Temperature cycle counter
    88.
    发明授权
    Temperature cycle counter 失效
    温度循环计数器

    公开(公告)号：US5452335A

    公开(公告)日：1995-09-19

    申请号：US999228

    申请日：1992-12-31

    申请人： Charles R. Slater ,  Thomas O. Bales ,  Jurgen A. Kortenbach ,  George Nunez ,  David Turkel ,  David P. Gordon

    发明人： Charles R. Slater ,  Thomas O. Bales ,  Jurgen A. Kortenbach ,  George Nunez ,  David Turkel ,  David P. Gordon

    IPC分类号： A61B1/00 ,  A61B17/00 ,  A61B19/00 ,  G06M1/04 ,  G06M1/08 ,  G06M3/12 ,  G01K1/02

    CPC分类号： G06M1/083 ,  A61B17/00234 ,  G06M1/041 ,  G06M3/12 ,  A61B2090/0803 ,  A61B2560/0276

    摘要： An apparatus for counting the number of times a temperature cycle occurs includes an indicator having sequential indicia and a temperature responsive member for indicating a next one of the indicia. Mechanical, fluid mechanical and electronic versions of the invention are disclosed. In the mechanical version, the indicator can be a ratchet member having teeth, a pawl and a display surface containing indicia. A temperature responsive element such as a bimetallic member engages the teeth of the ratchet and advances the ratchet each time the apparatus is subjected to a preset temperature cycle. A housing with a window masks the display to indicate one of the indicia as advanced by the temperature responsive element. Preferred embodiments of the mechanical version include a ring-like ratchet member with interior teeth and an exterior display surface. The number of teeth is preferably one or more less than the number of indicia so that upon advancing the ratchet member to the last indicia, it can be advanced no further. The bimetallic element is mounted inside the ring and the housing covers the outer surface of the ring. A removable locking pin is provided to prevent movement of the ratchet member until activated.

    摘要翻译： 用于计算温度周期发生次数的装置包括具有顺序标记的指示器和用于指示下一个标记的温度响应构件。 公开了本发明的机械，流体机械和电子版本。 在机械版本中，指示器可以是具有齿，棘爪和包含标记的显示表面的棘轮构件。 诸如双金属构件的温度响应元件接合棘轮的齿并且每当设备经受预设温度循环时使棘轮前进。 具有窗口的壳体掩蔽显示器，以将温度响应元件中的一个标记指示为高级。 机械版本的优选实施例包括具有内齿和外部显示表面的环形棘轮构件。 优选地，齿数比标记的数量少一个或多个，从而在将棘轮构件推进到最后的标记之后，可以进一步推进。 双金属元件安装在环内，壳体覆盖环的外表面。 提供可拆卸的锁定销以防止棘轮构件的运动直到被激活。

    Endoscopic instrument with end effectors forming suction and/or irrigation lumens
    89.
    发明授权
    Endoscopic instrument with end effectors forming suction and/or irrigation lumens 失效
    具有末端执行器的内窥镜仪器形成吸入和/或冲洗腔

    公开(公告)号：US5417709A

    公开(公告)日：1995-05-23

    申请号：US226701

    申请日：1994-04-12

    申请人： Charles R. Slater

    发明人： Charles R. Slater

    IPC分类号： A61B17/28 ,  A61B17/30 ,  A61B17/32 ,  A61B18/14 ,  A61M1/00 ,  A61B17/42

    CPC分类号： A61B17/320016 ,  A61B18/1445 ,  A61B18/14 ,  A61B2017/2939 ,  A61B2017/306 ,  A61B2217/005 ,  A61B2217/007 ,  A61B2218/002 ,  A61B2218/007

    摘要： An endoscopic instrument with suction/irrigation end effectors includes a tube, a push rod which extends through the tube, an actuator engaging the tube and the push rod, and end effectors coupled to the tube and push rod, where the end effectors include or define a bore which acts as a lumen for suction/irrigation. A fluid conduit in the tube communicates with the bore in the end effectors and is coupled to a suction or irrigation source. In one embodiment, a pair of end effectors are each coupled to a separate irrigation/suction conduit which is fed through the tube. The proximal ends of the conduits are coupled to one or separate fluid couplings at the proximal end of the instrument for connection with suction/irrigation sources. In another embodiment, a stationary end effector is provided with a fluid bore which is coupled to a fluid conduit integral with the tube. In both of these embodiments, the fluid bore(s) terminate(s) in one or more openings on a surface of the end effector(s) so that suction/irrigation is provided on a surface of the end effector(s). In a third embodiment, the annulus between the push rod and the tube acts as a fluid conduit for suction/irrigation and each end effector is provided with a longitudinal surface groove which defines a lumen therebetween so that suction/irrigation may be performed when the end effectors are in the closed position.

    摘要翻译： 具有抽吸/冲洗端效应器的内窥镜仪器包括管，延伸穿过管的推杆，接合管和推杆的致动器以及联接到管和推杆的端部执行器，其中末端执行器包括或限定 一个作为吸入/灌溉管腔的孔。 管中的流体导管与末端执行器中的孔连通，并连接到抽吸或灌溉源。 在一个实施例中，一对末端执行器各自联接到单独的灌注/抽吸管道，其通过管进给。 导管的近端连接到仪器近端处的一个或单独的液体联接器，用于与抽吸/冲洗源连接。 在另一个实施例中，固定端部执行器设置有流体孔，该流体孔联接到与管一体的流体导管。 在这两个实施例中，流体孔在端部执行器的一个或多个表面上的一个或多个开口中终止，使得在末端执行器的表面上提供吸入/冲洗。 在第三实施例中，推杆和管之间的环形空间用作抽吸/冲洗的流体导管，并且每个端部执行器设置有纵向表面凹槽，其在其间限定内腔，使得当末端 效果器处于关闭位置。

    Laparoscopic hook scissors
    90.
    发明授权
    Laparoscopic hook scissors 失效
    腹腔镜钩剪刀

    公开(公告)号：US5203785A

    公开(公告)日：1993-04-20

    申请号：US780013

    申请日：1991-10-21

    申请人： Charles R. Slater

    发明人： Charles R. Slater

    IPC分类号： A61B17/3201 ,  A61B10/00 ,  A61B10/06 ,  A61B17/00 ,  A61B17/28 ,  A61B17/32 ,  A61B18/14 ,  A61B19/00

    CPC分类号： A61B10/06 ,  A61B17/29 ,  A61B17/320016 ,  A61B18/1445 ,  A61B17/3201 ,  A61B2017/00398 ,  A61B2017/0046 ,  A61B2017/0088 ,  A61B2017/292 ,  A61B2017/2926 ,  A61B2017/2931 ,  A61B2017/2939 ,  A61B2018/00077 ,  A61B2018/00083 ,  A61B2018/00107 ,  A61B2018/00148 ,  A61B2018/1412 ,  A61B2018/1415 ,  A61B2018/1455 ,  A61B2018/146 ,  A61B2018/1861 ,  A61B2090/064 ,  A61M2205/6081

    摘要： Hook scissors end effectors are provided for a laparoscopic instrument. The hook scissors end effectors generally comprise first and second blades, with at least one of the blades pivotally engaging the laparoscopic instrument. Each blade comprises an elongate straight blade member with an integral transverse hook element at the distal end of the blade member. The hook elements each extend towards the other blade member and each hook element is offset from its blade member so that a narrow recess is provided between opposing first and second hook members upon closing of the first and second blade members. The elongate straight blade members provide a straight scissors cutting action therebetween so that the contiguously adjacent portions of the blade members gradually come together in a continuous bearing contact to effect a cutting action. While the hook elements at the distal ends of the blades effectively provide a hook which contains the object to be severed, the distal portions of the blade members do not establish contact with each other until the cutting action reaches the distal portion of the scissors.

    摘要翻译： 提供钩剪刀末端效应器用于腹腔镜仪器。 钩剪刀端部执行器通常包括第一和第二叶片，其中至少一个叶片枢转地接合腹腔镜器械。 每个叶片包括细长的直叶片构件，其具有在叶片构件的远端处的整体横向钩构件。 钩元件各自朝向另一个叶片构件延伸，并且每个钩元件从其叶片构件偏移，使得在关闭第一和第二叶片构件时在相对的第一和第二钩构件之间设置窄的凹部。 细长的直叶片构件在它们之间提供直线剪刀切割动作，使得叶片构件的相邻的相邻部分以连续的轴承接触逐渐结合在一起以实现切割动作。 虽然叶片的远端处的钩元件有效地提供包含被切割物体的钩，但是在切割动作到达剪刀的远端部分之前，叶片构件的远端部分彼此不建立接触。