Drug complexes
    81.
    发明授权
    Drug complexes 失效
    药物复合物

    公开(公告)号:US06436912B1

    公开(公告)日:2002-08-20

    申请号:US09147342

    申请日:1999-03-25

    IPC分类号: A61K31715

    CPC分类号: A61K47/61

    摘要: A drug complex characterized in that a residue of a drug compound such as antineoplastic agents and a carboxy(C1-4)alkyldextran polyalcohol obtained by treating a dextran under conditions that enable substantially complete polyalcoholization are bound to each other by means of a spacer comprising an amino acid or a spacer comprising peptide-bonded 2 to 8 amino acids. Said complex is characterized-in that it has excellent selectivity to tumorous sites so as to exhibit high antineoplastic activity and also achieves reduced appearance of toxicity.

    摘要翻译: 一种药物复合物,其特征在于药物化合物如抗肿瘤剂和通过在能够基本上完全多元醇化的条件下处理葡聚糖而获得的羧基(C 1-4)烷基葡聚糖多元醇的残基通过包含 氨基酸或包含肽键合的2至8个氨基酸的间隔子。 所述复合物的特征在于其对肿瘤部位具有优异的选择性,从而表现出高的抗肿瘤活性,并且还实现了毒性的降低。

    Automatic brake booster
    82.
    发明授权
    Automatic brake booster 失效
    自动制动助力器

    公开(公告)号:US06332391B1

    公开(公告)日:2001-12-25

    申请号:US09350373

    申请日:1999-07-09

    IPC分类号: F15B1316

    摘要: In an automatic brake booster, a sleeve 18 constituting a valve mechanism 15 has a drive portion 50 disposed on the front side, a valve portion 51 forming a second valve seat 19, a mating portion 52 for mating with a valve seat portion when the drive portion is moved forward, and a conical spring 53 disposed between the drive portion and the valve seat portion and used for separating both members from each other. The conical spring is compressed during the normal braking operation so as to make the opening amount of the second valve seat greater than that during the automatic braking operation. Moreover, a plate plunger 40 for transmitting braking counterforce is relatively displaceably provided and a first member 71 and a second member 71 for mutually contacting a reaction disc 41 is also provided, so that the braking counterforce of the first member is transmitted to the sleeve during the automatic braking operation.

    摘要翻译: 在自动制动助力器中,构成阀机构15的套筒18具有设置在前侧的驱动部分50,形成第二阀座19的阀部分51,当驱动时与阀座部分配合的配合部分52 部分向前移动,以及设置在驱动部分和阀座部分之间并用于将两个部件彼此分离的锥形弹簧53。 锥形弹簧在正常制动操作期间被压缩,以使得第二阀座的打开量大于自动制动操作期间的开启量。 此外,用于传递制动力的板柱塞40相对可移动地设置,并且还设置用于相互接触反作用盘41的第一构件71和第二构件71,使得第一构件的制动反作用力在 自动制动操作。

    Semiconductive rubber roller
    83.
    发明授权
    Semiconductive rubber roller 有权
    半导电胶辊

    公开(公告)号:US06319181B1

    公开(公告)日:2001-11-20

    申请号:US09633100

    申请日:2000-08-04

    IPC分类号: B23P1500

    摘要: A semiconductive rubber roller used in a printer of a photocopying machine, which is an elongated integral body consisting of a shaft of a metal, a semiconductive foamed rubber layer on and around the shaft and a semiconductive solid, i.e. non-foamed, silicone rubber layer on and around the foamed rubber layer. Unexpected improvements can be obtained in the performance and durability of the roller when the silicone rubber forming the solid silicone rubber layer contains low molecular weight organopolysiloxane molecules having a degree of polymerization not exceeding 20 in an amount not exceeding 1.0% by weight and by providing the surface of the semiconductive solid silicone rubber layer with a covering layer which may be a coating layer of a resinous coating composition or a skin layer having a modified nature by a chemical or physical treatment such as ultraviolet irradiation.

    摘要翻译: 用于复印机的打印机中的半导体橡胶辊,其是由金属轴构成的细长整体,轴上和周围的半导体发泡橡胶层和半导体固体,即非发泡硅橡胶层 在发泡橡胶层上和周围。 当形成固体硅橡胶层的硅橡胶含有聚合度不超过20的低分子量有机聚硅氧烷分子,其量不超过1.0重量%时,可以在辊的性能和耐久性方面获得意想不到的改进,并且通过提供 具有覆盖层的半导体固体硅橡胶层的表面,其可以是树脂涂料组合物的涂层或通过化学或物理处理如紫外线照射具有改性的表皮层。

    Semiconductive silicone rubber roller thereof
    84.
    发明授权
    Semiconductive silicone rubber roller thereof 失效
    半导电硅胶辊

    公开(公告)号:US5827160A

    公开(公告)日:1998-10-27

    申请号:US818017

    申请日:1997-03-14

    摘要: Disclosed is an improvement in a rubber roller as a developing roller in a electrophotographic printer of which the silicone rubber forming the rubber layer on and around a metallic core mandrel is electrically semiconductive. The printing characteristics and abrasion resistance of the rubber roller to ensure good durability of the rubber roller in printing services can be greatly improved by the irradiation treatment of the rubber surface with ultraviolet light having principal wavelengths of 253.7 nm and 184.9 nm in an irradiation dose of 1.2 to 76 J/cm.sup.2, preferably, in an oxygen-containing atmosphere to form an ultraviolet-hardened surface layer of which the rubber surface has a specified surface rough-ness.

    摘要翻译: 公开了作为电子照相打印机中的显影辊的橡胶辊的改进,其中在金属芯心轴上和周围形成橡胶层的硅橡胶是半导电的。 通过以主要波长为253.7nm和184.9nm的紫外光照射处理橡胶表面,可以大大提高橡胶辊的印刷特性和耐磨性,以确保印刷服务中的橡胶辊的良好耐久性 1.2至76J / cm 2,优选在含氧气氛中形成紫外线硬化表面层,其中橡胶表面具有特定的表面粗糙度。

    Reaction mechanism for booster
    85.
    发明授权
    Reaction mechanism for booster 失效
    助推器的反应机理

    公开(公告)号:US5802952A

    公开(公告)日:1998-09-08

    申请号:US874373

    申请日:1997-06-19

    申请人: Masahiro Ikeda

    发明人: Masahiro Ikeda

    IPC分类号: B60T13/573 F15B9/10

    CPC分类号: B60T13/573

    摘要: According to the invention, the booster is not provided with a brake reaction transmission mechanism, and hence a reaction cannot be transmitted to a brake pedal. On the other hand, a pseudo-reaction imparting means is provided to impart a pseudo-reaction of suitable magnitude which depends on the degree of depression of the brake pedal. The pseudo-reaction imparting means is arranged so that when the brake pedal is depressed relatively rapidly, a relatively smaller braking reaction is imparted than during a usual depression. With this arrangement, the transmission of an abnormally high braking reaction to a driver which is experienced in a conventional booster during a quick braking operation due to an operational rag of the booster is avoided. The pseudo-reaction imparting means allows a reaction of a suitable magnitude which depends on the rate of depression of the brake pedal by a driver to be imparted, thus permitting a high output to be obtained with a reduced force of depression during a quick braking operation.

    摘要翻译: 根据本发明,增压器不设置制动反作用传动机构,因此反作用力不能传递到制动踏板。 另一方面,提供了伪反应赋予装置,以提供取决于制动踏板的压下程度的适当大小的伪反应。 假反应赋予装置被布置成使得当制动踏板相对较快地被压下时,施加比在通常的凹陷期间相对较小的制动反作用。 通过这种布置,避免了由于加速器的操作性破坏而在快速制动操作期间在常规助力器中经历的驾驶员异常高的制动反应的传递。 伪反应赋予装置允许通过驾驶员施加的取决于制动踏板的下压速率的适当大小的反应,从而允许在快速制动操作期间以减小的压力获得高输出 。

    Drop-out detecting circuit
    86.
    发明授权
    Drop-out detecting circuit 失效
    掉电检测电路

    公开(公告)号:US5418656A

    公开(公告)日:1995-05-23

    申请号:US972174

    申请日:1992-11-04

    IPC分类号: G11B20/18 H04N5/94

    CPC分类号: H04N5/94 G11B20/18

    摘要: To set the drop-out detection level constant in the drop-out detecting circuit used for a magnetic recording apparatus, without regulating the output level of a magnetic recording head and the gain of a preamplifier, the detecting circuit comprises an envelope detection section for detecting the envelope of a reproduced signal; a voltage division section for dividing the output signal voltage of the envelope detection section; and a comparator for comparing the output signal of the voltage division section with the reproduced signal to detect a drop-out of the reproduced signal. Therefore, it is possible to reduce the number of parts and the number of adjustment process to reduce the manufacturing cost thereof. Further, to detect the drop-out portion throughout as defective tape locations, irrespective of the length of the drop-out portion, the detecting circuit further comprises a drop-out start detection section, a drop-out end detection section, and an OR gate.

    摘要翻译: 为了在用于磁记录装置的脱出检测电路中设定脱出检测电平的常数,而不调节磁记录头的输出电平和前置放大器的增益,检测电路包括用于检测 再生信号的包络; 分压部,其对所述包络检测部的输出信号电压进行分压; 以及比较器,用于将分压部分的输出信号与再现信号进行比较,以检测再现信号的退出。 因此,可以减少部件的数量和调整过程的数量,以降低其制造成本。 此外,为了检测作为有缺陷的磁带位置的丢失部分,与检出电路的长度无关,检测电路还包括一个出口开始检测部分,一个退出结束检测部分和一个OR 门。

    Center bearing support
    87.
    发明授权
    Center bearing support 有权
    中心轴承支持

    公开(公告)号:US09328772B2

    公开(公告)日:2016-05-03

    申请号:US13613557

    申请日:2012-09-13

    申请人: Masahiro Ikeda

    发明人: Masahiro Ikeda

    IPC分类号: F16C35/04 F16C27/06 F16C33/80

    摘要: The invention provides a center bearing support which can effectively suppress an inflow of a muddy water or the like into a center bearing side even at a time when a rotating shaft stops, without using a contact type seal such as an oil seal or the like. In a center bearing support in which an inner ring retaining a center bearing is provided in an inner periphery of an outer ring fixed to a vehicle body side via an elastic body made of a rubber-like elastic material, a rib guiding a flow of a muddy water or the like in a circumferential direction is formed on a convex surface constructed by a bellow-like bent portion of the elastic body.

    摘要翻译: 本发明提供一种即使在旋转轴停止时也能够有效地抑制泥水等进入中心轴承侧的中心轴承座,而不使用诸如油封等的接触型密封。 在通过橡胶状弹性材料制成的弹性体将保持中心轴承的内圈设置在固定于车体侧的外圈的内周的中心轴承座中, 在由弹性体的波纹状弯曲部构成的凸面上形成有圆周方向的泥水等。

    Cooling device and construction machine or working machine equipped with the same
    88.
    发明授权
    Cooling device and construction machine or working machine equipped with the same 有权
    冷却装置和施工机械或工作机器配备相同

    公开(公告)号:US09228319B2

    公开(公告)日:2016-01-05

    申请号:US12675140

    申请日:2008-08-29

    摘要: A cooling device includes: a cooling fan; a shroud provided at an outer circumferential side of the cooling fan; an inner circumferential wall provided on the shroud and adjacent to the outer circumference of the cooling fan; and an outer circumferential wall provided to surround the inner circumferential wall. An air-flow-direction downstream side end of the outer circumferential wall is positioned at a further downstream position in an air flow direction than an air-flow-direction downstream side end of the inner circumferential wall. An air-flow-direction downstream side end of the cooling fan is positioned at a further downstream position than the air-flow-direction downstream side end of the inner circumferential wall. A ratio between a length of the outer circumferential wall and a length of the inner circumferential wall in the air flow direction is 1.07 or more and 1.81 or less, and a width between the outer circumferential wall and the inner circumferential wall is 15 mm or more and 55 mm or less.

    摘要翻译: 冷却装置包括:冷却风扇; 设置在所述冷却风扇的外周侧的护罩; 设置在所述护罩上且与所述冷却风扇的外周相邻的内周壁; 以及设置成围绕内周壁的外周壁。 外周壁的气流方向下游侧端部位于比内周壁的气流方向下游侧端部的空气流动方向更下游的位置。 冷却风扇的空气流动方向下游侧端部位于比内周壁的空气流动方向下游侧端部更靠下游的位置。 外周壁的长度与内周壁的空气流动方向的长度之比为1.07以上且1.81以下,外周壁与内周壁的宽度为15mm以上 和55mm以下。

    Particle beam therapy device and particle beam therapy device operation method
    90.
    发明授权
    Particle beam therapy device and particle beam therapy device operation method 有权
    粒子束治疗装置和粒子束治疗装置的操作方法

    公开(公告)号:US09067066B2

    公开(公告)日:2015-06-30

    申请号:US14356629

    申请日:2012-03-27

    IPC分类号: G21K5/04 A61N5/10

    摘要: A control unit is provided with, a retaining section that retains a plurality of operation patterns each being a pattern of operation to be periodically repeated by an accelerator, the operation patterns having respective operation conditions adjusted for different emission times of an particle beam, to cause a deflection electromagnet in the accelerator to have an intended magnetic field intensity even under a presence of a hysteresis; a reading section for a plurality of slices of an irradiation target in a depth direction, which reads an irradiation condition for each of the slices; a selection section that selects the operation pattern suitable for each of the slices, on the basis of the read irradiation condition; and a main control section that controls, for each of the slices, the accelerator on the basis of the selected operation pattern and an irradiation device on the basis of the irradiation condition.

    摘要翻译: 控制单元设置有保持部,其保持多个操作模式,每个操作模式是由加速器周期性重复的操作模式,所述操作模式具有针对粒子束的不同发射次数调整的各自的操作条件,以使得 加速器中的偏转电磁体即使在滞后的情况下也具有预期的磁场强度; 用于读取每个切片的照射条件的用于在深度方向上的照射目标的多个切片的读取部分; 选择部,其基于读取的照射条件选择适合于每个切片的操作模式; 以及主控制部,其基于所述照射条件,基于所选择的操作模式和照射装置对每个切片进行加速器的控制。