公开(公告)号：US5811439A

公开(公告)日：1998-09-22

申请号：US768937

申请日：1996-12-18

申请人： Masashi Ogawa ,  Tadashi Morita ,  Norihiro Iibuchi ,  Hideyuki Tsutsui

发明人： Masashi Ogawa ,  Tadashi Morita ,  Norihiro Iibuchi ,  Hideyuki Tsutsui

IPC分类号： A61K31/425 ,  A61K31/44 ,  A61K31/475 ,  A61P3/06 ,  A61P3/08 ,  A61P3/10 ,  C07D417/06 ,  C07D417/14

CPC分类号： C07D417/06 ,  C07D417/14

摘要： A thiazolidinedione derivative represented by the following general formula (I): ##STR1## �wherein the dotted line represents a single bond or a double bond, the thiazolidinedione ring residue is linked to either of 2-, 3-, 4-, 5- and 6-positions on the indole ring and R represents a group selected from the group consisting of hydrogen atom and alkyl, alkenyl, alkynyl, phenyl, aralkyl, heterocycloalkyl, arylsulfonyl and arylaminocarbonyl groups! or a pharmaceutically acceptable salt thereof exhibits excellent effects of reducing the blood sugar level and of reducing the lipid concentration in blood and is accordingly useful as a therapeutic agent for treating diabates mellitus. These derivatives and pharmaceutically acceptable salt thereof are almost free of any side effect.

摘要翻译： 由下列通式（I）表示的噻唑烷二酮衍生物：其中虚线代表单键或双键，噻唑烷二酮环残基与2-，3-，4- 在吲哚环上的5-和6-位，R表示选自氢原子和烷基，烯基，炔基，苯基，芳烷基，杂环烷基，芳基磺酰基和芳基氨基羰基的基团]或其药学上可接受的盐显示出优异的 降低血糖水平和降低血液中的脂质浓度的效果，因此可用作治疗二倍体的治疗剂。 这些衍生物及其药学上可接受的盐几乎没有副作用。

公开(公告)号：US5447846A

公开(公告)日：1995-09-05

申请号：US91661

申请日：1993-07-14

申请人： Hiroshi Shinoki ,  Masashi Ogawa

发明人： Hiroshi Shinoki ,  Masashi Ogawa

IPC分类号： G01N33/542 ,  G01N33/543 ,  G01N33/58 ,  G01N33/68 ,  G01N33/53

CPC分类号： G01N33/581 ,  G01N33/542 ,  G01N33/54386 ,  G01N33/6857 ,  Y10S435/964 ,  Y10S435/969 ,  Y10S435/97 ,  Y10S435/972 ,  Y10S530/866

摘要： An enzyme-labelled antibody adapted for use in a homogeneous immunoassay is provided. The enzyme-labelled antibody is a conjugate of an enzyme with two or more different monoclonal antibodies, each of the monoclonal antibodies being capable of specifically recognizing and binding to a different epitope of the same antigen. By using the enzyme-labelled antibody in the homogeneous enzyme immunoassay process, an analyte can be quantitatively analyzed at a higher sensitivity through a simple operation. Also provided is a dry immunoassay element comprising an immunological reaction layer containing the enzyme-labelled antibody. By the provision of such an immunoassay element, a further simplified quick analysis of an analyte is realized to give an accurate result.

摘要翻译： 提供适用于均相免疫测定法的酶标记抗体。 酶标记的抗体是酶与两种或更多种不同单克隆抗体的缀合物，每种单克隆抗体能够特异性识别并结合相同抗原的不同表位。 通过在均相酶免疫测定法中使用酶标记的抗体，可以通过简单的操作以更高的灵敏度对分析物进行定量分析。 还提供了包含含有酶标记抗体的免疫反应层的干免疫测定元件。 通过提供这样的免疫测定元件，实现了分析物的进一步简化的快速分析以给出准确的结果。

公开(公告)号：US4963243A

公开(公告)日：1990-10-16

申请号：US483317

申请日：1990-02-21

申请人： Masashi Ogawa ,  Hisashi Shiraishi ,  Teppei Ikeda

发明人： Masashi Ogawa ,  Hisashi Shiraishi ,  Teppei Ikeda

IPC分类号： G01N27/26 ,  G01N27/447

CPC分类号： G01N27/44747

摘要： In a medium for electrophoresis comprising a polyacrylamide gel formed by crosslinking polymerization of an acrylamide compound and a crosslinking agent in the presence of water, and a modifier, the improvement in which the medium contains a water-soluble polymer and agarose.

摘要翻译： 在包含通过丙烯酰胺化合物和交联剂在水存在下交联聚合形成的聚丙烯酰胺凝胶和改性剂的电泳介质中，介质含有水溶性聚合物和琼脂糖的改进。

公开(公告)号：US4844786A

公开(公告)日：1989-07-04

申请号：US160161

申请日：1988-02-25

申请人： Mitsuru Sugihara ,  Masashi Ogawa

发明人： Mitsuru Sugihara ,  Masashi Ogawa

IPC分类号： G01N27/447

CPC分类号： G01N27/44704 ,  G01N27/44747

摘要： A means for electrophoresis suitably employable for analysis of biopolymers such as proteins, as well as for determination of base sequence of DNA, RNA, their fragments, and their derivatives is disclosed. The means comprises a membrane of an aqueous polyacrylamide gel for electrophoresis which is sandwiched between a plane support and a plane covering sheet. The membrane has a thickness gradient in its electrophoresis direction.

公开(公告)号：US4722777A

公开(公告)日：1988-02-02

申请号：US903884

申请日：1986-09-03

申请人： Masashi Ogawa ,  Hideo Matsunaga ,  Yukio Shinagawa

发明人： Masashi Ogawa ,  Hideo Matsunaga ,  Yukio Shinagawa

IPC分类号： G01N27/447 ,  C25D13/02 ,  C25D13/08

CPC分类号： G01N27/44747

摘要： An element for electrophoresis suitably employable for analysis of biopolymers such as proteins, as well as for determination of base sequence of DNA, RNA, their fragments, and their derivatives, which comprises a plastic material support, an adhesive layer containing an inorganic oxide and a binder, a medium layer for electrophoresis comprising an aqueous polyacrylamide gel formed by crosslinking polymerization of an acrylamide compound and a crosslinking agent in the presence of water, and a plastic material covering film. The electrophoresis medium layer may contain a water-soluble polymer and agarose. The medium layer may contain a modifier such as an anionic surfactant, formamide or urea.

摘要翻译： 适用于分析生物聚合物如蛋白质的电泳元件，以及用于测定DNA，RNA，其片段及其衍生物的碱基序列，其包含塑料材料载体，含有无机氧化物的粘合剂层和 粘合剂，用于电泳的中间层，其包含通过在水存在下交联聚合丙烯酰胺化合物和交联剂而形成的聚丙烯酰胺凝胶水溶液和塑料材料覆盖膜。 电泳介质层可含有水溶性聚合物和琼脂糖。 中间层可以含有改性剂，例如阴离子表面活性剂，甲酰胺或脲。

公开(公告)号：US4650556A

公开(公告)日：1987-03-17

申请号：US710131

申请日：1985-03-11

申请人： Masakazu Hashiue ,  Masashi Ogawa ,  Daijiro Nishio

发明人： Masakazu Hashiue ,  Masashi Ogawa ,  Daijiro Nishio

IPC分类号： G01N27/447 ,  G01N27/26 ,  G01N27/28

CPC分类号： G01N27/44747

摘要： A medium for electrophoresis which is substantially free from smiling effect or is reduced in the smiling effect, in which both side portions along the direction of electrophoresis are made thicker than the center portion. A support preferably employed for the preparation of the medium is also disclosed.

摘要翻译： 基本上没有微笑效果的电泳介质或微笑效果的降低，其中沿着电泳方向的两侧部分比中心部分厚。 还公开了优选用于制备介质的载体。

公开(公告)号：US4640759A

公开(公告)日：1987-02-03

申请号：US710130

申请日：1985-03-11

申请人： Masakazu Hashiue ,  Masashi Ogawa

发明人： Masakazu Hashiue ,  Masashi Ogawa

IPC分类号： G01N27/447 ,  G01N27/28

CPC分类号： G01N27/44747

摘要： A process for electrophoresis employing a medium wherein the potential gradient along the direction of electrophoresis is made larger at both side portions of the medium than at the center portion thereof. A medium for employable for said process in that the length of the both side portions along the direction of electrophoresis is made shorter than that of the center portion is disclosed. Also disclosed is a support for the medium.

摘要翻译： 使用介质的电泳方法，其中沿着电泳方向的电位梯度在介质的两侧部比在其中心部分更大。 用于所述方法的介质是沿着电泳方向的两侧部分的长度比中心部分的长度被公开。 还公开了对该介质的支持。

公开(公告)号：US08935644B2

公开(公告)日：2015-01-13

申请号：US14234550

申请日：2012-07-27

申请人： Masashi Ogawa ,  Ken Morishita

发明人： Masashi Ogawa ,  Ken Morishita

IPC分类号： G06F9/455 ,  G06F17/50 ,  H05K3/00 ,  H05K1/02

CPC分类号： G06F17/5081 ,  G06F17/5036 ,  G06F17/5068 ,  G06F2217/82 ,  H05K1/023 ,  H05K1/0231 ,  H05K1/025 ,  H05K3/0005

摘要： A printed substrate design system includes: an EMI condition determination unit that compares an EMI characteristic derived by an EMI characteristic derivation unit with an EMI allowable condition, and determines whether the EMI characteristic of a printed substrate satisfies the EMI allowable condition; a substrate configuration change unit that changes an internal configuration of the printed substrate to obtain a changed configuration of the printed substrate in a case where the EMI condition determination unit has determined that the EMI allowable condition is not satisfied, and sets design information of the changed configuration of the printed substrate to design information for deriving the EMI characteristic in the EMI characteristic derivation unit; and an output unit that outputs a printed substrate configuration in a case where the EMI condition determination unit has determined the EMI allowable condition is satisfied.

摘要翻译： 印刷基板设计系统包括：EMI条件确定单元，其将由EMI特性导出单元导出的EMI特性与EMI可允许条件进行比较，并且确定印刷基板的EMI特性是否满足EMI允许条件; 基板配置改变单元，其在EMI条件确定单元已经确定不允许EMI可允许条件的情况下改变印刷基板的内部配置以获得印刷基板的改变的配置，并且设置改变的设计信息 印刷基板的结构，以设计用于导出EMI特性导出单元中的EMI特性的信息; 以及输出单元，其在EMI条件确定单元已经确定了EMI允许条件的情况下输出打印的基板结构。

公开(公告)号：US08847211B2

公开(公告)日：2014-09-30

申请号：US13510178

申请日：2010-11-18

申请人： Seiji Shinkai ,  Shuichi Haraguchi ,  Tomohiro Shiraki ,  Masashi Ogawa ,  Shuhei Nakatani ,  Kei Sakanoue ,  Osamu Goto ,  Hidenobu Kakimoto

发明人： Seiji Shinkai ,  Shuichi Haraguchi ,  Tomohiro Shiraki ,  Masashi Ogawa ,  Shuhei Nakatani ,  Kei Sakanoue ,  Osamu Goto ,  Hidenobu Kakimoto

IPC分类号： H01L35/24

CPC分类号： H01L51/0512 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1011 ,  C09K2211/1029 ,  G03F7/0046 ,  H01L27/3246 ,  H01L51/0558 ,  H01L51/56 ,  H01L2227/323 ,  H05B33/10

摘要： A problem of the present invention is to provide a device having good characteristics and long life, wherein a functional thin film is formed in a desired region by a coating method; a thin film transistor; a method for producing the device; and a method for producing the thin film transistor. This problem can be solved by a device comprising: a substrate, a first electrode formed on the substrate, a functional thin film formed above the first electrode, and a second electrode disposed above the functional thin film, characterized by further comprising, in a region surrounding the region where the functional thin film is formed, a film containing a compound in which a group containing fluorine and a π-conjugated system are bound together by a cycloalkene structure or a cycloalkane structure.

摘要翻译： 本发明的一个问题是提供一种具有良好特性和长寿命的器件，其中通过涂覆方法在所需区域中形成功能性薄膜; 薄膜晶体管; 一种制造该装置的方法; 以及薄膜晶体管的制造方法。 这个问题可以通过一种器件来解决，该器件包括：衬底，形成在衬底上的第一电极，形成在第一电极上的功能性薄膜，以及设置在功能性薄膜上方的第二电极，其特征在于， 围绕形成功能性薄膜的区域，含有其中含氟基团和共轭体系的基团通过环烯烃结构或环烷烃结构结合在一起的化合物的膜。

公开(公告)号：US08721933B2

公开(公告)日：2014-05-13

申请号：US12047233

申请日：2008-03-12

申请人： Hiroshi Mizuno ,  Akihiro Horii ,  Noriyuki Hirai ,  Masashi Ogawa ,  Yuu Miura ,  Kei Obata ,  Makoto Aoki

发明人： Hiroshi Mizuno ,  Akihiro Horii ,  Noriyuki Hirai ,  Masashi Ogawa ,  Yuu Miura ,  Kei Obata ,  Makoto Aoki

IPC分类号： B29D11/00

CPC分类号： B29C59/04 ,  B29D11/00663 ,  B32B37/1027 ,  B32B38/06 ,  B32B2307/40

摘要： A manufacture method of an optical sheet made of a transparent thermoplastic resin sheet on whose surface a regular geometric design working is performed, the optical sheet manufacture method comprising steps of performing a geometric design working on the resin sheet at a temperature not lower than a glass transition temperature of the resin sheet, by using a metal endless working belt formed with a geometric design on a surface thereof, rapidly cooling the resin sheet on which the geometric design working is performed to a temperature lower than the glass transition temperature, and detaching the rapidly cooled resin sheet from the metal endless working belt.

摘要翻译： 一种由透明热塑性树脂片制成的光学片的制造方法，其表面进行规则的几何设计，光学片制造方法包括以下步骤：在不低于玻璃的温度下对树脂片进行几何设计 通过使用在其表面上形成有几何设计的金属环形工作带，将其上进行几何设计的树脂板快速冷却至低于玻璃化转变温度的温度，并且分离所述树脂片的转变温度 从金属环形工作带快速冷却树脂板。