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    Virus separation
    82.
    发明授权
    Virus separation 失效
    病毒分离

    公开(公告)号：US3925152A

    公开(公告)日：1975-12-09

    申请号：US42373073

    申请日：1973-12-11

    Applicant: EXPLOATERINGS AB TBF

    Inventor： PORATH JERKER OLOF ,  JANSON JAN-CHRISTER

    IPC: B01J20/22 ,  B01J43/00 ,  B01J47/00 ,  C12N7/02 ,  C12K7/00

    CPC classification number: C12N7/00 ,  B01J20/22 ,  B01J43/00 ,  B01J47/014 ,  C12N2770/18051

    Abstract: The present invention relates to a method of separating a mixture of charged colloidal particles, e.g. virus variants by bringing the mixture to pass a bed of an adsorbent. The invention is mainly characterized in that the adsorbent is constituted of an insoluble, organic polymer containing amphoteric substituents composed of both basic nitrogen-containing groups and carboxylate or sulphonate groups. The proportion between the basic and the acid groups is simple and stoichiometric, whereby said charged particles are allowed to migrate at different speeds depending on the strength of the reciprocal interaction between the charged particles and the substituents in said adsorbent and are selectively adsorbed by said adsorbent.

    Waste treatment
    83.
    发明授权
    Waste treatment 失效
    废物处理

    公开(公告)号：US3803030A

    公开(公告)日：1974-04-09

    申请号：US27933972

    申请日：1972-08-10

    Applicant: FRAM CORP

    Inventor： MONTANARO R ,  MOREAU H

    IPC: B01D15/00 ,  B01J47/00 ,  C02F1/28 ,  B01D15/06

    CPC classification number: C02F1/285 ,  B01D15/00 ,  B01J47/014 ,  Y10S203/17

    Abstract: The process of removing contaminants from a liquid medium, comprising the steps of A. CONTACTING A QUANTITY OF THE CONTAMINATED LIQUID MEDIUM WITH A SOLVENT REGENERABLE FIRST ADSORBENT DURING A FIRST PHASE, THAT ADSORBENT HAVING AN AFFINITY FOR THE CONTAMINANTS AND A VOLUME WHICH ARE INSUFFICIENTLY HIGH TO PRODUCE A DESIRED DEGREE OF PURIFICATION DURING THE FIRST PHASE, WHEREBY A FRACTION OF THE CONTAMINANTS IS ADSORBED BY THE FIRST ADSORBENT AND A PARTIALLY PURIFIED EFFLUENT OF THE MEDIUM IS PRODUCED, B. CONTACTING THE PARTIALLY PURIFIED EFFLUENT FROM SAID FIRST PHASE WITH AN IONIC SOLUTION REGENERABLE SECOND ADSORBENT HAVING AN AFFINITY FOR THE CONTAMINANTS AND A VOLUME WHICH ARE SUFFICIENTLY HIGH TO PRODUCE THE DESIRED DEGREE OF PURIFICATION, C. REGENERATING THE FIRST ADSORBENT WITH A SOLVENT, D. CONTACTING A REGENERANT WITH THE SECOND ADSORBENT TO REMOVE THE CONTAMINANTS ADSORBED THEREON, AND E. CONTACTING THE EFFLUENT FROM STEP (D), COMPRISING THE REGENERANT AND THE CONTAMINANTS REMOVED THEREBY, WITH THE FIRST ADSORBENT, WHEREBY AN ADDITIONAL FRACTION OF THE CONTAMINANTS IS ADSORBED BY THE FIRST ADSORBENT.

    Method for recharging an ion exchange resin
    84.
    发明授权
    Method for recharging an ion exchange resin 失效
    补充离子交换树脂的方法

    公开(公告)号：US3658698A

    公开(公告)日：1972-04-25

    申请号：US3658698D

    申请日：1970-03-16

    Applicant: TECHNICRAFT INTERNATIONAL INC

    Inventor： YOUNG DAVID P

    IPC: B01J47/00 ,  G01N33/78 ,  B01D15/06

    CPC classification number: G01N33/78 ,  B01J47/014

    Abstract: A method for recharging and purifying an acetate group ion exchange resin which has been used to isolate thyroxine from blood serum. The method includes treatment with an aqueous concentrated acetic acid solution optionally followed by treatment with an aqueous metallic acetate solution.

    Abstract translation: 一种用于从血清中分离甲状腺素的乙酸酯基离子交换树脂的再充电和纯化方法。 该方法包括用浓缩的乙酸水溶液处理，随后用金属乙酸盐水溶液处理。

    Antibiotic purification process
    85.
    发明授权
    Antibiotic purification process 失效
    抗生素净化工艺

    公开(公告)号：US3641063A

    公开(公告)日：1972-02-08

    申请号：US3641063D

    申请日：1968-01-22

    Applicant: MERCK & CO INC

    Inventor： MILLER THOMAS W

    IPC: B01J47/00 ,  C07F9/38 ,  C07F9/40

    CPC classification number: B01J47/014 ,  Y10S435/803 ,  Y10S435/896

    Abstract: METHOD FOR RECOVERING ANTIBIOTIC 833A, CHEMICALLY KNOWN AS (-)(CIS-1,2-EPOXYPROPYL)PHOSPHONIC ACID, FROM IMPURE AQUEOUS SOLUTIONS CONTAINING SAID ANTIBIOTIC, VIA ADSORPTION ON ION EXCHANGE RESINS WITH SUBSEQUENT ELUTION WITH WATER, AQEOUS SALT SOLUTIONS OR AQUEOUS ALCOHOLIC SALT SOLUTIONS. ANTIBIOTIC 833A IS ACTIVE AGAINST BOTH GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA.

    Abstract translation: 1,224,768。 纯化抗生素833A。 MERCK＆CO。Inc. 1968年9月12日[1968年1月22日]，第43437/68号。 标题C2A。 通过使发酵液或含有所述抗生素的溶液通过阴离子交换树脂或阳离子交换树脂的柱来纯化抗生素833A，即（ - ）（顺式-1,2-环氧丙基）膦酸， 用洗脱溶剂洗脱树脂吸收物质，收集洗脱液，并结合活性级分。 阴离子交换树脂可以由连接到苯乙烯二乙烯基苯聚合物晶格的季铵交换基团组成。 阳离子交换树脂可以由连接到苯乙烯二乙烯基苯聚合物晶格的核磺酸交换基团组成。 洗脱溶剂可以是水溶性碱金属NH 4或三（羟甲基）氨基甲烷盐的水溶液。 通过浓缩合并的活性级分，将残余物溶解在水中，将得到的水溶液色谱分析为能够在分子量为200-2000的物质上操作的50至200目的聚丙烯酰胺凝胶上，从而获得进一步的纯化。

    Orgotein purification process by heating above 65{20 {0 c.
    86.
    发明授权
    Orgotein purification process by heating above 65{20 {0 c. 失效
    ORGOTEIN净化工艺通过加热65 {20 {0 C.

    公开(公告)号：US3624251A

    公开(公告)日：1971-11-30

    申请号：US3624251D

    申请日：1970-01-16

    Applicant: DIAGNOSTIC DATA INC

    Inventor： HUBER WOLFGANG

    IPC: B01J47/00 ,  C12N9/02 ,  A61K17/00 ,  C07G7/04

    CPC classification number: C12N9/0089 ,  B01J47/014 ,  C12Y115/01001 ,  Y10S530/846

    Abstract: Heat labile tenacious proteins present in samples of substantially pure orgotein produced by a process which comprises a heating step in which a mixture of proteins comprising the orgotein protein and substantial amounts of other proteins are heated under conditions which do not affect the orgotein, are eliminated therefrom by a second heating step of a solution of the substantially pure orgotein in a buffer containing divalent metal ions at a temperature higher than employed in the prior heating step.

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