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    Nontoxic compounds for use as taggants in nutritional and pharmaceutical products
    81.
    发明授权
    Nontoxic compounds for use as taggants in nutritional and pharmaceutical products 有权

    公开(公告)号：US11353469B2

    公开(公告)日：2022-06-07

    申请号：US16432898

    申请日：2019-06-05

    Applicant: Hall Labs, LLC

    Inventor： David R Hall ,  Steven J. M. Butala

    IPC: G01N33/94 ,  G01N33/493 ,  G01N33/52 ,  G01N33/58 ,  G01N33/497 ,  G01N33/15

    Abstract: The method of confirming consumption of a tagged pharmaceutical or nutritional product includes the step of providing a subject with a pharmaceutical or nutritional product which has been tagged with a safe, for example, a plant-based, compound. These compounds may include asparagusic acid or a derivative thereof which is found in asparagus, garlic or an extract of garlic, or 1,8-cineole. Alternatively, the taggant may be dimethylsulfoxide. A subject may be provided with and instructed to consume the tagged product according to a defined protocol. A sample of bodily waste or other biological sample may be collected from the subject and analyzed for the presence of the tag or a metabolite thereof. This method may be used to confirm compliance with the protocol in clinical drug trials or nutritional studies.

    Individualized care management system based on digestive activity
    84.
    发明授权
    Individualized care management system based on digestive activity 有权

    公开(公告)号：US11315686B2

    公开(公告)日：2022-04-26

    申请号：US16145593

    申请日：2018-09-28

    Applicant: Vivante Health, Inc.

    Inventor： Kimon Angelides

    IPC: G16H50/00 ,  G16H50/20 ,  G16H40/63 ,  G16H10/40 ,  G01N33/483 ,  G01N33/497 ,  C12Q1/04

    Abstract: Embodiments of this invention include systems and methods for developing individualized dietary and health improvement plans based on an individual's intestinal microbiome and digestive activity. More particularly, the invention is related to a system providing a hydrogen and/or methane sensor device and a wireless platform in communication with the sensor device to periodically analyze the individual's metabolic activity in correlation with their gut microbiome and a personal database to provide personalized feedback to the individual of treatment plans and general techniques that can be used to improve the individual's general health and well being. The systems and methods further include a system for analyzing the hydrogen and/or methane levels in the individual's exhalations or flatulence in light of the individual's intestinal microbiome. This analysis uses bioinformatics to relate alterations in hydrogen and/or methane levels to the individual's intestinal microbiome and personal diet and tolerances/intolerances to identify and communicate real time dietary suggestions and general dietary and health treatment plans. The relationship of the bioinformatics and alterations in hydrogen and/or methane levels is also used to infer drug effectiveness. Such general dietary guidance, health treatment plans, and drug effectiveness contribute to an overall improvement in a person's general health and well being.

    Pathogen Detection Apparatus and Method
    85.
    发明申请
    Pathogen Detection Apparatus and Method 有权

    公开(公告)号：US20220113294A1

    公开(公告)日：2022-04-14

    申请号：US17498441

    申请日：2021-10-11

    Applicant: Yonatan Gerlitz

    Inventor： Yonatan Gerlitz

    IPC: G01N33/497 ,  G01N27/49

    Abstract: Pathogen detection includes providing a sensor having first conductive lines alternated with second conductive lines, the first and second lines being formed over a substrate providing electrical isolation between the first and second lines and being at least partially exposed. Via voltage circuitry, a voltage difference is applied between the first and second lines. A user's breath is applied to the sensor and contacts exposed parts of the first lines simultaneous to exposed parts of the second lines. Pathogens from the user's breath bridge the electrical isolation between an individual first line and an opposing, individual second line and cause a short circuit. Via a comparator or controller, a current is detected flowing in the first and second lines due to the short circuit through the pathogens. A warning module indicates that the comparator or controller detected that the current is above a warning threshold.

    Chemically sensitive field effect transistors and uses thereof in electronic nose devices
    88.
    发明授权
    Chemically sensitive field effect transistors and uses thereof in electronic nose devices 有权

    公开(公告)号：US11243186B2

    公开(公告)日：2022-02-08

    申请号：US16000121

    申请日：2018-06-05

    Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.

    Inventor： Hossam Haick

    IPC: G01N27/414 ,  H01L29/772 ,  B82Y15/00 ,  B82Y30/00 ,  G01N33/543 ,  H01L29/08 ,  G01N33/00 ,  G01N33/497

    Abstract: A system having an electronic device. The electronic device has an array of chemically sensitive sensors. The sensors detect volatile organic compounds and have field effect transistors. The transistors have non-oxidized, functionalized silicon nanowires. The nanowires have surface Si atoms. The device has a plurality of functional groups that form a direct Si—C bond with the silicon nanowires, wherein Si is a surface Si atom and C is a carbon atom of the functional group. The functional groups are selected from the group consisting of: alkyl, cycloalkyl, alkenyl, alkynyl, aryl, heterocyclyl, heteroaryl, alkylaryl, alkylalkenyl, alkylalkynyl, alkylcycloalkyl, alkylheterocyclyl and alkylheteroaryl groups, and derivatives thereof, wherein said functional groups are other than methyl and 1-butyl. The plurality of functional groups are attached to 50-100% of the surface Si atoms.

    Exhaled gas detector and exhaled gas detection method
    90.
    发明授权
    Exhaled gas detector and exhaled gas detection method 有权

    公开(公告)号：US11226329B2

    公开(公告)日：2022-01-18

    申请号：US16535173

    申请日：2019-08-08

    Applicant: HITACHI, LTD.

    Inventor： Masuyoshi Yamada ,  Hironori Wakana

    IPC: G01N33/497

    Abstract: An exhaled gas detector includes: a gas detection element configured to measure a specific gas; and an analysis unit configured to analyze a signal output from the gas detection element. The gas detection element measures the specific gas in an exhalation of non-drinking time and generates a first reference signal value. The analysis unit calculates a first threshold value on the basis of the first reference signal value. The gas detection element measures the specific gas in an inspection gas and generates a first measurement signal value. The analysis unit determines that the inspection gas is identified with an exhalation of a person by determining that the first measurement signal value has exceeded the first threshold value.

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