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公开(公告)号：US20130149706A1
公开(公告)日：2013-06-13
申请号：US13761447
申请日：2013-02-07
申请人： APDN (B.V.I.) INC.
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6876 , B82Y15/00 , C08K5/09 , C09D7/63 , C09D11/03 , C12Q1/6816 , Y10S977/774 , Y10S977/92 , Y10T436/14 , Y10T436/143333 , C12Q2563/185
摘要： This invention provides compositions that have a light emitting reporter linked to biomolecules, preferably, nucleotide oligomers. The light reporter particles are silylated and functionalized to produce a coated light reporter particle, prior to covalently linking the biomolecules to the light reporter particle. The light reporter particles of the invention can be excited by a light excitation source such as UV or IR light, and when the biomolecule is DNA, the attached DNA molecule(s) are detectable by amplification techniques such as PCR.
摘要翻译： 本发明提供具有与生物分子连接的发光报道基团的组合物，优选核苷酸寡聚体。 在将生物分子共价连接到光报告颗粒之前，光报告颗粒被甲硅烷基化和官能化以产生包被的光报告颗粒。 本发明的光报告颗粒可以通过诸如UV或IR光的光激发源激发，并且当生物分子是DNA时，通过诸如PCR的扩增技术检测所连接的DNA分子。
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公开(公告)号：US10745825B2
公开(公告)日：2020-08-18
申请号：US16028176
申请日：2018-07-05
申请人： APDN (B.V.I.) INC.
IPC分类号： B29C65/00 , B29C65/48 , B29C71/00 , B32B37/00 , B41M3/14 , G07D7/14 , C40B20/04 , G07D7/1205 , B42D25/00 , C09B11/22 , C09B11/24 , C09B69/10 , C09B11/08 , C12Q1/68 , C09B23/16 , C09B57/10 , G07D7/202 , C12Q1/6876
摘要： Encrypted markers that are not readily detectable can be revealed by treatment with a specific reagent used as a developer to reveal a readily detectable physical property of the marker, such as a characteristic fluorescence emission after excitation with a particular excitation wavelength, or to reveal a visible color. The encrypted marker can be developed in situ, or a sample can be removed by brushing, scraping, swabbing or scratching the marked object or item and developing the encrypted marker or a sample thereof with the appropriate developer to reveal an overt marker or optical signal. The encrypted marker may include a DNA taggant.
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公开(公告)号：US09904734B2
公开(公告)日：2018-02-27
申请号：US15027454
申请日：2014-10-07
申请人： APDN (B.V.I.) INC.
发明人： Judith Murrah , Phidung H. Tran , Maciej B. Szczepanik , MingHwa Benjamin Liang , James A. Hayward
CPC分类号： G06F17/30876 , G06K7/0004 , G06K19/06037 , G06K19/0723
摘要： A multi-mode reader instrument capable of detecting and determining digital data from a signal from one or more markers, indicia or taggants on an object, the markers, indicia or taggants such as a bar code, a QR code, an RFID, an optical compound, a fluorescent compound, a phosphorescent compound, a DNA taggant, an upconverting phosphor (UCP), a chemical dye, a digitized image, a radioactive compound, an olfactory compound or a thermal attribute of the object is provided. Also, provided is a method and a system for identifying an object, the system includes: a multi-mode reader instrument for detecting data from a signal from one or more markers, indicia or taggants on an object and assignment of digital code for the marker and a database for securing and retrieving information relevant to the item.
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公开(公告)号：US20150266332A1
公开(公告)日：2015-09-24
申请号：US14661489
申请日：2015-03-18
申请人： APDN (B.V.I.) INC.
IPC分类号： B42D25/415 , B42D25/36
CPC分类号： C09K11/06 , B29C65/4825 , B29C66/733 , B41M3/142 , B41M3/144 , B42D2035/34 , G07D7/14
摘要： Encrypted markers that are not readily detectable can be revealed by treatment with a specific reagent used as a developer to reveal a readily detectable physical property of the marker, such as a characteristic fluorescence emission after excitation with a particular excitation wavelength, or to reveal a visible color. The encrypted marker can be developed in situ, or a sample can be removed by brushing, scraping, swabbing or scratching the marked object or item and developing the encrypted marker or a sample thereof with the appropriate developer to reveal an overt marker or optical signal. The marker can be revealed by exposure of the encrypted marker or a sample thereof to the developer in any suitable form, such as a solution, a slurry, a swab, a solid (such as in granular form), or a gas or a vapor that includes a developer.
摘要翻译： 通过用用作显色剂的特定试剂进行处理，可以显示不容易检测到的加密标记物，以显示标记的易于检测的物理性质，例如用特定激发波长激发后的特征性荧光发射，或显示可见光 颜色。 可以原位开发加密的标记，或者可以通过刷涂，刮擦，擦拭或刮擦标记的物体或物品并用合适的显影剂开发加密标记或样品，以揭示公开标记或光信号来移除样品。 可以通过将加密的标记物或其样品以任何合适的形式（例如溶液，浆液，拭子，固体（例如颗粒形式））或气体或蒸汽暴露于显影剂来显示标记 包括开发人员。
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公开(公告)号：US09005985B2
公开(公告)日：2015-04-14
申请号：US13761447
申请日：2013-02-07
申请人： APDN (B.V.I.) Inc.
CPC分类号： C12Q1/6876 , B82Y15/00 , C08K5/09 , C09D7/63 , C09D11/03 , C12Q1/6816 , Y10S977/774 , Y10S977/92 , Y10T436/14 , Y10T436/143333 , C12Q2563/185
摘要： This invention provides compositions that have a light emitting reporter linked to biomolecules, preferably, nucleotide oligomers. The light reporter particles are silylated and functionalized to produce a coated light reporter particle, prior to covalently linking the biomolecules to the light reporter particle. The light reporter particles of the invention can be excited by a light excitation source such as UV or IR light, and when the biomolecule is DNA, the attached DNA molecule(s) are detectable by amplification techniques such as PCR.
摘要翻译： 本发明提供具有与生物分子连接的发光报道基团的组合物，优选核苷酸寡聚体。 在将生物分子共价连接到光报告颗粒之前，光报告颗粒被甲硅烷基化和官能化以产生包被的光报告颗粒。 本发明的光报告颗粒可以通过诸如UV或IR光的光激发源激发，并且当生物分子是DNA时，通过诸如PCR的扩增技术检测所连接的DNA分子。
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公开(公告)号：US08372648B2
公开(公告)日：2013-02-12
申请号：US11954030
申请日：2007-12-11
申请人： Thomas Kwok , Ming-Hwa Liang , Stephane Shu Kin So
发明人： Thomas Kwok , Ming-Hwa Liang , Stephane Shu Kin So
CPC分类号： C12Q1/6876 , B82Y15/00 , C08K5/09 , C09D7/63 , C09D11/03 , C12Q1/6816 , Y10S977/774 , Y10S977/92 , Y10T436/14 , Y10T436/143333 , C12Q2563/185
摘要： This invention provides compositions that have a light emitting reporter linked to biomolecules, preferably, nucleotide oligomers. The light reporter particles are silylated and functionalized to produce a coated light reporter particle, prior to covalently linking the biomolecules to the light reporter particle. The light reporter particles of the invention can be excited by a light excitation source such as UV or IR light, and when the biomolecule is DNA, the attached DNA molecule(s) are detectable by amplification techniques such as PCR.
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公开(公告)号：US10760182B2
公开(公告)日：2020-09-01
申请号：US14572552
申请日：2014-12-16
申请人： APDN (B.V.I.) Inc.
IPC分类号： C12Q1/68 , D01B1/04 , D06M15/01 , D06M16/00 , D01G99/00 , D01B9/00 , D06H1/00 , D06M101/12 , D06M101/06
摘要： A method of marking fibers, wherein the method includes providing a plurality of fibers; depositing a marker onto at least a portion of the fibers, the depositing being performed with a delivery mechanism comprising one or more outlets; and thereby marking the fibers. Also provided is a device for marking fibers, including a transport system adapted to transport fibers in a direction of a marker delivery apparatus positioned along the transport system; the delivery apparatus includes one or more outlets, adapted to deposit a solution of the marker through the outlets onto at least a portion of the fibers; and thereby marking the fibers. Authentication of a fibrous material using the marking method of the invention followed obtaining a sample of the marked fibers and assaying the sample for the presence of the nucleic acid marker; and thereby determining whether the fibrous material is authentic or counterfeit.
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8.发明申请公开(公告)号：US20190241982A1
公开(公告)日：2019-08-08
申请号：US16265631
申请日：2019-02-01
申请人： APDN (B.V.I.) Inc.
发明人： Michael E. HOGAN , Gordon HOPE , James A. HAYWARD , John SHERMAN , Thomas ACKERMAN , Brian VISCOUNT
IPC分类号： C12Q1/6895
CPC分类号： C12Q1/6895
摘要： The invention provides for a system to track the origin of cannabis products and cannabis derivative products without the need for packaging or labeling through the use of nucleic acid tags. The invention further provides for a method of tracking the origin of cannabis products and cannabis derivative products via the application of nucleic acid tags to cannabis plants.
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公开(公告)号：US09963740B2
公开(公告)日：2018-05-08
申请号：US14497614
申请日：2014-09-26
申请人： APDN (B.V.I.) Inc.
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6876 , C12Q1/6816 , C12Q2563/185
摘要： Provided are a method and device for marking an article for security, tracking or authentication. The method includes depositing a solution comprising a nucleic acid marker onto at least a portion of the article. The nucleic acid marker may be activated, for example, by adding a functional group to the nucleic acid marker. The activation of the nucleic acid marker may be performed by exposure to alkaline conditions. The method is well suited for marking fibers and textiles, as well as many other items.
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公开(公告)号：US09790538B2
公开(公告)日：2017-10-17
申请号：US13789093
申请日：2013-03-07
申请人： APDN (B.V.I) INC.
IPC分类号： C12Q1/68
CPC分类号： C12Q1/68 , C12Q1/6802 , C12Q2563/185
摘要： The invention provides methods for stably binding and immobilizing deoxyribonucleic acid onto objects and substrates. The method includes exposing the deoxyribonucleic acid to alkaline conditions, and contacting the deoxyribonucleic acid to the object or substrate. The alkaline conditions are produced by mixing the deoxyribonucleic acid with an alkaline solution having a pH of about 9.0 or higher, and contacting the deoxyribonucleic acid to the substrate. The immobilized DNA can be used as a taggant and can be used in combination with other detectable taggants, such as optical reporters. Methods for authentication of a DNA marked object are also provided.
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