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公开(公告)号：US08855903B2
公开(公告)日：2014-10-07
申请号：US14256756
申请日：2014-04-18
发明人： Yi-Chang Chiu
CPC分类号： G08G1/09 , G01C21/3492 , G06Q10/047 , G06Q30/02 , G06Q30/0207 , G08G1/0112 , G08G1/0129 , G08G1/0141 , G08G1/096811 , G08G1/096838 , Y10S430/137
摘要： Systems and methods for providing incentives for the public to travel during time windows and routes that help alleviate traffic congestion. The systems described herein include at least two components: a computer server software system that includes various algorithms and database sub-systems; and a mobile device application. Generally, a user may enter an origin, destination, and preferred time of travel for an intended trip into the mobile device application, which transmits the information to a remote server. The server computes a route for the trip and provides the user with available incentives for traveling the route at one or more departure time windows. The user's mobile device transmits GPS data to the server, which allows the server to verify whether the user has traveled the route during the specified time window. If so, the server then provides the incentive to the user via the user's mobile device or through email.
摘要翻译： 提供激励措施的制度和方法，使公众在时间窗口和路线上旅行，有助于减轻交通拥堵。 本文描述的系统包括至少两个组件：包括各种算法和数据库子系统的计算机服务器软件系统; 和移动设备应用程序。 通常，用户可以输入到移动设备应用程序的预期行程的起始，目的地和优选时间，其将信息发送到远程服务器。 服务器计算旅程的路线，并为用户提供在一个或多个出发时间窗口上行驶路线的可用激励。 用户的移动设备向服务器发送GPS数据，这允许服务器在指定的时间窗口期间验证用户是否已经行进路线。 如果是这样，服务器然后通过用户的移动设备或通过电子邮件向用户提供激励。
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2.发明公开公开(公告)号：US20240361752A1
公开(公告)日：2024-10-31
申请号：US18649576
申请日：2024-04-29
发明人： Winslow Burleson , Michael Lombardi
IPC分类号： G05B19/4155
CPC分类号： G05B19/4155 , G05B2219/40271
摘要： A networked system architecture including hardware and software elements permits data transmission between underwater systems. The network architecture includes data transmission between underwater computers, instruments, robotic vehicles, human-occupied underwater habitats, and/or worn sensor devices. Data is transmitted over wired communication channels, wireless communication channels, or a combination thereof. The network is established independent of surface connectivity (e.g., a topside connection) and creates a Local Area Network (LAN) or Wide Area Network (WAN) specific to an underwater environment. A system administrator, such as a diver, operates an underwater and waterproof computer to control and operate an underwater and waterproof device (e.g., a robotic vehicle) over the LAN/WAN. The underwater device may be a remotely operated vehicle (ROV), an autonomous underwater vehicle (AUV), a drifting sensor, a moored sensor, or the like.
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公开(公告)号：US20240360107A1
公开(公告)日：2024-10-31
申请号：US18687664
申请日：2022-08-30
发明人： Eli Chapman , Christopher Zerio
IPC分类号： C07D405/04 , A61K31/4709
CPC分类号： C07D405/04 , A61K31/4709
摘要： The present invention features inhibitors of the eIF4A enzyme. These inhibitors have a novel mechanism for inhibiting the eIF4A enzyme by occupying a binding pocket within the eIF4A RNA-binding groove, thereby perturbing RNA binding, blocking ATP hydrolysis, and, consequently, inhibiting RNA helicase activity. Thus, the compounds of the present invention are RNA-competitive, ATP-uncompetitive elF4A inhibitors that directly bind elF4A and inhibit the protein.
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公开(公告)号：US12118895B2
公开(公告)日：2024-10-15
申请号：US17048991
申请日：2019-04-18
发明人： Samuel Barber , Saurabh Jain , Young-Jun Son , Eugene Chang
IPC分类号： G09B23/28 , A61B17/24 , A61B34/10 , A61B34/20 , A61B90/00 , B33Y80/00 , G06F3/01 , G06F3/0346 , G06T7/11 , G09B23/30 , G16H20/40 , G16H40/63 , G16H50/50 , A61B17/00 , A61B17/29 , A61B17/32 , A61B17/3201 , A61B18/00 , A61B18/14 , A61B90/50
CPC分类号： G09B23/285 , A61B17/24 , A61B34/10 , A61B34/20 , A61B90/36 , B33Y80/00 , G06F3/011 , G06F3/012 , G06F3/016 , G06F3/0346 , G06T7/11 , G09B23/30 , G16H20/40 , G16H40/63 , G16H50/50 , A61B2017/00119 , A61B2017/00216 , A61B2017/00707 , A61B2017/00716 , A61B17/29 , A61B17/320016 , A61B17/3201 , A61B2018/00297 , A61B18/14 , A61B2034/101 , A61B2034/105 , A61B2034/107 , A61B2090/365 , A61B2090/372 , A61B2090/502 , G06T2207/10068 , G06T2207/10072 , G06T2207/30004
摘要： An apparatus has a device representing an endoscope, the device being either an endoscope or a dummy endoscope having shape and feel resembling an endoscope, and includes a tracker adapted to operate with a three-dimensional tracking system to track location and orientation of the device in three dimensions in a simulated operating-room environment. The apparatus also has a physical head model comprising hard and soft components, the device representing an endoscope configured to be inserted into the physical head model to provide a haptic feedback of endoscopic surgery.
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公开(公告)号：US12102997B2
公开(公告)日：2024-10-01
申请号：US18007456
申请日：2021-07-30
IPC分类号： B01L3/00 , A01N1/02 , A01N59/04 , A01P1/00 , A61B5/097 , A61B10/00 , A61L2/00 , A61L2/24 , A61L101/02
CPC分类号： B01L3/502 , A01N59/04 , A01P1/00 , A61B5/097 , A61B10/0051 , A61B10/0096 , A61L2/0023 , A61L2/24 , A61L2101/02 , A61L2202/14 , A61L2202/18 , B01L2200/0678 , B01L2200/185 , B01L2300/042 , B01L2300/0681 , B01L2300/069 , B01L2300/14 , B01L2300/1894
摘要： Provided herein are portable biocontainment devices for safe and reliable collection of biological samples, including liquid and gas samples. A sample inlet for collecting fluids and/or gases, including oral fluids and expired breath samples, is connected to a container having a climate-controlled container reservoir. One or more sample containers are connected to the sample inlet for collection of samples. The devices are configured for safe transport and handling of samples, while maintaining sample viability, including for relatively long transport periods. Safety components integrated within the device facilitates safe and effective decontamination of contagious samples. In this manner, aborting the sample preservation by decontamination prior to a hazardous release is achieved within the same apparatus.
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公开(公告)号：US20240318202A1
公开(公告)日：2024-09-26
申请号：US18574777
申请日：2022-06-30
发明人： Arun Dhar , Arjoneel Dhar , Rod Russel R. Alenton
IPC分类号： C12N15/86 , C12N9/22 , C12N15/113
CPC分类号： C12N15/86 , C12N9/22 , C12N15/113 , C12N2310/20 , C12N2310/531 , C12N2770/30043
摘要： Described herein are engineered nodaviral vectors, systems, and uses thereof. In some embodiments, the engineered nodaviral vectors and/or systems can be used to deliver a cargo, such as a nucleic acid cargo, to a cell or cell population, or a subject. In some embodiments, the cargo is a therapeutic or preventative.
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公开(公告)号：US20240298949A1
公开(公告)日：2024-09-12
申请号：US18667395
申请日：2024-05-17
发明人： Eniko T. Enikov , Rein Anton , Gergo Edes , Brason R. Holt , Tyler B. Fowler , Miguel A. Osorio
CPC分类号： A61B5/227 , A61B5/742 , A61B2562/0247
摘要： A rectal tonometer device for quantitatively detecting and measuring a rectal tone of a patient. The device includes a main body including a cavity within and a deformable tip, including a pressure sensor, partially disposed in the cavity and extending from the main body. Deforming the tip may actuate the pressure sensor. The rectal tonometer device further includes a circuit board disposed within the cavity, communicatively coupled to the deformable tip capable of accepting a pressure signal from the pressure sensor and measuring, based on the pressure signal, the rectal tone of the patient.
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公开(公告)号：US12085632B2
公开(公告)日：2024-09-10
申请号：US17253023
申请日：2019-06-19
IPC分类号： G01N33/48 , G01N33/50 , G01R33/3415 , G01R33/36 , G01R33/565
CPC分类号： G01R33/56572 , G01R33/3415 , G01R33/3664
摘要： A method for producing a streak-suppressed magnetic resonance (MR) image of a subject includes generating an interference covariance matrix {circumflex over ( )}R front N coil images Ij (x,y), j={1, 2, . . . , N}, each of the N coil images Ij (x,y) corresponding to MR signals detected by a respective one of a phased array of N coils of an MRI scanner. The MR signals originate in voxels of the subject corresponding to an artifact-corrupted region of a coil image. Coordinates (x,y) correspond to a location within a cross-sectional plane of the subject. The method also includes, for subject-regions of cross-sectional plane centered at a respective location (x,y), determining a coil weight vector W (x,y) from {circumflex over ( )}R. The method also includes generating the streak-suppressed MR image as a weighted sum of the coil images Ij (x,y), each weight of the weighted sum being Wj* (x,y), a jth element of a complex conjugate of coil weight vector W (x,y).
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公开(公告)号：US20240295616A1
公开(公告)日：2024-09-05
申请号：US18712428
申请日：2022-11-22
发明人： Sasaan Showghi , Shelbi Jenkins
IPC分类号： G01R33/032 , G01R1/067 , G01R15/24
CPC分类号： G01R33/0322 , G01R1/06755 , G01R15/246 , G01R15/247
摘要： Methods, devices and systems are described that can be used to measure small magnetic fields, such as nano-Tesla and sub nano-Tesla magnetic fields. An example magnetometer includes a core having a photonic material that receives and maintains the propagation of polarized light. The magnetometer's cladding includes a polymer-based magneto-optic (MO) material in contact with the core which surrounds at least part of the core. The core and the cladding are configured to allow at least a portion of the polarized light to enter the cladding to interact with the polymer-based MO material in presence of an external magnetic field. Measurements of the light's polarization state after interaction with the polymer-based magneto-optic (MO) material enable a determination of a strength of the magnetic field.
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公开(公告)号：US20240294932A1
公开(公告)日：2024-09-05
申请号：US18553953
申请日：2022-04-05
发明人： Monica Schmidt
CPC分类号： C12N15/8243 , C12N9/58 , C12N15/8234
摘要： Maize is vital to both US agriculture and the economy. The US provides over half of the maize global market. In the US, field maize production is a $75B endeavor and comprises 95% of the total US grain production. Worldwide there is a net loss of 16 million tons of maize due to aflatoxin contamination. In the US alone, aflatoxin contamination of food/feed results in an estimated $52M-$1.68B agricultural loss every year. Aflatoxin contamination in crops, and subsequently livestock, threatens greater agricultural development, food security and human health. Elimination of aflatoxin is a critical economic and health issue in the US. The present invention features composition and methods for the degradation of aflatoxin in crops post-harvest.
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