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公开(公告)号：US09856447B2
公开(公告)日：2018-01-02
申请号：US14805267
申请日：2015-07-21
CPC分类号： C12M23/22 , C12M21/02 , C12M23/38 , C12M23/44 , C12M23/58 , C12M29/00 , C12M29/20 , C12M33/00 , C12M35/00 , C12M41/00 , C12M41/06 , C12M41/12 , C12M41/18 , C12M41/26 , C12M41/32 , C12M41/34 , C12M41/36 , C12M41/48
摘要： Methods and apparatus for culturing microorganisms are described, including culturing in mixotrophic culture conditions. A bioreactor array with multiple culture vessels with independently controllable inputs is used to culture similar cultures of microorganisms in which at least one parameter differs from other culture vessels in the bioreactor array.
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2.发明授权Direct transesterification of algal biomass for synthesis of fatty acid ethyl esters (FAEE) 有权用于合成脂肪酸乙酯（FAEE）的藻类生物质的直接酯交换公开(公告)号：US09187713B1
公开(公告)日：2015-11-17
申请号：US14804962
申请日：2015-07-21
发明人： Sandip Shinde
摘要： Methods of producing fatty acid ethyl esters (FAEE) using a direct transesterification process are described. The direct transesterification process uses low levels of chemical solvents, acid catalysts, and heating energy to produce the FAEE in a method with increased efficiency in a co-solvent system. The FAEE produced may be used in a variety of products including health, beauty, nutraceutical, and cosmetic products.
摘要翻译： 描述了使用直接酯交换方法生产脂肪酸乙酯（FAEE）的方法。 直接酯交换方法使用低水平的化学溶剂，酸催化剂和加热能量，以在共溶剂系统中提高效率的方法产生FAEE。 所生产的FAEE可用于各种产品，包括健康，美容，营养保健品和化妆品。
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3.发明授权公开(公告)号：US11134688B2
公开(公告)日：2021-10-05
申请号：US16878164
申请日：2020-05-19
发明人： Laura Carney , Edgard Jauregui , Michael Miller
摘要： Compositions and methods for indirectly reducing incidence of fungal pathogen infection in a plant are disclosed, wherein the fungal pathogen may be Botrytis, Macrophomina, Rhizoctonia, Sclerotinia, or Verticillium. The compositions comprise pasteurized microalgae cells in an amount effective to reduce incidence of the fungal pathogen in a plant compared to a substantially identical population of untreated plants. The composition treatment can include at least one microalgae such as Aurantiochytrium, Galdieria, Scenedesmus, Haematococcus, Isochrysis, Spirulina or any combination thereof.
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公开(公告)号：US10240120B2
公开(公告)日：2019-03-26
申请号：US14699659
申请日：2015-04-29
发明人： Eneko Ganuza Taberna , Jason D Licamele , Anna Lee Tonkovich , Michael V Bellefeuille , Cameron Wyatt , Thomas J Kulaga , Adriano Galvez, III
摘要： Methods of culturing mixotrophic microorganisms in a state of balanced gas composition are disclosed. Parameters of a culture of mixotrophic microorganisms may be controlled to reduce the requirements of externally supplied gases and optimize the production and consumption of gases within the culture by the phototrophic and heterotrophic metabolisms of the mixotrophic microorganisms.
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公开(公告)号：US09895403B2
公开(公告)日：2018-02-20
申请号：US15157047
申请日：2016-05-17
CPC分类号： A61K36/02 , A61K8/37 , A61K31/231 , A61Q19/00 , C11C3/003 , C12P7/6454
摘要： Methods of producing high purity palmitoleic acid esters from natural oils are disclosed. The natural oils may comprise plant oil, nut oil, microalgae oil, and fish oil. The methods of processing the natural oil comprise transesterification with ethanol as the reacting solvent to produce ethyl esters. Methods of producing a high purity fraction of Omega-3, 6, & 9 fatty acid esters from natural oils are also disclosed. The high purity fatty acid esters may be used in nutrition, cosmetic, and nutraceutical products.
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公开(公告)号：US09416347B2
公开(公告)日：2016-08-16
申请号：US14872448
申请日：2015-10-01
摘要： Methods of treating contamination, particularly bacterial contamination, in an open culture of microalgae with organic carbon are described herein. The methods comprise reducing the pH of a culture for a period of time and then raising the pH of the culture, wherein the culture comprises the presence of a first acid and the culture is contacted with a second acid to reduce the culture pH from a first pH value to a second pH value. The culture is maintained at the second pH value for at least 5 minutes before the culture pH is raised from the second pH value by contact with a base.
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公开(公告)号：US11109595B2
公开(公告)日：2021-09-07
申请号：US16333594
申请日：2017-09-15
IPC分类号： A01N63/00
摘要： The invention relates to compositions and methods for improving characteristics of plants and soil by administering an effective amount of a microalgae-based composition in low concentration applications.
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公开(公告)号：US11039622B2
公开(公告)日：2021-06-22
申请号：US16340005
申请日：2017-10-20
摘要： Methods of improving characteristics of plants and soil by administering an effective amount of a Kappaphycus based composition in low concentration applications are disclosed.
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9.发明授权公开(公告)号：US10357038B2
公开(公告)日：2019-07-23
申请号：US15536705
申请日：2015-12-16
摘要： Methods preparing a liquid mixotrophic Chlorella based composition comprising pasteurization and stabilization of a low concentration of mixotrophic Chlorella whole cells that have not been subjected to a drying process are disclosed. The liquid composition can be used to enhance the emergence and growth of plants in low concentration and low frequency soil and foliar applications.
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公开(公告)号：US10059918B2
公开(公告)日：2018-08-28
申请号：US15142964
申请日：2016-04-29
发明人： Luke Cizek , Mason Oelschlager , Justin Hayden , Miguel Olaizola , Mason McCarty , Richard Mazur
CPC分类号： C12N1/12 , C12M21/02 , C12M23/14 , C12M23/26 , C12M23/48 , C12M27/04 , C12M29/04 , C12M37/00 , C12M41/22 , C12M41/36 , C12M41/40
摘要： Some embodiments include a method. The method can include: inoculating a bioreactor with one or more first microorganisms and a first fluidic support medium, the bioreactor having one or more bioreactor walls at least partially enclosing a bioreactor cavity, being configured to be at least one of folded up or rolled up, and being sterile when the bioreactor is inoculated with the one or more first microorganisms, the one or more bioreactor walls having at least one bioreactor wall material, and the at least one bioreactor wall material being flexible and at least partially transparent; and vitally supporting the one or more first microorganisms with the bioreactor, a supply of light, and a supply of organic carbon. Other embodiments of related systems and methods are also disclosed.
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