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公开(公告)号：US12098166B2
公开(公告)日：2024-09-24
申请号：US17291924
申请日：2019-11-05
发明人： Egbert Siegfried Mundt , Xiaoping Cui , Zenglei Hu
IPC分类号： C07K14/005 , A61K9/00 , A61K39/00 , A61K39/145 , A61K39/39 , A61P31/16 , C12N7/00 , C12N15/86 , G01N33/569
CPC分类号： C07K14/005 , A61K9/0019 , A61K39/145 , A61K39/39 , A61P31/16 , C12N7/00 , C12N15/86 , G01N33/56983 , A61K2039/5252 , A61K2039/54 , A61K2039/545 , A61K2039/552 , A61K2039/55566 , C12N2710/14043 , C12N2760/16122 , C12N2760/16134 , C12N2760/16152 , C12N2760/16163 , C12N2760/16171 , G01N2333/11 , G01N2469/10
摘要： The invention relates to the field of veterinary medicine. The invention provides an immunogenic composition, comprising a hemagglutinin protein of avian influenza virus H5 subtype. Also provided is a method of differentiating animals naturally infected with AIV from animals vaccinated with the immunogenic composition of the invention. The immunogenic composition of the invention can provide a broader, more effective, long-lasting and early onset protection on poultry.
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2.发明公开公开(公告)号：US20240269105A1
公开(公告)日：2024-08-15
申请号：US18578205
申请日：2022-07-26
IPC分类号： A61K31/351 , A61K45/06 , A61P9/12
CPC分类号： A61K31/351 , A61K45/06 , A61P9/12
摘要： The present invention is directed to the use of one or more SGLT-2 inhibitors or pharmaceutically acceptable forms thereof for the prophylaxis and/or treatment of hypertension in a non-human mammal, preferably a carnivore, in particular a cat or a dog.
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![Substituted pyrrolo[1,2-b]pyridazines as anthelmintics](/abs-image/US/2024/06/04/US11999742B2/abs.jpg.150x150.jpg)
公开(公告)号：US11999742B2
公开(公告)日：2024-06-04
申请号：US18050567
申请日：2022-10-28
发明人： Hannes Fiepko Koolman , Bart Herlé
IPC分类号： A61K31/4985 , C07D237/26 , C07D487/04 , C07D491/052 , C07D513/04
CPC分类号： C07D487/04 , C07D491/052 , C07D513/04
摘要： This invention provides for compounds of the formula:
wherein the variables are defined herein, or salt thereof, compositions comprising these compounds, and methods for the treatment, control and/or prevention of a parasitic infestation and/or infection in an animal in need thereof by administering an effective amount of these compounds to said animal.-
公开(公告)号：USD1014779S1
公开(公告)日：2024-02-13
申请号：US29794875
申请日：2021-06-15
摘要： FIG. 1 is a front perspective view of an aerosol collector showing our new design;
FIG. 2 is a front elevational view thereof;
FIG. 3 is a back elevational view thereof;
FIG. 4 is a right side elevational view thereof;
FIG. 5 is a left side elevational view thereof;
FIG. 6 is a top plan view thereof;
FIG. 7 is a bottom plan view thereof; and,
FIG. 8 is a bottom perspective view thereof.
The broken lines in the drawings depict portions of the aerosol collector that form no part of the claimed design.-
公开(公告)号：US11896574B2
公开(公告)日：2024-02-13
申请号：US16805795
申请日：2020-03-01
发明人： Dania Birte Reiche , Silke Haag-Diergarten , Leah Jeanette Hennings , Saskia Kley , Anne M. Traas
IPC分类号： A61K31/351 , A61P3/10 , A61K38/28 , A61K31/7034 , C07D309/10 , C07H7/04 , A61K31/7042 , C07D493/10 , C07D493/08 , A61P3/06 , A61P31/12 , A61K31/357 , A61P9/12 , A61K31/381 , A61K31/7056 , C07H17/02 , C07D335/02 , A61K31/35 , A61K47/22 , C07D333/12 , A61P5/50 , A61P3/04 , C07H17/00 , C07H5/10 , A61P3/00 , C07H15/203 , A61P29/00 , C07D333/56
CPC分类号： A61K31/351 , A61K31/35 , A61K31/357 , A61K31/381 , A61K31/7034 , A61K31/7042 , A61K31/7056 , A61K38/28 , A61K47/22 , A61P3/00 , A61P3/04 , A61P3/06 , A61P3/10 , A61P5/50 , A61P9/12 , A61P29/00 , A61P31/12 , C07D309/10 , C07D333/12 , C07D333/56 , C07D335/02 , C07D493/08 , C07D493/10 , C07H5/10 , C07H7/04 , C07H15/203 , C07H17/00 , C07H17/02
摘要： The present invention relates to one or more SGLT2 inhibitors or pharmaceutically acceptable forms thereof for use in the treatment and/or prevention of a metabolic disorder in a feline animal, preferably wherein the metabolic disorder is one or more selected from the group consisting of: ketoacidosis, pre-diabetes, diabetes mellitus type 1 or type 2, insulin resistance, obesity, hyperglycemia, impaired glucose tolerance, hyperinsulinemia, dyslipidemia, dysadipokinemia, subclinical inflammation, systemic inflammation, low grade systemic inflammation, hepatic lipidosis, atherosclerosis, inflammation of the pancreas, neuropathy and/or Syndrome X (metabolic syndrome) and/or loss of pancreatic beta cell function and/or wherein the remission of the metabolic disorder, preferably diabetic remission, is achieved and/or maintained.
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公开(公告)号：US20230340028A1
公开(公告)日：2023-10-26
申请号：US18059171
申请日：2022-11-28
IPC分类号： C07K14/005 , C12N7/00 , C12N15/85 , A61P31/14 , A61K39/215
CPC分类号： C07K14/005 , C12N7/00 , C12N15/85 , A61P31/14 , A61K39/215 , C12N2770/20023 , C12N2770/20022 , C12N2800/10
摘要： The present invention relates i.a. to a recombinant avian coronavirus spike protein or fragment thereof comprising a mutation at amino acid position 267 to Cysteine. Further, the present invention relates to an immunogenic composition comprising an avian coronavirus with such spike protein.
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7.发明公开公开(公告)号：US20230277648A1
公开(公告)日：2023-09-07
申请号：US18067614
申请日：2022-12-16
发明人： Veljko NIKOLIN , Egbert Siegfried MUNDT , Fernando Rodriguez GONZALEZ , Laia Bosch CAMOS , Javier Alonso COLLADO MIGUENS
CPC分类号： A61K39/12 , C12N15/746 , C12N15/86 , A61K2039/552
摘要： The present invention relates to African swine fever virus (ASFV) peptides and/or polypeptides as well as immunogenic fragments thereof, corresponding encoding AFSV oligonucleotides and/or polynucleotides as well as immunogenic fragments thereof, immunogenic compositions, vaccines and uses thereof.
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公开(公告)号：US20230210394A1
公开(公告)日：2023-07-06
申请号：US18159241
申请日：2023-01-25
申请人： Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. , Boehringer Ingelheim Vetmedica GmbH
IPC分类号： A61B5/0255 , A61B5/00 , A61B7/04
CPC分类号： A61B5/0255 , A61B5/7264 , A61B7/04 , A61B2503/40
摘要： A method for analyzing an acoustic signal having a time period and having a plurality of repeated audio patterns, has the following steps: receiving an audio signal having the acoustic signal; determining the audio patterns repeated within the acoustic signal; determining a window length for a plurality of windows, wherein the window length divides the time period of the acoustic signal into the plurality of windows; and windowing the acoustic signal to obtain the plurality of windows.
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公开(公告)号：US11679212B2
公开(公告)日：2023-06-20
申请号：US16101617
申请日：2018-08-13
发明人： Marcus Knell , Michael Aven , Benjamin Franzmann , Steffen Schuy , Herbert Wachtel , Guido Endert , Alexander Christ , Horst Wergen
CPC分类号： A61M15/08 , A61D7/04 , A61M15/009 , A61M15/0013 , A61M15/0073 , A61M15/0086 , A61M15/0093 , A61M15/0096 , B05B11/1056 , A61M15/0018 , A61M2205/581 , A61M2205/583 , A61M2250/00 , B05B7/0012 , B05B11/0038 , B05B11/1091
摘要： An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with a pressure generator, which has a tensioning device for the drive, and with a tensioning mechanism for tensioning the tensioning device, whereby the tensioning mechanism has a lever gear for tensioning the tensioning device.
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公开(公告)号：US20230159543A1
公开(公告)日：2023-05-25
申请号：US18050567
申请日：2022-10-28
发明人： Hannes Fiepko KOOLMAN , Bart HERLÉ
IPC分类号： C07D487/04 , C07D513/04 , C07D491/052
CPC分类号： C07D487/04 , C07D513/04 , C07D491/052
摘要： This invention provides for compounds of the formula:
wherein the variables are defined herein, or salt thereof, compositions comprising these compounds, and methods for the treatment, control and/or prevention of a parasitic infestation and/or infection in an animal in need thereof by administering an effective amount of these compounds to said animal.
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