公开(公告)号：US20150150365A1

公开(公告)日：2015-06-04

申请号：US14541110

申请日：2014-11-13

申请人： CHENG FANG ,  JUI-HUNG SU

发明人： CHENG FANG ,  JUI-HUNG SU

IPC分类号： A46B3/00 ,  A46D3/00 ,  A46B9/02

CPC分类号： A46B3/005 ,  A46B9/028 ,  A46B9/04 ,  A46B2200/1066 ,  A46D3/005

摘要： An integral brush is formed by performing steps of tufts arrangement, tufts insertion into mold, mold turning and closing, and injection molding, thereby forming no gaps between cleaning assembly and handle. The cleaning assembly includes at least one cleaning unit each having a plurality of tufts integrally formed with one of a plurality of bases in the handle. The tufts are spaced apart and an upper portion of each tuft is shaped to form an uneven tip. The brush can increase a contact area between the cleaning assembly and an object so as to effectively clean the object.

摘要翻译： 通过执行刷毛簇布置，刷毛束插入模具，模具转动和关闭以及注射成型中的步骤形成整体刷子，从而在清洁组件和手柄之间形成间隙。 清洁组件包括至少一个清洁单元，每个清洁单元具有与手柄中的多个基座中的一个一体形成的多个刷毛簇。 毛簇间隔开，并且每个簇的上部被成形以形成不均匀的尖端。 刷子可以增加清洁组件和物体之间的接触面积，以便有效地清洁物体。

公开(公告)号：US08705326B2

公开(公告)日：2014-04-22

申请号：US13900186

申请日：2013-05-22

申请人： Ko Cheng Fang

发明人： Ko Cheng Fang

IPC分类号： G11B11/00

CPC分类号： G11B7/24097 ,  G11B20/00608 ,  G11B20/00927 ,  G11B23/281

摘要： A copy protection method includes the steps of providing an optical storage device having a substrate layer and a data structure layer coated on the substrate layer and containing a set of raw data codes; forming on the data structure layer at least one polarizing layer capable of causing a change in a light beam; and forming on the polarizing layer a scratch protection layer. The polarizing layer is located between the data structure layer and an optical reading device to influence a light beam irradiated thereon by the optical reading device, so that the set of raw data codes being optically accessed is conditionally converted into a different set of physical data codes. By providing the polarizing layer on the optical storage device to change the data codes that can be obtained by the optical reading device, it is able to stop illegal copying of the optical storage device.

摘要翻译： 复制保护方法包括以下步骤：提供具有衬底层和涂覆在衬底层上的数据结构层并包含一组原始数据代码的光学存储器件; 在数据结构层上形成能够引起光束变化的至少一个偏振层; 并在偏振层上形成刮擦保护层。 偏光层位于数据结构层和光学读取装置之间，以影响由光学读取装置照射的光束，使得光学访问的原始数据代码组有条件地转换成不同的物理数据代码集 。 通过在光存储装置上设置偏振层来改变由光学读取装置获得的数据代码，能够停止光存储装置的非法拷贝。

公开(公告)号：US20140066609A1

公开(公告)日：2014-03-06

申请号：US13604353

申请日：2012-09-05

申请人： Kuei-Lin LU ,  Yu CHANG ,  Cheng-Fang HSU ,  Mei-Hui WANG ,  Wuu-Jyh LIN

发明人： Kuei-Lin LU ,  Yu CHANG ,  Cheng-Fang HSU ,  Mei-Hui WANG ,  Wuu-Jyh LIN

IPC分类号： C07H15/04

CPC分类号： C07H15/04 ,  C07H1/00 ,  Y02P20/55

摘要： A novel synthesis method of Glyco-drug radiotracer precursor is revealed. After completing synthesis of Z-Gly-ah (main structure), galactosamine GalNAc(OAc)4 is added to have coupling reaction. Then a product is separated directly from dichloromethane. Thus loss of galactosamine during extraction with liquid chromatography is reduced. Moreover, instead of trifluoroacetyl group, carbobenzoxy (abbreviated as Cbz or Z) is used as a protecting group to ensure uniformity of the phase. The cost and synthesis time are also dramatically reduced.

摘要翻译： 揭示了一种新型的糖 - 放射性示踪剂前体的合成方法。 完成Z-Gly-ah（主要结构）合成后，加入半乳糖胺GalNAc（OAc）4进行偶联反应。 然后将产物直接从二氯甲烷中分离出来。 因此，用液相色谱法提取过程中半乳糖胺的损失降低。 此外，代替三氟乙酰基，使用苄氧羰基（缩写为Cbz或Z）作为保护基，以确保相的均匀性。 成本和合成时间也大大降低。

公开(公告)号：US08589569B2

公开(公告)日：2013-11-19

申请号：US11517200

申请日：2006-09-06

申请人： Cheng-Fang Lin ,  Samit Roy

发明人： Cheng-Fang Lin ,  Samit Roy

IPC分类号： G06F17/30

CPC分类号： G06F17/30421 ,  G06F17/30528

摘要： One embodiment of the present invention provides a system stored on a non-transitory computer-readable storage medium for invoking a plug-in that is dynamically associated with a database operation. During operation, a client sends a request to a database system to perform an operation on the database, wherein the request includes a control-message which specifies a plug-in which needs to be executed. Next, the system executes the plug-in at a plug-in server to obtain a plug-in result. Then, the system determines if the plug-in result is an error identifier. If so, the system sends the error identifier to the client. On the other hand, if the plug-in result is not an error identifier, the system performs the operation to obtain an operation result. The system then sends the operation result to the client.

摘要翻译： 本发明的一个实施例提供了一种存储在非暂时计算机可读存储介质上的系统，用于调用与数据库操作动态相关联的插件。 在操作期间，客户端向数据库系统发送请求以对数据库执行操作，其中请求包括指定需要执行的插件的控制消息。 接下来，系统在插件服务器上执行插件以获得插件结果。 然后，系统确定插件结果是否是错误标识符。 如果是这样，系统会向客户端发送错误标识符。 另一方面，如果插件结果不是错误标识符，则系统执行操作以获得操作结果。 系统然后将操作结果发送给客户端。

公开(公告)号：US08551447B2

公开(公告)日：2013-10-08

申请号：US13087664

申请日：2011-04-15

申请人： Show-Wen Liu ,  Cheng-Hsien Lin ,  Yu Chang ,  Cheng-Fang Hsu ,  Tsyh-Lang Lin

发明人： Show-Wen Liu ,  Cheng-Hsien Lin ,  Yu Chang ,  Cheng-Fang Hsu ,  Tsyh-Lang Lin

IPC分类号： A61K38/00

CPC分类号： C07H15/04

摘要： A bifunctional compound with a monosaccharide and a N2S2 ligand, and more particularly, a bifunctional compound with a N2S2 ligand and aminohexylacetyl galactosamine (ah-GalNAc4) is provided. A method for preparing the bifunctional compound with a monosaccharide and a N2S2 ligand is also provided, including activating a carboxyl group in an organic ligand, reacting the activated carboxyl group with a galactopyranoside through amidation, and then hydrolyzing. The bifunctional compound of the present invention is widely useful in nuclear medicine for preparation of liver imaging agents for assisting in correct diagnosis of diseases.

摘要翻译： 提供了具有单糖和N2S2配体的双官能化合物，更具体地，提供了具有N 2 S 2配体和氨基己基乙酰基半乳糖胺（ah-GalNAc 4）的双官能化合物。 还提供了用单糖和N 2 S 2配体制备双功能化合物的方法，包括活化有机配体中的羧基，通过酰胺化使活化的羧基与吡喃半乳糖苷反应，然后水解。 本发明的双功能化合物在制备用于辅助正确诊断疾病的肝成像剂的核医学中广泛有用。

公开(公告)号：US08550345B2

公开(公告)日：2013-10-08

申请号：US12120909

申请日：2008-05-15

申请人： Cheng-Fang Huang ,  Pin-Hsun Huang ,  Chih-Hsiang Wang ,  Wen-Cheng Hsu ,  Yi-fang cho ,  An-Hong Liu ,  Yi-Chang Lee

发明人： Cheng-Fang Huang ,  Pin-Hsun Huang ,  Chih-Hsiang Wang ,  Wen-Cheng Hsu ,  Yi-fang cho ,  An-Hong Liu ,  Yi-Chang Lee

IPC分类号： G06F19/00

CPC分类号： G06Q10/08

摘要： This invention provides an RFID real-time information system accommodated to a semiconductor supply chain for exchanging real-time information. The RFID real-time information system is characterized by comprising an RFID middleware module for generating a stock and logistic information corresponding to a plurality of carriers and wafers from a tag information; a manufacturing information module for storing an object information corresponding to the plurality of wafers; a real-time information module for integrating the RFID middleware module with the manufacturing information module to generate real-time information corresponding to the plurality of wafers and carriers; and a business-to-business (B2B) e-commerce module comprising a plurality of B2B servers respectively disposed in vendors in the semiconductor supply chain for connecting and exchanging the real-time information through a standard protocol of e-commerce.

摘要翻译： 本发明提供一种适用于半导体供应链的RFID实时信息系统，用于交换实时信息。 RFID实时信息系统的特征在于包括：RFID中间件模块，用于从标签信息生成对应于多个载体和晶片的库存和物流信息; 制造信息模块，用于存储对应于所述多个晶片的对象信息; 实时信息模块，用于将RFID中间件模块与制造信息模块集成，以生成与多个晶片和载体对应的实时信息; 以及分别设置在半导体供应链的供应商中的多个B2B服务器的企业对企业（B2B）电子商务模块，用于通过电子商务的标准协议来连接和交换实时信息。

公开(公告)号：US08349738B2

公开(公告)日：2013-01-08

申请号：US13293878

申请日：2011-11-10

申请人： Clement Lansalot-Matras ,  Christian Dussarrat ,  Vincent M. Omarjee ,  Cheng-Fang Hsiao

发明人： Clement Lansalot-Matras ,  Christian Dussarrat ,  Vincent M. Omarjee ,  Cheng-Fang Hsiao

IPC分类号： H01L21/44

CPC分类号： H01L21/28562 ,  C23C16/18 ,  C23C16/45536 ,  C23C16/45553 ,  H01L21/76871

摘要： Compositions and methods for forming a metal-containing thin film on a substrate. A reactor and at least one substrate in the reactor are provided. A metal-containing bis-β-diketiminate precursor is introduced into the reactor. The reactor is maintained at a set temperature and pressure, and the precursor is contacted with the substrate to form a metal-containing film on the substrate.

摘要翻译： 在基材上形成含金属薄膜的组合物和方法。 提供反应器和反应器中的至少一个基板。 将含金属的双 - 二氮嗪酮前体引入反应器。 将反应器保持在设定的温度和压力下，并将前体与基底接触以在基底上形成含金属的膜。

公开(公告)号：US08329879B2

公开(公告)日：2012-12-11

申请号：US12558911

申请日：2009-09-14

申请人： Show-Wen Liu ,  Cheng-Hsien Lin ,  Tsyh-Lang Lin ,  Cheng-Fang Hsu

发明人： Show-Wen Liu ,  Cheng-Hsien Lin ,  Tsyh-Lang Lin ,  Cheng-Fang Hsu

IPC分类号： C07F13/00

CPC分类号： C07C323/41 ,  C07F13/005

摘要： H3LMN series compounds used as radioactive agents for treatment of liver cancer and a manufacturing method thereof are revealed. 2-thioethylamine hydrochloride is reacted with triphenylmethanol for protection of thiol to obtain 2-[(triphenylmethyl)thio]ethylamine. Then obtain N-[2-((triphenylmethyl)thio)ethyl]chloroacetamide by a transamidation reaction between 2-[(triphenylmethyl)thio]ethylamine and chloroactyl chloride. Next produce a amine-amide-thiol ligand-N-[2-((triphenylmethyl)thio)ethyl][2-((triphenylmethyl)thio)ethylamino]acetamide by a substitution reaction of N-[2-((triphenylmethyl)thio)ethyl]chloroacetamide and 2-[(triphenylmethyl)thio]ethylamine. After respective reaction with 1-bromotetradecane, 1-bromohexadecane and ethyl 16-bromohexadecanoate, H3LMN series compounds are obtained. These amine-amide-dithiols quadridentate ligands can react with MO3+ (M=Tc or Re) to produce electrically neutral complexes. The complexes have high lipophilicity, allowing them soluble in lipiodol to be applied to radiation therapy for liver cancer.

摘要翻译： 揭示了用作肝癌治疗放射剂的H3LMN系列化合物及其制造方法。 将2-硫代乙胺盐酸盐与三苯基甲醇反应以保护硫醇，得到2 - [（三苯基甲基）硫代]乙胺。 然后通过2 - [（三苯基甲基）硫代]乙胺和氯代酰氯的酰胺化反应获得N- [2 - （（三苯基甲基）硫基）乙基]氯乙酰胺。 接着通过N- [2 - （（三苯基甲基）硫代）的取代反应生成胺 - 酰胺 - 硫醇配体-N- [2 - （（三苯基甲基）硫代）乙基] [2 - （（三苯基甲基）硫基）乙基氨基] ）乙基]氯乙酰胺和2 - [（三苯甲基）硫基]乙胺。 在与1-溴十四烷，1-溴十六烷和16-溴十六烷酸乙酯反应后，得到H3LMN系列化合物。 这些胺 - 酰胺 - 二硫醇三元配体可以与MO3 +（M = Tc或Re）反应以产生电中性络合物。 复合物具有高亲脂性，使其可溶于碘油以适用于放射治疗肝癌。

公开(公告)号：US20120122313A1

公开(公告)日：2012-05-17

申请号：US13293878

申请日：2011-11-10

申请人： Christian Dussarrat ,  Clement Lansalot-Matras ,  Vincent M. Omarjee ,  Cheng-Fang Hsiao

发明人： Christian Dussarrat ,  Clement Lansalot-Matras ,  Vincent M. Omarjee ,  Cheng-Fang Hsiao

IPC分类号： H01L21/3205

CPC分类号： H01L21/28562 ,  C23C16/18 ,  C23C16/45536 ,  C23C16/45553 ,  H01L21/76871

摘要： Compositions and methods for forming a metal-containing thin film on a substrate. A reactor and at least one substrate in the reactor are provided. A metal-containing bis-β-diketiminate precursor is introduced into the reactor. The reactor is maintained at a set temperature and pressure, and the precursor is contacted with the substrate to form a metal-containing film on the substrate.

摘要翻译： 在基材上形成含金属薄膜的组合物和方法。 提供反应器和反应器中的至少一个基板。 将含金属的双 - 二氮嗪酮前体引入反应器。 将反应器保持在设定的温度和压力下，并将前体与基底接触以在基底上形成含金属的膜。

公开(公告)号：US08048405B2

公开(公告)日：2011-11-01

申请号：US12354815

申请日：2009-01-16

申请人： Tsai-Yueh Luo ,  I-Chung Tang ,  Show-Wen Liu ,  Yu-Lung Wu ,  Cheng-Hsien Lin ,  Cheng-Fang Hsu ,  Kwei-Luen Hsu ,  Chang-Mau Sheng ,  Ching-Jun Liou ,  Te-Sheng Liang

发明人： Tsai-Yueh Luo ,  I-Chung Tang ,  Show-Wen Liu ,  Yu-Lung Wu ,  Cheng-Hsien Lin ,  Cheng-Fang Hsu ,  Kwei-Luen Hsu ,  Chang-Mau Sheng ,  Ching-Jun Liou ,  Te-Sheng Liang

IPC分类号： A61K49/00

CPC分类号： A61K51/0478 ,  A61K49/0438

摘要： A radioactive mixture and a manufacturing method thereof are disclosed. The radioactive mixture (188Re-MN/Lipiodol mixture) is formed by chelating reaction of MN series compounds that are amine-amide-disulfide amine quadric-dentate chelate ligands with TcO4−/or ReO4−, and then dissolved in Lipiodol. Moreover, the 99mTc/or 188Re of the TcO4−/or ReO4− avoids bone marrow injuries caused by free 90Y. By the feature of the Lipiodol that stays in liver tumors for a long period, the radioactive mixture is applied to treat liver cancers by injection so that injuries caused by surgical operations can be prevented. 188Re-MN/Lipiodol is used for liver cancer, breast cancer or other solid tumors treatment. Re-188 MN or Re-188 MN/Lipiodol can be mixed with anticancer drugs, hydrogel, liposome, micelle or other nano-particles to form the multifunctional therapeutic modality.

摘要翻译： 公开了放射性混合物及其制造方法。 通过胺胺 - 二硫化胺胺二齿螯合配体的MN系列化合物与TcO4-或ReO4-螯合反应形成放射性混合物（188Re-MN / Lipiodol混合物），然后溶于Lipiodol中。 此外，TcO4- /或ReO4的99mTc /或188Re避免了由自由90Y引起的骨髓损伤。 通过长时间停留在肝肿瘤中的碘碘醇的特征，通过注射施用放射性混合物来治疗肝癌，从而可以预防外科手术引起的损伤。 188Re-MN / Lipiodol用于肝癌，乳腺癌或其他实体瘤治疗。 Re-188 MN或Re-188 MN / Lipiodol可与抗癌药物，水凝胶，脂质体，胶束或其他纳米颗粒混合，形成多功能治疗方式。