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    MULTI-STREAM SPECTROPHOTOMETER MODULE
    2.
    发明申请
    MULTI-STREAM SPECTROPHOTOMETER MODULE 失效
    多流分光光度计模块

    公开(公告)号：US20120207650A1

    公开(公告)日：2012-08-16

    申请号：US13499757

    申请日：2010-10-08

    Applicant: Robin Fortt ,  Colin Steel ,  Victor D. Samper ,  Marko Baller

    Inventor： Robin Fortt ,  Colin Steel ,  Victor D. Samper ,  Marko Baller

    IPC: B01J19/00 ,  G01N1/10 ,  G01J3/00

    CPC classification number: G01N30/74 ,  G01N21/05 ,  G01N21/33 ,  G01N21/85 ,  G01N30/466 ,  G01N30/88 ,  G01N2021/0321 ,  G01N2021/0346 ,  G01N2021/0357 ,  G01N2030/746 ,  G01N2030/8868 ,  G01N2030/8881 ,  G21H5/02

    Abstract: A multi-stream optical interrogation flow cell (60) for a radiopharmaceutical includes a multiple flow cell body (10a-f) defining a first elongate fluid flowpath (A1-6;B1-6) therethrough for individually conducting a radiopharmaceutical therethrough in fluid isolation from other of the flow cell bodies. Each flow cell body further defines a first and second aligned UV transparent optical guides (36,38) and a first interrogation passageway (26a-f) extending between the first and second optical guides such that a portion of the elongate first fluid flowpath intersects the interrogation passageway such that the radiopharmaceutical flows in between the first and second optical guides. The first and second interrogation passageways of all of the flow cell bodies are optically aligned so that a single interrogation beam is able to extend through each of the interrogation passageways.

    Abstract translation: 用于放射性药物的多流光学询问流动池（60）包括限定通过其的第一细长流体流动路径（A1-6; B1-6）的多流通池体（10a-f），用于在流体隔离中单独地导入放射性药物 来自其他流动池体。 每个流动池主体还限定第一和第二对准的UV透明光导（36,38）和在第一和第二光导之间延伸的第一询问通道（26a-f），使得细长的第一流体流路的一部分与 询问通道，使得放射性药物在第一和第二光导之间流动。 所有流动池体的第一和第二询问通路是光学对准的，使得单个询问光束能够延伸通过询问通道中的每一个。

    MULTI-STREAM HIGH-PRESSURE LIQUID CHROMATOGRAPHY MODULE
    3.
    发明申请
    MULTI-STREAM HIGH-PRESSURE LIQUID CHROMATOGRAPHY MODULE 有权
    多级高压液相色谱模块

    公开(公告)号：US20120193555A1

    公开(公告)日：2012-08-02

    申请号：US13499775

    申请日：2010-10-08

    Applicant: Colin Steel ,  Farah Shah ,  Sajinder Luthra

    Inventor： Colin Steel ,  Farah Shah ,  Sajinder Luthra

    IPC: G01N21/85 ,  B01D15/18

    CPC classification number: G01N30/74 ,  G01N21/05 ,  G01N21/33 ,  G01N21/85 ,  G01N30/466 ,  G01N30/88 ,  G01N2021/0321 ,  G01N2021/0346 ,  G01N2021/0357 ,  G01N2030/746 ,  G01N2030/8868 ,  G01N2030/8881 ,  G21H5/02

    Abstract: An HPLC module utilizes a combination of compound-dedicated hardware providing line clearance between differing radiosynthesis and includes multiple compound-dedicated HPLC inject valves, each inject valve directing a fluid to a serially-connected HPLC column and UV flowcell so as to prevent cross-contamination between differing radiopharmaceutical syntheses. The module provides a disposable fluid path from each UV flowcell allowing for radioactive detection, fraction collection, formulation and final product dispensing. In this manner, a level of GMP compliance is achieved that is suitable for meeting the requirements of an MHRA approved site-license.

    Abstract translation: HPLC模块利用化合物专用硬件的组合，在不同的放射合成之间提供线间隙，并且包括多个复合专用HPLC注射阀，每个注射阀将流体引导到串联的HPLC柱和UV流通池，以防止交叉污染 在不同的放射性药物合成之间。 该模块提供来自每个UV流通池的一次性流体路径，允许放射性检测，馏分收集，配制和最终产品分配。 以这种方式，达到符合MHRA认证的站点许可证要求的符合GMP标准。

    SYSTEM FOR DISPENSING A FLUID IN NON-CONTROLLED ENVIRONMENTS
    4.
    发明申请
    SYSTEM FOR DISPENSING A FLUID IN NON-CONTROLLED ENVIRONMENTS 审中-公开
    用于在非控制环境中分配流体的系统

    公开(公告)号：US20110094619A1

    公开(公告)日：2011-04-28

    申请号：US12864667

    申请日：2009-02-09

    Applicant: Colin Steel ,  Roger Pettitt ,  Paul Crosby ,  Svein-Erik Lindgaard

    Inventor： Colin Steel ,  Roger Pettitt ,  Paul Crosby ,  Svein-Erik Lindgaard

    IPC: B67C3/02 ,  B65D71/00 ,  F16B2/20

    CPC classification number: B65B3/003 ,  B65B3/12 ,  B65B55/02 ,  G21F5/015 ,  Y10T24/44017

    Abstract: The present invention provides a dispenser cassette (110) which provides at least one product dispense vial (122) to be filled. The cassette provides a filtrate conduit (128) extending between the dispense vial and a filter unit (116) so that flowpath (120) of the filtrate conduit and the dispense vial is provided and maintained as an environmentally-controlled, or GMP-compliant, volume. The resulting product dispensed into the dispense vial is thus dispensed in a GMP-compliant environment.

    Abstract translation: 本发明提供了一种分配器盒（110），其提供待填充的至少一个产品分配小瓶（122）。 所述盒提供在所述分配小瓶和过滤器单元（116）之间延伸的滤液导管（128），使得所述滤液导管和所述分配小瓶的流路（120）被提供并保持为环境受控或符合GMP的， 卷。 因此，分配到分配小瓶中的所得产品在符合GMP的环境中被分配。

    Multi-stream spectrophotometer module
    8.
    发明授权
    Multi-stream spectrophotometer module 失效
    多流分光光度计模块

    公开(公告)号：US08664617B2

    公开(公告)日：2014-03-04

    申请号：US13499757

    申请日：2010-10-08

    Applicant: Robin Fortt ,  Colin Steel ,  Victor D. Samper ,  Marko Baller

    Inventor： Robin Fortt ,  Colin Steel ,  Victor D. Samper ,  Marko Baller

    IPC: G01J1/42

    CPC classification number: G01N30/74 ,  G01N21/05 ,  G01N21/33 ,  G01N21/85 ,  G01N30/466 ,  G01N30/88 ,  G01N2021/0321 ,  G01N2021/0346 ,  G01N2021/0357 ,  G01N2030/746 ,  G01N2030/8868 ,  G01N2030/8881 ,  G21H5/02

    Abstract: A multi-stream optical interrogation flow cell (60) for a radiopharmaceutical includes a multiple flow cell body (10a-f) defining a first elongate fluid flowpath (A1-6;B1-6) therethrough for individually conducting a radiopharmaceutical therethrough in fluid isolation from other of the flow cell bodies. Each flow cell body further defines a first and second aligned UV transparent optical guides (36,38) and a first interrogation passageway (26a-f) extending between the first and second optical guides such that a portion of the elongate first fluid flowpath intersects the interrogation passageway such that the radiopharmaceutical flows in between the first and second optical guides. The first and second interrogation passageways of all of the flow cell bodies are optically aligned so that a single interrogation beam is able to extend through each of the interrogation passageways.

    Abstract translation: 用于放射性药物的多流光学询问流动池（60）包括限定通过其的第一细长流体流动路径（A1-6; B1-6）的多流通池体（10a-f），用于在流体隔离中单独地导入放射性药物 来自其他流动池体。 每个流动池主体还限定第一和第二对准的UV透明光导（36,38）和在第一和第二光导之间延伸的第一询问通道（26a-f），使得细长的第一流体流路的一部分与 询问通道，使得放射性药物在第一和第二光导之间流动。 所有流动池体的第一和第二询问通路是光学对准的，使得单个询问光束能够延伸通过询问通道中的每一个。

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