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公开(公告)号：US08753587B2
公开(公告)日：2014-06-17
申请号：US13514132
申请日：2010-12-30
申请人： Victor Samper , Christian Rensch , Christoph Boeld , Marko Baller
发明人： Victor Samper , Christian Rensch , Christoph Boeld , Marko Baller
IPC分类号： B01D21/00
CPC分类号： F16K99/0001 , F16K99/0015 , F16K2099/008
摘要： A microvalve assembly (10) includes an elongate valve body (14) having opposed first and second major surfaces, the first major surface defining a valve recess (34) and the second major surface defining first and second fluid ports (20,22). Both the fluid input port and the fluid output port extend in fluid communication with the valve recess. A gasket (12) is freely positioned within the valve recess so as to extend in overlying registry with either or both of fluid ports. A valve cover (16) is bonded to the valve body and includes a first planar surface positioned in overlying registry with the valve recess so as to enclose the gasket therein. The valve cover is deflectable into the valve recess so as to cause the gasket to seal at least one of the fluid ports.
摘要翻译： 微阀组件（10）包括具有相对的第一和第二主表面的细长阀体（14），所述第一主表面限定阀凹部（34），所述第二主表面限定第一和第二流体端口（20,22）。 流体输入端口和流体输出端口都与阀门凹口流体连通地延伸。 垫片（12）自由地定位在阀凹部内，以便在任一个或两个流体端口的上面对准中延伸。 阀盖（16）与阀体结合并且包括位于与阀凹部对齐的第一平坦表面，以便将垫圈包围在其中。 阀盖可偏转到阀门凹口中，以便使垫圈密封至少一个流体端口。
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公开(公告)号：US08664617B2
公开(公告)日：2014-03-04
申请号：US13499757
申请日：2010-10-08
申请人： Robin Fortt , Colin Steel , Victor D. Samper , Marko Baller
发明人： Robin Fortt , Colin Steel , Victor D. Samper , Marko Baller
IPC分类号： G01J1/42
CPC分类号： G01N30/74 , G01N21/05 , G01N21/33 , G01N21/85 , G01N30/466 , G01N30/88 , G01N2021/0321 , G01N2021/0346 , G01N2021/0357 , G01N2030/746 , G01N2030/8868 , G01N2030/8881 , G21H5/02
摘要： A multi-stream optical interrogation flow cell (60) for a radiopharmaceutical includes a multiple flow cell body (10a-f) defining a first elongate fluid flowpath (A1-6;B1-6) therethrough for individually conducting a radiopharmaceutical therethrough in fluid isolation from other of the flow cell bodies. Each flow cell body further defines a first and second aligned UV transparent optical guides (36,38) and a first interrogation passageway (26a-f) extending between the first and second optical guides such that a portion of the elongate first fluid flowpath intersects the interrogation passageway such that the radiopharmaceutical flows in between the first and second optical guides. The first and second interrogation passageways of all of the flow cell bodies are optically aligned so that a single interrogation beam is able to extend through each of the interrogation passageways.
摘要翻译： 用于放射性药物的多流光学询问流动池（60）包括限定通过其的第一细长流体流动路径（A1-6; B1-6）的多流通池体（10a-f），用于在流体隔离中单独地导入放射性药物 来自其他流动池体。 每个流动池主体还限定第一和第二对准的UV透明光导（36,38）和在第一和第二光导之间延伸的第一询问通道（26a-f），使得细长的第一流体流路的一部分与 询问通道，使得放射性药物在第一和第二光导之间流动。 所有流动池体的第一和第二询问通路是光学对准的，使得单个询问光束能够延伸通过询问通道中的每一个。
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公开(公告)号：US20120184722A1
公开(公告)日：2012-07-19
申请号：US13499744
申请日：2010-10-08
申请人： Victor Samper , Marko Baller , Emiliano De Marco , Xavier Franci , Philippe DuMont , Sali Kuci , Colin Steel , Robin Fortt
发明人： Victor Samper , Marko Baller , Emiliano De Marco , Xavier Franci , Philippe DuMont , Sali Kuci , Colin Steel , Robin Fortt
CPC分类号： G01N30/74 , G01N21/05 , G01N21/33 , G01N21/85 , G01N30/466 , G01N30/88 , G01N2021/0321 , G01N2021/0346 , G01N2021/0357 , G01N2030/746 , G01N2030/8868 , G01N2030/8881 , G21H5/02
摘要： Disposable components for a separation and purification system include a flow cell, an end cap for a chromatography column, and a chromatography column useful for medium-pressure liquid chromatography (MPLC).
摘要翻译： 用于分离和纯化系统的一次性组分包括流动池，色谱柱的端盖和用于中压液相色谱（MPLC）的色谱柱。
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公开(公告)号：US20080239306A1
公开(公告)日：2008-10-02
申请号：US11693277
申请日：2007-03-29
申请人： William Scott Sutherland , Anis Zribi , Long Que , Glenn Scott Claydon , Stacey Joy Kennerly , Ayan Banerjee , Shivappa Ningappa Goravar , Shankar Chandrasekaran , David Cecil Hays , Victor Samper , Dirk Lange , Marko Baller , Min-Yi Shih , Sandip Maity
发明人： William Scott Sutherland , Anis Zribi , Long Que , Glenn Scott Claydon , Stacey Joy Kennerly , Ayan Banerjee , Shivappa Ningappa Goravar , Shankar Chandrasekaran , David Cecil Hays , Victor Samper , Dirk Lange , Marko Baller , Min-Yi Shih , Sandip Maity
CPC分类号： G01N21/65 , G01J3/02 , G01J3/0208 , G01J3/021 , G01J3/0218 , G01J3/0232 , G01J3/0237 , G01J3/027 , G01J3/0289 , G01J3/10 , G01J3/1895 , G01J3/44 , G02B26/02 , G02B26/0808 , G02B26/0816
摘要： A system and method for managing optical power for controlling thermal alteration of a sample undergoing spectroscopic analysis is provided. The system includes a moveable laser beam generator for irradiating the sample and a beam shaping device for moving and shaping the laser beam to prevent thermal overload or build up in the sample. The moveable laser beam generator includes at least one beam shaping device selected from the group consisting of at least one optical lens, at least one optical diffractor, at least one optical path difference modulator, at least one moveable mirror, at least one Micro-Electro-Mechanical Systems (MEMS) integrated circuit (IC), and/or a liquid droplet. The system also includes an at least two degree of freedom (2 DOF) moveable substrate platform and a controller for controlling the laser beam generator and the substrate platform, and for analyzing light reflected from the sample.
摘要翻译： 提供了一种用于管理用于控制进行光谱分析的样品的热变化的光功率的系统和方法。 该系统包括用于照射样品的可移动激光束发生器和用于移动和成形激光束的光束整形装置，以防止样品中的热过载或积聚。 可移动激光束发生器包括至少一个光束成形装置，其选自由至少一个光学透镜，至少一个光学衍射器，至少一个光程差调制器，至少一个可动反射镜，至少一个微电极 机电系统（MEMS）集成电路（IC）和/或液滴。 该系统还包括至少两个自由度（2自由度）可移动基板平台和用于控制激光束发生器和基板平台的控制器，并用于分析从样品反射的光。
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公开(公告)号：US09455055B2
公开(公告)日：2016-09-27
申请号：US13377881
申请日：2010-07-12
申请人： Marko Baller , Victor Samper , Christian Rensch , Christoph Boeld
发明人： Marko Baller , Victor Samper , Christian Rensch , Christoph Boeld
CPC分类号： G21G1/001 , G21G2001/0015
摘要： Devices and methods for electrochemical phase transfer utilize at least one electrode formed from either glassy carbon or a carbon and polymer composite. The device includes a device housing defining an inlet port (42), an outlet port (44) and an elongate fluid passageway (36) extending therebetween. A capture electrode (12) and a counter electrode are positioned within said housing such that the fluid passageway extends between the capture and counter electrodes.
摘要翻译： 用于电化学相转移的装置和方法利用由玻璃碳或碳和聚合物复合材料形成的至少一个电极。 该装置包括限定入口端口（42），出口端口（44）和在其间延伸的细长流体通道（36）的装置壳体。 捕获电极（12）和对电极位于所述壳体内，使得流体通道在捕获电极和对电极之间延伸。
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公开(公告)号：US20120145557A1
公开(公告)日：2012-06-14
申请号：US13377881
申请日：2010-07-12
申请人： Marko Baller , Victor Samper , Christian Rensch , Christoph Boeld
发明人： Marko Baller , Victor Samper , Christian Rensch , Christoph Boeld
CPC分类号： G21G1/001 , G21G2001/0015
摘要： Devices and methods for electrochemical phase transfer utilize at least one electrode formed from either glassy carbon or a carbon and polymer composite. The device includes a device housing defining an inlet port (42), an outlet port (44) and an elongate fluid passageway (36) extending therebetween. A capture electrode (12) and a counter electrode are positioned within said housing such that the fluid passageway extends between the capture and counter electrodes.
摘要翻译： 用于电化学相转移的装置和方法利用由玻璃碳或碳和聚合物复合材料形成的至少一个电极。 该装置包括限定入口端口（42），出口端口（44）和在其间延伸的细长流体通道（36）的装置壳体。 捕获电极（12）和对电极位于所述壳体内，使得流体通道在捕获电极和对电极之间延伸。
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公开(公告)号：US07652586B2
公开(公告)日：2010-01-26
申请号：US11504739
申请日：2006-08-15
申请人： Marko Baller , Marcin Alexy , Glenn S. Claydon , Peter Joseph Codella , Stacey Kennerly , Kuna Kishore , Anis Zribi , Guiju Song , Shivappa Goravar , Ajit Achuthan
发明人： Marko Baller , Marcin Alexy , Glenn S. Claydon , Peter Joseph Codella , Stacey Kennerly , Kuna Kishore , Anis Zribi , Guiju Song , Shivappa Goravar , Ajit Achuthan
CPC分类号： G01N27/22 , G01N17/008
摘要： According to one embodiment, a first capacitive element may be provided and associated with a surface where a fouling layer is to be detected. A second capacitive element may also be provided, and a capacitance between the first and second capacitive elements may be used to detect formation of the fouling layer. According to another embodiment, a thermal device is provided proximate to a surface where a fouling layer is to be detected. A detector (e.g., a thermometer or vibration detector) may detect a condition associated with the surface, and formation of the fouling layer may be determined based at least in part on the condition.
摘要翻译： 根据一个实施例，可以提供第一电容元件并与待检测污垢层的表面相关联。 还可以提供第二电容元件，并且可以使用第一和第二电容元件之间的电容来检测污垢层的形成。 根据另一个实施例，热敏装置设置在要被检测污垢层的表面附近。 检测器（例如，温度计或振动检测器）可以检测与表面相关联的状况，并且可以至少部分地基于条件来确定结垢层的形成。
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公开(公告)号：US20080041139A1
公开(公告)日：2008-02-21
申请号：US11504739
申请日：2006-08-15
申请人： Marko Baller , Marcin Alexy , Glenn S. Claydon , Peter Joseph Codella , Stacey Kennerly , Kuna Kishore , Anis Zribi , Guiju Song , Shivappa Goravar , Ajit Achuthan
发明人： Marko Baller , Marcin Alexy , Glenn S. Claydon , Peter Joseph Codella , Stacey Kennerly , Kuna Kishore , Anis Zribi , Guiju Song , Shivappa Goravar , Ajit Achuthan
CPC分类号： G01N27/22 , G01N17/008
摘要： According to one embodiment, a first capacitive element may be provided and associated with a surface where a fouling layer is to be detected. A second capacitive element may also be provided, and a capacitance between the first and second capacitive elements may be used to detect formation of the fouling layer. According to another embodiment, a thermal device is provided proximate to a surface where a fouling layer is to be detected. A detector (e.g., a thermometer or vibration detector) may detect a condition associated with the surface, and formation of the fouling layer may be determined based at least in part on the condition.
摘要翻译： 根据一个实施例，可以提供第一电容元件并与待检测污垢层的表面相关联。 还可以提供第二电容元件，并且可以使用第一和第二电容元件之间的电容来检测污垢层的形成。 根据另一个实施例，热敏装置设置在要被检测污垢层的表面附近。 检测器（例如，温度计或振动检测器）可以检测与表面相关联的状况，并且可以至少部分地基于条件来确定结垢层的形成。
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9.发明授权Method and apparatus for continuous sectional magnetic encoding to measure torque on large shafts 有权用于连续分段磁编码以测量大轴上扭矩的方法和装置公开(公告)号：US08468898B2
公开(公告)日：2013-06-25
申请号：US12914344
申请日：2010-10-28
申请人： Marko Baller , Christof Sihler
发明人： Marko Baller , Christof Sihler
IPC分类号： G01L3/02
摘要： Magnetically encoded shafts for use in detecting forces exerted on the shaft during operation. Magnetically encoded regions, arranged in tracks or bands, encircle the shaft and are formed within or affixed to the shaft. The magnetically encoded regions define force-sensitive regions therebetween. Magnetic fields surround the force-sensitive regions and are altered by force vectors passing through the force sensitive region. These magnetic fields are sensed by magnetic field sensors to determine various shaft parameters including, for example: shaft rotational speed, shaft rotational position, and forces exerted on the shaft, e.g., torque, bending forces, stress forces and strain forces. To provide continuous detection of shaft operational parameters and forces, dead zones between magnetically encoded regions are aligned with force sensitive regions associated with magnetically encoded regions in other bands.
摘要翻译： 用于在操作期间检测施加在轴上的力的磁编码轴。 布置在轨道或带中的磁编码区域环绕轴并形成在轴内或固定在轴上。 磁编码区域限定其间的力敏感区域。 磁场围绕力敏感区域，并且通过穿过力敏感区域的力矢量而改变。 这些磁场由磁场传感器感测，以确定各种轴参数，包括例如：轴转速，轴旋转位置和施加在轴上的力，例如扭矩，弯曲力，应力和应变力。 为了提供轴操作参数和力的连续检测，磁编码区域之间的死区与与其他带中的磁编码区域相关联的力敏感区域对准。
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公开(公告)号：US20120267561A1
公开(公告)日：2012-10-25
申请号：US13514132
申请日：2010-12-30
申请人： Victor Samper , Christian Rensch , Christoph Boeld , Marko Baller
发明人： Victor Samper , Christian Rensch , Christoph Boeld , Marko Baller
IPC分类号： F16K1/42
CPC分类号： F16K99/0001 , F16K99/0015 , F16K2099/008
摘要： A microvalve assembly (10) includes an elongate valve body (14) having opposed first and second major surfaces, the first major surface defining a valve recess (34) and the second major surface defining first and second fluid ports (20,22). Both the fluid input port and the fluid output port extend in fluid communication with the valve recess. A gasket (12) is freely positioned within the valve recess so as to extend in overlying registry with either or both of fluid ports. A valve cover (16) is bonded to the valve body and includes a first planar surface positioned in overlying registry with the valve recess so as to enclose the gasket therein. The valve cover is deflectable into the valve recess so as to cause the gasket to seal at least one of the fluid ports.
摘要翻译： 微阀组件（10）包括具有相对的第一和第二主表面的细长阀体（14），所述第一主表面限定阀凹部（34），所述第二主表面限定第一和第二流体端口（20,22）。 流体输入端口和流体输出端口都与阀门凹口流体连通地延伸。 垫片（12）自由地定位在阀凹部内，以便在任一个或两个流体端口的上面对准中延伸。 阀盖（16）与阀体结合并且包括位于与阀凹部对齐的第一平坦表面，以便将垫圈包围在其中。 阀盖可偏转到阀门凹口中，以便使垫圈密封至少一个流体端口。
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