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1.发明授权Polynucleotides encoding the novel human phosphatase, RET31, and variants thereof 有权编码新型人磷酸酶RET31的多核苷酸及其变体公开(公告)号：US07153678B2
公开(公告)日：2006-12-26
申请号：US10029345
申请日：2001-12-20
申请人： Donald G. Jackson , Chandra S. Ramanathan , John N. Feder , Liana Lee , Thomas C. Nelson , Nathan Siemers , Suzanne J. Suchard , Joshua Finger , C. Gordon Todderud , Dana Banas
发明人： Donald G. Jackson , Chandra S. Ramanathan , John N. Feder , Liana Lee , Thomas C. Nelson , Nathan Siemers , Suzanne J. Suchard , Joshua Finger , C. Gordon Todderud , Dana Banas
CPC分类号： G06F19/16 , A61K38/00 , C07K2319/00 , C07K2319/30 , C12N9/16 , C12Q1/6883 , C12Q2600/158 , C12Y301/03048 , G01N33/573 , G01N33/6893 , G01N2333/916 , G01N2500/00 , G01N2500/04 , Y02A90/26
摘要： The present invention provides novel polynucleotides encoding human phosphatase polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel human phosphatase polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly cardiovascular diseases and/or disorders. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
摘要翻译： 本发明提供编码人磷酸酶多肽，其片段和同源物的新型多核苷酸。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型人磷酸酶多肽应用于诊断，治疗和/或预防与这些多肽，特别是心血管疾病和/或病症相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。
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公开(公告)号：US20060014180A1
公开(公告)日：2006-01-19
申请号：US11143984
申请日：2005-06-02
申请人： Donald Jackson , Chandra Ramanathan , John Feder , Gabe Mintier , Liana Lee , Thomas Nelson , Nathan Siemers , David Bol , Suzanne Suchard , Gary Schieven , Joshua Finger , C. Todderrud , Donna Bassolino , Stanley Krystek , Dana Banas , Patrick McAtee
发明人： Donald Jackson , Chandra Ramanathan , John Feder , Gabe Mintier , Liana Lee , Thomas Nelson , Nathan Siemers , David Bol , Suzanne Suchard , Gary Schieven , Joshua Finger , C. Todderrud , Donna Bassolino , Stanley Krystek , Dana Banas , Patrick McAtee
CPC分类号： G06F19/16 , A61K38/00 , C07K2319/00 , C07K2319/30 , C12N9/16 , C12Q1/6883 , C12Q2600/158 , C12Y301/03048 , G01N33/573 , G01N33/6893 , G01N2333/916 , G01N2500/00 , G01N2500/04 , Y02A90/26
摘要： The present invention provides novel polynucleotides encoding human phosphatase polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel human phosphatase polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly cardiovascular diseases and/or disorders. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
摘要翻译： 本发明提供编码人磷酸酶多肽，其片段和同源物的新型多核苷酸。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型人磷酸酶多肽应用于诊断，治疗和/或预防与这些多肽，特别是心血管疾病和/或病症相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。
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公开(公告)号：US20050130286A1
公开(公告)日：2005-06-16
申请号：US10029345
申请日：2001-12-20
申请人： Donald Jackson , Chandra Ramanathan , John Feder , Gabe Mintier , Liana Lee , Thomas Nelson , Nathan Siemers , David Bol , Suzanne Suchard , Gary Schieven , Joshua Finger , C. Todderrud , Donna Bassolino , Stanley Krystek , Dana Banas , Patrick McAtee
发明人： Donald Jackson , Chandra Ramanathan , John Feder , Gabe Mintier , Liana Lee , Thomas Nelson , Nathan Siemers , David Bol , Suzanne Suchard , Gary Schieven , Joshua Finger , C. Todderrud , Donna Bassolino , Stanley Krystek , Dana Banas , Patrick McAtee
IPC分类号： A61K38/00 , A61K38/43 , A61K48/00 , A61P1/16 , A61P11/00 , A61P13/12 , A61P15/00 , A61P25/00 , A61P29/00 , A61P35/00 , A61P43/00 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/16 , C12N15/09 , C12N15/55 , C12P21/00 , C12Q1/02 , C12Q1/68 , G01N33/573 , G01N33/68 , G06F19/16 , C07H21/04
CPC分类号： G06F19/16 , A61K38/00 , C07K2319/00 , C07K2319/30 , C12N9/16 , C12Q1/6883 , C12Q2600/158 , C12Y301/03048 , G01N33/573 , G01N33/6893 , G01N2333/916 , G01N2500/00 , G01N2500/04 , Y02A90/26
摘要： The present invention provides novel polynucleotides encoding human phosphatase polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel human phosphatase polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly cardiovascular diseases and/or disorders. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
摘要翻译： 本发明提供编码人磷酸酶多肽，其片段和同源物的新型多核苷酸。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型人磷酸酶多肽应用于诊断，治疗和/或预防与这些多肽，特别是心血管疾病和/或病症相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。
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公开(公告)号：US07358074B2
公开(公告)日：2008-04-15
申请号：US11143984
申请日：2005-06-02
申请人： Donald G. Jackson , Chandra S. Ramanathan , Liana Lee , Nathan Siemers , Suzanne J. Suchard , Joshua Finger , C. Gordon Todderud , Dana Banas
发明人： Donald G. Jackson , Chandra S. Ramanathan , Liana Lee , Nathan Siemers , Suzanne J. Suchard , Joshua Finger , C. Gordon Todderud , Dana Banas
CPC分类号： G06F19/16 , A61K38/00 , C07K2319/00 , C07K2319/30 , C12N9/16 , C12Q1/6883 , C12Q2600/158 , C12Y301/03048 , G01N33/573 , G01N33/6893 , G01N2333/916 , G01N2500/00 , G01N2500/04 , Y02A90/26
摘要： The present invention provides novel polynucleotides encoding human phosphatase polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel human phosphatase polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly cardiovascular diseases and/or disorders. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
摘要翻译： 本发明提供编码人磷酸酶多肽，其片段和同源物的新型多核苷酸。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型人磷酸酶多肽应用于诊断，治疗和/或预防与这些多肽，特别是心血管疾病和/或病症相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。
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