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1.发明授权公开(公告)号：US06762841B1
公开(公告)日：2004-07-13
申请号：US09507850
申请日：2000-02-22
申请人： Susan L. Bragg , Danny D. Meyer
发明人： Susan L. Bragg , Danny D. Meyer
IPC分类号： G01N2100
CPC分类号： G01N21/8507 , G01N13/00 , G01N21/7703 , G01N33/15 , G01N2013/006
摘要： A method for performing spectral analysis in a pharmaceutical dissolution process. The method comprises inserting a fiber optic probe of a spectral analyzer into a dissolution vessel. The dissolution vessel contains a dissolution medium. The probe has a launch cable, a return cable, a launch lens portion, a return lens portion and a reflector. The reflector is spaced from both the lens portions. The cables, lens portions and reflector are arranged and adapted to form a light pathway whereby light transmitted through the launch cable passes through the launch lens portion, through a volume of the dissolution medium in the spacing between the launch lens portions and the reflector, and then through the return cable. The spacing between the reflector and the lens portions comprise a sample region. The fiber optic probe is sized and adapted to prevent bubbles in the dissolution medium from being trapped in the sample region. The method further comprises transmitting light along the optic pathway, and analyzing the transmitted light for determining certain optical properties of the dissolution medium in the optic pathway.
摘要翻译： 一种用于在药物溶出过程中进行光谱分析的方法。 该方法包括将光谱分析仪的光纤探针插入溶解容器中。 溶解容器含有溶解介质。 探头具有发射电缆，返回电缆，发射透镜部分，返回透镜部分和反射器。 反射器与透镜部分间隔开。 电缆，透镜部分和反射器被布置和适配成形成光通路，由此通过发射电缆的光线穿过发射透镜部分，通过在发射透镜部分和反射器之间的间隔中的溶解介质的体积，以及 然后通过返回电缆。 反射器和透镜部分之间的间隔包括样品区域。 光纤探头的尺寸和尺寸适于防止溶解介质中的气泡被捕获在样品区域中。 该方法还包括沿着光学路径传输光，并且分析透射光以确定光学路径中的溶解介质的某些光学特性。
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公开(公告)号：US5394427A
公开(公告)日：1995-02-28
申请号：US235689
申请日：1994-04-29
申请人： Ted S. McMinn , Dana A. Marshall , Danny D. Meyer
发明人： Ted S. McMinn , Dana A. Marshall , Danny D. Meyer
CPC分类号： H01S3/025 , H01S3/0407 , H01S3/042 , H01S3/0606
摘要： A housing for a slab laser gain media with a rectangular cross section which provides for a uniform flow of coolant over the slab top and bottom surfaces (18) and (20), while insulating the slab side surfaces (14) and (16). The slab gain media is bonded between two tabs at each end of the housing (48a, 48b, 50a, 50b). The slab top and bottom surfaces are made level with the tab top and bottom surfaces. Seals are placed on the continuous surface formed by the slab top and bottom surfaces and the tab top and bottom surfaces, thus sealing the ends of the housing, and also surrounding the coolant inlets and outlets. Windows (32) and (34) are then placed on top of each seal to form two thin cavities confining the coolant to flow across the slab top and bottom surfaces (18) and (20), and allowing for the close-coupling of either one or two pump sources, such as a two dimensional laser diode array assembly (58) and (60).
摘要翻译： 用于板坯激光器的壳体获得具有矩形横截面的介质，其在板坯顶部和底部表面（18）和（20）之间提供均匀的冷却剂流，同时绝缘板坯侧表面（14）和（16）。 板坯增益介质结合在壳体（48a，48b，50a，50b）的每个端部处的两个突片之间。 平板顶部和底部表面与凸起顶部和底部表面平齐。 密封件放置在由板坯顶部和底部表面以及突出部顶部和底部表面形成的连续表面上，从而密封壳体的端部，并且还围绕冷却剂入口和出口。 然后将窗口（32）和（34）放置在每个密封件的顶部上以形成限制冷却剂流过板坯顶部和底部表面（18）和（20）的两个薄的空腔，并且允许两者之间的紧耦合 一个或两个泵浦源，例如二维激光二极管阵列组件（58）和（60）。
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公开(公告)号：US4393393A
公开(公告)日：1983-07-12
申请号：US261832
申请日：1981-05-08
CPC分类号： H01S5/02423 , H01L2924/0002 , H01S5/02272 , H01S5/4018 , H01S5/4025
摘要： A laser diode is soldered between metal plates for intimate thermal and electrical contact. The plates are prefabricated and are provided with an insulative spacer therebetween. The two metal plates are held together in a preferred orientation by the spacer which is firmly adhered and sealed to the two plates during the diode soldering operation. The metal plates are constructed from material thin enough that they yield under thermal pressure of the diode to eliminate mechanical strain on the diode during thermal cycling. Backup plates are provided in contact with the diode mounting plates to feed electrical energy thereto.
摘要翻译： 激光二极管焊接在金属板之间，以实现热和电接触。 板是预制的并且在它们之间设置有绝缘间隔件。 两个金属板通过在二极管焊接操作期间牢固地粘附并密封到两个板的间隔件以优选的取向保持在一起。 金属板由足够薄的材料构成，使得它们在二极管的热压下产生，以消除热循环期间二极管的机械应变。 提供与二极管安装板接触的备用板以向其供电电能。
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公开(公告)号：USD285290S
公开(公告)日：1986-08-26
申请号：US492802
申请日：1983-05-09
申请人： Yehuda Shalon , Tadmor Shalon , Danny D. Meyer
设计人： Yehuda Shalon , Tadmor Shalon , Danny D. Meyer
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公开(公告)号：US4508532A
公开(公告)日：1985-04-02
申请号：US530730
申请日：1983-09-09
CPC分类号： A61F9/00736
摘要： An ophthalmic aspirator and cystotome having a hand-held, motorized instrument which is operated by a battery-run control system. The instrument includes a disposable coaxial aspirator-irrigator tip and a wormdrive mechanism for bidirectional, variable speed operation and also includes a disposable scalpel tip with infusion/irrigation orifice for communication with an intraveneous solution bag. The scalpel tip is coupled through a clutch mechanism to the motor, which may be adjusted by the control system to make single or repeated cuts in either of two rotary directions. The aspirator's most frequently needed controls are mounted on the handpiece to provide an easily operable instrument of great precision for use in eye surgery. The instrument features an electronic control circuit housed in part within a desk top or suspendable unit and in part within the handpiece. The circuit may be switched between the aspirator mode and the cystotome mode and provides control signals to a motor carried within the handpiece. In the aspirator mode the circuit generates aspirate and backflush signals at the touch of a control switch mounted on the handpiece. Flow rates are continuously variable by means of a potentiometer control in the butt of the handpiece. In the cystotome mode the control switch commands either single cutting strokes or repeated cutting strokes in either of two rotary directions, the direction being selected by the potentiometer control.
摘要翻译： 具有由电池运行控制系统操作的手持式电动仪器的眼科抽吸器和囊肿切片机。 该仪器包括一次性同轴抽吸器 - 冲洗器尖端和用于双向，可变速度操作的蜗杆传动机构，并且还包括具有输注/冲洗孔的一次性手术刀尖，用于与静脉内溶液袋通信。 手术刀尖通过离合器机构联接到电动机，其可以由控制系统调节以在两个旋转方向中的任一个中进行单次或重复切割。 吸气器最常用的控制器安装在手持件上，以提供用于眼科手术的高精度的易于操作的仪器。 该仪器具有电子控制电路，其部分地容纳在桌面或可悬挂单元内，并且部分地容纳在手持件内。 电路可以在吸气器模式和膀胱切开模式之间切换，并且向手持件中携带的电动机提供控制信号。 在吸气器模式下，电路在安装在手机上的控制开关触摸时产生抽吸和反冲信号。 通过手柄对接处的电位器控制，流速可以连续变化。 在膀胱切开模式下，控制开关可以在两个旋转方向中的任意一个方向上进行单次切削冲程或重复切削冲程，该方向由电位计控制选择。
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公开(公告)号：US4719011A
公开(公告)日：1988-01-12
申请号：US5641
申请日：1987-01-21
申请人： Yehuda Shalon , Danny D. Meyer
发明人： Yehuda Shalon , Danny D. Meyer
CPC分类号： B01D15/22 , B01D15/14 , G01N30/6017 , G01N30/603 , G01N30/6039 , G01N30/6069 , G01N30/6026
摘要： This invention relates to high pressure liquid chromatography and to chromatographic columns employed therein. These columns may be modularly modified as to length and/or internal diameter and may contain other components in the modular system, for example, column sections, adapters and cone adapters, for joining column sections of different internal diameters, and end plate units for funnelling in or discharging out fluids; said end caps or lids, with or without funnel shaped means, for facilitating the liquid entrance or exit; and porous frits, with or without handles, all used in conjunction with the column sections to facilitate their usage for performance of specific chromatographic functions. The column sections have terminal flange-like means for accommodating the joining together for formations of a system suitable for high pressure liquid chromatography of the preparative or semi-preparative type.
摘要翻译： 本发明涉及高压液相色谱和其中使用的色谱柱。 这些柱可以对长度和/或内径进行模块化修改，并且可以包含模块化系统中的其他部件，例如用于连接不同内径的柱部分的柱部分，适配器和锥形适配器，以及用于漏斗的端板单元 流入或排出液体; 所述端盖或盖具有或不具有漏斗形装置，用于促进液体的入口或出口; 和带有或不带手柄的多孔玻璃料，都与柱部分一起使用，以方便它们用于执行特定色谱功能。 柱部分具有端子法兰状装置，用于容纳连接在一起用于制备或半制备型高压液相色谱的系统的结构。
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公开(公告)号：US4315225A
公开(公告)日：1982-02-09
申请号：US69311
申请日：1979-08-24
CPC分类号： H01S5/02272 , H01S5/02423 , H01S5/02264 , H01S5/4018 , H01S5/4025 , Y10S257/926
摘要： A laser diode is soldered between metal plates for intimate thermal and electrical contact. The plates are prefabricated and are provided with an insulated spacer therebetween. The two metal plates are held together in a preferred orientation by the spacer which is firmly adhered and sealed to the two plates during the diode soldering operation. The laser diodes so mounted can be tested in this configuration and after testing are formed into an array by stacking the laser diode subassemblies providing spacer elements therebetween and series contacts from one end to the other of the array so that an array of laser diodes with matched characteristics can be constructed in a line which may not be in alignment with the total package to provide an intense light output at a predetermined wavelength.
摘要翻译： 激光二极管焊接在金属板之间，以实现热和电接触。 这些板是预制的，并且在它们之间设置有绝缘垫片。 两个金属板通过在二极管焊接操作期间牢固地粘附并密封到两个板的间隔件以优选的取向保持在一起。 可以在该配置中测试如此安装的激光二极管，并且通过堆叠在其间提供间隔元件的激光二极管子组件和从阵列的一端到另一阵列的串联触点而将测试形成为阵列之后，使得具有匹配的激光二极管阵列 特性可以构成一条线，该线可能不与整个封装对齐，以提供预定波长的强光输出。
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