Dual stent
    3.
    发明授权
    Dual stent 失效
    双支架

    公开(公告)号:US5899934A

    公开(公告)日:1999-05-04

    申请号:US791209

    申请日:1997-01-31

    IPC分类号: A61F2/90 A61F2/06

    摘要: A medical device for use in supporting a luminal surface of a human or animal body comprising a catheter, a stent mounted on the distal end of the catheter, the stent comprising a hollow cylindrical first wire segment and a hollow cylindrical second wire segment, and a means on the catheter for releasing the stent in the expanded diameter from the catheter. The first wire segment forms a plurality of spaced-apart first wire segment elements each extending 360 degrees around the hollow cylinder, each of the first wire segment elements having a plurality of extendible portions which permit the first wire segment elements to be expanded from the unexpanded diameter to a second, expanded diameter, the first wire segment proximal end having a straight tail extending proximally and longitudinally therefrom. The second wire segment forming a plurality of spaced-apart second wire segment elements each extending 360 degrees around the hollow cylinder, each of the second wire segment elements having a plurality of extendible portions which permit the second wire segment elements to be expanded from the unexpanded diameter to a second, expanded diameter, the second wire segment distal end having a straight tail extending distally and longitudinally therefrom.

    摘要翻译: 一种用于支撑人或动物体的腔表面的医疗装置,包括导管,安装在导管远端的支架,支架包括中空圆柱形第一线段和中空圆柱形第二线段,以及 用于从导管释放扩张直径的支架的导管上的装置。 第一线段形成多个间隔开的第一线段元件,每个第一线段元件围绕中空圆柱体360度延伸360度,每个第一线段元件具有多个可延伸部分,其允许第一线段元件从未膨胀 直径到第二扩展直径,第一线段近端具有从其向近侧和纵向延伸的直尾。 第二线段形成多个间隔开的第二线段元件,每个第二线段元件围绕中空圆柱体360度延伸360度,每个第二线段元件具有多个可延伸部分,其允许第二线段元件从未膨胀 直径延伸到第二扩张直径,第二线段远端具有从其向远侧和纵向延伸的直尾。

    Injectable polymeric bodies
    5.
    发明授权
    Injectable polymeric bodies 失效
    可注射的聚合体

    公开(公告)号:US5158573A

    公开(公告)日:1992-10-27

    申请号:US675346

    申请日:1991-03-22

    申请人: Eric P. Berg

    发明人: Eric P. Berg

    摘要: An injectable composition consisting of a plurality of discrete physiologically-compatible, non-biodegradable, silicone rubber bodies, said bodies having (i) a maximum outside dimension of from about 0.005 to 0.08 inch (125 to 2000.mu.), (ii) reversible deformability of about 20 to 75% of their unstressed outside dimension and (iii) a lubricious surface, wherein the lubricious surface is provided by a thin film coating of a liquid lubricant; and a method for treating a tissue condition in a patient using said composition.

    摘要翻译: 由多个离散的生理上相容的,不可生物降解的硅橡胶体组成的可注射组合物,所述主体具有(i)最大外部尺寸为约0.005至0.08英寸(125至2000μm),(ii)可逆变形性 约20至75%的未受压外部尺寸和(iii)润滑表面,其中润滑表面由液体润滑剂的薄膜涂层提供; 以及使用所述组合物治疗患者的组织状况的方法。

    Preparation of injectable polymeric bodies
    6.
    发明授权
    Preparation of injectable polymeric bodies 失效
    可注射聚合物体的制备

    公开(公告)号:US5116387A

    公开(公告)日:1992-05-26

    申请号:US639616

    申请日:1991-01-10

    申请人: Eric P. Berg

    发明人: Eric P. Berg

    摘要: An injectable composition comprising a plurality of discrete physiologically-compataible, non-biodegradable, polymeric bodies, said bodies having (i) an average outside diameter of from about 0.005 to 0.20 inch, (ii) reversible deformability of about 20 to 75% of their unstressed outside diameter, and (iii) a lubricious surface; a process for the preparation of said composition and a method for treating a tissue condition in a patient using said composition.

    摘要翻译: 一种可注射组合物,其包含多个离散的生理上可分解的,不可生物降解的聚合物体,所述体具有(i)约0.005至0.20英寸的平均外径,(ii)约20至75%的可逆变形性 外径不大,(iii)润滑表面; 用于制备所述组合物的方法和使用所述组合物治疗患者的组织状况的方法。

    Method and apparatus for valving body fluids
    7.
    发明授权
    Method and apparatus for valving body fluids 失效
    用于阀体阀体的方法和装置

    公开(公告)号:US5112306A

    公开(公告)日:1992-05-12

    申请号:US457423

    申请日:1989-12-27

    IPC分类号: A61F2/00 A61F2/958 A61M25/00

    摘要: A method and apparatus for valving body fluids involving a flexible tubular body with a drainage canal therethrough, including collapsible means for blocking the passageway and thereby preventing the flow of urine. The length of the device is such that one end protrudes into the bladder and the other end terminates interior of the meatus. The device includes a means for anchoring to secure it in place and a plug device for deflating and releasing the anchoring means and for collapsing the blocking means to facilitate removal of the device from the body. The device is manually actuable to an open position and means are provided to delay the closing of the device for a sufficient period of time to allow voiding of the bladder. The collapsible and expandable nature of the device facilitates its insertion and removal, particularly while passing through areas of restricted diameter.

    摘要翻译: 一种用于对包括具有穿过其中的排水管的柔性管状体的体液进行阀体的方法和装置,包括用于阻塞通道并因此防止尿液流动的可折叠装置。 装置的长度使得一端突出到膀胱中,另一端终止于肠道的内部。 该装置包括用于锚固以将其固定在适当位置的装置和用于放气和释放锚固装置并用于塌缩阻挡装置以便于将装置从身体移除的塞装置。 该装置可手动地致动到打开位置,并且提供装置以延迟装置的关闭足够的时间以允许气囊的排尿。 该装置的可折叠和可膨胀性质有助于其插入和移除,特别是在通过有限直径的区域时。

    Method for valving body fluids
    8.
    发明授权
    Method for valving body fluids 失效
    阀体液体的方法

    公开(公告)号:US4909785A

    公开(公告)日:1990-03-20

    申请号:US267748

    申请日:1988-11-02

    IPC分类号: A61F2/00 A61F2/958 A61M25/00

    摘要: A method and apparatus for valving body fluids involving a flexible tubular body with a drainage canal therethrough, including collapsible means for blocking the passageway and thereby preventing the flow of urine. The length of the device is such that one end protrudes into the bladder and the other end terminates interior of the meatus. The device includes a means for anchoring to secure it in place and a plug device for deflating and releasing the anchoring means and for collapsing the blocking means to facilitate removal of the device from the body. The device is manually actuable to an open position and means are provided to delay the closing of the device for a sufficient period of time to allow voiding of the bladder. The collapsible and expandable nature of the device facilitates its insertion and removal, particularly while passing through areas of restricted diameter.

    摘要翻译: 一种用于对包括具有穿过其中的排水管的柔性管状体的体液进行阀体的方法和装置,包括用于阻塞通道并因此防止尿液流动的可折叠装置。 装置的长度使得一端突出到膀胱中,另一端终止于肠道的内部。 该装置包括用于锚固以将其固定在适当位置的装置和用于放气和释放锚固装置并用于塌缩阻挡装置以便于将装置从身体移除的塞装置。 该装置可手动地致动到打开位置,并且提供装置以延迟装置的关闭足够的时间以允许气囊的排尿。 该装置的可折叠和可膨胀性质有助于其插入和移除,特别是在通过有限直径的区域时。

    Mucoadhesive drug delivery devices and methods of making and using thereof
    10.
    发明授权
    Mucoadhesive drug delivery devices and methods of making and using thereof 有权
    粘膜粘附药物递送装置及其制造和使用方法

    公开(公告)号:US08529939B2

    公开(公告)日:2013-09-10

    申请号:US11007053

    申请日:2004-12-08

    摘要: The present invention relates to mucoadhesive drug delivery devices and their methods of preparation and use. More specifically the present invention relates to mucoadhesive drug delivery devices comprising one or more biocompatible purified proteins combined with one or more biocompatible solvents and one or more mucoadhesive agents. The mucoadhesive drug delivery devices may also include one or more pharmacologically active agents. The drug delivery devices of the present invention adhere to mucosal tissue, thereby providing a vehicle for delivery of the pharmacologically active agent(s) through such tissue.

    摘要翻译: 本发明涉及粘膜粘附药物递送装置及其制备和使用方法。 更具体地,本发明涉及粘膜粘附药物递送装置,其包含与一种或多种生物相容性溶剂和一种或多种粘膜粘附剂组合的一种或多种生物相容性纯化蛋白质。 粘膜粘附药物递送装置还可以包括一种或多种药理活性剂。 本发明的药物输送装置粘附于粘膜组织,从而提供用于通过这种组织输送药理活性剂的载体。