公开(公告)号：US20220193256A1

公开(公告)日：2022-06-23

申请号：US17604590

申请日：2020-04-17

申请人： FUNDACIÓN CIDETEC

发明人： Raquel GRACIA ESPAÑA ,  Julie MOVELLAN ,  Marco MARRADI ,  Damien DUPIN ,  lraida LOINAZ BORDONABE ,  Xabier MURGIA ESTEVE

IPC分类号： A61K47/69 ,  A61K47/61

摘要： The present invention relates to a water-dispersible single-chain dextran methacrylate or acrylate based nanoconjugate, which comprises a water-dispersible single-chain dextran methacrylate or acrylate based nanoparticle and one or more hydrophilic active ingredients, and having: a particle size from 3 nm to 50 nm, a zeta potential from −25 mV to +20 mV, a percentage of intra-molecular crosslinking from 3% to 45% molar % of the total amount of monomer units present in the dextran methacrylate or acrylate chain, and a drug loading from 20% to 40% by weight of the drug in relation to the total weight of the nanoconjugate. It also relates to processes for their preparation, compositions containing them and their use in therapy.

公开(公告)号：US10550205B2

公开(公告)日：2020-02-04

申请号：US15520809

申请日：2015-11-02

申请人： FUNDACIÓN CIDETEC

发明人： Miren Karmele Aiertza Otxotorena ,  Laura Sánchez Abella ,  Ana Belén Benito Collado ,  Iraida Loinaz Bordonabe ,  Germán Cabañero ,  Hans-Jürgen Grande ,  Marco Marradi ,  Raquel Gracia España

IPC分类号： C08F8/32 ,  A61K49/00 ,  A61K49/18 ,  A61K47/69 ,  C08G75/12

摘要： The present invention comprises a process for preparing water-dispersible single-chain polymeric nanoparticles, which comprises cross-linking a polymer having a solubility equal to or higher than 100 mg per litre of water, and an amount of complementary reactive groups comprised from 5 to 60 molar % of the total amount of monomer units present in the polymer chain; with a crosslinking agent having crosslinkable groups; at a temperature comprised from 20 to 25° C. in the absence of a catalyst; to obtain water-dispersible conjugates and compositions containing the nanoparticle; and the use thereof.

公开(公告)号：US20240021922A1

公开(公告)日：2024-01-18

申请号：US18031825

申请日：2021-09-15

申请人： FUNDACIÓN CIDETEC

发明人： Jose Alberto BLÁZQUEZ MARTIN ,  Aroa RAMOS MAINAR ,  Idoia URDAMPILLETA GONZALEZ

IPC分类号： H01M12/06 ,  H01M4/42 ,  H01M4/86 ,  H01M50/46

CPC分类号： H01M12/065 ,  H01M4/42 ,  H01M4/8615 ,  H01M50/46 ,  H01M2004/027

摘要： It is provided a secondary zinc-air battery comprising at least two secondary zinc-air electrochemical cells, each cell comprising an air cathode that is a bifunctional air electrode (BAE); a zinc-containing anode; a free electrolyte contained in a reservoir; and a first and a second separators; wherein the zinc-containing anode is disposed between the BAE and the free electrolyte, and is separated from the BAE by the first separator and separated from the free electrolyte by the second separator, and wherein the at least two cells are assembled together in such a way that a unique electrolyte reservoir containing the free electrolyte is placed between at least two zinc anodes and thus is shared by the at least two secondary zinc-air electrochemical cells.

公开(公告)号：US11306219B2

公开(公告)日：2022-04-19

申请号：US16466617

申请日：2017-12-21

申请人： FUNDACIÓN CIDETEC

发明人： Eneko Azaceta Muñoz ,  Jesús Palenzuela Conde ,  Ramón Tena Zaera ,  Estibaliz Medina

IPC分类号： C09D139/04 ,  C09D5/00

摘要： It is provided a coating composition comprising an ionic liquid, and a crosslinked polymeric ionic liquid, wherein the crosslinked polymeric ionic liquid and the ionic liquid are not linked through covalent bonds, and wherein the crosslinked polymeric ionic liquid is linked to a substrate surface. It is also provided a process for its preparation, as well as an article of manufacture at least in part coated with the coating composition as defined above.

公开(公告)号：US20240291031A1

公开(公告)日：2024-08-29

申请号：US18570587

申请日：2022-06-03

申请人： VARTA Microbattery GmbH ,  Fundación CIDETEC

发明人： Idoia Urdampilleta González ,  Martin Krebs ,  Iñaki Gómez Agúndez ,  Luis Cesar Colmenares Rausseo ,  Jose Alberto Blázquez Martin

IPC分类号： H01M10/0565 ,  H01M4/02 ,  H01M4/04 ,  H01M4/42 ,  H01M4/48 ,  H01M4/62

CPC分类号： H01M10/0565 ,  H01M4/0414 ,  H01M4/42 ,  H01M4/483 ,  H01M4/622 ,  H01M2004/027 ,  H01M2004/028 ,  H01M2300/0082 ,  H01M2300/0085

摘要： An electrolyte hydrogel for an electrochemical cell includes a self standing polymer network with a crosslinked, non-ionic polymer and a cationic polymer and a salt in an aqueous solvent and/or dispersant.

公开(公告)号：US20210069118A1

公开(公告)日：2021-03-11

申请号：US16753740

申请日：2018-10-08

申请人： Université De Bordeaux ,  Institut Polytechnique De Bordeaux ,  Centre National De La Recherche Scientifique ,  Fundación Cidetec

发明人： Sébastien LECOMMANDOUX ,  Damien DUPIN ,  Iraida LOINAZ BORDONABE ,  Hans-Jürgen GRANDE TELLERIA ,  Aitziber LOPEZ ELORZA ,  Elisabeth GARANGER

IPC分类号： A61K9/50 ,  A61K9/51 ,  A61K9/107 ,  B01J13/08 ,  A61K36/9066 ,  C08G81/00 ,  A61K31/164 ,  A61K31/23 ,  A61K31/728 ,  A61K31/704

摘要： The present invention relates to the use of a copolymer having the following formula (II): wherein: A1 is a linker, preferably an enzyme cleavable peptide sequence, and y is 0 or 1; AA is a residue of a hydrophobic amino acid; x is an integer comprised between 17 and 270; n is an integer comprised between 5 and 170; and m is an integer comprised between 0 and 80; optionally in the presence of a co-surfactant, as surfactant for the stabilization of an emulsion at a pH between 4 and 6.5.

公开(公告)号：US20180223213A1

公开(公告)日：2018-08-09

申请号：US15562339

申请日：2016-03-31

申请人： FUNDACIÓN CIDETEC

发明人： Ignacio GARCÍA ALONSO ,  Sarah MONTES PÉREZ ,  Ibon ODRIOZOLA ,  Germán CABAÑERO ,  Hans-Jürgen GRANDE ,  Ramón TENA ZAERA

IPC分类号： C10M125/22 ,  C07C43/13 ,  C07C41/18 ,  C07C31/20 ,  C07C29/00 ,  C07C215/14 ,  C07C213/08 ,  C08G65/326 ,  C07C215/08 ,  C07C321/04 ,  C07C319/12 ,  C08K7/14 ,  C08K9/04 ,  C08K9/08 ,  C08K3/30 ,  C10M159/18 ,  C01G39/06

CPC分类号： C10M125/22 ,  C01B19/007 ,  C01G39/06 ,  C01G41/00 ,  C01P2002/82 ,  C01P2002/88 ,  C01P2004/03 ,  C01P2004/04 ,  C01P2004/10 ,  C01P2004/13 ,  C01P2004/16 ,  C01P2004/24 ,  C01P2004/32 ,  C01P2004/62 ,  C01P2004/64 ,  C07C29/00 ,  C07C31/20 ,  C07C31/205 ,  C07C41/18 ,  C07C43/132 ,  C07C213/08 ,  C07C215/08 ,  C07C215/14 ,  C07C319/12 ,  C07C321/04 ,  C08G65/326 ,  C08K3/30 ,  C08K7/14 ,  C08K9/04 ,  C08K9/08 ,  C08K2003/3009 ,  C08K2201/011 ,  C10M159/18 ,  C10M2201/065 ,  C10M2201/066 ,  C10M2227/066 ,  C10M2227/09 ,  C10N2210/06 ,  C10N2220/082 ,  C10N2230/06

摘要： The present invention provides a Molybdenum or Tungsten chalcogenide nanoobject having: (a) an object size comprised from 0.1 to 500 nm, and (b) from 1 to 99% by weight of molecules of formula (I) with respect to the total weight of the nanoobject, wherein: A is —OH; X is selected from: (C1-C20)alkyl optionally substituted with one or more radicals; a 2 to 20-member heteroalkyl optionally substituted with one or more radicals; and a homopolymer or copolymer comprising a polymeric chain; B is selected from: H, —OH, —NH2, (C1-C4)alkyl, halogen, phenyl substituted with one or more halogen radicals, benzyl substituted with one or more halogen radicals, —C(═O)R3, —C(═O)(R7), —OC(═O)(O)R3, —C(═O)(O−), —C(═O)(O)R3, —OR3, —CH(OR3)(OR4), —C(OR3)(OR4)(R5), —C(OR3)(OR4)(OR5), —C(OR3)(OR4)(OR5)(OR6), —NR1R2, —N+R1R2R3, —C(═NR1)(R2), —C(═O)(NR1R2), —N(C(═O)(R1)) (C(═O)(R2))(R3), —O(CN), —NC(═O), —ONO2, —CN, —NC, —ON(═O), —NO2, —NO, —C5H4N, —SR1, —SSR1, —S(═O)(R1), — S(═O)(═O)(R1), —S(═O)(OH), —S(═O)(═O)(OH), —SCN, —NCS, —C(═S)(R1), —PR1R2, —P(═O)(OH)2, —OP(═O)(OH)2, —OP(═O)(OR1)(OR2), —B(OH), —B(OR1)(OR2), and —B(OR1)(R2); provided that when B is —H or (C1-C4) alkyl, then X is a homopolymer, a copolymer, or a 2 to 20-member heteroalkyl optionally substituted with one or more radicals as defined above.The present invention also provides processes for the preparation of the nanoobjects, their use as additive for reducing the friction coefficient of a material, and compositions comprising thereof. A-X-B  (I)

公开(公告)号：US20170291982A1

公开(公告)日：2017-10-12

申请号：US15509151

申请日：2015-09-21

申请人： FUNDACIÓN CIDETEC

发明人： Ibon ODRIOZOLA ,  Alaitz RUIZ DE LUZURIAGA ,  Alaitz REKONDO ,  Roberto MARTÍN ,  Germán CABAÑERO ,  Hans-Jürgen GRANDE

IPC分类号： C08G18/32 ,  C08J11/12 ,  C08G18/65 ,  C08G18/75 ,  C08G18/48 ,  C08G18/10 ,  C08G18/24

CPC分类号： C08G18/3243 ,  C08G18/10 ,  C08G18/246 ,  C08G18/4825 ,  C08G18/4829 ,  C08G18/4845 ,  C08G18/6529 ,  C08G18/755 ,  C08G18/758 ,  C08J11/12 ,  C08J2375/12 ,  C09D175/02 ,  C09D175/04 ,  C09J175/02 ,  C09J175/04 ,  C08G18/7843

摘要： The polymer comprises units of formula (I) and of formula (Ibis), being comprised the molar ratio between units (I) and (Ibis) comprised from 1.0:0.2 to 1.0:0.8, and wherein R4 are independently selected from radicals of formula (II), (III), and (IV), R1 and R1′ are independently selected from: —H, (C1-C20)alkyl, (C5-C14)aryl, —OR5, —(CO)R6, —O(CO)R7, —(SO)R8, —NH—CO—R9, —COOR10, —NR11R12, —NO2, and halogen; R2, R2′, R3, and R3′ are —H; P is a polymeric chain, R5 to R12 are independently selected: —H, (C1-C20)alkyl, and (C5-C14)aryl;R13 and R14 are independently selected from (C1-C5)alkyl, and (C5-C14)aryl;, m is from 3 to 4; n is from 1 to 2; and p is from 1 to 2 provided that n+m+p sums 6; the polymer comprising from 5 to 25 weight % of urea moieties, and having H-bonding and pi-pi staking interactions between the urea groups, and a tensile strength comprised from 3 to 15 MPa.

公开(公告)号：US20240336784A1

公开(公告)日：2024-10-10

申请号：US18743009

申请日：2024-06-13

申请人： The University of the Basque Country/Institute ,  Fundación Cidetec

发明人： José Ramón LEIZA ,  Maria PAULIS ,  Stefano CHIMENTI ,  Jesus Manuel VEGA ,  Eva GARCIA

IPC分类号： C09D5/08 ,  C08F2/22 ,  C08F2/38 ,  C08F220/14 ,  C08F293/00 ,  C09D133/12

CPC分类号： C09D5/08 ,  C08F2/22 ,  C08F2/38 ,  C08F220/14 ,  C08F293/005 ,  C09D133/12

摘要： The present invention is directed to a method for producing a coating system providing corrosion-protective properties when applied to metal surfaces, particularly in the form of a water-based (waterborne) composition, preferably in the form of a dispersion (i.e. emulsion or latex, respectively), as well as to coating system thus produced and to its various applications. The resulting coating system provides superior properties with respect to corrosion protection, on the one hand, and adhesion to metal surfaces, on the other hand, while at the same time being environmentally compatible and easy to use and to apply and being producible in an economic way.

公开(公告)号：US20230387512A1

公开(公告)日：2023-11-30

申请号：US18031807

申请日：2021-09-15

申请人： FUNDACIÓN CIDETEC

发明人： Jose Alberto BLÁZQUEZ MARTIN ,  Aroa RAMOS MAINAR ,  Elena IRUIN AMATRIAIN ,  Idoia URDAMPILLETA GONZALEZ

IPC分类号： H01M12/08 ,  H01M12/02 ,  H01M4/24 ,  H01M4/38 ,  H01M4/48 ,  H01M4/62

CPC分类号： H01M12/085 ,  H01M12/02 ,  H01M4/244 ,  H01M4/38 ,  H01M4/48 ,  H01M4/622 ,  H01M2300/0014 ,  H01M2004/027

摘要： It is provided a secondary zinc-air electrochemical cell comprising an air cathode that is a bifunctional air electrode (BAE); a zinc-containing anode; a free electrolyte contained in a reservoir; and a first and a second separators; wherein the zinc-containing anode is disposed between the BAE and the free electrolyte, and is separated from the BAE by the first separator and separated from the free electrolyte by the second separator. It is also provided a process for the preparation of the secondary zinc-air cell, and a battery comprising at least one cell, and wherein no free electrolyte contained in a reservoir is disposed between the BAE and the zinc-containing anode.