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公开(公告)号：US20240264082A1
公开(公告)日：2024-08-08
申请号：US18640239
申请日：2024-04-19
Applicant: Go!Foton, Inc.
Inventor： Shuya OGI , Takashi Fukuzawa
CPC classification number: G01N21/6486 , C12Q1/686 , G01N2021/174
Abstract: A reaction processor includes: a reaction processing vessel; a first optical head including a first objective lens OB1 for irradiating a sample with first excitation light and collecting first fluorescence generated from the sample; a second optical head including a second objective lens for irradiating a sample with second excitation light and collecting second fluorescence generated from the sample; and a holding member holding the first optical head and the second optical head. The wavelength range of the first fluorescence and the wavelength range of the second excitation light at least partially overlap with each other. A distance between the optical axis of the first objective lens and the optical axis of the second objective lens satisfies 2·P0+2·P1+4·P2+4·P3
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公开(公告)号：US11541394B2
公开(公告)日：2023-01-03
申请号：US16687804
申请日：2019-11-19
Applicant: Nippon Sheet Glass Company, Limited , Go!Foton, Inc.
Inventor： Takashi Fukuzawa , Naofumi Nishizawa , Hisao Nagata
Abstract: A reaction processor is provided with a reaction processing vessel in which a channel is formed, a liquid feeding system, a temperature control system for providing a high temperature region and a low temperature region to the channel, and a fluorescence detector for detecting the sample passing through a fluorescence detection region of the channel, and a CPU for controlling the liquid feeding system based on a signal that is detected. A target stop position X[L]0(n+1) of the sample in the low temperature region in an (n+1)th cycle is corrected from a target stop position X[L]0(n) of the sample in the low temperature region in the nth cycle based on the result of stopping control on the sample in the nth cycle.
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公开(公告)号：US12222289B2
公开(公告)日：2025-02-11
申请号：US17124655
申请日：2020-12-17
Applicant: Go!Foton, Inc.
Inventor： Shuya Ogi , Takashi Fukuzawa
Abstract: A reaction processor includes: a reaction processing vessel; a first optical head including a first objective lens OB1 for irradiating a sample with first excitation light and collecting first fluorescence generated from the sample; a second optical head including a second objective lens for irradiating a sample with second excitation light and collecting second fluorescence generated from the sample; and a holding member holding the first optical head and the second optical head. The wavelength range of the first fluorescence and the wavelength range of the second excitation light at least partially overlap with each other. A distance between the optical axis of the first objective lens and the optical axis of the second objective lens satisfies 2·P0+2·P1+4·P2+4·P3
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公开(公告)号：US10988800B2
公开(公告)日：2021-04-27
申请号：US15993814
申请日：2018-05-31
Applicant: Nippon Sheet Glass Company, Limited , NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY , Go!Foton, Inc.
Inventor： Takashi Fukuzawa , Hidenori Nagai , Naofumi Nishizawa
IPC: C12P19/34 , C12Q1/6848 , G01N37/00 , C12M1/00 , G01N35/08 , B01L3/00 , B01L7/00 , C12Q1/686 , G01N21/64
Abstract: A PCR reaction vessel includes: a substrate; a channel formed on the substrate; a pair of filters, a first filter and a second filter, provided at respective ends of the channel; a pair of air communication ports, a first air communication port and a second air communication port, that communicate with the channel through the first filter and the second filter; a thermal cycle region formed between the first filter and the second filter in the channel; a branch point formed between the first filter and the second filter in the channel; a branched channel whose one end is connected to the branch point; and a sample introduction port formed at the other end of the branched channel.
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公开(公告)号：US12186756B2
公开(公告)日：2025-01-07
申请号：US17243770
申请日：2021-04-29
Applicant: Go!Foton, Inc.
Inventor： Takashi Fukuzawa
Abstract: A reaction processor includes: a vessel installation unit for installing a reaction processing vessel provided with a channel formed in a substrate; a high temperature heater and a medium temperature heater for adjusting the temperature of the channel of the reaction processing vessel; a vessel alignment mechanism for adjusting the position of the reaction processing vessel 10; and a housing that has a housing main unit and a cover portion capable of being opened and closed with respect to the housing main unit and that houses the vessel installation unit, the high temperature heater, the medium temperature heater, and the vessel alignment mechanism. In conjunction with the state of the cover portion being changed from an open state to a closed state, the vessel alignment mechanism aligns the reaction processing vessel such that the reaction processing vessel can be heated by the high temperature heater and the medium temperature heater.
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Patent Agency Ranking
公开(公告)号：US20210207205A1
公开(公告)日：2021-07-08
申请号：US17209602
申请日：2021-03-23
Applicant: Nippon Sheet Glass Company, Limited , NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY , Go!Foton, Inc.
Inventor： Takashi FUKUZAWA , Hidenori NAGAI , Naofumi NISHIZAWA
Abstract: A PCR reaction vessel includes: a substrate; a channel formed on the substrate; a pair of filters, a first filter and a second filter, provided at respective ends of the channel; a pair of air communication ports, a first air communication port and a second air communication port, that communicate with the channel through the first filter and the second filter; a thermal cycle region formed between the first filter and the second filter in the channel; a branch point formed between the first filter and the second filter in the channel; a branched channel whose one end is connected to the branch point; and a sample introduction port formed at the other end of the branched channel.
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公开(公告)号：US12030049B2
公开(公告)日：2024-07-09
申请号：US16928938
申请日：2020-07-14
Applicant: Go!Foton, Inc.
Inventor： Takashi Fukuzawa , Osamu Kawaguchi , Hidemitsu Takeuchi
CPC classification number: B01L3/502738 , B01L3/502723 , B01L3/50273 , B01L7/525 , B01L2200/0684 , B01L2300/048 , B01L2300/0654 , B01L2300/0681 , B01L2300/0867 , B01L2300/0883 , B01L2300/14 , B01L2300/1822 , B01L2300/1827 , B01L2400/0487 , B01L2400/0622 , B01L2400/0666 , B01L2400/0694
Abstract: A reaction processing apparatus includes: a reaction processing vessel; a temperature control system; and a liquid feeding system. The liquid feeding system includes: a pump having a discharge port; a first air channel; a second air channel; a first three-way valve capable of being switched between a state in which a first air communication port communicates with the discharge port and a state in which the first air communication port is opened to the atmospheric pressure; a second three-way valve capable of being switched between a state in which a second air communication port communicates with the discharge port and a state in which the second air communication port is opened to the atmospheric pressure; and a CPU that controls these components.
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公开(公告)号：US11827924B2
公开(公告)日：2023-11-28
申请号：US17209602
申请日：2021-03-23
Applicant: Nippon Sheet Glass Company, Limited , NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY , Go!Foton, Inc.
Inventor： Takashi Fukuzawa , Hidenori Nagai , Naofumi Nishizawa
IPC: C12P19/34 , C12Q1/6848 , G01N37/00 , C12M1/00 , G01N35/08 , B01L3/00 , B01L7/00 , C12Q1/686 , G01N21/64
CPC classification number: C12Q1/6848 , B01L3/502 , B01L7/52 , C12M1/00 , C12Q1/686 , G01N21/64 , G01N35/08 , G01N37/00 , B01L2200/0689 , B01L2300/0681 , B01L2300/0883 , B01L2300/14 , B01L2400/0487
Abstract: A PCR reaction vessel includes: a substrate; a channel formed on the substrate; a pair of filters, a first filter and a second filter, provided at respective ends of the channel; a pair of air communication ports, a first air communication port and a second air communication port, that communicate with the channel through the first filter and the second filter; a thermal cycle region formed between the first filter and the second filter in the channel; a branch point formed between the first filter and the second filter in the channel; a branched channel whose one end is connected to the branch point; and a sample introduction port formed at the other end of the branched channel.
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公开(公告)号：US20250065337A1
公开(公告)日：2025-02-27
申请号：US18941069
申请日：2024-11-08
Applicant: Go!Foton, Inc.
Inventor： Hiroki YABU , Toshinori MOTONO , Osamu KAWAGUCHi
Abstract: A microfluidic chip includes: a substrate; a channel that is formed on the substrate and that is for a sample to move; a first air coupling port that is provided at an end of the channel; a thermal cycle region that is provided in a part of the channel and that is for applying a thermal cycle to the sample in the channel; and a first chamber that is provided between the thermal cycle region and the first air coupling port in the channel.
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公开(公告)号：US20230256432A1
公开(公告)日：2023-08-17
申请号：US18020223
申请日：2021-08-05
Applicant: Go!Foton, Inc.
Inventor： Takashi FUKUZAWA
IPC: B01L3/00
CPC classification number: B01L3/502715 , B01L3/502761 , B01L2300/0816 , B01L2300/0681 , B01L2200/10 , B01L2300/0861 , B01L2300/041 , B01L2300/161
Abstract: In a nucleic acid extraction container, a filter part includes: a hydrophilic filter for collecting biological materials containing a nucleic acid from a sample; a biological material collection area for collecting biological materials on the filter; and a sample permeation area for allowing the passage of a sample having permeated through the filter. A sample injection port communicates with the biological material collection area. An air communication port communicates with the biological material collection area. A sample discharge port communicates with the sample permeation area. The air communication port is configured so as to be outwardly openable and closable.
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