摘要:
Indoles having aryloxyalkanoic acid substituents or arylalkanoic acid substituents are agonists or partial agonists of PPAR gamma and are useful in the treatment and control of hyperglycemia that is symptomatic of type II diabetes, as well as dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity that are often associated with type 2 diabetes.
摘要:
Indoles having aryloxyalkanoic acid substituents or arylalkanoic acid substituents are agonists or partial agonists of PPAR gamma and are useful in the treatment and control of hyperglycemia that is symptomatic of type II diabetes, as well as dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity that are often associated with type 2 diabetes.
摘要:
Indoles having aryloxyalkanoic acid substituents or arylalkanoic acid substituents are agonists or partial agonists of PPAR gamma and are useful in the treatment and control of hyperglycemia that is symptomatic of type II diabetes, as well as dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, and obesity that are often associated with type 2 diabetes.
摘要:
This invention relates to the use of potent potassium channel blockers or a formulation thereof in the treatment of glaucoma and other conditions which leads to elevated intraoccular pressure in the eye of a patient. This invention also relates to the use of such compounds to provide a neuroprotective effect to the eye of mammalian species, particularly humans.
摘要:
An antenna having a central active element and a plurality of passive dipoles surrounding the active element is disclosed. The passive dipoles increase the antenna gain by increasing the radiated energy in the azimuth direction. In another embodiment a plurality of parasitic directing elements extend radially outward from the passive dipoles.
摘要:
An antenna includes a ground plane and an active antenna element adjacent the ground plane. Passive antenna elements are adjacent the ground plane, and are spaced apart from the active antenna element. First parasitic gratings are adjacent the ground plane and are spaced apart from the active antenna element. Each first parasitic grating is between two adjacent passive antenna elements. A controller selectably controls the passive antenna elements for operating in a reflective mode or a directive mode. The controller includes for each respective passive antenna element at least one impedance element connected to the ground plane, and a switch adjacent the ground plane for connecting the at least one impedance element to the passive antenna element so that the passive antenna element operates in the reflective or directive mode.
摘要:
A mechanical system for feeding cut sheet paper to a printer from one of several cassettes. A mechanical selector is mounted in each cassette so that it can drive a paper feed roll mounted in that cassette. The cassettes include insert guides which allow each cassette to be replaceably mounted in at least one side rail secured on the printer. The side rail has guides that receive and automatically locate each cassette on the printer with a simple "drop in" engagement. The side rail supports a gear train or an equivalent power transmission arrangement that has a common drive and extends to all of the cassettes. A power input gear of each selector engages an associated gear of the gear train. The selectors each include a combination mechanism that allows the selector to transmit power only after the drive shaft has supplied a programmed pattern of rotations and counter-rotations to the selectors. A unique association between the programmed pattern of rotations and the selection of a given cassette is established either by varying the "combinations" of the selectors or by using the same combination but varying the gear ratio between the drive shaft and the power input gear of the selector.
摘要:
The present invention is directed to a bicyclic heteroaryl benzamide compounds of formula (I) which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence are useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor TrkA.