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    Pipette tip and a method for pipetting a congealed blood sample utilizing the pipette tip
    2.
    发明授权
    Pipette tip and a method for pipetting a congealed blood sample utilizing the pipette tip 有权
    移液管吸头和使用移液管吸头移液凝血血样的方法

    公开(公告)号：US08460617B2

    公开(公告)日：2013-06-11

    申请号：US12512171

    申请日：2009-07-30

    申请人： Gottlieb Schacher ,  Rolf Schneebeli ,  Hans-Peter Wahl

    发明人： Gottlieb Schacher ,  Rolf Schneebeli ,  Hans-Peter Wahl

    IPC分类号： B01L3/02

    CPC分类号： B01L3/0275 ,  B01L2200/026 ,  Y10T436/2575

    摘要： A pipette tip and a method for pipetting a congealed blood sample utilizing the pipette tip are disclosed. The pipette tip includes an attachment section configured to be attached to a dispensing device, a liquid containing section configured to receive at least part of an aspired liquid sample, and a liquid aspiration section that is connected to the liquid containing section. The liquid aspiration section has a distal end aspiration opening and at least one further aspiration opening in a side wall.

    摘要翻译： 公开了移液管尖端和利用移液管吸头移液凝血血样的方法。 移液管末端包括被配置为附接到分配装置的附接部分，构造成容纳至少一部分吸取的液体样品的液体容纳部分和连接到液体容纳部分的液体抽吸部分。 液体抽吸部分具有远端抽吸开口和在侧壁中的至少一个另外的抽吸开口。

    Apparatus for Performing Nucleic Acid Analysis
    5.
    发明申请
    Apparatus for Performing Nucleic Acid Analysis 审中-公开
    用于进行核酸分析的装置

    公开(公告)号：US20090227006A1

    公开(公告)日：2009-09-10

    申请号：US12373276

    申请日：2007-07-05

    申请人： Martin Kopp ,  Hans-Peter Wahl ,  Emad Sarofim ,  Oliver Elsenhans ,  Goran Savatic ,  Roland Christof Hutter

    发明人： Martin Kopp ,  Hans-Peter Wahl ,  Emad Sarofim ,  Oliver Elsenhans ,  Goran Savatic ,  Roland Christof Hutter

    IPC分类号： C12M1/00

    CPC分类号： B01L3/502715 ,  G01N35/0099 ,  G01N2035/00346

    摘要： The embodiments of the present invention are directed to an automatic apparatus (55), which is designed for performing nucleic acid analysis, optionally including sample preparation, with integrated disposable sample holding and processing devices (1), which devices (1) comprise a sample to be analyzed with the apparatus (55). The apparatus (55) comprises workstations (17, 40) for receiving, holding and processing such integrated disposable devices (1), a reagents station (56) for reagents (25), transfer means (36) for performing movements of an actuator, fluid actuation means for processing the sample (32) and reagents in said disposable devices (1), temperature control means (37) for heating or cooling, detection means for measuring a property of the processed samples (32), and control means for controlling the sample (32) preparation, the handling of the disposable devices (1) and the sample analysis performed by the apparatus (55).

    摘要翻译： 本发明的实施例涉及一种自动装置（55），其被设计用于执行核酸分析，任选地包括样品制备，具有集成的一次性样品保持和处理装置（1），所述装置（1）包括样品 用装置（55）进行分析。 装置（55）包括用于接收，保持和处理这种集成的一次性装置（1），用于试剂（25）的试剂台（56），用于执行致动器的运动的传送装置（36） 用于处理所述一次性装置（1）中的样品（32）和试剂的流体致动装置，用于加热或冷却的温度控制装置（37），用于测量经处理样品（32）的性质的检测装置，以及用于控制 样品（32）制备，一次性装置（1）的处理和由装置（55）进行的样品分析。

    PLASMA SEPARATION DEVICE AND METHOD THEREOF
    6.
    发明申请
    PLASMA SEPARATION DEVICE AND METHOD THEREOF 审中-公开
    等离子体分离装置及其方法

    公开(公告)号：US20080290048A1

    公开(公告)日：2008-11-27

    申请号：US12131512

    申请日：2008-06-02

    申请人： Rainer Jaeggi ,  Patrick Griss ,  Hans-Peter Wahl

    发明人： Rainer Jaeggi ,  Patrick Griss ,  Hans-Peter Wahl

    IPC分类号： B04B3/00 ,  B01D33/15 ,  G01N21/07 ,  G01N33/48

    CPC分类号： G01N21/07 ,  B01L3/502746 ,  B01L3/502753 ,  B01L2300/0806 ,  B01L2300/0816 ,  B01L2300/0858 ,  B01L2300/0864 ,  B01L2400/0409 ,  B01L2400/086 ,  G01N33/491

    摘要： A device and method thereof for at least partially fractioning or separating fluid from higher density and/or solid particles contained in liquid samples are disclosed. The present invention provides a movable or drivable device having a flow path defined by inner and outer wall surfaces and arranged such that the flow velocity of the liquid sample along the outer wall surface is higher than the flow velocity along the opposite inner wall surface. The flow path provides elements to at least delay the flow of the liquid sample along the outer wall surface. The device is, e.g., suitable for the separation of blood, e.g., of plasma from at least red blood cells, and from red and white blood cells to achieve blood plasma with high purity for analytical reasons.

    摘要翻译： 公开了一种用于至少部分地分馏或分离液体样品中包含的较高密度和/或固体颗粒的流体的装置及其方法。 本发明提供了一种可移动或可驱动的装置，其具有由内壁和外壁表面限定的流动路径，并且布置成使得液体样品沿着外壁表面的流速高于沿着相对的内壁表面的流速。 流动路径提供元件以至少延迟液体样品沿着外壁表面的流动。 例如，该装置适于从至少红细胞和红细胞和白细胞分离血液，例如血浆，以实现高纯度的血浆，用于分析的原因。

    DEVICE WITH INSERT FOR ANALYTICAL SYSTEMS
    7.
    发明申请
    DEVICE WITH INSERT FOR ANALYTICAL SYSTEMS 审中-公开
    具有分析系统插入的设备

    公开(公告)号：US20080011062A1

    公开(公告)日：2008-01-17

    申请号：US11776367

    申请日：2007-07-11

    申请人： Emad Sarofim ,  Hans-Peter Wahl

    发明人： Emad Sarofim ,  Hans-Peter Wahl

    IPC分类号： G01N1/28

    CPC分类号： B01L3/502715 ,  B01L3/5025 ,  B01L2400/0622 ,  B01L2400/0633

    摘要： A analytical device comprising a body comprising a fluidic unit comprising a first chamber having an outlet opening and a first channel exiting said outlet opening, wherein said first chamber further contains an insert comprising recesses between ribs touching the walls of said first chamber and a second channel, said insert being located in a first position wherein said insert is not engaged with said outlet opening, said insert being moveable from said first position to a second position within said first chamber, wherein said insert is engaged with said outlet opening such that said second channel extends said first channel into said first chamber and in the part pointing towards said outlet opening resembles the shape of said first chamber.

    摘要翻译： 一种包括主体的分析装置，包括流体单元，所述流体单元包括具有出口开口的第一室和离开所述出口开口的第一通道，其中所述第一室还包含插入件，所述插入件包括接触所述第一室的壁的肋之间的凹部， 所述插入件位于第一位置，其中所述插入件不与所述出口开口接合，所述插入件可从所述第一位置移动到所述第一室内的第二位置，其中所述插入件与所述出口开口接合，使得所述第二 通道将所述第一通道延伸到所述第一室中，并且指向所述出口的部分类似于所述第一室的形状。

    Devices and Process for Separating Plasma From a Blood Sample
    9.
    发明申请
    Devices and Process for Separating Plasma From a Blood Sample 审中-公开
    从血液样品中分离血浆的装置和方法

    公开(公告)号：US20120088227A1

    公开(公告)日：2012-04-12

    申请号：US13082646

    申请日：2011-04-08

    申请人： Tomas Gruebl ,  Michael Heinrich ,  Roger Sandoz ,  Emad Sarofim ,  Hans-Peter Wahl

    发明人： Tomas Gruebl ,  Michael Heinrich ,  Roger Sandoz ,  Emad Sarofim ,  Hans-Peter Wahl

    IPC分类号： B01D43/00 ,  C12Q1/70

    CPC分类号： G01N33/491 ,  B01L3/5023 ,  B01L2200/028 ,  B01L2300/043 ,  B01L2300/0681 ,  B01L2300/069 ,  B01L2400/0406

    摘要： The present invention pertains to a device for separating plasma from a blood sample comprising a stacked structure which is provided with a first portion including a separating member having a first surface for applying or receiving the blood sample, wherein the separating member is adapted to permit the passage of plasma but to inhibit the passage of cells, and a second portion including an absorptive member for absorbing the plasma, which has a second surface in contact with the separating member for receiving the plasma, wherein the absorptive member is adapted to generate a capillary pressure so as to draw plasma from the separating member to the absorptive member. The first portion is fixed to the backing member in a manner to be removed without destroying the absorptive member. The absorptive member is fixed to the backing member in a manner to be removed without destroying the absorptive member.

    摘要翻译： 本发明涉及一种用于从血液样品分离血浆的装置，包括层叠结构，该层叠结构设置有包括具有用于施加或接收血液样本的第一表面的分离构件的第一部分，其中分离构件适于允许 等离子体通过，但是抑制细胞通过，第二部分包括用于吸收等离子体的吸收部件，该第二部分具有与用于接收等离子体的分离部件接触的第二表面，其中吸收部件适于产生毛细管 压力以将等离子体从分离构件吸入吸收构件。 第一部分以不被破坏吸收构件的方式被移除而固定到背衬构件上。 吸收构件以不会破坏吸收构件的方式被移除而固定到背衬构件上。