FLOW SIMULATION IN A WELL OR PIPE
    1.
    发明申请
    FLOW SIMULATION IN A WELL OR PIPE 有权
    在一个井或管道中的流动模拟

    公开(公告)号:US20090294122A1

    公开(公告)日:2009-12-03

    申请号:US12302231

    申请日:2006-05-24

    摘要: A method of simulating fluid transport in a system for stimulating a well in a material formation of a resource reservoir, the system comprising a conduit element arranged in said well, the conduit element comprising a conduit wall including one or more openings for discharging a fluid into the material formation surrounding the conduit element; the method comprising establishing and numerically processing a transport model of fluid transport inside the conduit element. The transport model further includes a model of fluid transport in a predetermined space around said conduit element.

    摘要翻译: 一种在用于在资源储存器的材料形成中刺激井的系统中的流体输送的模拟方法,所述系统包括布置在所述井中的管道元件,所述管道元件包括导管壁,所述导管壁包括用于将流体排出的一个或多个开口 围绕导管元件的材料形成; 该方法包括建立和数字处理导管元件内的流体输送的运输模型。 运输模型还包括围绕所述导管元件的预定空间中的流体输送模型。

    Potent LNA oligonucleotides for the inhibition of HIF-1a expression
    2.
    发明申请
    Potent LNA oligonucleotides for the inhibition of HIF-1a expression 有权
    用于抑制HIF-1a表达的强大的LNA寡核苷酸

    公开(公告)号:US20060252721A1

    公开(公告)日:2006-11-09

    申请号:US11271686

    申请日:2005-11-09

    IPC分类号: A61K48/00 C07H21/02

    摘要: The present disclosure relates to an LNA oligonucleotide consisting of a sequence selected from the group consisting of 5′-(Tx)GxGxcsasasgscsastscscsTxGxT-3′ and 5′-(Gx)TxTxascstsgscscststscsTxTxA-3′, wherein capital letters designate a beta-D-oxy-LNA nucleotide analogue, small letters designate a 2-deoxynucleotide, underline designates either a beta-D-oxy-LNA nucleotide analogue or a 2-deoxynucleotide, subscript “s” designates a phosphorothioate link between neighbouring nucleotides/LNA nucleotide analogues, and subscript “x” designates either a phosphorothioate link or a phosphorodiester link between neighbouring nucleotides/LNA nucleotide analogues, and wherein the sequence is optionally extended by up to five 2-deoxynucleotide units. The LNA oligonucleotides are useful for modulating the expression of hypoxia-inducible factor-1a (HIF-1a), e.g. in the treatment of cancer diseases, inhibiting angiogenesis, inducing apoptosis, preventing cellular proliferation, or treating an angiogenic disease, e.g. diabetic retinopathy, macular degeneration (ARMD), psoriasis, rheumatoid arthritis and other inflammatory diseases.

    摘要翻译: 本公开内容涉及由选自下组的序列组成的LNA寡核苷酸:5' - (T x)X G x 例如,本发明的一个或多个实施方案,其中, x> T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T T -3'和5' - (G x x)T x x T x 其中一个或多个第一个或更多个> 其中大写字母表示β-D-氧基,其中大写字母表示β-D-氧基, -LNA核苷酸类似物,小写字母表示2-脱氧核苷酸,下划线表示β-D-氧-LNA核苷酸类似物或2-脱氧核苷酸,下标“s”表示相邻核苷酸/ LNA核苷酸类似物之间的硫代磷酸酯连接,下标 “x”表示相邻核苷酸/ LNA核苷酸类似物之间的硫代磷酸酯连接或磷酸二酯连接,并且其中该序列是选择性的 最多延伸5个2-脱氧核苷酸单位。 LNA寡核苷酸可用于调节缺氧诱导因子-1a(HIF-1a)的表达,例如, 在治疗癌症疾病,抑制血管发生,诱导细胞凋亡,预防细胞增殖或治疗血管生成疾病,例如, 糖尿病性视网膜病变,黄斑变性(ARMD),牛皮癣,类风湿性关节炎等炎症性疾病。

    Flexible bag in the box container for liquids
    4.
    发明授权
    Flexible bag in the box container for liquids 失效
    用于液体的盒式容器中的柔性袋

    公开(公告)号:US06227439B1

    公开(公告)日:2001-05-08

    申请号:US09323874

    申请日:1999-06-01

    申请人: Henrik Hansen

    发明人: Henrik Hansen

    IPC分类号: B65D536

    摘要: Liquid resistant containers having double walled construction and an upwardly projecting container bottom are suitable for use, e.g., as a flower vase. Preferably, the containers are formed from a unitary carton blank having fold lines such that the container is prepared by folding the blank along fold lines to form the open-ended container, the cavity of which is lined with a liner or open bag to provide further resistance against leaks.

    摘要翻译: 具有双壁结构和向上突出的容器底部的耐液体容器适合用作例如花瓶。 优选地,容器由具有折叠线的整体纸箱坯料形成,使得容器通过沿着折叠线折叠坯料来制备,以形成开口容器,其空腔内衬有衬里或开放袋,以进一步提供 抵抗泄漏。

    Method and a system for controlling tension of paper and foil webs
    5.
    发明授权
    Method and a system for controlling tension of paper and foil webs 有权
    用于控制纸张和纸幅的张力的方法和系统

    公开(公告)号:US06193184B1

    公开(公告)日:2001-02-27

    申请号:US09297059

    申请日:1999-04-29

    申请人: Per Henrik Hansen

    发明人: Per Henrik Hansen

    IPC分类号: B65H2318

    摘要: In connection with the unreeling of a paper or foil web from a supply reel, e.g. in a flowpacking machine, it is well known to move the web through an adjustment station for maintaining a constant tension of the web in the outer length thereof. Normally, this is achieved by the use of a synchronously driven unreeling roller partially entwined by the web and a system for adjusting the degree of entwining based on a current detection of the web tension. With the invention this is simplified by driving the unreeling roller with a peripheral speed noticeably higher than the web speed, whereby it is possible with a suitable angle of entwining to achieve both a relatively low web tension and an automatically self-adjusting, constant web tension. By virtue of the associated, rather low dynamic friction between the roller and the web, it is even possible to effectively control or maintain the lateral positioning of the web merely by the use of simple abutments for co-operation with the side edges of the web.

    摘要翻译: 关于纸或箔片从供应卷轴的松开,例如。 在开袋机中,众所周知,将幅材移动通过调节台,以在幅材的外部长度上保持幅材的恒定张力。 通常,这通过使用部分地卷绕在卷筒纸上的同步驱动的卷取辊和用于基于卷筒纸张力的当前检测来调节缠结程度的系统来实现。 通过本发明,通过以明显高于幅材速度的圆周速度驱动退卷辊来简化本发明,由此可以以适当的缠绕角度实现相对较低的幅材张力和自动自调整的卷材张力 。 由于辊和纸幅之间相关联的相当低的动态摩擦,甚至可以通过使用简单的支座来与纸幅的侧边缘配合来有效地控制或维持幅材的横向定位 。

    Balloon folding apparatus, methods and products
    7.
    发明授权
    Balloon folding apparatus, methods and products 有权
    气球折叠仪,方法及产品

    公开(公告)号:US07951164B2

    公开(公告)日:2011-05-31

    申请号:US10087303

    申请日:2002-02-28

    IPC分类号: A61M29/00

    摘要: A medical balloon may be configured by at least partially inflating the medical balloon and forming at least one primary lobe in the balloon. The primary lobe extends from a central portion of the balloon. The primary lobe may be manipulated to form at least two secondary lobes therefrom. The balloon may then be deflated and the secondary lobes wrapped around the balloon.

    摘要翻译: 医疗气囊可以通过至少部分地使医疗气囊膨胀并且在气囊中形成至少一个主瓣来构造。 主瓣从球囊的中心部分延伸。 主瓣可以被操纵以从其形成至少两个副瓣。 然后可以将气球收缩,并且副瓣缠绕在气球周围。

    Process and apparatus for the preparation of synthesis gas
    8.
    发明申请
    Process and apparatus for the preparation of synthesis gas 有权
    用于制备合成气的方法和装置

    公开(公告)号:US20060143984A1

    公开(公告)日:2006-07-06

    申请号:US11359466

    申请日:2006-02-23

    摘要: Process and apparatus for the preparation of synthesis gas by catalytic steam and/or CO2 reforming of a hydrocarbon feedstock comprising the following steps: (a) heating the reaction mixture of hydrocarbon and steam and/or CO2 in a heated steam reforming unit integrated with the flue gas containing waste heat section from the fired tubular reformer in which reforming of the reaction mixture takes place by contact with a solid reforming catalyst (b) feeding the partially steam reformed mixture to the fired tubular reformer and further reforming the mixture to the desired composition and temperature, wherein the heated steam reforming unit comprises a piping system containing reaction sections with solid reforming catalyst comprising catalyst pellets and/or catalysed structured elements, the piping system being part of the process gas piping system integrated with the flue gas-containing waste heat section.

    摘要翻译: 通过烃原料的催化蒸汽和/或CO 2重整制备合成气的方法和装置,包括以下步骤:(a)加热烃和蒸汽和/或CO的反应混合物, 在与来自燃烧的管状重整器的含有废热部分的废气的一体化的加热蒸汽重整单元中,其中反应混合物的重整通过与固体重整催化剂(b)接触而进行的,所述固体重整催化剂(b) 重整混合物到烧制的管式重整器中,并进一步将混合物重整成所需的组成和温度,其中加热的蒸汽重整单元包括含有反应段的管道系统,固体重整催化剂包含催化剂颗粒和/或催化的结构化元素,管道系统 与含烟气的废热段集成的工艺气体管道系统的一部分。

    Method of operating a turbine
    9.
    发明授权
    Method of operating a turbine 失效
    运行涡轮机的方法

    公开(公告)号:US06840734B2

    公开(公告)日:2005-01-11

    申请号:US10204854

    申请日:2001-03-08

    IPC分类号: F03D7/02 F03D7/04 F01B25/26

    摘要: A method of controlling the speed of rotation of a turbine, the turbine comprising a rotor, the method comprising the steps of measuring or estimating power or torque related to the energy production of the turbine, processing the measured or estimated power or torque so as to obtain a corresponding rotational speed, comparing the obtained rotational speed to a first predefined threshold value and to a second predefined threshold value, the second predefined threshold value being larger than the first predefined threshold value, and controlling the speed of rotation of the rotor according to the obtained rotational speed, so as to obtain a predetermined energy production from the turbine, and in such a way that in case the obtained rotational speed does not exceed the first predefined threshold value, the predetermined energy production from the turbine is optimal, in case the obtained rotational speed exceeds the first predefined threshold value, but does not exceed the second predefined threshold value, the predetermined energy production from the turbine is optimal, in case the obtained rotational speed exceeds the second predefined threshold value, the speed of rotation of the rotor of the turbine is reduced in a predefined manner to a value corresponding to the first predefined threshold value.

    摘要翻译: 一种控制涡轮转速的方法,所述涡轮机包括转子,所述方法包括以下步骤:测量或估计与所述涡轮机的能量产生相关的功率或扭矩,处理所测量或估计的功率或扭矩,以便 获得相应的转速,将获得的转速与第一预定义阈值和第二预定义阈值进行比较,第二预定义阈值大于第一预定义阈值,并根据转速控制转子的转速 获得的转速,以便从涡轮机获得预定的能量产生,并且使得在获得的转速不超过第一预定阈值的情况下,来自涡轮机的预定能量产生是最佳的,在情况下 所获得的转速超过第一预定义阈值,但不超过第二预定义阈值 在获得的转速超过第二预定阈值的情况下,来自涡轮机的预定能量产生是最佳的,涡轮机的转子的旋转速度以预定的方式减小到对应于第一 预定阈值。

    System for optimizing the production of a milk producing animal herd
    10.
    发明授权
    System for optimizing the production of a milk producing animal herd 有权
    用于优化产奶动物群的生产性能的系统

    公开(公告)号:US06814025B2

    公开(公告)日:2004-11-09

    申请号:US10091782

    申请日:2002-03-07

    IPC分类号: A01J5007

    CPC分类号: A01K1/12 A01J5/01 A01K11/006

    摘要: A system for optimising the production performance of a milk producing animal herd is provided. The system comprises a milk sampling apparatus, an analytical apparatus comprising separate equipment for analyzing compounds or parameters that in the presence of compounds indicative of the physiological or nutritional condition of the herd member, generates detectable signals, and apparatus directing a part of the milk sample (directing apparatus) to each separate equipment, which is controlled by data for the physiological and nutritional state of a herd member, so that the directing apparatus is only activated at pre-selected points in time or at pre-selected time intervals in the production and/or lactation cycles. Specific compounds are compounds indicative of mastitis, including beta-N-acetylhexosaminidase (NAGase) E.C. 3.2.1.52 and lactate dehydrogenase (LDH), protein balance, including milk urea nitrogen (MUN) and total protein, ketosis, including acetolactate, beta-hydroxybutyrate, acetone and lipids, fat and state in reproduction cycle, including a steroid or peptide hormone, e.g., progesterone. Furthermore, the system comprises equipment for signal detection to record and process the signals, equipment to store data and equipment to produce data output. Methods for optimizing the production performance of a milk producing animal herd and an apparatus therefor.

    摘要翻译: 提供了一种用于优化产奶动物群体的生产性能的系统。 该系统包括牛奶取样装置,分析装置包括用于分析化合物或参数的分离设备,所述化合物或参数在存在指示群体的生理或营养状况的化合物的存在下产生可检测的信号,以及引导部分乳样品的装置 (定向装置)到每个单独的设备,其由用于群体成员的生理和营养状态的数据控制,使得定向装置仅在预先选择的时间点或在生产中以预选的时间间隔激活 和/或哺乳期。 特定化合物是指示乳腺炎的化合物,包括β-N-乙酰基己糖胺酶(NAGase)EC 3.2.1.52和乳酸脱氢酶(LDH),蛋白质平衡,包括乳尿素氮(MUN)和总蛋白质,酮症,包括乙酰乳酸,β-羟基丁酸 ,丙酮和脂质,脂肪和繁殖周期的状态,包括类固醇或肽激素,例如孕酮。 此外,该系统包括用于信号检测的设备,用于记录和处理信号,设备存储数据和设备以产生数据输出。 用于优化生产奶牛的生产性能的方法及其设备。