Abstract:
The present disclosure related to an apparatus that may be used for taking blood glucose measurements and providing individualized insulin dose recommendations wherein the apparatus is easy to use and facilitates improved diabetes control in patients. Also disclosed are related methods.
Abstract:
A method to generate and save a resource representation recited by a request encoded in a computer algorithm, wherein the method receives from a requesting algorithm an Unresolved resource request. The method resolves the resource request to an endpoint and evaluates the resolved resource request by the endpoint to generate a resource representation. The method further generates and saves in a cache at least one Unresolved request scope key, a resolved request scope key, and a cache entry comprising the resource representation. The method associates the cache entry with the resolved request scope key and with the at least one Unresolved request scope key using a mapping function encoded in the cache.
Abstract:
A method for manufacturing a portion of an enzymatic electrochemical-based sensor includes applying a water-miscible conductive ink to a substrate of an enzymatic electrochemical-based sensor. The water-miscible conductive ink includes a conductive material, an enzyme, a mediator, and a binding agent (that becomes operatively water-insoluble upon drying) formulated as a water-miscible aqueous-based dispersion. The method further includes the drying the water-miscible conductive ink to form a conductive layer on the substrate that includes an operatively water-insoluble binding agent.
Abstract:
The present invention provides compounds that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases and cancer.
Abstract:
Monitoring systems and protocols are disclosed that are flexible in mode operation and format depending on the environment in which they are used. Such monitoring systems and protocols are able to change their utilization automatically, or by received instruction to do so. A location detection system includes one or more low frequency transmitters, one or more radio frequency monitoring tags and one or more receiving devices. The low frequency transmitter transmits location identification information, such as the transmitter ID, to a tag in the vicinity of the transmission. The tag relays the transmitter ID using a higher frequency transmission sent from the tag to the receiver. Communication protocols are disclosed that enable deciphering of multiple tag transmissions starting simultaneously.
Abstract:
Ionic hydrophilic high molecular weight redox polymers for use in enzymatic electrochemical-based sensors include a hydrophilic polymer (such as a hydrophilic polymer backbone) with ionic portions (e.g., cationic monomers incorporated in the hydrophilic polymer backbone) and a plurality of attached redox mediators. The redox mediators can be, for example, covalently attached to the hydrophilic polymer in a pendant manner. An exemplary cationic hydrophilic high molecular weight redox polymer is synthesized by co-polymerization of a hydrophilic acrylamide monomer, [2-(acryloyloxy)ethyl]trimethyl ammonium chloride and vinyl ferrocene.
Abstract:
A method for manufacturing an analysis module with accessible electrically conductive contact pads includes forming an insulating substrate with an upper surface, a microchannel(s) within the upper surface, and electrically conductive contact pad(s) disposed on the upper surface. The method also includes producing a laminate layer with a bottom surface, electrode(s) on the laminate layer bottom surface, and electrically conductive trace(s) on the laminate layer bottom surface. The method further includes adhering the laminate layer to the insulating substrate such that a portion of the bottom surface of the laminate layer is adhered to a portion of the upper surface of the insulating substrate, each electrode is exposed to at least one microchannel; and each electrically conductive trace is electrically contacted to at least one electrically conductive contact pad. Furthermore, the adhering is such that at least one surface of the electrically conductive contact pad remains exposed and accessible for electrical connection.
Abstract:
A drilling tool including a tool body and a cutter pocket formed in the tool body, the cutter pocket including a front planar surface, a back planar surface opposite the front planar surface, a first side surface between the front and back planar surfaces, and a second side surface opposite the first side surface and between the front and back planar surfaces is disclosed herein. A method of manufacturing a drilling tool including machining a tool body having a cutter pocket in accordance with embodiments disclosed herein, disposing a cutting element in the cutter pocket, and brazing the cutting element in the cutter pocket is disclosed.
Abstract:
A method comprises receiving a bit sequence associated with at least one file, the bit sequence comprising payload data in a compressed format and characterization data that maps the compressed format of the payload data. The method continues by encrypting the characterization data that maps the compressed format of the payload data. The method concludes by transmitting the bit sequence such that the characterization data is encrypted and at least a portion of the payload data is unencrypted.
Abstract:
An object identification system includes a monitor and a plurality of transceivers that communicate over a common medium. The monitor includes a first transmitter, a first receiver, and a processor. Each transceiver includes a resonant circuit, a transmitter, a receiver, and an antenna coupled to the resonant circuit. The processor performs a method for performing transceiver communication that includes the steps of: (a) transmitting from the first transmitter a first frequency for a first duration; (b) after lapse of the first duration, receiving via the first receiver a response signal from at least one of the resonant circuits; (c) determining a second frequency from the received response signal; and (d) performing transceiver communication using the second frequency. Transceivers of the type having a resonant circuit coupled to an antenna, when operating in close proximity to each other, may interfere with the response from a single transceiver by absorbing the energy intended to be received by the transceiver, absorbing the energy transmitted by the transceiver, or altering the resonant frequency of the resonant circuit. By determining the second frequency for transceiver communication, the monitor may establish communication with the single transceiver at a frequency better suited for transferring operative power to the transceiver, conducting an interrogation protocol for identifying the transceiver, or for data transfer.