Spatially resolved ligand-receptor binding assays

    公开(公告)号:US10190986B2

    公开(公告)日:2019-01-29

    申请号:US13153934

    申请日:2011-06-06

    IPC分类号: G01N21/00 G01N21/64

    摘要: A method for analyzing the results of a ligand-receptor binding assay comprising the steps of: (a) providing the results of a ligand-receptor binding assay; and (b) qualifying the results of a ligand-receptor binding assay. More particularly, the ligand-receptor binding assay involves the steps of combining appropriate reagents in which receptors attached to a solid support, a sample suspected of containing a ligand, and a conjugate comprising a label form a complex in which the label is present at a concentration that is directly proportional to the amount of ligand present in the sample. Alternatively, the ligand-receptor binding assay involves the steps of combining appropriate reagents to perform a ligand-receptor binding assay in which receptors attached to a solid support, a sample suspected of containing a ligand, and a conjugate comprising a label form a complex in which the label is present at a concentration that is inversely proportional to the amount of analyte present in the sample.

    SPATIALLY RESOLVED LIGAND-RECEPTOR BINDING ASSAYS
    3.
    发明申请
    SPATIALLY RESOLVED LIGAND-RECEPTOR BINDING ASSAYS 审中-公开
    空间分辨的配体 - 受体结合测定

    公开(公告)号:US20120308997A1

    公开(公告)日:2012-12-06

    申请号:US13153934

    申请日:2011-06-06

    IPC分类号: C12Q1/68 G01N33/566

    CPC分类号: G01N21/6456

    摘要: A method for analyzing the results of a ligand-receptor binding assay comprising the steps of: (a) providing the results of a ligand-receptor binding assay; and (b) qualifying the results of a ligand-receptor binding assay. More particularly, the ligand-receptor binding assay involves the steps of combining appropriate reagents in which receptors attached to a solid support, a sample suspected of containing a ligand, and a conjugate comprising a label form a complex in which the label is present at a concentration that is directly proportional to the amount of ligand present in the sample. Alternatively, the ligand-receptor binding assay involves the steps of combining appropriate reagents to perform a ligand-receptor binding assay in which receptors attached to a solid support, a sample suspected of containing a ligand, and a conjugate comprising a label form a complex in which the label is present at a concentration that is inversely proportional to the amount of analyte present in the sample.

    摘要翻译: 用于分析配体 - 受体结合测定结果的方法,包括以下步骤:(a)提供配体 - 受体结合测定的结果; 和(b)限定配体 - 受体结合测定的结果。 更具体地,配体 - 受体结合测定包括合并适当的试剂的步骤,其中连接到固体支持物的受体,怀疑含有配体的样品和包含标记的缀合物形成复合物,其中标记物存在于 浓度与样品中存在的配体的量成正比。 或者,配体 - 受体结合测定包括合并试剂以进行配体 - 受体结合测定的步骤,其中连接到固体支持物的受体,怀疑含有配体的样品和包含标记的缀合物形成复合物 其标签以与样品中存在的分析物的量成反比的浓度存在。