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公开(公告)号：US08465953B2
公开(公告)日：2013-06-18
申请号：US12298216
申请日：2007-04-26
CPC分类号： C12N15/01 , C12N9/0051 , C12P7/06 , Y02E50/17
摘要： Non-recombinant bacteria that produce ethanol as the primary fermentation product, associated nucleic acids and polypeptides, methods for producing ethanol using the bacteria, and kits are disclosed.
摘要翻译： 公开了产生乙醇作为主要发酵产物，相关核酸和多肽的非重组细菌，使用细菌生产乙醇的方法和试剂盒。
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公开(公告)号：US20130098356A1
公开(公告)日：2013-04-25
申请号：US13583132
申请日：2011-03-10
申请人： Lonnie O. Ingram , Claudia C. Geddes , James J. Peterson , Michael T. Mullinnix , Keelnatham Shanmugam
发明人： Lonnie O. Ingram , Claudia C. Geddes , James J. Peterson , Michael T. Mullinnix , Keelnatham Shanmugam
IPC分类号： C12P19/14
CPC分类号： C12P19/14 , C12P19/02 , C12P2203/00
摘要： The invention provides methods for treatment of feedstock to reduce the relative viscosity and promote release of fermentable sugars.
摘要翻译： 本发明提供了用于处理原料以降低相对粘度并促进可发酵糖释放的方法。
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公开(公告)号：US09322043B2
公开(公告)日：2016-04-26
申请号：US13583132
申请日：2011-03-10
申请人： Lonnie O. Ingram , Claudia C. Geddes , James J. Peterson , Michael T. Mullinnix , Keelnatham Shanmugam
发明人： Lonnie O. Ingram , Claudia C. Geddes , James J. Peterson , Michael T. Mullinnix , Keelnatham Shanmugam
CPC分类号： C12P19/14 , C12P19/02 , C12P2203/00
摘要： The invention provides methods for treatment of feedstock to reduce the relative viscosity and promote release of fermentable sugars.
摘要翻译： 本发明提供了用于处理原料以降低相对粘度并促进可发酵糖释放的方法。
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公开(公告)号：US20100112656A1
公开(公告)日：2010-05-06
申请号：US12375484
申请日：2007-08-08
摘要： The invention provides recombinant bacteria, which comprise a full complement of heterologous ethanol production genes. Expression of the full complement of heterologous ethanol production genes causes the recombinant bacteria to produce ethanol as the primary fermentation product when grown in mineral salts medium, without the addition of complex nutrients. Methods for producing the recombinant bacteria and methods for producing ethanol using the recombinant bacteria are also disclosed.
摘要翻译： 本发明提供重组细菌，其包含全部异源乙醇生产基因。 异源乙醇生产基因的完整补体的表达导致重组细菌在无矿物质培养基中生长时产生乙醇作为主要的发酵产物，而不添加复杂的营养物质。 还公开了使用重组细菌生产重组细菌的方法和生产乙醇的方法。
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5.发明授权Materials and methods for the efficient production of acetate and other products 有权有效生产乙酸酯等产品的材料和方法公开(公告)号：US07977075B2
公开(公告)日：2011-07-12
申请号：US12235074
申请日：2008-09-22
IPC分类号： C12N1/20 , C12N9/00 , C12N9/04 , C12N9/02 , C12N9/10 , C12N9/14 , C12Q1/68 , C07H21/04 , C07H21/02 , C12P7/00
CPC分类号： C12N9/001 , C12N9/0006 , C12N9/0008 , C12N9/1029 , C12N9/14 , C12P7/40 , C12P7/54 , Y02E50/17
摘要： The subject invention provides materials and methods wherein unique and advantageous combinations of gene mutations are used to direct carbon flow from sugars to a single product. The techniques of the subject invention can be used to obtain products from native pathways as well as from recombinant pathways. In preferred embodiments, the subject invention provides new materials and methods for the efficient production of acetate and pyruvic acid.
摘要翻译： 本发明提供的材料和方法，其中使用基因突变的独特且有利的组合来引导碳从碳流到单一产物。 本发明的技术可以用于从天然途径以及重组途径获得产物。 在优选的实施方案中，本发明提供了用于有效制备乙酸酯和丙酮酸的新材料和方法。
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公开(公告)号：US08716002B2
公开(公告)日：2014-05-06
申请号：US12375484
申请日：2007-08-08
摘要： The invention provides recombinant bacteria, which comprise a full complement of heterologous ethanol production genes. Expression of the full complement of heterologous ethanol production genes causes the recombinant bacteria to produce ethanol as the primary fermentation product when grown in mineral salts medium, without the addition of complex nutrients. Methods for producing the recombinant bacteria and methods for producing ethanol using the recombinant bacteria are also disclosed.
摘要翻译： 本发明提供重组细菌，其包含全部异源乙醇生产基因。 异源乙醇生产基因的完整补体的表达导致重组细菌在无矿物质培养基中生长时产生乙醇作为主要的发酵产物，而不添加复杂的营养物质。 还公开了使用重组细菌生产重组细菌的方法和生产乙醇的方法。
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7.发明授权Materials and methods for the efficient production of acetate and other products 有权有效生产乙酸酯等产品的材料和方法公开(公告)号：US08383374B2
公开(公告)日：2013-02-26
申请号：US13154765
申请日：2011-06-07
IPC分类号： C12P7/00 , C12N9/00 , C12N9/02 , C12N9/10 , C12N9/14 , C12N1/20 , C12Q1/68 , C07H21/04 , C07H21/02 , C12N9/04
CPC分类号： C12N9/001 , C12N9/0006 , C12N9/0008 , C12N9/1029 , C12N9/14 , C12P7/40 , C12P7/54 , Y02E50/17
摘要： The subject invention provides materials and methods wherein unique and advantageous combinations of gene mutations are used to direct carbon flow from sugars to a single product. The techniques of the subject invention can be used to obtain products from native pathways as well as from recombinant pathways. In preferred embodiments, the subject invention provides new materials and methods for the efficient production of acetate and pyruvic acid.
摘要翻译： 本发明提供的材料和方法，其中使用基因突变的独特且有利的组合来引导碳从碳流到单一产物。 本发明的技术可以用于从天然途径以及重组途径获得产物。 在优选的实施方案中，本发明提供了用于有效制备乙酸酯和丙酮酸的新材料和方法。
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8.发明申请公开(公告)号：US20120077241A1
公开(公告)日：2012-03-29
申请号：US13147155
申请日：2010-01-04
申请人： Elliot Norman Miller , Laura R. Jarboe , Lorraine P. Yomano , Sean W. York , Keelnatham Shanmugam , Lonnie O'Neil Ingram
发明人： Elliot Norman Miller , Laura R. Jarboe , Lorraine P. Yomano , Sean W. York , Keelnatham Shanmugam , Lonnie O'Neil Ingram
CPC分类号： C12P7/065 , C12N9/0008 , Y02E50/16 , Y02E50/17
摘要： The invention relates to bacterium that have increased resistance to furfural and methods of preparation. The invention also relates to methods of producing ethanol using the bacterium and corresponding kits.
摘要翻译： 本发明涉及具有增加的对糠醛的抗性和制备方法的细菌。 本发明还涉及使用细菌和相应试剂盒生产乙醇的方法。
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公开(公告)号：US20070037265A1
公开(公告)日：2007-02-15
申请号：US11501137
申请日：2006-08-08
申请人： Shengde Zhou , Lonnie Ingram , Keelnatham Shanmugam , Lorraine Yomano , Tammy Grabar , Jonathan Moore
发明人： Shengde Zhou , Lonnie Ingram , Keelnatham Shanmugam , Lorraine Yomano , Tammy Grabar , Jonathan Moore
摘要： The present invention provides derivatives of ethanologenic Escherichia coli K011 constructed for the production of lactic acid. The transformed E. coli of the invention are prepared by deleting the genes that encode competing pathways followed by a growth-based selection for mutants with improved performance. These transformed E. coli are useful for providing an increased supply of lactic acid for use in food and industrial applications.
摘要翻译： 本发明提供了用于生产乳酸的酿酒酵母大肠杆菌K011的衍生物。 本发明的转化的大肠杆菌通过删除编码竞争性途径的基因，随后是具有改进性能的突变体的基于生长的选择来制备。 这些转化的大肠杆菌可用于提供用于食品和工业应用的增加的乳酸供应。
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公开(公告)号：US20050250192A1
公开(公告)日：2005-11-10
申请号：US10793568
申请日：2004-03-04
摘要： The subject invention relates to newly isolated organisms from nature that produce L(+)-lactic acid high yield from hexose and pentose sugars found in biomass. Organisms and processes or methods for the production of lactic acid and other industrially important chemicals from cellulose and hemicellulose are also provided.
摘要翻译： 本发明涉及从生物质中发现的己糖和戊糖中产生L（+） - 乳酸的高产率的来自大自然的新分离的生物。 还提供了用于从纤维素和半纤维素生产乳酸和其它工业上重要的化学物质的生物和方法或方法。
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