Process for producing nucleoside
    2.
    发明授权
    Process for producing nucleoside 有权
    生产核苷的方法

    公开(公告)号:US08653254B2

    公开(公告)日:2014-02-18

    申请号:US13260096

    申请日:2010-03-30

    IPC分类号: C07H21/00

    CPC分类号: C07H23/00 C07H19/06 C07H19/16

    摘要: There is a demand for a convenient production method of an NC type purine nucleoside.The present invention relates to a method of producing a purine nucleoside represented the formula (I′) or a salt thereof, which comprising reacting a pyrimidine nucleoside represented by the formula (I) or a salt thereof with a purine nucleobase represented by the formula B′H in the presence of a Lewis acid.

    摘要翻译: 需要一种方便的NC型嘌呤核苷的生产方法。 本发明涉及一种制备式(I')的嘌呤核苷或其盐的方法,该方法包括使由式(I)表示的嘧啶核苷或其盐与由式B表示的嘌呤核碱基反应 在路易斯酸存在下的H。

    Spiro compounds having stearoyl-CoA desaturase action
    3.
    发明授权
    Spiro compounds having stearoyl-CoA desaturase action 有权
    具有硬脂酰-CoA去饱和酶作用的螺环化合物

    公开(公告)号:US08575167B2

    公开(公告)日:2013-11-05

    申请号:US12449320

    申请日:2008-02-05

    摘要: The present invention aims to provide a novel SCD inhibitor.The present invention relate to SCD inhibitor comprising A compound represented by the formula (I) wherein R is an optionally substituted cyclic group or an optionally substituted carbamoyl group, provided that R is not an optionally substituted 7-pyrido[2,3-d]pyrimidyl group; ring A is an optionally further substituted pyridazine ring; R1, R2, R3, R4, R11, R12, R13 and R14 are each independently a hydrogen atom or a substituent, or R1 and R11 in combination, R2 and R12 in combination, R3 and R13 in combination, or R4 and R14 in combination optionally form an oxo group, or R2 and R4 in combination optionally form a bond or an alkylene cross-linkage; m and n are each independently an integer of 0 to 2; ring B is an optionally substituted ring, provided that the two atoms constituting ring B, which are adjacent to the spiro carbon atom, are not oxygen atoms at the same time, or a salt thereof, or a prodrug thereof.

    摘要翻译: 本发明旨在提供一种新型的SCD抑制剂。 本发明涉及包含由式(I)表示的化合物的SCD抑制剂,其中R是任选取代的环状基团或任选取代的氨基甲酰基,条件是R不是任选取代的7-吡啶并[2,3-d] 嘧啶基; 环A是任选进一步取代的哒嗪环; R 1,R 2,R 3,R 4,R 11,R 12,R 13和R 14各自独立地为氢原子或取代基,或R 1和R 11组合,R 2和R 12组合,R 3和R 13组合,或R 4和R 14组合 任选地形成氧代基团,或者R 2和R 4组合任选地形成键或亚烷基交联; m和n各自独立地为0〜2的整数。 环B是任选取代的环,条件是与螺环碳原子相邻的构成环B的两个原子不是同时为氧原子,或其盐或其前药。

    Combustion power tool
    4.
    发明授权
    Combustion power tool 有权
    燃烧电动工具

    公开(公告)号:US08511528B2

    公开(公告)日:2013-08-20

    申请号:US12896320

    申请日:2010-10-01

    IPC分类号: B25C1/08

    CPC分类号: B25C1/08

    摘要: A technique for improving the cooling performance of a combustion chamber in a combustion power tool is provided. The combustion power tool includes first and second combustion chambers, a partition that separates the first combustion chamber from the second combustion chamber, openings, formed in the partition and communicate the first combustion chamber with the second combustion chamber, and a drive section that moves toward a front end by combustion pressure. The combustion pressure is generated when a flow of flammable gas, which is produced by combustion of the flammable gas in the first combustion chamber propagates to the second combustion chamber through the openings, and burns flammable gas in the second combustion chamber. The combustion gas flows from the first combustion chamber to the second combustion chamber in a direction around a central axis of the second combustion chamber while flowing along an inner wall of the second combustion chamber.

    摘要翻译: 提供了一种用于提高燃烧动力工具中的燃烧室的冷却性能的技术。 燃烧动力工具包括第一和第二燃烧室,将第一燃烧室与第二燃烧室分隔开的隔板,形成在隔板中的开口,并将第一燃烧室与第二燃烧室连通;以及驱动部分, 前端由燃烧压力。 当通过第一燃烧室中的可燃性气体的燃烧产生的可燃气体的流动通过开口传播到第二燃烧室并且燃烧第二燃烧室中的可燃气体时,产生燃烧压力。 燃烧气体沿着第二燃烧室的内壁沿着第二燃烧室的中心轴线的方向从第一燃烧室流向第二燃烧室。

    METHOD FOR SYNTHESIZING NUCLEIC ACID
    5.
    发明申请
    METHOD FOR SYNTHESIZING NUCLEIC ACID 审中-公开
    合成核酸的方法

    公开(公告)号:US20120108800A1

    公开(公告)日:2012-05-03

    申请号:US13379485

    申请日:2010-06-22

    CPC分类号: C07H9/04 C07H19/16 Y02P20/55

    摘要: Provided is a new production method for the synthesis of an NC type nucleoside efficiently and conveniently in a high yield without unnecessary protecting group conversion steps. It relates to a step of producing a compound represented by the formula (II): or a salt thereof, by inverting a compound represented by the formula (I): and a method of producing a compound represented by the formula (III): or a salt thereof (wherein each symbol is as defined in the specification), which includes the step.

    摘要翻译: 提供了一种用于以高产率有效且方便地合成NC型核苷的新方法,而无需不需要的保护基转化步骤。 本发明涉及通过使由式(I)表示的化合物反转而制备由式(II)表示的化合物或其盐:和由式(III)表示的化合物的制备方法:或 其盐(其中每个符号如说明书中所定义),其包括该步骤。

    Virtual file servers with storage device
    6.
    发明授权
    Virtual file servers with storage device 有权
    具有存储设备的虚拟文件服务器

    公开(公告)号:US07970917B2

    公开(公告)日:2011-06-28

    申请号:US12687305

    申请日:2010-01-14

    IPC分类号: G06F15/16 G06F15/173

    摘要: A system renting out file servers to many companies in a data center has a security problem so that the user cannot perform operation needing manager authorization in the file servers. An OS provides execution administrative area information of an application program designated by process information which can specify the range of an accessible device to operate the server system of the customer in the administrative area information.

    摘要翻译: 向数据中心的许多公司出租文件服务器的系统存在安全问题,因此用户无法在文件服务器中执行需要管理员授权的操作。 OS提供由处理信息指定的应用程序的执行管理区域信息,该处理信息可以指定在管理区域信息中操作客户的服务器系统的可访问设备的范围。

    Combustion power tool
    7.
    发明授权
    Combustion power tool 失效
    燃烧电动工具

    公开(公告)号:US07461766B2

    公开(公告)日:2008-12-09

    申请号:US10984349

    申请日:2004-11-08

    IPC分类号: B25C1/08

    CPC分类号: B25C1/08

    摘要: It is an object of the present invention to provide a combustion power tool having a rational construction. A representative combustion power tool according to the invention may include a combustion chamber, a fuel supplier to supply fuel into the combustion chamber, an igniter disposed in the combustion chamber, a driving mechanism actuated to perform a predetermined operation by utilizing a combustion pressure generated when the fuel is burned in the combustion chamber and an actuator that operates the fuel supplier and the igniter in one operation. Based on the operation of the actuator, fuel is supplied into the combustion chamber via the fuel supplier and the igniter performs ignition in relation to the pressure of the fuel supplied into the combustion chamber changes. According to the invention, because the fuel supplying and ignition can be done by the actuator in one operation, ignition can be performed in constant timing after fuel is supplied via the fuel supplying means. As a result, the operability can be improved and stable combustion can be always achieved.

    摘要翻译: 本发明的目的是提供具有合理结构的燃烧动力工具。 根据本发明的代表性燃烧动力工具可以包括燃烧室,用于向燃烧室供应燃料的燃料供应器,设置在燃烧室中的点火器,通过利用当燃烧室中产生的燃烧压力而致动以执行预定操作的驱动机构 燃料在燃烧室中燃烧,并且在一个操作中操作燃料供应器和点火器的致动器。 基于致动器的操作,燃料经由燃料供应器供应到燃烧室中,并且点火器相对于供应到燃烧室的燃料的压力进行点火改变。 根据本发明,由于在一次操作中可以由致动器进行燃料供给和点火,所以可以在通过燃料供给装置供给燃料之后以恒定的时刻进行点火。 结果,可以提高可操作性,并且可以始终实现稳定的燃烧。

    Storage system for managing data with predetermined retention periods
    8.
    发明申请
    Storage system for managing data with predetermined retention periods 审中-公开
    用于以预定保留期管理数据的存储系统

    公开(公告)号:US20050177591A1

    公开(公告)日:2005-08-11

    申请号:US10852223

    申请日:2004-05-25

    摘要: Time information from a time server may be incorrect because of human mistakes or cracking. This may cause time errors of one year or more and then data recorded in a storage device might be altered or deleted before their retention periods expire, which would lead to serious troubles. Provided is a storage system including: a plurality of time servers that distribute time information; a time server management device that obtains the time information from the plurality of time servers and selects a most reliable time server; and a file management device that make a decision as to whether a retention period of the data recorded in the storage device ends after the time obtained from the most reliable time server and prohibits alteration and deletion of the data depending on the decision.

    摘要翻译: 时间服务器的时间信息可能由于人为错误或破裂而不正确。 这可能导致一年或更长时间的错误,然后记录在存储设备中的数据可能在保留期到期之前被更改或删除,这将导致严重的问题。 提供一种存储系统,包括:分发时间信息的多个时间服务器; 时间服务器管理装置,其从多个时间服务器获取时间信息,并选择最可靠的时间服务器; 以及文件管理装置,作出关于存储装置中记录的数据的保留期间是否在从最可靠的时间服务器获得的时间之后结束的文件管理装置,并且根据该决定禁止更改和删除数据。

    Combustion power tool
    9.
    发明申请
    Combustion power tool 失效
    燃烧电动工具

    公开(公告)号:US20050098123A1

    公开(公告)日:2005-05-12

    申请号:US10984349

    申请日:2004-11-08

    IPC分类号: B25C1/08 F02B71/00

    CPC分类号: B25C1/08

    摘要: It is an object of the present invention to provide a combustion power tool having a rational construction. A representative combustion power tool according to the invention may include a combustion chamber, a fuel supplier to supply fuel into the combustion chamber, an igniter disposed in the combustion chamber, a driving mechanism actuated to perform a predetermined operation by utilizing a combustion pressure generated when the fuel is burned in the combustion chamber and an actuator that operates the fuel supplier and the igniter in one operation. Based on the operation of the actuator, fuel is supplied into the combustion chamber via the fuel supplier and the igniter performs ignition in relation to the pressure of the fuel supplied into the combustion chamber changes. According to the invention, because the fuel supplying and ignition can be done by the actuator in one operation, ignition can be performed in constant timing after fuel is supplied via the fuel supplying means. As a result, the operability can be improved and stable combustion can be always achieved.

    摘要翻译: 本发明的目的是提供具有合理结构的燃烧动力工具。 根据本发明的代表性燃烧动力工具可以包括燃烧室,用于向燃烧室供应燃料的燃料供应器,设置在燃烧室中的点火器,通过利用当燃烧室中产生的燃烧压力而致动以执行预定操作的驱动机构 燃料在燃烧室中燃烧,并且在一个操作中操作燃料供应器和点火器的致动器。 基于致动器的操作,燃料经由燃料供应器供应到燃烧室中,并且点火器相对于供应到燃烧室的燃料的压力进行点火改变。 根据本发明,由于在一次操作中可以由致动器进行燃料供给和点火,所以可以在通过燃料供给装置供给燃料之后以恒定的时刻进行点火。 结果,可以提高可操作性,并且可以始终实现稳定的燃烧。