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公开(公告)号：US08734827B2
公开(公告)日：2014-05-27
申请号：US11742040
申请日：2007-04-30
IPC分类号： A61F2/44 , C12N5/0775 , A61F2/28 , A61K38/39
CPC分类号： A61F2/442 , A61F2/3094 , A61F2002/2817 , A61F2002/30006 , A61F2002/30016 , A61F2002/30153 , A61F2002/30677 , A61F2002/30971 , A61F2002/4445 , A61F2002/445 , A61F2230/0019 , A61F2250/0015 , A61F2250/0018 , A61F2250/0019 , A61F2310/00365 , A61K2035/128 , A61L27/3633 , A61L27/3834 , A61L27/3852 , A61L27/3856 , A61L2430/38 , C12N5/0663 , C12N2533/54
摘要： A bioengineered IVD for disc replacement has been developed that has mechanical and structural support characteristics similar to those of native IVD. Extracellular matrix (ECM) provides support to living cell components and interacts with the living cellular components during the fabrication process without introducing toxicity. The composition can be produced from both natural or synthetic source but preferably natural and induced to self-assemble or reconstitute into its solid form under conditions that are mild enough to support cellular survival and growth. The cells induce a volume change of the structures, leading to changes in dimension, ECM density, cell density, mechanical property and stability, etc. The extent of the change in volume of the composition can be precisely controlled by factors such as the density of the ECM, the density of the living cells, the timing for interaction and the serum concentration. Increased structural support is provided by crosslinking.
摘要翻译： 已经开发了用于盘替代的生物工程IVD，其具有与天然IVD相似的机械和结构支持特征。 细胞外基质（ECM）在制造过程中提供对活细胞组分的支持和与活细胞组分的相互作用，而不引入毒性。 组合物可以天然或合成来源产生，但优选天然产生，并且在足够温和以支持细胞存活和生长的条件下诱导自组装或重组成其固体形式。 这些细胞诱导结构的体积变化，导致尺寸变化，ECM密度，细胞密度，机械性能和稳定性等。组合物体积变化的程度可以由诸如密度 ECM，活细胞的密度，相互作用的时间和血清浓度。 通过交联提供增加的结构支撑。
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公开(公告)号：US20120148632A1
公开(公告)日：2012-06-14
申请号：US13159837
申请日：2011-06-14
申请人： Barbara Pui Chan , Hiu Wa Cheng , Daniel Tsz Kit Chik , Kenneth Man Chee Cheung , Keith Dip Kei Luk
发明人： Barbara Pui Chan , Hiu Wa Cheng , Daniel Tsz Kit Chik , Kenneth Man Chee Cheung , Keith Dip Kei Luk
摘要： A simple, highly flexible and scalable platform for making functional complex tissues with heterogeneity and irregularity is provided. The method includes combining undifferentiated cells, such as pluripotent or multipotent stem cells, with a biomaterial to make multiple undifferentiated or naïve subunits, exposing the undifferentiated or naïve subunits to different cell culture environments for induction of differentiation towards different lineages as required by that complex tissue, and combining the then functional subunits with or without the undifferentiated subunits. The differentiated subunits thus combined can be cultured under biological, chemical, and/or physical culture conditions suitable to fine-tune the structural and functional properties of the bioengineered complex tissue to form a bioengineered tissue graft that mimics the structural and functional characteristics of native complex tissue. The bioengineered tissue graft can then used to replace dysfunctional tissue.
摘要翻译： 提供了一个简单，高度灵活和可扩展的平台，用于制作具有异质性和不规则性的功能性复合组织。 该方法包括将未分化细胞如多能干细胞或多潜能干细胞与生物材料组合以制备多个未分化或未初始的亚基，将未分化或未初始的亚基暴露于不同的细胞培养环境，以根据该复合组织的要求诱导向不同谱系的分化 ，然后结合当时的功能亚基与或不与未分化的亚单位。 如此组合的分化亚基可以在适于微调生物工程化复合组织的结构和功能特性的生物，化学和/或物理培养条件下进行培养以形成模拟天然复合物的结构和功能特征的生物工程化组织移植物 组织。 然后生物工程组织移植物可用于替代功能障碍组织。
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公开(公告)号：US08444682B2
公开(公告)日：2013-05-21
申请号：US11853686
申请日：2007-09-11
IPC分类号： A61B17/86
CPC分类号： A61B17/7032 , A61B17/7034 , A61B2017/00867
摘要： A mechanism to connect the supporting portions of orthopaedic implants such as in the head, spine, upper limb and lower limb and thereby prevent loosening and fretting at the implant interface of an orthopaedic implant construct has been developed based on shape memory effect and super-elasticity of shape memory materials such as nickel-titanium (nitinol or NiTi) shape-memory-alloy, without the use of typical threaded fastening technique. Advantages are conferred by making the entire device, not just connecting pieces, out of shape memory alloy and having shape memory effect and super-elasticity. Heating the memory head of the device will compress the connection portion without the use of an auxiliary device (e.g. coupling member) so that the connection portion can be completely clamped down by the memory head. Further advantages are provided through the use of a two-way shape memory effect in which the memory device can be closed or tightened by heating up the ambient temperature, and re-opened by cooling down the temperature.
摘要翻译： 基于形状记忆效应和超弹性，已经开发了一种机构，用于连接诸如头部，脊柱，上肢和下肢之类的矫形植入物的支撑部分，从而防止在矫形植入物构造的植入物界面松动和微动。 的形状记忆材料如镍钛（镍钛诺或NiTi）形状记忆合金，而不使用典型的螺纹紧固技术。 通过将整个装置，不仅仅是连接件，形状记忆合金，并具有形状记忆效应和超弹性来赋予优点。 加热设备的存储头将不会使用辅助设备（例如，耦合构件）来压缩连接部分，使得连接部分可以被存储头完全夹紧。 通过使用双向形状记忆效应来提供进一步的优点，其中可以通过加热环境温度来关闭或紧固存储器件，并且通过冷却温度来重新打开。
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4.发明申请公开(公告)号：US20120163206A1
公开(公告)日：2012-06-28
申请号：US13216201
申请日：2011-08-23
CPC分类号： H04L67/12 , G01S3/023 , G01S5/0009 , G01S5/0284 , G01S5/0294 , G01S11/06 , G06Q10/063 , G06Q50/30 , H04B17/318 , H04B17/373 , H04L63/0428 , H04L67/22 , H04L67/303 , H04W4/02 , H04W4/021 , H04W4/023 , H04W4/025 , H04W4/38 , H04W4/80 , H04W12/02 , H04W64/00
摘要： Multiple packets are received that were transmitted by multiple mobile electronic device sensors located in a predefined area. The packets each include data detected by the sensors of multiple mobile electronic devices. At least a portion of the collected data is stored including multiple unique device identifiers that belong to multiple mobile electronic devices. Responsive to determining that at least two of the unique device identifiers are sequential, a set of values based on the at least two unique devices identifiers are associated as belonging to a same one of the mobile electronic devices.
摘要翻译： 接收到由位于预定区域中的多个移动电子设备传感器发送的多个分组。 这些分组各自包括由多个移动电子设备的传感器检测到的数据。 存储收集的数据的至少一部分，包括属于多个移动电子设备的多个唯一设备标识符。 响应于确定所述唯一设备标识符中的至少两个是顺序的，基于所述至少两个唯一设备标识符的一组值被关联为属于所述移动电子设备中的相同的一个。
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公开(公告)号：US20080053575A1
公开(公告)日：2008-03-06
申请号：US11927816
申请日：2007-10-30
申请人： Kenneth Man Chee Cheung , Kelvin Yeung , William Lu , Chi Chung
发明人： Kenneth Man Chee Cheung , Kelvin Yeung , William Lu , Chi Chung
IPC分类号： C22C30/00
CPC分类号： A61B17/866 , A61B17/72 , A61B17/80 , A61B17/842 , A61B2017/00867 , C22C19/03 , C22C30/00 , C22F1/006 , Y10T428/12
摘要： The present invention relates generally to a shape memory and/or super-elastic material, such as a nickel titanium alloy. Additionally or alternatively, the present invention relates to a super-elastic or pseudo-elastic material that has an initial transition temperature Af above a body temperature. The shape memory material can have a super-elasticity or pseudo-elasticity property at a temperature below the initial transition temperature Af of the material. For example, the shape memory material can have its workable temperature for producing super-elasticity or pseudo-elasticity of about 0° C. to 15° C. below the initial transition temperature Af. The shape memory material can be malleable at a room temperature, and become super-elastic or pseudo-elastic at a body temperature. In addition, the present invention relates to a method of making a shape memory or a super-elastic material. The treatment protocols can include but not limited to thermo-mechanical, thermo-mechanical, radiation, and ternary alloying treatments.
摘要翻译： 本发明一般涉及形状记忆和/或超弹性材料，例如镍钛合金。 另外或替代地，本发明涉及超弹性或假弹性材料，其具有高于体温的初始转变温度A 。 形状记忆材料可以在低于材料的初始转变温度A 的温度下具有超弹性或假弹性性质。 例如，形状记忆材料可具有用于产生低于初始转变温度A
的约0℃至15℃的超弹性或假弹性的可工作温度。 形状记忆材料可以在室温下延展，并且在体温下变得超弹性或假弹性。 此外，本发明涉及一种制作形状记忆或超弹性材料的方法。 处理方案可以包括但不限于热机械，热机械，辐射和三元合金化处理。 -
公开(公告)号：US11786636B2
公开(公告)日：2023-10-17
申请号：US13159837
申请日：2011-06-14
申请人： Barbara Pui Chan , Hiu Wa Cheng , Daniel Tsz Kit Chik , Kenneth Man Chee Cheung , Keith Dip Kei Luk
发明人： Barbara Pui Chan , Hiu Wa Cheng , Daniel Tsz Kit Chik , Kenneth Man Chee Cheung , Keith Dip Kei Luk
IPC分类号： C12N5/00 , C12N5/02 , A61K45/00 , A61L27/38 , C12N5/071 , A61K35/51 , C12N5/077 , A61K35/545 , A61K35/28 , A01K67/00
CPC分类号： A61L27/3891 , A61K35/28 , A61K35/51 , A61K35/545 , A61L27/3834 , C12N5/0012 , C12N5/0654 , C12N5/0655 , C12N5/0697 , C12N2502/1311 , C12N2502/1317 , C12N2502/1358 , C12N2527/00 , C12N2533/54
摘要： A simple, highly flexible and scalable platform for making functional complex tissues with heterogeneity and irregularity is provided. The method includes combining undifferentiated cells, such as pluripotent or multipotent stem cells, with a biomaterial to make multiple undifferentiated or naïve subunits, exposing the undifferentiated or naïve subunits to different cell culture environments for induction of differentiation towards different lineages as required by that complex tissue, and combining the then functional subunits with or without the undifferentiated subunits. The differentiated subunits thus combined can be cultured under biological, chemical, and/or physical culture conditions suitable to fine-tune the structural and functional properties of the bioengineered complex tissue to form a bioengineered tissue graft that mimics the structural and functional characteristics of native complex tissue. The bioengineered tissue graft can then used to replace dysfunctional tissue.
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7.发明授权公开(公告)号：US08699370B2
公开(公告)日：2014-04-15
申请号：US13216201
申请日：2011-08-23
IPC分类号： H04L12/28
CPC分类号： H04L67/12 , G01S3/023 , G01S5/0009 , G01S5/0284 , G01S5/0294 , G01S11/06 , G06Q10/063 , G06Q50/30 , H04B17/318 , H04B17/373 , H04L63/0428 , H04L67/22 , H04L67/303 , H04W4/02 , H04W4/021 , H04W4/023 , H04W4/025 , H04W4/38 , H04W4/80 , H04W12/02 , H04W64/00
摘要： Multiple packets are received that were transmitted by multiple mobile electronic device sensors located in a predefined area. The packets each include data detected by the sensors of multiple mobile electronic devices. At least a portion of the collected data is stored including multiple unique device identifiers that belong to multiple mobile electronic devices. Responsive to determining that at least two of the unique device identifiers are sequential, a set of values based on the at least two unique devices identifiers are associated as belonging to a same one of the mobile electronic devices.
摘要翻译： 接收到由位于预定区域中的多个移动电子设备传感器发送的多个分组。 这些分组各自包括由多个移动电子设备的传感器检测到的数据。 存储收集的数据的至少一部分，包括属于多个移动电子设备的多个唯一设备标识符。 响应于确定所述唯一设备标识符中的至少两个是顺序的，基于所述至少两个唯一设备标识符的一组值被关联为属于所述移动电子设备中的相同的一个。
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公开(公告)号：US07786998B2
公开(公告)日：2010-08-31
申请号：US10987397
申请日：2004-11-12
申请人： Henry Law , Kenneth Man
发明人： Henry Law , Kenneth Man
IPC分类号： G09G5/39
CPC分类号： H04N5/915
摘要： The present disclosure discusses methods and apparatus for controlling the video playback in a video playback system. In particular, a method for controlling video playback includes receiving a flip call to display video data from a flip queue buffer. Processing of the video data is then initiated. Flip acknowledgement information is issued in response to receiving the flip call information and prior to completion of the processing of video data to be displayed from the flip queue buffer. By issuing flip acknowledgement information regardless of whether the processing of the video data has been completed, video flip calls can continue to be issued at a constant rate and other processing can continue without waiting, thus resulting in better and smoother video playback and economizing processing resources. Additionally, a decision whether or not to drop a particular video frame is made based on whether a flip queue buffer from a predetermined number of flip queue buffers is available. The disclosed apparatus includes a flip manager, such as under the control of a driver, that controls the timing of video frame flips, rather than an application controlling the timing.
摘要翻译： 本公开讨论了用于控制视频播放系统中的视频播放的方法和装置。 特别地，一种用于控制视频播放的方法包括接收翻转呼叫以从翻转队列缓冲器显示视频数据。 然后启动视频数据的处理。 响应于接收到翻转呼叫信息并在完成对要从翻转队列缓冲器显示的视频数据的处理之前发出翻转确认信息。 通过发送翻转确认信息，而不管视频数据的处理是否已经完成，视频翻转呼叫可以以恒定速率继续发布，并且其他处理可以继续而不需要等待，从而导致更好和更平滑的视频播放并节省处理资源 。 此外，基于来自预定数量的翻转队列缓冲器的翻转队列缓冲器是否可用，进行是否丢弃特定视频帧的决定。 所公开的装置包括诸如在驾驶员的控制下的翻转管理器，其控制视频帧翻转的定时，而不是控制定时的应用。
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公开(公告)号：US20060104599A1
公开(公告)日：2006-05-18
申请号：US10987397
申请日：2004-11-12
申请人： Henry Law , Kenneth Man
发明人： Henry Law , Kenneth Man
IPC分类号： H04N5/76
CPC分类号： H04N5/915
摘要： The present disclosure discusses methods and apparatus for controlling the video playback in a video playback system. In particular, a method for controlling video playback includes receiving a flip call to display video data from a flip queue buffer. Processing of the video data is then initiated. Flip acknowledgement information is issued in response to receiving the flip call information and prior to completion of the processing of video data to be displayed from the flip queue buffer. By issuing flip acknowledgement information regardless of whether the processing of the video data has been completed, video flip calls can continue to be issued at a constant rate and other processing can continue without waiting, thus resulting in better and smoother video playback and economizing processing resources. Additionally, a decision whether or not to drop a particular video frame is made based on whether a flip queue buffer from a predetermined number of flip queue buffers is available. The disclosed apparatus includes a flip manager, such as under the control of a driver, that controls the timing of video frame flips, rather than an application controlling the timing.
摘要翻译： 本公开讨论了用于控制视频播放系统中的视频播放的方法和装置。 特别地，一种用于控制视频播放的方法包括接收翻转呼叫以从翻转队列缓冲器显示视频数据。 然后启动视频数据的处理。 响应于接收到翻转呼叫信息并在完成对要从翻转队列缓冲器显示的视频数据的处理之前发出翻转确认信息。 通过发送翻转确认信息，而不管视频数据的处理是否已经完成，视频翻转呼叫可以以恒定速率继续发布，并且其他处理可以继续而不需要等待，从而导致更好和更平滑的视频播放并节省处理资源 。 此外，基于来自预定数量的翻转队列缓冲器的翻转队列缓冲器是否可用，进行是否丢弃特定视频帧的决定。 所公开的装置包括诸如在驾驶员的控制下的翻转管理器，其控制视频帧翻转的定时，而不是控制定时的应用。
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公开(公告)号：US5696408A
公开(公告)日：1997-12-09
申请号：US705728
申请日：1996-08-30
申请人： Kenneth Man
发明人： Kenneth Man
IPC分类号： B60R25/04
CPC分类号： B60R25/04
摘要： A secondary ignition switch system that connects to a conventional ignition switch system of a vehicle to provide a security function. The secondary ignition system includes a dashboard mounted double-pole-double-throw (DPDT) switch and a key operated secondary ignition switch. The DPDT switch controls the operation of the primary and secondary ignition switches. To start the engine the DPDT is set to a position to power the secondary ignition switch, such that the engine can be started by turning a secondary key. However, based on the interconnection of the ignition switches the steering column of the vehicle remains locked. Only until the operator uses the primary key to unlock the steering assembly can the car be driven. This system enables the engine of a vehicle to run including powering the accessory circuit (for heating/cooling and power accessories) to warm a vehicle in cold climates with minimized risk since the steering assembly remains locked. In addition, when the secondary key is removed from the secondary ignition switch no current flows to the primary ignition switch rendering the entire system disabled.
摘要翻译： 二次点火开关系统，其连接到常规的车辆点火开关系统以提供安全功能。 二次点火系统包括仪表板安装的双极双掷（DPDT）开关和钥匙操作的二次点火开关。 DPDT开关控制主要和次要点火开关的操作。 为了启动发动机，DPDT被设置到为二次点火开关供电的位置，使得可以通过转动辅助钥匙来启动发动机。 然而，基于点火开关的互连，车辆的转向柱保持锁定。 只有在操作员使用主键解锁转向组件之前，才能驱动汽车。 该系统使得车辆的发动机能够运行，包括为了在寒冷的气候条件下加热附件回路（用于加热/冷却和电力附件），以最小化风险，因为转向组件保持锁定。 另外，当从次级点火开关中除去次级钥匙时，没有电流流向初级点火开关，导致整个系统被禁用。
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