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公开(公告)号：USD354141S
公开(公告)日：1995-01-03
申请号：US13330
申请日：1993-09-22
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公开(公告)号：US5589335A
公开(公告)日：1996-12-31
申请号：US290001
申请日：1994-08-11
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6832 , C12Q1/6806 , C12Q1/689 , Y10S435/967
摘要： Novel reagents are provided along with methods for their use in nucleic acid hybridization assays for detecting target nucleic acids in samples. The most preferred reagent is a mixture of guanidinium thiocyanate and tetramethylammonium:Trifluoracetate and possesses many properties for facilitating hybridization between target nucleic acid and nucleic acid probes capable of binding thereto and surprisingly results in the phenomenon of superstoichiometric labeling.
摘要翻译： 提供了新的试剂以及用于检测样品中靶核酸的核酸杂交测定中使用的方法。 最优选的试剂是硫氰酸胍和四甲基铵：三氟乙酸盐的混合物，并且具有许多促进靶核酸与能够结合到其上的核酸探针之间的杂交的性质，并且令人惊讶地导致超化学计量标记的现象。
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公开(公告)号：US5759777A
公开(公告)日：1998-06-02
申请号：US469208
申请日：1995-06-06
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6832 , C12Q1/6806 , C12Q1/689 , Y10S435/967
摘要： Novel reagents are provided along with methods for their use in nucleic acid hybridization assays for detecting target nucleic acids in samples. The most preferred reagent is a mixture of guanidinium thiocyanate and tetramethylammonium:Trifluoracetate and possesses many properties for facilitating hybridization between target nucleic acid and nucleic acid probes capable of binding thereto and surprisingly results in the phenomenon of superstoichiometric labeling.
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公开(公告)号：USD354220S
公开(公告)日：1995-01-10
申请号：US13241
申请日：1993-09-22
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公开(公告)号：US5374395A
公开(公告)日：1994-12-20
申请号：US136654
申请日：1993-10-14
申请人： David Robinson , Ernest Bate , Simon Kellard , Mark Watson , Donald E. Mahan , Thomas M. Shimei , Kevin R. Kearney
发明人： David Robinson , Ernest Bate , Simon Kellard , Mark Watson , Donald E. Mahan , Thomas M. Shimei , Kevin R. Kearney
CPC分类号： G01N35/025 , G01N21/253 , G01N2035/00049 , G01N2035/00316 , G01N2035/00356 , G01N2035/00752 , G01N2035/0436 , G01N2035/1025 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/114998 , Y10T436/25 , Y10T436/2575
摘要： A dependable cost-effective clinical analyzer machine provides an efficient and easy-to-use diagnostics instrument and process to accurately, rapidly and automatically test and analyze samples in test packs for an analyte. In the clinical analyzer machine, remote-controlled trams transport test packs containing loading/unloading station to a processing/testing station via a carousel and vice versa. In the processing station, a special processor with mechanically-operated rollers mixing shoes, wastegate assembly, magnets, clamp plate and a thermal sealer, process samples in test packs with various reagents to detect an analyte. The carousel holds the test packs during incubation periods and rotates the tested disposable packs past an optical reader which optically senses the presence of an analyte in the sample. Bar code readers are provided to assist in identification of the test pack, patient and sample.
摘要翻译： 可靠的具有成本效益的临床分析仪提供了一种高效且易于使用的诊断仪器和过程，用于准确，快速和自动地测试和分析分析物的测试包中的样品。 在临床分析仪器中，遥控电车将装载/卸载站的测试包通过转盘运送到加工/检测站，反之亦然。 在处理站中，具有机械操作的辊混合鞋，废气门组件，磁体，夹板和热封合器的特殊处理器，在具有各种试剂的测试包中处理样品以检测分析物。 转盘在孵育期间保持测试包，并将测试的一次性包装旋转经过光学读取器，其光学地感测样品中分析物的存在。 提供条码阅读器，以帮助识别测试包，病人和样品。
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