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18 条记录 (耗时 0.012 秒)

    Continuous blade impeller
    1.
    发明授权
    Continuous blade impeller 有权

    公开(公告)号：US11739289B2

    公开(公告)日：2023-08-29

    申请号：US16854183

    申请日：2020-04-21

    申请人： Lonza Limited

    发明人： Michael Mietzner ,  Richard Falk ,  Rajesh Beri ,  Mark Caswell

    IPC分类号： B01F27/00 ,  C12M1/06 ,  B01F27/191 ,  B01F27/1125 ,  B01F101/44

    CPC分类号： C12M27/02 ,  B01F27/1125 ,  B01F27/191 ,  B01F2101/44

    摘要： An impeller is usable in a variable diameter bioreactor having multiple vessel sections of successively increasing or decreasing volume. The impeller includes an impeller blade extending along an impeller blade axis between first and second axial ends and having opposed impeller blade faces, an impeller blade leading edge, and an impeller blade trailing edge. Each of the leading and trailing edges defines a helix or spiral between the axial ends of the impeller blade. In certain arrangements, the impeller blade is one of at least two impeller blades joined together along an impeller shaft extending axially along the impeller blade axis mentioned, and the helix or spiral has a pitch approximately equal to one half of a length between the first and second axial ends.

    Dynamically controlling an automated system
    3.
    发明授权
    Dynamically controlling an automated system 有权

    公开(公告)号：US10928407B2

    公开(公告)日：2021-02-23

    申请号：US16939121

    申请日：2020-07-27

    申请人： LONZA LIMITED

    发明人： Dale Webster ,  Evan Carpenter

    IPC分类号： G01N35/00 ,  B25J9/00 ,  B25J9/16 ,  B25J21/00

    摘要： Systems and methods for dynamic automation are provided. An automation module may receive at least one map template that is selectable by a user. Based on the map template, the automation module may dynamically generate a robot deck layout map and/or procedure and also generate a series of robotic commands for a robot. The robotic commands may then be passed to the robot to carry out the automation. Accordingly, the automation may be entirely dynamic, without the need for a user to pre-program or pre-assemble all of the robotic commands prior to the automation. The automation module may thus be able to build, in real-time and/or on the fly, the robotic commands based only on the at least one map template that was selected by the user.

    Continuous Blade Impeller
    4.
    发明申请
    Continuous Blade Impeller 审中-公开

    公开(公告)号：US20200332241A1

    公开(公告)日：2020-10-22

    申请号：US16854183

    申请日：2020-04-21

    申请人： Lonza Limited

    发明人： Michael MIETZNER ,  Richard FALK ,  Rajesh BERI ,  Mark CASWELL

    IPC分类号： C12M1/06 ,  B01F7/00

    摘要： An impeller is usable in a variable diameter bioreactor having multiple vessel sections of successively increasing or decreasing volume. The impeller includes an impeller blade extending along an impeller blade axis between first and second axial ends and having opposed impeller blade faces, an impeller blade leading edge, and an impeller blade trailing edge. Each of the leading and trailing edges defines a helix or spiral between the axial ends of the impeller blade. In certain arrangements, the impeller blade is one of at least two impeller blades joined together along an impeller shaft extending axially along the impeller blade axis mentioned, and the helix or spiral has a pitch approximately equal to one half of a length between the first and second axial ends.

    Automated Batch Data Analysis
    5.
    发明申请
    Automated Batch Data Analysis 审中-公开

    公开(公告)号：US20180267516A1

    公开(公告)日：2018-09-20

    申请号：US15923799

    申请日：2018-03-16

    申请人： Lonza Limited

    发明人： Leslie FISTER ,  Michael GOETTER

    IPC分类号： G05B19/418

    CPC分类号： G05B19/4188 ,  G05B2219/31372 ,  Y02P90/02 ,  Y02P90/10 ,  Y02P90/18 ,  Y02P90/20

    摘要： A system for automated batch data analysis is provided. The system for automated batch data analysis includes, for example, at least one system component and a database. The system also includes at least one computing device for executing stored programmable instructions to: acquire data associated with the system component, determine which data from the received data are identified for extraction based at least in part on a tag, and extract the tagged data based on the determination.

    System and Method for Regulating Cell Culture Based Production of Biologics
    7.
    发明申请
    System and Method for Regulating Cell Culture Based Production of Biologics 审中-公开

    公开(公告)号：US20170107476A1

    公开(公告)日：2017-04-20

    申请号：US15294152

    申请日：2016-10-14

    申请人： Lonza Limited

    发明人： Rex POLLEY ,  Matthew SARCOPSKI ,  Robert HORTON ,  Thomas ELLIS ,  Paul PEASE ,  John CHAPIN

    IPC分类号： C12M1/36 ,  G01N30/86 ,  C12Q3/00

    摘要： The disclosure is directed to a system and method for control of at least one bioreactor, other cell cultivation-related equipment, and systems containing any combination of these in a plant. For example, a Plant-Wide Control System (PWCS) or a Process Control System (PCS) may be divided into three main components: hardware (including operating systems, such as a controller communicating with one or more servers of a network associated with the PWCS, (2) software (such as a control module) for performing control, and (3) one or more instrument control loops, which may be used by the software to maintain certain process values. Moreover, a Height Equivalent of a Theoretical Plate (HETP) value and an asymmetry factor may be determined based on real-time analysis on a chromatography column, using PWCS components.

    Dynamically controlling an automated system
    9.
    发明授权
    Dynamically controlling an automated system 有权

    公开(公告)号：US10768190B2

    公开(公告)日：2020-09-08

    申请号：US15878930

    申请日：2018-01-24

    申请人： Lonza Limited

    发明人： Dale Webster ,  Evan Carpenter

    IPC分类号： B25J21/00 ,  G01N35/00 ,  B25J9/00 ,  B25J9/16

    摘要： Systems and methods for dynamic automation are provided. An automation module, for example, receives at least one map template that is selectable by a user. Based on the map template, the automation module dynamically generates a robot deck layout map and/or procedure and also generates a series of robotic commands for a robot. The robotic commands are then passed to the robot to carry out the automation. Accordingly, the automation is entirely dynamic, without the need for a user to pre-program or pre-assemble all of the robotic commands prior to the automation. The automation module is thus able to build, in real-time and/or on the fly, the robotic commands based only on the at least one map template that was selected by the user.

    SYSTEM AND METHOD FOR REGULATING CELL CULTURE BASED PRODUCTION OF BIOLOGICS
    10.
    发明申请
    SYSTEM AND METHOD FOR REGULATING CELL CULTURE BASED PRODUCTION OF BIOLOGICS 审中-公开

    公开(公告)号：US20200157487A1

    公开(公告)日：2020-05-21

    申请号：US16749186

    申请日：2020-01-22

    申请人： Lonza Limited

    发明人： Rex POLLEY ,  Matthew Sarcopski ,  Robert Horton ,  Thomas Ellis ,  Paul Pease ,  John Chapin

    IPC分类号： C12M1/36 ,  G01N30/86 ,  C12Q3/00

    摘要： The disclosure is directed to a system and method for control of at least one bioreactor, other cell cultivation-related equipment, and systems containing any combination of these in a plant. For example, a Plant-Wide Control System (PWCS) or a Process Control System (PCS) may be divided into three main components: hardware (including operating systems, such as a controller communicating with one or more servers of a network associated with the PWCS, (2) software (such as a control module) for performing control, and (3) one or more instrument control loops, which may be used by the software to maintain certain process values. Moreover, a Height Equivalent of a Theoretical Plate (HETP) value and an asymmetry factor may be determined based on real-time analysis on a chromatography column, using PWCS components.