公开(公告)号：US09003433B2

公开(公告)日：2015-04-07

申请号：US13356454

申请日：2012-01-23

申请人： Shuang Liang ,  Xiao Xing Liang ,  Xin Peng Liu ,  Chang Hua Sun ,  Xi Ning Wang ,  Liang Xue ,  Yu Chen Zhou

发明人： Shuang Liang ,  Xiao Xing Liang ,  Xin Peng Liu ,  Chang Hua Sun ,  Xi Ning Wang ,  Liang Xue ,  Yu Chen Zhou

IPC分类号： G06F9/54 ,  G06F9/44 ,  G06Q10/06

CPC分类号： G06F8/38 ,  G06Q10/067

摘要： Business application logic corresponding to a business is generated according to requirements of the business. The business application logic includes Web services and Widgets. The Widgets in the business application logic are mashed up to create a Widget mashup application. An adaptation relationship is established between the Web services and the Widgets in the Widget mashup application. An executable business process is generated for the business based on the business application logic and the adaptation relationship. An executable mashup Widget application is generated based on the Widget mashup application and the adaptation relationship.

摘要翻译： 根据业务要求生成与业务相对应的业务应用逻辑。 业务应用程序逻辑包括Web服务和小部件。 业务应用程序逻辑中的窗口小部件被混合以创建一个Widget mashup应用程序。 在Web服务和Widget mashup应用程序中的Widget之间建立适应关系。 基于业务应用逻辑和适应关系为业务生成可执行的业务流程。 基于Widget mashup应用程序和适配关系生成可执行的mashup Widget应用程序。

公开(公告)号：US08788566B2

公开(公告)日：2014-07-22

申请号：US12275435

申请日：2008-11-21

申请人： Xin Peng Liu ,  Xi Ning Wang ,  Liang Xue ,  Ke Xin Zhou ,  Yu Chen Zhou

发明人： Xin Peng Liu ,  Xi Ning Wang ,  Liang Xue ,  Ke Xin Zhou ,  Yu Chen Zhou

IPC分类号： G06F15/16

CPC分类号： H04L41/0893 ,  G06F21/62 ,  H04L41/5045

摘要： A method for enforcing context model based Service-Oriented Architecture (SOA) policies is provided, which includes: gathering instance documents related to policy enforcement according to a business requirement; generating an instantiated context model using the gathered instance documents; generating a policy set to be enforced according to the gathered instance documents; determining an enforcement sequence of policies in the policy set; and applying the policies to the instantiated context model according to the enforcement sequence. The method for enforcing context model based SOA policies may flexibly gather the instance documents according to scenarios and purposes of the policy enforcement to define the policy scope, such as project, application, service, etc., and may be applied to various types of the SOA policies. In addition, a policy engine for enforcing context model based SOA policies is provided.

摘要翻译： 提供了一种执行基于上下文模型的面向服务架构（SOA）策略的方法，其中包括：根据业务需求收集与策略实施相关的实例文档; 使用收集的实例文档生成实例化的上下文模型; 生成根据收集的实例文档执行的策略集; 确定政策集中的政策执行顺序; 并根据执行顺序将策略应用于实例化的上下文模型。 实施基于上下文模型的SOA策略的方法可以根据策略执行的场景和目的灵活收集实例文档，以定义策略范围，如项目，应用程序，服务等，并且可以应用于各种类型的 SOA策略。 此外，还提供了一种用于实施基于上下文模型的SOA策略的策略引擎。

公开(公告)号：US20090138940A1

公开(公告)日：2009-05-28

申请号：US12275435

申请日：2008-11-21

申请人： Xin Ping Liu ,  Xi Ning Wang ,  Liang Xue ,  Ke Xin Zhou ,  Yu Chen Zhou

发明人： Xin Ping Liu ,  Xi Ning Wang ,  Liang Xue ,  Ke Xin Zhou ,  Yu Chen Zhou

IPC分类号： H04L9/00

CPC分类号： H04L41/0893 ,  G06F21/62 ,  H04L41/5045

摘要： A method for enforcing context model based Service-Oriented Architecture (SOA) policies is provided, which includes: gathering instance documents related to policy enforcement according to a business requirement; generating an instantiated context model using the gathered instance documents; generating a policy set to be enforced according to the gathered instance documents; determining an enforcement sequence of policies in the policy set; and applying the policies to the instantiated context model according to the enforcement sequence. The method for enforcing context model based SOA policies may flexibly gather the instance documents according to scenarios and purposes of the policy enforcement to define the policy scope, such as project, application, service, etc., and may be applied to various types of the SOA policies. In addition, a policy engine for enforcing context model based SOA policies is provided.

摘要翻译： 提供了一种执行基于上下文模型的面向服务架构（SOA）策略的方法，其中包括：根据业务需求收集与策略实施相关的实例文档; 使用收集的实例文档生成实例化的上下文模型; 生成根据收集的实例文档执行的策略集; 确定政策集中的政策执行顺序; 并根据执行顺序将策略应用于实例化的上下文模型。 实施基于上下文模型的SOA策略的方法可以根据策略执行的场景和目的灵活地收集实例文档，以定义策略范围，如项目，应用程序，服务等，并且可以应用于各种类型的 SOA策略。 此外，还提供了一种用于实施基于上下文模型的SOA策略的策略引擎。

公开(公告)号：US10223650B2

公开(公告)日：2019-03-05

申请号：US12277934

申请日：2008-11-25

申请人： Xin Peng Liu ,  Xi Ning Wang ,  Liang Xue ,  Ke Xin Zhou ,  Yu Chen Zhou

发明人： Xin Peng Liu ,  Xi Ning Wang ,  Liang Xue ,  Ke Xin Zhou ,  Yu Chen Zhou

IPC分类号： G06F17/30 ,  G06Q10/06 ,  G06F9/448

摘要： A method for enforcing a number of context model based policies with forward chaining comprising applying a policy set including a plurality of policies to an instantiated context model which includes a set of referenced instance documents in XML format, determining whether the instantiated context model should be updated, if the instantiated context model should be updated, executing an updating operation, re-generating a new instantiated context model according to the updated instance documents and the instantiated context model, and applying the policy set to the new instantiated context model, and wherein the policies include a condition part and an action part.

公开(公告)号：US20160024079A1

公开(公告)日：2016-01-28

申请号：US14774430

申请日：2014-03-13

申请人： Christopher Michael ADAMS ,  Charles BABU ,  Michael Paul CAPPARELLI ,  Jian DING ,  Takeru EHARA ,  Keith JENDZA ,  Nan JI ,  Rajeshri Ganesh KARKI ,  Toshio KAWANAMI ,  Liang XUE ,  Nello MAINOLFI ,  James J. POWERS ,  Michael H. SERRANO-WU ,  Chun ZHANG

发明人： Christopher Michael ADAMS ,  Charles BABU ,  Michael Paul CAPPARELLI ,  Jian DING ,  Takeru EHARA ,  Keith JENDZA ,  Nan JI ,  Rajeshri Ganesh KARKI ,  Toshio KAWANAMI ,  Liang XUE ,  Nello MAINOLFI ,  James J. POWERS ,  Michael H. SERRANO-WU ,  Chun ZHANG

IPC分类号： C07D471/04

CPC分类号： C07D471/04

摘要： The present invention provides a compound of formula (I): wherein X is N or CH, Y is NH, O or S, methods for manufacturing these compounds, and their uses as Factor B inhibitors for the treatment of conditions and diseases associated with complement alternative pathway activation such as age-related macular degeneration, diabetic retinopathy and related ophthalmic diseases. The present invention further provides pharmaceutical compositions and combinations of pharmacologically active agents.

摘要翻译： 本发明提供了式（I）化合物：其中X为N或CH，Y为NH，O或S，制备这些化合物的方法及其作为因子B抑制剂用于治疗与补体相关的病症和疾病的用途 替代途径激活如年龄相关性黄斑变性，糖尿病性视网膜病变和相关眼科疾病。 本发明还提供药物组合物和药理活性剂的组合。

公开(公告)号：US09056874B2

公开(公告)日：2015-06-16

申请号：US13826725

申请日：2013-03-14

申请人： Christopher Michael Adams ,  Charles Babu ,  Michael Paul Capparelli ,  Jian Ding ,  Takeru Ehara ,  Keith Jendza ,  Nan Ji ,  Rajeshri Ganesh Karki ,  Toshio Kawanami ,  Liang Xue ,  Nello Mainolfi ,  James J. Powers ,  Michael H. Serrano-Wu ,  Chun Zhang

发明人： Christopher Michael Adams ,  Charles Babu ,  Michael Paul Capparelli ,  Jian Ding ,  Takeru Ehara ,  Keith Jendza ,  Nan Ji ,  Rajeshri Ganesh Karki ,  Toshio Kawanami ,  Liang Xue ,  Nello Mainolfi ,  James J. Powers ,  Michael H. Serrano-Wu ,  Chun Zhang

IPC分类号： C07D403/06 ,  C07D403/04 ,  C07D403/08 ,  C07D403/14 ,  C07D401/14 ,  C07D413/14 ,  C07D487/04 ,  C07D491/048 ,  A61K31/4184 ,  C07D413/06 ,  A61K31/423 ,  A61K31/4439 ,  A61K45/06

CPC分类号： A61K31/4184 ,  A61K31/423 ,  A61K31/4245 ,  A61K31/4439 ,  A61K45/06 ,  C07D401/14 ,  C07D403/04 ,  C07D403/06 ,  C07D403/08 ,  C07D403/14 ,  C07D413/06 ,  C07D413/14 ,  C07D487/04 ,  C07D491/048

摘要： The present invention provides a compound of formula I: a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

公开(公告)号：US20120322813A1

公开(公告)日：2012-12-20

申请号：US13163662

申请日：2011-06-17

申请人： Timothy N. Linnet ,  Stan W. Linnet ,  William K. Chan ,  Liang Xue

发明人： Timothy N. Linnet ,  Stan W. Linnet ,  William K. Chan ,  Liang Xue

IPC分类号： A61K31/519 ,  A61P25/30

CPC分类号： A61K31/519

摘要： The teachings provided herein generally relate to compositions comprising a rutaecarpine derivative that activates CYP1A2 through enzyme induction. The compound can be used for treating caffeine toxicity, in some embodiments. Caffeine is just one example of a substrate that can be removed using the derivatives taught herein, and other examples, including theophylline, are provided herein.

摘要翻译： 本文提供的教导通常涉及包含通过酶诱导活化CYP1A2的芦荟鱼衍生物的组合物。 在一些实施方案中，该化合物可用于治疗咖啡因毒性。 咖啡因仅是可以使用本文教导的衍生物除去的底物的一个实例，并且本文提供了其它实例，包括茶碱。

公开(公告)号：US20120198481A1

公开(公告)日：2012-08-02

申请号：US13356454

申请日：2012-01-23

申请人： Shuang Liang ,  Xiao Xing Liang ,  Xin Peng Liu ,  Chang Hua Sun ,  Xi Ning Wang ,  Liang Xue ,  Yu Chen Zhou

发明人： Shuang Liang ,  Xiao Xing Liang ,  Xin Peng Liu ,  Chang Hua Sun ,  Xi Ning Wang ,  Liang Xue ,  Yu Chen Zhou

IPC分类号： G06F9/46

CPC分类号： G06F8/38 ,  G06Q10/067

摘要： Business application logic corresponding to a business is generated according to requirements of the business. The business application logic includes Web services and Widgets. The Widgets in the business application logic are mashed up to create a Widget mashup application. An adaptation relationship is established between the Web services and the Widgets in the Widget mashup application. An executable business process is generated for the business based on the business application logic and the adaptation relationship. An executable mashup Widget application is generated based on the Widget mashup application and the adaptation relationship.

摘要翻译： 根据业务要求生成与业务相对应的业务应用逻辑。 业务应用程序逻辑包括Web服务和小部件。 业务应用程序逻辑中的窗口小部件被混合以创建一个Widget mashup应用程序。 在Web服务和Widget mashup应用程序中的Widget之间建立适应关系。 基于业务应用逻辑和适应关系为业务生成可执行的业务流程。 基于Widget mashup应用程序和适配关系生成可执行的mashup Widget应用程序。

公开(公告)号：US20090138795A1

公开(公告)日：2009-05-28

申请号：US12277934

申请日：2008-11-25

申请人： Xin Peng Liu ,  Xi Ning Wang ,  Liang Xue ,  Ke Xin Zhou ,  Yu Chen Zhou

发明人： Xin Peng Liu ,  Xi Ning Wang ,  Liang Xue ,  Ke Xin Zhou ,  Yu Chen Zhou

IPC分类号： G06F17/00

CPC分类号： G06Q10/06 ,  G06F9/448

摘要： A method for enforcing a number of context model based policies with forward chaining comprising applying a policy set including a plurality of policies to an instantiated context model which includes a set of referenced instance documents in XML format, determining whether the instantiated context model should be updated, if the instantiated context model should be updated, executing an updating operation, re-generating a new instantiated context model according to the updated instance documents and the instantiated context model, and applying the policy set to the new instantiated context model, and wherein the policies include a condition part and an action part.

摘要翻译： 一种用于执行具有前向链接的多个基于上下文模型的策略的方法，包括将包括多个策略的策略集应用于实例化上下文模型，所述实例化上下文模型包括XML格式的一组被引用的实例文档，确定是否应当更新所述实例化上下文模型 如果应该更新实例化的上下文模型，执行更新操作，根据更新的实例文档和实例化的上下文模型重新生成新的实例化上下文模型，并将策略集合应用于新的实例化上下文模型，并且其中 政策包括条件部分和行动部分。

公开(公告)号：US20080240174A1

公开(公告)日：2008-10-02

申请号：US12056454

申请日：2008-03-27

申请人： Steven R.J. Brueck ,  Liang Xue ,  Ron Kaspi

发明人： Steven R.J. Brueck ,  Liang Xue ,  Ron Kaspi

IPC分类号： H01S3/10

CPC分类号： H01S5/12 ,  B82Y20/00 ,  H01S5/041 ,  H01S5/1212 ,  H01S5/3422

摘要： Exemplary embodiments provide tunable laser devices, methods for making the laser devices and methods for tuning the laser devices. The tunable laser devices can include an optically pumped semiconductor laser heterostructure, on which a distributed-feedback (DFB) laser grating having variable grating spacings (or chirps) can be formed. The optically pumped semiconductor laser heterostructure can be an optically pumped type-II quantum well laser structure. The emission wavelength of the tunable laser devices can be tuned by changing positions of the region illuminated by the pump laser and with respect to the chirped DFB grating. The disclosed laser devices and methods can provide tunable laser emission with a combination of narrow linewidth and high output power that can be used for remote sensing applications and/or spectroscopic applications across the entire mid infrared (IR) spectral region.

摘要翻译： 示例性实施例提供可调激光器件，用于制造激光器件的方法和用于调谐激光器件的方法。 可调激光器件可以包括光泵浦的半导体激光异质结构，其上可以形成具有可变光栅间隔（或线性调频脉冲）的分布反馈（DFB）激光光栅。 光泵浦半导体激光异质结构可以是光泵浦型II量子阱激光器结构。 可调谐激光器件的发射波长可以通过改变由泵激光器照射的区域和相对于啁啾DFB光栅的位置来调节。 所公开的激光器件和方法可以提供具有窄线宽和高输出功率的组合的可调谐激光发射，其可用于整个中红外（IR）光谱区域的遥感应用和/或光谱应用。