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    AUTOMATIC INJECTION DEVICE FOR MICROARRAY CHIP AND AUTOMATIC INJECTION HYBRIDIZATION MICROARRAY CHIP
    1.
    发明申请
    AUTOMATIC INJECTION DEVICE FOR MICROARRAY CHIP AND AUTOMATIC INJECTION HYBRIDIZATION MICROARRAY CHIP 有权
    微胶囊自动注射装置和自动注射微胶囊芯片

    公开(公告)号：US20140011703A1

    公开(公告)日：2014-01-09

    申请号：US14006488

    申请日：2012-02-10

    申请人： Jiaming Ye ,  Pinhong Wang ,  Guoqing Wang ,  Wanli Xing

    发明人： Jiaming Ye ,  Pinhong Wang ,  Guoqing Wang ,  Wanli Xing

    IPC分类号： G01N1/10

    CPC分类号： G01N1/10 ,  C12Q1/6813 ,  C40B30/04 ,  C40B40/06 ,  C40B40/10 ,  C40B40/12 ,  G01N33/543 ,  G01N33/68 ,  G01N35/1095

    摘要： An automatic injection device comprises at least an injection unit (1). The said injection unit (1) is formed by sealing a cover plate layer (3) with hydrophilic surfaces and a microfluid layer (4). The said cover plate layer (3) is provided with at least two through holes (5). he said microfluid layer (4) is provided with a hollow-out hybridization chamber (7) and at least two hollow-out microfluid channels (6). One end of each channel (6) is connected with the hybridization chamber (7), and the other end is connected with a through hole (5) of the cover plate layer (3) respectively. Taking advantage of the hydrophilicity of the cover plate, the automatic injection device makes a solution automatically enter and fill the hybridization chamber (7) and the microfluid channels (6) by the driving force of liquid surface tension. The flow uniformity of sample solution in microarray chip is achieved by the structural design of the hybridization chamber (7) and the microfluid channels (6). The automatic injection device has advantages of simple manufacture, easy operation, high hybridization efficiency, low sample cost, and automatic quantificational injection.

    摘要翻译： 自动注射装置至少包括注射单元（1）。 所述注射单元（1）通过密封具有亲水表面的盖板层（3）和微流体层（4）而形成。 所述盖板层（3）设置有至少两个通孔（5）。 他表示微流体层（4）设置有中空杂交室（7）和至少两个中空的微流体通道（6）。 每个通道（6）的一端与杂交室（7）连接，另一端分别与盖板层（3）的通孔（5）连接。 利用盖板的亲水性，自动注射装置通过液面张力的驱动力使溶液自动进入并填充杂交室（7）和微流体通道（6）。 微阵列芯片中样品溶液的流动均匀性通过杂交室（7）和微流体通道（6）的结构设计来实现。 自动注射装置制造简单，操作简便，杂交效率高，样品成本低，自动定量注射等优点。

    Interface device for bio-chip
    4.
    发明授权
    Interface device for bio-chip 有权
    生物芯片接口装置

    公开(公告)号：US09101924B2

    公开(公告)日：2015-08-11

    申请号：US14006512

    申请日：2012-02-10

    申请人： Jiaming Ye ,  Pinhong Wang ,  Guoqing Wang ,  Wanli Xing

    发明人： Jiaming Ye ,  Pinhong Wang ,  Guoqing Wang ,  Wanli Xing

    IPC分类号： G01N15/06 ,  G01N33/00 ,  G01N33/49 ,  B01L3/00

    CPC分类号： B01L3/502 ,  B01L3/502715 ,  B01L3/502784 ,  B01L2200/0689 ,  B01L2200/141 ,  B01L2300/0816 ,  B01L2300/0874 ,  B01L2300/0887 ,  B01L2400/0487

    摘要： An interface device for bio-chip at least comprises an interface unit, said interface unit consisting of instrument interface layer, fluid channel layer and sample interface layer. The instrument interface layer has at least one instrument interface. The fluid channel layer has one hollow-out fluid channel. The sample interface layer has at least one sample interface, and both ends of said fluid channel connect to the sample interface and the instrument interface respectively. The interface device separates sample solutions from the instrument interface by gas or liquid in the fluid channel, thus to avoid direct contacts between sample solutions and instrument interface which will cause pollution, and omitting cleaning processes after using instruments. With simple structure, easy operation and low cost, it applies to chemistry field, biology field and medical analysis field.

    摘要翻译： 用于生物芯片的接口装置至少包括接口单元，所述接口单元由仪器接口层，流体通道层和样品界面层组成。 仪器界面层至少有一个仪器界面。 流体通道层具有一个中空的流体通道。 样品接口层具有至少一个样品接口，并且所述流体通道的两端分别连接到样品接口和仪器接口。 界面设备通过气体或液体在流体通道中将样品溶液与仪器界面分离，从而避免样品溶液与仪器界面之间的直接接触，这将导致污染，并在使用仪器后省略清洁过程。 结构简单，操作方便，成本低，适用于化学领域，生物学领域和医学分析领域。

    INTERFACE DEVICE FOR BIO-CHIP
    6.
    发明申请
    INTERFACE DEVICE FOR BIO-CHIP 有权
    用于生物芯片的界面设备

    公开(公告)号：US20140010733A1

    公开(公告)日：2014-01-09

    申请号：US14006512

    申请日：2012-02-10

    申请人： Jiaming Ye ,  Pinhong Wang ,  Guoqing Wang ,  Wanli Xing

    发明人： Jiaming Ye ,  Pinhong Wang ,  Guoqing Wang ,  Wanli Xing

    IPC分类号： B01L3/00

    CPC分类号： B01L3/502 ,  B01L3/502715 ,  B01L3/502784 ,  B01L2200/0689 ,  B01L2200/141 ,  B01L2300/0816 ,  B01L2300/0874 ,  B01L2300/0887 ,  B01L2400/0487

    摘要： An interface device for bio-chip at least comprises an interface unit, said interface unit consisting of instrument interface layer, fluid channel layer and sample interface layer. The instrument interface layer has at least one instrument interface. The fluid channel layer has one hollow-out fluid channel. The sample interface layer has at least one sample interface, and both ends of said fluid channel connect to the sample interface and the instrument interface respectively. The interface device separates sample solutions from the instrument interface by gas or liquid in the fluid channel, thus to avoid direct contacts between sample solutions and instrument interface which will cause pollution, and omitting cleaning processes after using instruments. With simple structure, easy operation and low cost, it applies to chemistry field, biology field and medical analysis field.

    摘要翻译： 用于生物芯片的接口装置至少包括接口单元，所述接口单元由仪器接口层，流体通道层和样品界面层组成。 仪器界面层至少有一个仪器界面。 流体通道层具有一个中空的流体通道。 样品接口层具有至少一个样品接口，并且所述流体通道的两端分别连接到样品接口和仪器接口。 界面设备通过液体通道中的气体或液体将样品溶液与仪器界面分离，从而避免样品溶液与仪器界面之间的直接接触，从而造成污染，并在使用仪器后省略清洗过程。 结构简单，操作方便，成本低，适用于化学领域，生物学领域和医学分析领域。