公开(公告)号：US20060074282A1

公开(公告)日：2006-04-06

申请号：US11234866

申请日：2005-09-26

Applicant: Kevin Ward ,  R. Barbee ,  Ivo Filho ,  Roland Pittman ,  James Terner

Inventor： Kevin Ward ,  R. Barbee ,  Ivo Filho ,  Roland Pittman ,  James Terner

IPC: A61B5/00 ,  A61B6/00

CPC classification number: A61B5/14546 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/0086 ,  A61B5/1455 ,  A61B5/412 ,  A61B5/445 ,  G01N21/658

Abstract: In an emergency medicine patient, accurate measurement of change or lack thereof from non-shock, non-ischemimc, non-inflammation, non-tissue injury, non-immune dysfunction conditions is important and is provided, as practical, real-time approaches for accurately characterizing a patient's condition, using Raman spectroscopy with a high degree of accuracy, Resonance Raman spectroscopy is used to monitor tissue nitric oxide activity either in vivo or in vitro, especially as a function of its interaction with hemoglobin or other metalloproteins. Measurement times are on the order of seconds. High-accuracy measurement is achieved with Raman spectroscopy interrogation of tissue. Measurements may be non-invasive to minimally invasive. The invention may be used to monitor the effect of instituting therapies using nitric oxide or disease processes that produce nitric oxide.

Abstract translation: 在紧急医学病人中，从非休克，非缺血，非炎症，非组织损伤，非免疫功能障碍状况的准确测量变化或缺乏是非常重要的，并且作为实际的实时方法提供了实时的方法 使用拉曼光谱法准确地表征患者的状况，使用共振拉曼光谱法在体内或体外监测组织一氧化氮活性，特别是作为其与血红蛋白或其他金属蛋白相互作用的函数。 测量次数为秒数。 通过拉曼光谱询问组织实现高精度测量。 测量可能是非侵入性的微创。 本发明可用于监测使用一氧化氮或产生一氧化氮的疾病过程进行治疗的效果。

公开(公告)号：US09062189B2

公开(公告)日：2015-06-23

申请号：US12345154

申请日：2008-12-29

Applicant: Michael B. Rodgers ,  Anthony J. Dias ,  Rick Dowell Davis ,  Thomas R. Barbee ,  Shawn W. Mowry

Inventor： Michael B. Rodgers ,  Anthony J. Dias ,  Rick Dowell Davis ,  Thomas R. Barbee ,  Shawn W. Mowry

IPC: C08L9/00 ,  C08L21/00 ,  B60C1/00 ,  C08K5/01 ,  C08L7/00 ,  C08L9/06 ,  C08K3/00 ,  C08L23/22 ,  C08L23/28

CPC classification number: C08L21/00 ,  B60C1/0016 ,  C08K3/013 ,  C08K5/01 ,  C08L7/00 ,  C08L9/00 ,  C08L9/06 ,  C08L23/22 ,  C08L23/283 ,  C08L2666/06 ,  C08L2666/02

Abstract: Provided are elastomeric compositions comprising at least one elastomer and a hydrocarbon polymer additive. Preferably the hydrocarbon polymer additive comprises from 60 to 90% piperylene, from 5 to 15% cyclic components, from 5 to 20% styrenic components, up to 5% isoprene, up to 5% indenic components, and up to 10% amylene. Also provided are elastomeric compositions comprising at least one elastomer and a hydrocarbon polymer additive, wherein the hydrocarbon polymer additive has a molecular weight of from 520 to 650 g/mole and a glass transition temperature (Tg) of from 48 to 53° C. The elastomeric compositions are particularly useful in making tires and other cured rubber articles.

Abstract translation: 提供了包含至少一种弹性体和烃聚合物添加剂的弹性体组合物。 优选地，烃聚合物添加剂包含60至90％的间戊二烯，5至15％的环状组分，5至20％的苯乙烯组分，至多5％的异戊二烯，至多5％的茚成分，以及至多10％的亚甲基。 还提供了包含至少一种弹性体和烃聚合物添加剂的弹性体组合物，其中烃聚合物添加剂的分子量为520至650g / mol，玻璃化转变温度（Tg）为48至53℃。 弹性体组合物特别可用于制造轮胎和其它固化橡胶制品。

公开(公告)号：US20130184411A1

公开(公告)日：2013-07-18

申请号：US13352012

申请日：2012-01-17

Applicant: Jose M. Vargas ,  Thomas R. Barbee ,  Yuan-Ju Chen

Inventor： Jose M. Vargas ,  Thomas R. Barbee ,  Yuan-Ju Chen

IPC: B01J31/26 ,  C07C5/02 ,  C08F8/04

CPC classification number: C08F8/04 ,  B01J31/0239 ,  B01J31/0244 ,  B01J31/0268 ,  C07C5/02 ,  C07C13/28

Abstract: High strength presulfided catalyst for hydrogenating hydrocarbon resins without an in situ sulfiding step. The catalyst particles have a supported metal catalyst structure with presulfided interstitial surfaces with about 20 weight percent of a low molecular weight hydrocarbon resin, based on the weight of the porous supported metal catalyst structure, filling from 90 to 95 percent of the pore volume to improve a crush strength of the catalyst particles. The presulfided catalyst can be stored and/or shipped in an airtight container with an inert atmosphere. The catalyst particles are made by preparing the oxidized catalyst, presulfiding the catalyst, contacting the catalyst with the low molecular weight hydrocarbon resin in an inert atmosphere, sealing the catalyst in a storage/shipping container, loading the reactor with the presulfided, filled catalyst, and contacting the catalyst with an unsaturated hydrocarbon resin under hydrogenation conditions.

Abstract translation: 用于氢化烃树脂而没有原位硫化步骤的高强度预硫化催化剂。 催化剂颗粒具有支撑的金属催化剂结构，具有预硫化的间隙表面，基于多孔载体金属催化剂结构的重量，约20重量％的低分子量烃树脂，填充孔体积的90至95％以改善 催化剂颗粒的压碎强度。 预硫化的催化剂可以在具有惰性气氛的气密容器中储存和/或运输。 催化剂颗粒通过制备氧化催化剂，预硫化催化剂，在惰性气氛中使催化剂与低分子量烃树脂接触，将催化剂密封在储存/运输容器中，将反应器装载在预硫化的填充催化剂中， 并在氢化条件下使催化剂与不饱和烃树脂接触。

公开(公告)号：US20060052356A1

公开(公告)日：2006-03-09

申请号：US10952525

申请日：2004-09-29

Applicant: Kevin Ward ,  R. Barbee ,  Penny Reynolds ,  Robert Dieglemann ,  Rakesh Kukreja ,  Bruce Spiess ,  Melissa Evans ,  Eric Edwards

Inventor： Kevin Ward ,  R. Barbee ,  Penny Reynolds ,  Robert Dieglemann ,  Rakesh Kukreja ,  Bruce Spiess ,  Melissa Evans ,  Eric Edwards

IPC: A61K31/33

CPC classification number: A61K31/33

Abstract: Methods of modulating oxygen consumption in tissues are provided. In particular, the methods involve the administration of agents that transiently inhibit protein synthesis. The methods are used to treat ischemia and reperfusion-related injuries by temporarily decreasing oxygen consumption needs, and/or by inhibiting inflammation that results from reperfusion.

Abstract translation: 提供调节组织中耗氧量的方法。 特别地，该方法包括施用瞬时抑制蛋白质合成的试剂。 该方法用于通过暂时降低氧气消耗需求和/或通过抑制由再灌注引起的炎症来治疗缺血和再灌注相关的损伤。

公开(公告)号：USH2290H1

公开(公告)日：2014-04-01

申请号：US13352012

申请日：2012-01-17

Applicant: Jose M. Vargas ,  Thomas R. Barbee ,  Yuan-Ju Chen

Inventor： Jose M. Vargas ,  Thomas R. Barbee ,  Yuan-Ju Chen

IPC: B01J31/26 ,  C07C5/02 ,  C08F8/04

Abstract: High strength presulfided catalyst for hydrogenating hydrocarbon resins without an in situ sulfiding step. The catalyst particles have a supported metal catalyst structure with presulfided interstitial surfaces with about 20 weight percent of a low molecular weight hydrocarbon resin, based on the weight of the porous supported metal catalyst structure, filling from 90 to 95 percent of the pore volume to improve a crush strength of the catalyst particles. The presulfided catalyst can be stored and/or shipped in an airtight container with an inert atmosphere. The catalyst particles are made by preparing the oxidized catalyst, presulfiding the catalyst, contacting the catalyst with the low molecular weight hydrocarbon resin in an inert atmosphere, sealing the catalyst in a storage/shipping container, loading the reactor with the presulfided, filled catalyst, and contacting the catalyst with an unsaturated hydrocarbon resin under hydrogenation conditions.

公开(公告)号：US08653195B2

公开(公告)日：2014-02-18

申请号：US13822651

申请日：2011-08-17

Applicant: Edward J. Blok ,  Anthony Jay Dias ,  Robert J. Claassen, II ,  Thomas R. Barbee

Inventor： Edward J. Blok ,  Anthony Jay Dias ,  Robert J. Claassen, II ,  Thomas R. Barbee

IPC: C08F8/00 ,  C08L9/00 ,  C08L25/02 ,  C08L45/00

CPC classification number: C08L47/00 ,  B60C1/00 ,  C08L7/00 ,  C08L9/06 ,  C08L21/00 ,  C08L2666/06

Abstract: An elastomeric composition incorporating a hydrocarbon polymer modifier including piperylene, cyclic pentadiene and aromatic components, and having a softening point from 80° C. to 160° C., z-average molecular weight greater than 10,000, and at least 1 mole percent aromatic hydrogen, based on the total moles of hydrogen in the modifier. In a method, the elastomeric composition is processed with a cure package into a composition in the desired shape, which is cured to form the article. The modifier may optionally be immiscible with an elastomer in the composition and/or co-cured with the elastomer or filler in the composition. A tire or tire component may include the elastomeric composition.

Abstract translation: 一种包含烃聚合物改性剂的弹性体组合物，包括戊间二烯，环戊二烯和芳族组分，软化点为80℃至160℃，z平均分子量大于10,000，至少1摩尔％芳族氢 ，基于改性剂中氢的总摩尔数。 在一种方法中，将弹性体组合物用固化包装处理成期望形状的组合物，其被固化以形成制品。 改性剂可以任选地与组合物中的弹性体不混溶和/或在组合物中与弹性体或填料共固化。 轮胎或轮胎部件可以包括弹性体组合物。

公开(公告)号：US08735500B2

公开(公告)日：2014-05-27

申请号：US13821715

申请日：2011-08-17

Applicant: Thomas R. Barbee ,  Edward J. Blok ,  Anthony J. Dias

Inventor： Thomas R. Barbee ,  Edward J. Blok ,  Anthony J. Dias

IPC: C08L45/00 ,  C08F232/08 ,  C08F4/14

CPC classification number: C08F236/045 ,  C08F210/14 ,  C08F232/06 ,  C08L21/00 ,  C08F4/14 ,  C08F212/08 ,  C08L45/00

Abstract: A hydrocarbon polymer modifier (HPM) having high softening point and high aromaticity, is an interpolymer of (i) a piperylene component; (ii) an aromatic component; and (iii) a cyclic pentadiene component comprising a dicyclopentadiene fraction (DCPD fraction) and a dimethylcyclopentadiene fraction (MCPD fraction), wherein a weight ratio of the MCPD fraction to the DCPD fraction is from 0.8 to 20, and wherein the MCPD fraction is at least 20 wt % of the cyclic pentadiene component. In a method, the proportions of (i), (ii), (iii), and an optional amylene component are adjusted to control aromaticity, softening point and Mz of the HPM. An elastomeric composition incorporates the HPM.

Abstract translation: 具有高软化点和高芳香性的烃聚合物改性剂（HPM）是（i）戊间二烯成分的互聚物; （ii）芳族成分; 和（iii）包含二环戊二烯馏分（DCPD馏分）和二甲基环戊二烯馏分（MCPD馏分）的环状戊二烯组分，其中MCPD馏分与DCPD馏分的重量比为0.8至20，并且其中MCPD馏分为 至少20重量％的环戊二烯组分。 在一种方法中，调节（i），（ii），（iii）和任选的Amylene组分的比例以控制HPM的芳香度，软化点和Mz。 弹性体组合物包含HPM。

公开(公告)号：US20130184397A1

公开(公告)日：2013-07-18

申请号：US13822651

申请日：2011-08-17

Applicant: Edward J. Blok ,  Anthony Jay Dias ,  Robert J. Claassen, II ,  Thomas R. Barbee

Inventor： Edward J. Blok ,  Anthony Jay Dias ,  Robert J. Claassen, II ,  Thomas R. Barbee

IPC: C08L47/00

CPC classification number: C08L47/00 ,  B60C1/00 ,  C08L7/00 ,  C08L9/06 ,  C08L21/00 ,  C08L2666/06

Abstract: An elastomeric composition incorporating a hydrocarbon polymer modifier including piperylene, cyclic pentadiene and aromatic components, and having a softening point from 80° C. to 160° C., z-average molecular weight greater than 10,000, and at least 1 mole percent aromatic hydrogen, based on the total moles of hydrogen in the modifier. In a method, the elastomeric composition is processed with a cure package into a composition in the desired shape, which is cured to form the article. The modifier may optionally be immiscible with an elastomer in the composition and/or co-cured with the elastomer or filler in the composition. A tire or tire component may include the elastomeric composition.

Abstract translation: 一种包含烃聚合物改性剂的弹性体组合物，包括戊间二烯，环戊二烯和芳族组分，软化点为80℃至160℃，z平均分子量大于10,000，至少1摩尔％芳族氢 ，基于改性剂中氢的总摩尔数。 在一种方法中，将弹性体组合物用固化包装处理成期望形状的组合物，其被固化以形成制品。 改性剂可以任选地与组合物中的弹性体不混溶和/或在组合物中与弹性体或填料共固化。 轮胎或轮胎部件可以包括弹性体组合物。

公开(公告)号：US3507402A

公开(公告)日：1970-04-21

申请号：US3507402D

申请日：1967-11-02

Applicant: FLOYD R BARBEE ,  ALEXANDER RUIZ

Inventor： BARBEE FLOYD R

IPC: A47F5/13 ,  A47F7/24 ,  A47G25/06

CPC classification number: A47G25/0664 ,  A47F5/13 ,  A47F7/24

公开(公告)号：US20130211027A1

公开(公告)日：2013-08-15

申请号：US13821715

申请日：2011-08-17

Applicant: Thomas R. Barbee ,  Edward J. Blok ,  Anthony J. Dias

Inventor： Thomas R. Barbee ,  Edward J. Blok ,  Anthony J. Dias

IPC: C08F236/04

CPC classification number: C08F236/045 ,  C08F210/14 ,  C08F232/06 ,  C08L21/00 ,  C08F4/14 ,  C08F212/08 ,  C08L45/00

Abstract: A hydrocarbon polymer modifier (HPM) having high softening point and high aromaticity, is an interpolymer of (i) a piperylene component; (ii) an aromatic component; and (iii) a cyclic pentadiene component comprising a dicyclopentadiene fraction (DCPD fraction) and a dimethylcyclopentadiene fraction (MCPD fraction), wherein a weight ratio of the MCPD fraction to the DCPD fraction is from 0.8 to 20, and wherein the MCPD fraction is at least 20 wt % of the cyclic pentadiene component. In a method, the proportions of (i), (ii), (iii), and an optional amylene component are adjusted to control aromaticity, softening point and Mz of the HPM. An elastomeric composition incorporates the HPM.

Abstract translation: 具有高软化点和高芳香性的烃聚合物改性剂（HPM）是（i）戊间二烯成分的互聚物; （ii）芳族成分; 和（iii）包含二环戊二烯馏分（DCPD馏分）和二甲基环戊二烯馏分（MCPD馏分）的环状戊二烯组分，其中MCPD馏分与DCPD馏分的重量比为0.8至20，并且其中MCPD馏分为 至少20重量％的环戊二烯组分。 在一种方法中，调节（i），（ii），（iii）和任选的Amylene组分的比例以控制HPM的芳族化度，软化点和Mz。 弹性体组合物包含HPM。