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公开(公告)号：US20250126371A1
公开(公告)日：2025-04-17
申请号：US18953136
申请日：2024-11-20
Applicant: Ramot at Tel-Aviv University Ltd.
Inventor： David Mendlovic , Dan Raviv , Khen Cohen , Lior Gelberg , Mor-Avi Azulay , Menahem Koren
IPC: H04N25/47 , H04N23/56 , H04N23/74 , H04N23/84 , H04N25/707
Abstract: A dynamic vision sensor (DVS) color camera (DVS-CCam) operable to acquire a color image of a scene, the DVS-CCam including a DVS photosensor comprising DVS pixels, an illuminator operable to transmit a light pattern characterized by temporal changes in intensity and color to illuminate a scene, an optical system configured to collect and focus on the pixels of the DVS photosensor light reflected by features in the scene from the light pattern transmitted by the illuminator, and a processor configured to process DVS signals generated by the DVS pixels responsive to temporal changes in the reflected light to provide a color image of the scene.
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公开(公告)号：US20250099503A1
公开(公告)日：2025-03-27
申请号：US18729713
申请日：2023-01-25
Applicant: Ramot at Tel-Aviv University Ltd.
Inventor： Adi BARZEL , Alessio D. NAHMAD , Rashad TARADI
IPC: A61K35/17 , A61K38/00 , A61K39/00 , A61P35/00 , C07K14/705 , C07K14/715 , C07K14/725 , C07K16/10 , C07K16/32 , C12N5/0781
Abstract: The present disclosure describes a chimeric antigen receptors (CAR) that allow a cell of the B cell lineage to undergo antigen-induced activation independent of a cell of T cell lineage, compositions thereof, and method of use thereof for genetically modifying a cell of the B cell lineage or treating a subject suffering from a pathological disorder.
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公开(公告)号：US12229952B2
公开(公告)日：2025-02-18
申请号：US17614179
申请日：2020-05-27
Applicant: Ramot at Tel-Aviv University Ltd.
Inventor： Natan Tzvi Shaked , Gili Dardikman
Abstract: A reconstruction system is presented for reconstructing morphology of biological cells. The system includes data input and output utilities, memory, and a data processor, and is configured for data communication with an image data provider to receive raw image data comprising a sequence of image frames acquired from the cell during a movement of the cell and being indicative of optical path delay (OPD) of light propagation through the biological cell. The data processor is configured and operable to process the raw image data and determine 3D dynamic morphological data of the cell. The data processor includes: a modeling utility; a position recovery module; and an analyzer module.
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公开(公告)号：US20250041603A1
公开(公告)日：2025-02-06
申请号：US18696392
申请日：2022-09-21
Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD. , Sheba Impact Ltd.
Inventor： Ben Meir MAOZ , Gil MARKOVICH , Amir ARAMI , Iftach SHLOMY
Abstract: Provided herein are devices, systems and methods for restoring tactile sensation in a subject, using a subcutaneously implanted nanogenerator which is connected to at least one of the subject's sensory nerves and is configured to produce an electric signal upon external stimulus and provide the electric signal to the sensory nerve to thereby stimulate the nerve in accordance with the external stimulus.
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公开(公告)号：US12204181B2
公开(公告)日：2025-01-21
申请号：US17668506
申请日：2022-02-10
Applicant: Ramot at Tel-Aviv University Ltd.
Inventor： Roei Aviram Cohen , Ofer Amrani , Shlomo Ruschin
Abstract: Structures for response shaping in frequency and time domain, include an optical response shaper and/or a modulator device with multiple injection. The device comprises a resonator having an enclosed geometric structure, for example a ring or racetrack structure, at least two injecting optical waveguides approaching the resonator to define at least two coupling regions between the resonator and the injecting waveguides, and may define at least two Free Spectral Range states. One or both of the coupling regions has a coupling coefficient selected for a predetermined frequency or time response, and the coupling coefficient or other device parameters may be variable, in some case in real time to render the response programmably variable. In addition, the injection power at one of the optical waveguides serves to modify the response.
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Patent Agency Ranking
公开(公告)号：US20250019456A1
公开(公告)日：2025-01-16
申请号：US18900759
申请日：2024-09-29
Applicant: Ramot at Tel-Aviv University Ltd.
Inventor： Lior MAYO , Adi TESSLER
IPC: C07K16/28 , A61K39/00 , A61P25/00 , G01N33/569
Abstract: A method of treating an inflammatory disease or disorder of the central nervous system (CNS) in a subject in need thereof is disclosed. The method comprising administering to the subject a therapeutically effective amount of an agent capable of binding CD157 on CD157-expressing cells of the CNS, the agent capable of mediating a therapeutic effect.
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公开(公告)号：US20240430011A1
公开(公告)日：2024-12-26
申请号：US18822532
申请日：2024-09-03
Applicant: Ramot at Tel-Aviv University Ltd.
Inventor： Yossef EHRLICHMAN , Ofer AMRANI , Shlomo RUSCHIN
IPC: H04B10/516 , G02F1/01 , G02F1/015 , G02F1/21 , G02F1/225 , G02F7/00 , H03M1/00 , H03M1/70 , H04B10/25 , H04B10/2575 , H04B10/50 , H04B10/54 , H04B10/556
Abstract: In a system for converting digital data into a modulated optical signal, an electrically controllable device, including a modulator having one or more actuating electrodes, provides an analog-modulated optical signal that is modulated in response to output data bits of a digital-to-digital mapping. A digital-to-digital conversion provides the mapping of input data words to the output data bits. The mapping enables adjustments to correct for non-linearities and other undesirable characteristics, thereby improving signal quality
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公开(公告)号：US12167153B2
公开(公告)日：2024-12-10
申请号：US18709524
申请日：2022-11-14
Applicant: Ramot at Tel-Aviv University Ltd.
Inventor： David Mendlovic , Dan Raviv , Khen Cohen , Lior Gelberg , Mor-Avi Azulay , Menahem Koren
IPC: H04N25/47 , H04N23/56 , H04N23/74 , H04N23/84 , H04N25/707
Abstract: A dynamic vision sensor (DVS) color camera (DVS-CCam) operable to acquire a color image of a scene, the DVS-CCam including a DVS photosensor comprising DVS pixels, an illuminator operable to transmit a light pattern characterized by temporal changes in intensity and color to illuminate a scene, an optical system configured to collect and focus on the pixels of the DVS photosensor light reflected by features in the scene from the light pattern transmitted by the illuminator, and a processor configured to process DVS signals generated by the DVS pixels responsive to temporal changes in the reflected light to provide a color image of the scene.
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公开(公告)号：US20240398906A1
公开(公告)日：2024-12-05
申请号：US18804150
申请日：2024-08-14
Inventor： Irit SAGI , Nikolaos A. AFRATIS , Inna SOLOMONOV , Carmit LEVY , Shivang PARIKH
Abstract: A method of treating a cancer which is characterized by an up-regulation of expression of lysyl oxidase (LOX) and heat shock protein 70 (HSP70) is disclosed. The method comprises administering to the subject a therapeutically effective amount of a polypeptide comprising a propeptide of lysyl oxidase (LOX), said polypeptide being devoid of LOX catalytic activity, wherein said polypeptide binds to both LOX and heat shock protein 70 (HSP70) with a EC50 of less than 100 nM.
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公开(公告)号：US20240316112A1
公开(公告)日：2024-09-26
申请号：US18674990
申请日：2024-05-27
Applicant: Ramot at Tel-Aviv University Ltd.
Inventor： Tal DVIR , Reuven EDRI , Lior WERTHEIM
IPC: A61K35/30 , A61K35/12 , A61L31/14 , C12N5/071 , C12N5/0793
CPC classification number: A61K35/30 , A61K35/12 , A61L31/145 , C12N5/0619 , C12N5/0679 , A61L2300/64 , A61L2430/38 , A61L2430/40 , C12N2501/999 , C12N2506/45
Abstract: A composition is disclosed which comprises a plurality of fibrous particles fabricated from decellularized omentum, the fibrous particles being between 750 microns-3 mm in diameter, wherein the fibrous particles comprise a network of mature neurons. Uses thereof and methods of generating same are also disclosed.
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