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1.发明公开公开(公告)号：US20240101456A1
公开(公告)日：2024-03-28
申请号：US18255858
申请日：2021-12-03
Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY , REGENTS OF THE UNIVERSITY OF MICHIGAN , BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
Inventor： Joshua BOLTZ , Bruce RITTMANN , Glen DAIGGER , Lynn KATZ
CPC classification number: C02F9/00 , B01D71/02 , C02F11/127
Abstract: The present invention relates to methods for biological wastewater treatment for Se control in Se-laden wastewater. The Se contaminants in the wastewater include the Se oxyanions selenate (SeO42-) and selenite (HSeO3−), which are biochemically reduced and transformed to elemental selenium (Se0) by microorganisms through anaerobic biological reduction. The resulting Se0 is entrained in the biomass, which is further processed to enable the efficient recovery of concentrated Se0.
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公开(公告)号：US20230401092A1
公开(公告)日：2023-12-14
申请号：US18249851
申请日：2021-10-22
Applicant: Arizona Board of Regents on Behalf of Arizona State University , Arizona Board of Regents on Behalf of the University of Arizona , Board of Regents, The University of Texas System , Carnegie Mellon University
Inventor： Umit Ogras , Radu Marculescu , Ali Akoglu , Chaitali Chakrabarti , Daniel Bliss , Samet Egemen Arda , Anderson Sartor , Nirmal Kumbhare , Anish Krishnakumar , Joshua Mack , Ahmet Goksoy , Sumit Mandal
CPC classification number: G06F9/4881 , G06F15/80
Abstract: Runtime task scheduling using imitation learning (IL) for heterogenous many-core systems is provided. Domain-specific systems-on-chip (DSSoCs) are recognized as a key approach to narrow down the performance and energy-efficiency gap between custom hardware accelerators and programmable processors. Reaching the full potential of these architectures depends critically on optimally scheduling the applications to available resources at runtime. Existing optimization-based techniques cannot achieve this objective at runtime due to the combinatorial nature of the task scheduling problem. In an exemplary aspect described herein, scheduling is posed as a classification problem, and embodiments propose a hierarchical IL-based scheduler that learns from an Oracle to maximize the performance of multiple domain-specific applications. Extensive evaluations show that the proposed IL-based scheduler approximates an offline Oracle policy with more than 99% accuracy for performance- and energy-based optimization objectives. Furthermore, it achieves almost identical performance to the Oracle with a low runtime overhead and high adaptivity.
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公开(公告)号：US20220238537A1
公开(公告)日：2022-07-28
申请号：US17583858
申请日：2022-01-25
Applicant: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA , BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM , GEORGIA TECH RESEARCH CORPORATION , THE TRUSTEES OF INDIANA UNIVERSITY , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Peter A. Dowben , Ruihua Cheng , Xiaoshan Xu , Alpha T. N'Diaye , Aaron Mosey , Guanhua Hao , Thilini K. Ekanayaka , Xuanyuan Jiang , Andrew J. Yost , Andrew Marshall , Azad J. Naeemi
IPC: H01L27/1159 , H01L29/51 , H01L29/78
Abstract: A thin film molecular memory is provided that satisfies criteria needed to make a molecular spintronic device, based on spin crossover complexes, competitive with silicon technology. These criteria include, device implementation, a low coercive voltage (less than 1V) and low write peak currents (on the order of 104 A/cm2), a device on/off ratio >10, thin film quality, the ability to “lock” the spin state (providing nonvolatility), the ability to isothermally “unlock” and switch the spin state with voltage, conductance change with spin state, room temperature and above room temperature operation, an on-state device resistivity less than 1 Ω·cm, a device fast switching speed (less than 100 ps), device endurance (on the order of 1016 switches without degradation), and the ability of having a device with a transistor channel width of 10 nm or below.
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公开(公告)号：US12063788B2
公开(公告)日：2024-08-13
申请号：US17583858
申请日：2022-01-25
Applicant: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA , BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM , GEORGIA TECH RESEARCH CORPORATION , THE TRUSTEES OF INDIANA UNIVERSITY , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Peter A. Dowben , Ruihua Cheng , Xiaoshan Xu , Alpha T. N'Diaye , Aaron Mosey , Guanhua Hao , Thilini K. Ekanayaka , Xuanyuan Jiang , Andrew J. Yost , Andrew Marshall , Azad J. Naeemi
CPC classification number: H10B51/30 , G11C11/5607 , H01L29/516 , H01L29/78391 , H10B61/10 , H10B61/22
Abstract: A thin film molecular memory is provided that satisfies criteria needed to make a molecular spintronic device, based on spin crossover complexes, competitive with silicon technology. These criteria include, device implementation, a low coercive voltage (less than 1V) and low write peak currents (on the order of 104 A/cm2), a device on/off ratio >10, thin film quality, the ability to “lock” the spin state (providing nonvolatility), the ability to isothermally “unlock” and switch the spin state with voltage, conductance change with spin state, room temperature and above room temperature operation, an on-state device resistivity less than 1 Ω·cm, a device fast switching speed (less than 100 ps), device endurance (on the order of 1016 switches without degradation), and the ability of having a device with a transistor channel width of 10 nm or below.
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5.发明公开公开(公告)号：US20230393637A1
公开(公告)日：2023-12-07
申请号：US18249876
申请日：2021-10-22
Applicant: Arizona Board of Regents on Behalf of Arizona State University , Arizona Board of Regents on Behalf of the University of Arizona , Board of Regents, The University of Texas System , Carnegie Mellon University
Inventor： Umit Ogras , Radu Marculescu , Ali Akoglu , Chaitali Chakrabarti , Daniel Bliss , Samet Egemen Arda , Anderson Sartor , Nirmal Kumbhare , Anish Krishnakumar , Joshua Mack , Ahmet Goksoy , Sumit Mandal
IPC: G06F1/26
CPC classification number: G06F1/26
Abstract: Hierarchical and lightweight imitation learning (IL) for power management of embedded systems-on-chip (SoCs), also referred to herein as HiLITE, is provided. Modern SoCs use dynamic power management (DPM) techniques to improve energy efficiency. However, existing techniques are unable to efficiently adapt the mntime decisions considering multiple objectives (e.g., energy and real-time requirements) simultaneously on heterogeneous platforms. To address this need, embodiments described herein propose HiLITE, a hierarchical IL framework that maximizes energy efficiency while satisfying soft real-time constraints on embedded SoCs. This approach first trains DPM policies using IL; then, it applies a regression policy at runtime to minimize deadline misses. HiLITE improves the energy-delay product by 40% on average, and reduces deadline misses by up to 76%, compared to state-of-the-art approaches. In addition, the trained policies not only achieve high accuracy, but also have negligible prediction time overhead and small memory footprint.
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Patent Agency Ranking
公开(公告)号：US20240004776A1
公开(公告)日：2024-01-04
申请号：US18249885
申请日：2021-10-22
Applicant: Arizona Board of Regents on Behalf of Arizona State University , Arizona Board of Regents on Behalf of the University of Arizona , Board of Regents, The University of Texas System , Carnegie Mellon University
Inventor： Umit Ogras , Radu Marculescu , Ali Akoglu , Chaitali Chakrabarti , Daniel Bliss , Samet Egemen Arda , Anderson Sartor , Nirmal Kumbhare , Anish Krishnakumar , Joshua Mack , Ahmet Goksoy , Sumit Mandal
CPC classification number: G06F11/3457 , G06N7/01 , G06F9/5038 , G06F11/3414
Abstract: A user-space emulation framework for heterogeneous system-on-chip (SoC) design is provided. Embodiments described herein propose a portable, Linux-based emulation framework to provide an ecosystem for hardware-software co-design of heterogenous SoCs (e.g., domain-specific SoCs (DSSoCs)) and enable their rapid evaluation during the pre-silicon design phase. This framework holistically targets three key challenges of heterogeneous SoC design: accelerator integration, resource management, and application development. These challenges are addressed via a flexible and lightweight user-space runtime environment that enables easy integration of new accelerators, scheduling heuristics, and user applications, and the utility of each is illustrated through various case studies. A prototype compilation toolchain is introduced that enables automatic mapping of unlabeled C code to heterogeneous SoC platforms. Taken together, this environment offers a unique ecosystem to rapidly perform functional verification and obtain performance and utilization estimates that help accelerate convergence towards a final heterogeneous SoC design.
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公开(公告)号：US12269805B2
公开(公告)日：2025-04-08
申请号：US17969519
申请日：2022-10-19
Inventor： Michael Holinstat , Reheman Adili , Andrew White , Theodore R. Holman
IPC: C07D249/12 , A61P7/02 , C07D403/12
Abstract: Disclosed herein are small molecule inhibitors of platelet function, and methods of using the small molecules to treat diseases, such as platelet hemostasis and thrombosis. In particular, disclosed herein are compounds of Formula (I) and pharmaceutically acceptable salts thereof: wherein the substituents are as described.
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8.发明申请公开(公告)号：US20250082571A1
公开(公告)日：2025-03-13
申请号：US18721326
申请日：2022-12-21
Applicant: Arizona Board of Regents on behalf of Arizona State University , Arizona Board of Regents on Behalf of the University of Arizona
Inventor： Abhinav Acharya , Hsin-Jung (Joyce) Wu
Abstract: The present invention provides a sustained drug release system comprising IL-2 and anti-IL-2 incorporated into a thermosensitive hydrogel that is engineered to be in liquid form at low temperatures for delivery, but form a hydrogel at physiological body temperatures to act as a sustained release platform. The thermostable hydrogel solution slowly releases IL-2 and anti-IL-2 to provide optimal concentrations for effective treatment of autoimmune diseases.
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公开(公告)号：US11981662B2
公开(公告)日：2024-05-14
申请号：US17964110
申请日：2022-10-12
Applicant: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM , THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Renato J. Aguilera , Subhas S. Karki , Sujeet Kumar , Manuel L. Penichet
IPC: C07D403/12 , A61K31/416 , A61K31/4192 , A61K31/454 , A61K31/5377 , A61K45/06 , A61P35/00 , A61P35/02 , C07D231/54 , C07D405/14
CPC classification number: C07D403/12 , A61K31/416 , A61K31/4192 , A61K31/454 , A61K31/5377 , A61K45/06 , A61P35/00 , A61P35/02 , C07D231/54 , C07D405/14
Abstract: The inventors have used a differential nuclear staining (DNS) assay to discover compounds with cytotoxic activity against the CEM cell line that has been determined to be highly sensitive to a variety of anti-cancer compounds. Compounds were synthesized based on a pyrazole backbone structure. Several newly synthesized compounds have been tested to identify the compounds with highest activity. One compound identified is the SSK-3 compound which has been tested on cancer cell lines and determined that it induced apoptosis via phosphatidylserine membrane exposure and activation of caspase 3 in the CEM lymphoma cell line.
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10.发明公开公开(公告)号：US20240059607A1
公开(公告)日：2024-02-22
申请号：US18222238
申请日：2023-07-14
Applicant: The Regents of the University of California , Arizona Board of Regents on Behalf of Arizona State University
Inventor： Gaurav Sant , Laurent G. Pilon , Bu Wang , Narayanan Neithalath , Zhenhua Wei , Benjamin Young , Gabriel D. Falzone , Dante Simonetti
CPC classification number: C04B7/19 , C04B7/46 , C04B7/38 , C04B9/20 , C04B40/0231 , C04B7/367 , C04B28/04 , C04B2111/00129
Abstract: A manufacturing process of a concrete product includes: (1) extracting calcium from solids as portlandite; (2) forming a cementitious slurry including the portlandite; (3) shaping the cementitious slurry into a structural component; and (4) exposing the structural component to carbon dioxide sourced from a flue gas stream, thereby forming the concrete product.
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