公开(公告)号：US10383556B2

公开(公告)日：2019-08-20

申请号：US12457332

申请日：2009-06-08

申请人： Kelley J. Lipman ,  Michael F. Tomasco ,  Daniel N. Brncic ,  David K. Hohl ,  Paul D. Reynolds ,  Raul Escutia

发明人： Kelley J. Lipman ,  Michael F. Tomasco ,  Daniel N. Brncic ,  David K. Hohl ,  Paul D. Reynolds ,  Raul Escutia

IPC分类号： G01N33/48 ,  A61B5/145 ,  A61B5/00

摘要： A medical diagnostic device includes a wirelessly transmitted time data receiver and processor. Associated devices, methods and functionality are also described.

公开(公告)号：US09782114B2

公开(公告)日：2017-10-10

申请号：US13566886

申请日：2012-08-03

申请人： Paul D. Reynolds ,  Raul Escutia ,  John F. Larkin ,  Charles Hu ,  Michael F. Tomasco ,  Daniel R. Bloom ,  Joseph A. Vivolo ,  Richard M. Wiard

发明人： Paul D. Reynolds ,  Raul Escutia ,  John F. Larkin ,  Charles Hu ,  Michael F. Tomasco ,  Daniel R. Bloom ,  Joseph A. Vivolo ,  Richard M. Wiard

IPC分类号： A61B5/1455 ,  A61B5/157 ,  A61B5/00 ,  A61B5/151 ,  A61B5/145 ,  G01N15/06 ,  G01N21/03 ,  G01N33/487 ,  G01N21/78 ,  A61B5/15

CPC分类号： A61B5/157 ,  A61B5/14507 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150083 ,  A61B5/150099 ,  A61B5/150114 ,  A61B5/150183 ,  A61B5/150305 ,  A61B5/150358 ,  A61B5/150389 ,  A61B5/150419 ,  A61B5/150519 ,  A61B5/150572 ,  A61B5/150755 ,  A61B5/150786 ,  A61B5/150809 ,  A61B5/150816 ,  A61B5/150824 ,  A61B5/150984 ,  A61B5/15109 ,  A61B5/15111 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15151 ,  A61B5/15161 ,  A61B5/15163 ,  A61B5/15176 ,  A61B5/15182 ,  A61B5/742 ,  A61B2562/0295 ,  G01N15/0612 ,  G01N21/03 ,  G01N21/78 ,  G01N33/487

摘要： Described here are meters and methods for sampling, transporting, and/or analyzing a fluid sample. The meters may include a meter housing and a cartridge. In some instances, the meter may include a tower which may engage one or more portions of a cartridge. The meter housing may include an imaging system, which may or may not be included in the tower. The cartridge may include one or more sampling arrangements, which may be configured to collect a fluid sample from a sampling site. A sampling arrangement may include a skin-penetration member, a hub, and a quantification member.

公开(公告)号：US08372015B2

公开(公告)日：2013-02-12

申请号：US11510784

申请日：2006-08-28

申请人： Raul Escutia ,  Jeffrey L. Emery ,  Craig M. Litherland ,  Jeffrey M. Jones ,  Gregory C. Loney ,  Michael F. Tomasco

发明人： Raul Escutia ,  Jeffrey L. Emery ,  Craig M. Litherland ,  Jeffrey M. Jones ,  Gregory C. Loney ,  Michael F. Tomasco

IPC分类号： A61B5/00 ,  A61B17/14 ,  A61B17/32 ,  A61B17/00 ,  B65D81/00

CPC分类号： A61B5/1411 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150099 ,  A61B5/150358 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/150748 ,  A61B5/15109 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15123 ,  A61B5/15125 ,  A61B5/15151 ,  A61B5/15161 ,  A61B5/157

摘要： An integrated monitoring and body fluid sampling device constructed to permit digital as well as alternate-site body fluid sampling and analysis, the device comprising: a housing; at least one skin-penetration member; and a member constructed for the application of circumferential or vacuum pressure to an appendage; wherein the member is detachably or retractably connected to the housing in a manner such that the integrated monitoring and body fluid sampling device can perform digital or alternate-site body fluid sampling and analysis. Additional arrangements and techniques are also described.

摘要翻译： 一种综合监测和体液采样装置，其被构造成允许数字和备用体液采样和分析，所述装置包括：壳体; 至少一个皮肤穿透部件; 以及为了向附属物施加周向或真空压力而构造的构件; 其中所述构件以使得所述综合监测和体液采样装置可以执行数字或替代站点体液采样和分析的方式可拆卸地或可缩回地连接到所述壳体。 还描述了附加的布置和技术。

公开(公告)号：US20070179405A1

公开(公告)日：2007-08-02

申请号：US11529614

申请日：2006-09-29

申请人： Jeffrey Emery ,  Craig Litherland ,  Raul Escutia ,  James Pfeiffer ,  Jeffrey Jones

发明人： Jeffrey Emery ,  Craig Litherland ,  Raul Escutia ,  James Pfeiffer ,  Jeffrey Jones

IPC分类号： A61B5/00 ,  G01N27/26 ,  G01N33/487

CPC分类号： A61B5/150984 ,  A61B5/1411 ,  A61B5/1427 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1468 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150076 ,  A61B5/150083 ,  A61B5/150099 ,  A61B5/150167 ,  A61B5/150229 ,  A61B5/150343 ,  A61B5/150389 ,  A61B5/150396 ,  A61B5/150412 ,  A61B5/150946 ,  A61B5/150954 ,  A61B5/150969 ,  A61B5/151 ,  A61B5/15111 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15121 ,  A61B5/15123 ,  A61B5/15146 ,  A61B5/15148 ,  A61B5/15151 ,  A61B5/15161 ,  A61B5/15163 ,  A61B5/15186 ,  A61B5/155 ,  A61B5/157 ,  A61B5/681 ,  A61B5/6824 ,  A61B5/6828 ,  A61B2560/0443 ,  A61B2560/0462 ,  G01N1/14 ,  G01N21/0303 ,  G01N21/77 ,  G01N27/416

摘要： An arrangement includes a housing, a plurality of sampling and analysis sites contained within the housing, each of the sampling and analysis sites having a skin-penetration member having a first end configured to pierce the skin, and an inner lumen in communication with the first end, an actuator operatively associated with the skin-penetration member, and an analyte quantification member in fluid communication with the inner lumen of the skin-penetration member. Integrated devices including such arrangements are also described.

摘要翻译： 一种装置包括壳体，容纳在壳体内的多个采样和分析位置，每个采样和分析位置具有皮肤穿透构件，其具有构造成刺穿皮肤的第一端，以及与第一 与皮肤穿透构件可操作地相关联的致动器以及与皮肤穿透构件的内腔流体连通的分析物定量构件。 还描述了包括这种布置的集成设备。

公开(公告)号：US20070078313A1

公开(公告)日：2007-04-05

申请号：US11239094

申请日：2005-09-30

申请人： Jeffrey Emery ,  Jeffrey Jones ,  Raul Escutia ,  Stephen Yee

发明人： Jeffrey Emery ,  Jeffrey Jones ,  Raul Escutia ,  Stephen Yee

IPC分类号： A61B5/00 ,  B65D81/00

CPC分类号： A61B5/15163 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150213 ,  A61B5/150358 ,  A61B5/150389 ,  A61B5/150519 ,  A61B5/15117 ,  A61B5/15153

摘要： Arrangements are provided including a fluid transport tube, or a needle, having a first end and a second end opposite the first end, and a lumen having an inner diameter. At least one fluid transport enhancing projection is disposed in the lumen and extends from the second end toward the first end. A discreet, wearable blood glucose monitor including such arrangements is also described.

摘要翻译： 提供了包括具有第一端和与第一端相对的第二端的流体输送管或针的布置以及具有内径的内腔。 至少一个流体输送增强突起设置在内腔中并且从第二端朝向第一端延伸。 还描述了包括这种布置的谨慎的，可戴式的血糖监测器。

公开(公告)号：US06179204B2

公开(公告)日：2001-01-30

申请号：US09420050

申请日：1999-10-18

申请人： James F. Blower ,  Frank D. Andruss ,  Todd A. Hansen ,  Galdino V. Ramirez ,  Raul Escutia

发明人： James F. Blower ,  Frank D. Andruss ,  Todd A. Hansen ,  Galdino V. Ramirez ,  Raul Escutia

IPC分类号： B65D522

CPC分类号： B65D5/22 ,  B31B50/46 ,  B31B50/732

摘要： A tray is assembled by automated equipment from a die cut blank. Tabs on opposing ends of side pieces are enfolded in rolled ends. A serrated edge on a distal edge of each rolled end is placed into a slit and crushed area to interlock the distal edge with the blank and form a tray with interlocked walls. The serrated edge does not penetrate the die cut blank, thus providing a leakproof, interlocked tray. Perforations define various fold lines to facilitate the use of automated equipment to form the tray. Release paper is placed on the central portion of the tray, with cake batter placed on the release paper. The batter can be baked into a cake while still in the tray.

摘要翻译： 托盘由自动化设备从模切坯料组装。 侧片的相对端的标签被卷成卷边。 每个轧制端的远端边缘上的锯齿状边缘被放置在狭缝和压碎区域中，以将远端边缘与坯料互锁，并形成具有互锁壁的托盘。 锯齿形边缘不穿透模切坯料，从而提供防漏，互锁的托盘。 穿孔定义各种折线以便于使用自动化设备来形成托盘。 释放纸放置在托盘的中央部分，将面糊放在脱模纸上。 面糊可以烘烤成蛋糕，而仍然在托盘。

公开(公告)号：US08012104B2

公开(公告)日：2011-09-06

申请号：US11941403

申请日：2007-11-16

申请人： Raul Escutia ,  Jeffrey L. Emery ,  Craig M. Litherland

发明人： Raul Escutia ,  Jeffrey L. Emery ,  Craig M. Litherland

IPC分类号： A61B5/00 ,  A61B17/14 ,  A61B17/32 ,  B65D81/00

CPC分类号： A61B5/150984 ,  A61B5/1411 ,  A61B5/1427 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1468 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150076 ,  A61B5/150083 ,  A61B5/150099 ,  A61B5/150167 ,  A61B5/150229 ,  A61B5/150343 ,  A61B5/150389 ,  A61B5/150396 ,  A61B5/150412 ,  A61B5/150946 ,  A61B5/150954 ,  A61B5/150969 ,  A61B5/151 ,  A61B5/15111 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15121 ,  A61B5/15123 ,  A61B5/15146 ,  A61B5/15148 ,  A61B5/15151 ,  A61B5/15161 ,  A61B5/15163 ,  A61B5/15186 ,  A61B5/155 ,  A61B5/157 ,  A61B5/681 ,  A61B5/6824 ,  A61B5/6828 ,  A61B2560/0443 ,  A61B2560/0462 ,  G01N1/14 ,  G01N21/0303 ,  G01N21/77 ,  G01N27/416

摘要： An arrangement for producing a sample of body fluid from a wound opening created in a skin surface at a sampling site includes at least one skin-penetration member having a first end configured to pierce the surface of the skin, and a inner lumen in communication with the first end; at least one actuator operatively associated with the at least one skin-penetration member; and at least one catalyst device configured to cause perfusion of body fluid at the sampling site; wherein the at least one actuator is configured to locate the at least one skin-penetration member so as to obstruct the wound opening while transporting body fluid through the inner lumen. Associated methods are also described.

公开(公告)号：US08012103B2

公开(公告)日：2011-09-06

申请号：US11529613

申请日：2006-09-29

申请人： Raul Escutia ,  Jeffrey L. Emery ,  Craig M. Litherland

发明人： Raul Escutia ,  Jeffrey L. Emery ,  Craig M. Litherland

IPC分类号： A61B5/00 ,  A61B17/14 ,  A61B17/32 ,  B65D81/00

CPC分类号： A61B5/150984 ,  A61B5/1411 ,  A61B5/1427 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1468 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150068 ,  A61B5/150076 ,  A61B5/150083 ,  A61B5/150099 ,  A61B5/150167 ,  A61B5/150229 ,  A61B5/150343 ,  A61B5/150389 ,  A61B5/150396 ,  A61B5/150412 ,  A61B5/150946 ,  A61B5/150954 ,  A61B5/150969 ,  A61B5/151 ,  A61B5/15111 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15121 ,  A61B5/15123 ,  A61B5/15146 ,  A61B5/15148 ,  A61B5/15151 ,  A61B5/15161 ,  A61B5/15163 ,  A61B5/15186 ,  A61B5/155 ,  A61B5/157 ,  A61B5/681 ,  A61B5/6824 ,  A61B5/6828 ,  A61B2560/0443 ,  A61B2560/0462 ,  G01N1/14 ,  G01N21/0303 ,  G01N21/77 ,  G01N27/416

摘要： An arrangement for producing a sample of body fluid from a wound opening created in a skin surface at a sampling site includes at least one skin-penetration member having a first end configured to pierce the surface of the skin, and a inner lumen in communication with the first end; at least one actuator operatively associated with the at least one skin-penetration member; and at least one catalyst device configured to cause perfusion of body fluid at the sampling site; wherein the at least one actuator is configured to locate the at least one skin-penetration member so as to obstruct the wound opening while transporting body fluid through the inner lumen. Associated methods are also described.

摘要翻译： 用于从在取样部位的皮肤表面产生的伤口开口产生体液样本的装置包括至少一个皮肤穿透部件，其具有构造成刺穿皮肤表面的第一端和与皮肤表面连通的内腔 第一端 与所述至少一个皮肤穿透构件可操作地相关联的至少一个致动器; 以及至少一个催化剂装置，其构造成在取样部位引起体液灌注; 其中所述至少一个致动器构造成定位所述至少一个皮肤穿透构件，以便在将体液输送通过所述内腔时阻塞所述伤口的开口。 还描述了相关方法。

公开(公告)号：USD601444S1

公开(公告)日：2009-10-06

申请号：US29300933

申请日：2008-05-30

申请人： Jeffrey M. Jones ,  Raul Escutia ,  Craig M. Litherland

设计人： Jeffrey M. Jones ,  Raul Escutia ,  Craig M. Litherland

公开(公告)号：US20070078358A1

公开(公告)日：2007-04-05

申请号：US11239123

申请日：2005-09-30

申请人： Raul Escutia ,  Jeffrey Emery

发明人： Raul Escutia ,  Jeffrey Emery

IPC分类号： A61B5/00

CPC分类号： A61B5/150343 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150213 ,  A61B5/150358 ,  A61B5/150389 ,  A61B5/150519 ,  A61B5/151 ,  A61B5/15117 ,  A61B5/15153 ,  A61B5/15163

摘要： Arrangements are provided including a base having a bore disposed therein extending from a first surface of the base through a second surface of the base, a fluid transport tube having a first end, a second end opposite the first end, and a lumen having an inner diameter, at least the second end of the tube being received within the bore of the base, and at least one fluid transport enhancing groove having at least a first section disposed in the second surface of the base and in fluid communication with the bore.

摘要翻译： 提供了一种布置，其具有设置在其中的孔的基部，其从基部的第一表面延伸穿过基部的第二表面;流体输送管，其具有第一端，与第一端相对的第二端和具有内部 所述管的至少第二端容纳在所述基座的孔内，以及至少一个流体输送增强凹槽，所述至少一个流体输送增强槽至少具有设置在所述基部的第二表面中并与所述孔流体连通的第一部分。