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公开(公告)号:US08986988B2
公开(公告)日:2015-03-24
申请号:US12680249
申请日:2008-09-29
申请人: Rohit Nandkumar Karnik , Seungpyo Hong , Ying Mei , Daniel Griffith Anderson , Jeffrey Michael Karp , Robert S. Langer , Suman Bose
发明人: Rohit Nandkumar Karnik , Seungpyo Hong , Ying Mei , Daniel Griffith Anderson , Jeffrey Michael Karp , Robert S. Langer , Suman Bose
IPC分类号: C12N5/07 , C12N5/00 , C12N5/0735 , C12N5/078 , C12M1/00
CPC分类号: C12N5/0068 , B01L3/502715 , B01L3/502761 , B01L2200/0647 , B01L2300/0877 , B01L2300/16 , C12M23/16 , C12M47/02 , C12N5/0062 , C12N2501/58 , C12N2501/585 , C12N2533/50 , C12N2533/52 , C12N2535/10
摘要: The present invention provides systems for cell separation based on cell rolling on surfaces along edges of regions coated with cell adhesion molecules. A variety of designs of coated regions and edges are disclosed.
摘要翻译: 本发明提供了基于在细胞粘附分子包被的区域的边缘上的表面上的细胞滚动的细胞分离系统。 公开了涂覆区域和边缘的各种设计。
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公开(公告)号:US20150174549A1
公开(公告)日:2015-06-25
申请号:US14523869
申请日:2014-10-25
申请人: Jong-Min Lim , Laura Marie Gilson , Sunandini Chopra , Omid Cameron Farokhzad , Rohit Nandkumar Karnik , Archana Swami
发明人: Jong-Min Lim , Laura Marie Gilson , Sunandini Chopra , Omid Cameron Farokhzad , Rohit Nandkumar Karnik , Archana Swami
IPC分类号: B01J19/06 , A61K9/51 , B01F15/02 , A61K31/713 , A61K47/48 , B01J19/26 , C01G49/02 , C09K11/02
CPC分类号: B01J19/06 , A61K9/5153 , A61K9/5192 , A61K31/713 , A61K47/59 , B01F5/045 , B01F5/0456 , B01F5/0458 , B01F2005/0025 , B01F2215/0431 , B01F2215/0459 , B01J19/0093 , B01J19/26 , B01J2219/00792 , B01J2219/00889 , C01G49/02 , C01P2004/04 , C01P2004/51 , C01P2004/64
摘要: A simple and versatile coaxial turbulent jet mixer can synthesize a range of nanoparticles at high throughput, while maintaining the advantages of homogeneity, reproducibility, and tunability that are normally accessible only in specialized microscale mixing devices. Rapid mixing down to a timescale of 7 ms can be achieved by controlling the Reynolds number, providing homogeneous and controllable environments for formation of nanoparticles, for example, by precipitation. The device fabrication does not require specialized machining, making it accessible for a wide range of biomedical laboratories.
摘要翻译: 简单且通用的同轴湍流喷射混合器可以以高通量合成一系列纳米颗粒,同时保持均匀性,再现性和可调性的优点,这些优点通常只能在专门的微米混合装置中使用。 通过控制雷诺数,可以快速混合到7 ms的时间范围,从而为形成纳米颗粒提供均匀和可控的环境,例如通过沉淀来实现。 设备制造不需要专门的加工,使其可以接触到广泛的生物医学实验室。
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公开(公告)号:US20100304485A1
公开(公告)日:2010-12-02
申请号:US12680249
申请日:2008-09-29
申请人: Rohit Nandkumar KARNIK , Seungpyo HONG , Ying MEI , Daniel Griffith ANDERSON , Jeffrey Michael KARP , Robert S. LANGER , Suman BOSE
发明人: Rohit Nandkumar KARNIK , Seungpyo HONG , Ying MEI , Daniel Griffith ANDERSON , Jeffrey Michael KARP , Robert S. LANGER , Suman BOSE
IPC分类号: C12N5/07 , C12M1/00 , C12M1/34 , C12N5/0775 , C12N5/0789 , C12N5/0735 , C12N5/09 , C12N5/078 , C12N5/0787 , C12N5/0786
CPC分类号: C12N5/0068 , B01L3/502715 , B01L3/502761 , B01L2200/0647 , B01L2300/0877 , B01L2300/16 , C12M23/16 , C12M47/02 , C12N5/0062 , C12N2501/58 , C12N2501/585 , C12N2533/50 , C12N2533/52 , C12N2535/10
摘要: The present invention provides systems for cell separation based on cell rolling on surfaces along edges of regions coated with cell adhesion molecules. A variety of designs of coated regions and edges are disclosed.
摘要翻译: 本发明提供了基于在细胞粘附分子包被的区域的边缘上的表面上的细胞滚动的细胞分离系统。 公开了涂覆区域和边缘的各种设计。
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