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公开(公告)号：US20090247530A1
公开(公告)日：2009-10-01
申请号：US12410801
申请日：2009-03-25
申请人： Bert NOLTE , Wolfgang SCHRODER , Klaus LINZ , Werner ENGLBERGER , Hans SCHICK , Heinz GRAUBAUM , Birgit ROLOFF , Sigrid OZEGOWSKI , Jozsef BALINT , Helmut SONNENSCHEIN
发明人： Bert NOLTE , Wolfgang SCHRODER , Klaus LINZ , Werner ENGLBERGER , Hans SCHICK , Heinz GRAUBAUM , Birgit ROLOFF , Sigrid OZEGOWSKI , Jozsef BALINT , Helmut SONNENSCHEIN
IPC分类号： A61K31/53 , C07D251/12 , C07D209/14 , A61K31/404 , A61P25/28
CPC分类号： C07D209/20 , A61K31/135 , A61K31/136 , A61K31/165 , A61K31/18 , A61K31/404 , A61K31/53 , A61K31/5377 , A61K45/06 , C07C211/40 , C07C211/54 , C07C215/14 , C07C215/42 , C07C217/74 , C07C223/04 , C07C229/16 , C07C233/36 , C07C233/40 , C07C233/41 , C07C233/62 , C07C233/79 , C07C235/54 , C07C237/06 , C07C237/24 , C07C275/24 , C07C311/07 , C07C311/18 , C07C311/37 , C07C2601/08 , C07C2601/14 , C07C2601/16 , C07D209/12 , C07D209/14 , C07D211/62 , C07D213/12 , C07D213/82 , C07D231/14 , C07D251/48 , C07D251/54 , C07D295/135 , C07D309/08 , C07D333/20 , C07D403/08 , C07D409/08
摘要： The invention relates to compounds that have an affinity to the μ-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain and other conditions.
摘要翻译： 本发明涉及对μ-阿片受体和ORL1-受体具有亲和力的化合物，其生产方法，含有这些化合物的药物以及这些化合物用于治疗疼痛和其它病症的用途。
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公开(公告)号：US20120202810A1
公开(公告)日：2012-08-09
申请号：US13454256
申请日：2012-04-24
申请人： Bert NOLTE , Wolfgang SHRÖDER , Klaus LINZ , Werner ENGLBERGER , Hans SCHICK , Heinz GRAUBAUM , Birgit ROLOFF , Sigrid OZEGOWSKI , József BÁLINT , Helmut SONNENSCHEIN
发明人： Bert NOLTE , Wolfgang SHRÖDER , Klaus LINZ , Werner ENGLBERGER , Hans SCHICK , Heinz GRAUBAUM , Birgit ROLOFF , Sigrid OZEGOWSKI , József BÁLINT , Helmut SONNENSCHEIN
IPC分类号： A61K31/404 , C07D251/48 , A61K31/53 , C07D413/12 , A61K31/5377 , A61P25/00 , A61P25/22 , A61P25/24 , A61P25/08 , A61P25/28 , A61P25/30 , A61P25/32 , A61P15/00 , A61P9/00 , A61P9/12 , A61P27/16 , A61P17/04 , A61P25/06 , A61P1/00 , A61P1/12 , A61P13/00 , A61P21/02 , A61P23/00 , A61P7/10 , A61P25/36 , C07D209/20
CPC分类号： C07D209/20 , A61K31/135 , A61K31/136 , A61K31/165 , A61K31/18 , A61K31/404 , A61K31/53 , A61K31/5377 , A61K45/06 , C07C211/40 , C07C211/54 , C07C215/14 , C07C215/42 , C07C217/74 , C07C223/04 , C07C229/16 , C07C233/36 , C07C233/40 , C07C233/41 , C07C233/62 , C07C233/79 , C07C235/54 , C07C237/06 , C07C237/24 , C07C275/24 , C07C311/07 , C07C311/18 , C07C311/37 , C07C2601/08 , C07C2601/14 , C07C2601/16 , C07D209/12 , C07D209/14 , C07D211/62 , C07D213/12 , C07D213/82 , C07D231/14 , C07D251/48 , C07D251/54 , C07D295/135 , C07D309/08 , C07D333/20 , C07D403/08 , C07D409/08
摘要： The invention relates to compounds that have an affinity to the μ-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain and other conditions.
摘要翻译： 本发明涉及对μ-阿片受体和ORL1-受体具有亲和力的化合物，其生产方法，含有这些化合物的药物以及这些化合物用于治疗疼痛和其它病症的用途。
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公开(公告)号：US08835689B2
公开(公告)日：2014-09-16
申请号：US13454256
申请日：2012-04-24
申请人： Bert Nolte , Wolfgang Schröder , Klaus Linz , Werner Englberger , Hans Schick , Heinz Graubaum , Birgit Roloff , Sigrid Ozegowski , József Bálint , Helmut Sonnenschein
发明人： Bert Nolte , Wolfgang Schröder , Klaus Linz , Werner Englberger , Hans Schick , Heinz Graubaum , Birgit Roloff , Sigrid Ozegowski , József Bálint , Helmut Sonnenschein
IPC分类号： C07C211/00 , C07C275/24 , C07D231/14 , C07C211/40 , C07C215/42 , C07D211/62 , C07D309/08 , C07C233/41 , C07D213/82 , C07C223/04 , A61K31/135 , C07C311/18 , C07D409/08 , C07C233/36 , C07D403/08 , C07C237/06 , C07D251/54 , C07D295/135 , C07C233/62 , C07C215/14 , C07C311/07 , C07C235/54 , C07D209/12 , C07D333/20 , C07C233/79 , C07D213/12 , C07C233/40 , A61K45/06 , C07C229/16 , C07C217/74 , C07D209/14
CPC分类号： C07D209/20 , A61K31/135 , A61K31/136 , A61K31/165 , A61K31/18 , A61K31/404 , A61K31/53 , A61K31/5377 , A61K45/06 , C07C211/40 , C07C211/54 , C07C215/14 , C07C215/42 , C07C217/74 , C07C223/04 , C07C229/16 , C07C233/36 , C07C233/40 , C07C233/41 , C07C233/62 , C07C233/79 , C07C235/54 , C07C237/06 , C07C237/24 , C07C275/24 , C07C311/07 , C07C311/18 , C07C311/37 , C07C2601/08 , C07C2601/14 , C07C2601/16 , C07D209/12 , C07D209/14 , C07D211/62 , C07D213/12 , C07D213/82 , C07D231/14 , C07D251/48 , C07D251/54 , C07D295/135 , C07D309/08 , C07D333/20 , C07D403/08 , C07D409/08
摘要： The invention relates to compounds that have an affinity to the μ-opioid receptor and the ORL 1-receptor, methods for their production, medications containing these compounds and the use of these compounds for the treatment of pain and other conditions.
摘要翻译： 本发明涉及对μ-阿片受体和ORL1-受体具有亲和力的化合物，其生产方法，含有这些化合物的药物以及这些化合物用于治疗疼痛和其它病症的用途。
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