Abstract:
The invention relates to novel pyrimidine derivatives of Formula (1) which are efficacious inhibitors of protein kinases, in particular of one or more isoforms of the protein kinase B/Akt.
Abstract:
A liquid recording apparatus ejects droplets of liquid onto a recording medium. The apparatus has multiple liquid emitters whose emissions are activated by multiple power pulses. The power pulses are controlled to maximize the number of emitters which can be simultaneously energized while keeping the instantaneous power usage within prescribed boundaries. The multiple emitters are organized into banks of emitters whose numbers are small enough that all emitters within a bank can receive a correct level of power simultaneously without exceeding capacity of a shared power source. A circuit interleaves the power pulses to the emitters so that no bank of emitters are receiving power at the same instant of time.
Abstract:
Compounds of a certain formula I in which R1, R2, R3 and R4 have the meanings indicated in the description are novel compounds expected to be useful in the therapy of (hyper)proliferative diseases and/or disorders responsive to induction of apoptosis.
Abstract:
A real-time integrated navigation system for a vehicle includes a GPS receiver, connected to a first antenna, where the GPS receiver receives GPS data from satellites and outputs GPS position data. The system also includes a communications link, connected to a second antenna and to the GPS receiver, receiving range and carrier phase measurements from at least one base station. The system further includes navigation aids which provide relative position data of said vehicle and a Kalman filter, connected to the output of the GPS receiver and the navigation aids, that integrates the GPS position data and the relative position data and outputs smoothed position data. The smoothed position data is used in transportation applications, especially detection of lane departure. This GPS-based positioning system is suitable for highway speeds during all weather conditions.
Abstract:
The invention relates to a wireless remote control system (100) for vehicle functions (13.1, 13.2), having a portable remote control unit (20) which comprises operator control elements for activating control signals which are exchanged with a vehicle mounted transmitter/receiver unit (11) in order to control the vehicle functions (13.1, 13.2). According to the invention, the remote control unit (20) comprises the following components: at least one first operator control element which has a predefined function of an electronic driving authorization and/or access authorization system (13.2) assigned to it, and at least one second operator control element and at least one display unit for menu prompted control of at least one ride level control system (13.1).
Abstract:
Methods and apparatus for characterising OSI-materials provide for: introducing the material into a measurement cell; subjecting the material to a gas mixture containing oxygen; permitting a certain time or at certain time interval or intervals to elapse; measuring a defined volume part of the gas mixture with regard to its oxygen concentration using a measurement circuit, which together with the time component represents a characterisation of the OSI-material, wherein the OSI-material in the measurement cell is subjected to the gas mixture circulated in a closed reaction circuit, and the defined volume part is conveyed into a measurement circuit containing a gas, for the measurement of the oxygen concentration.
Abstract:
The present invention relates to a bifunctional compound of formula I or its pharmaceutically acceptable salts or solvates A-L-B (I) wherein A is a histone deacetylase (HDAC) inhibitory moiety, L is a single bond or a linker group and B is a protein kinase inhibitory moiety. The bifunctional compound according to formula (I) is useful for the treatment of malignant and non-malignant neoplasia and diseases related to abnormal cell growth.
Abstract:
The invention relates to a novel conditioning agent based on polysuccinimide, its hydrolysates or its partial hydrolysates, for preventing deposits in standing or flowing water systems.
Abstract:
Radar sensor for motor vehicles, having a transmitting and receiving device for microwaves, in which beam-shaping devices which are independent of one another are provided for the azimuth and the elevation, and the beam-shaping device for the elevation has a cylindrical lens.