公开(公告)号：US12215089B1

公开(公告)日：2025-02-04

申请号：US18081409

申请日：2022-12-14

Applicant: Triad National Security, LLC ,  The United States of America, as represented by the Secretary of the Army

Inventor： David Chavez ,  Jesse Sabatini ,  Pablo Guzmán ,  Leah Wingard ,  Eric Johnson

IPC: C07D271/06 ,  C06B25/34

Abstract: Disclosed herein are embodiments of an energetic compound and methods of making and using the same. Energetic compound embodiments disclosed herein exhibit physical and chemical properties that facilitate their use in various applications, such as high energy propellant plasticizers, melt-castable explosives, and the like. Efficient and safe method embodiments for making the disclosed energetic compound embodiments are described herein.

公开(公告)号：US12195320B1

公开(公告)日：2025-01-14

申请号：US17984621

申请日：2022-11-10

Applicant: Triad National Security, LLC

Inventor： Eric L. Brosha ,  Rangachary Mukundan ,  Christopher J. Romero

IPC: G01N27/407 ,  B67D7/08 ,  B67D7/32 ,  B67D7/36 ,  B67D7/76 ,  B67D7/04

Abstract: A fuel contamination detection system includes a fuel quality analyzer, a multiway valve, and a controller. The multiway valve includes a first inlet, a second inlet, and an outlet. The multiway valve also may include a switching device. The controller is electrically coupled to the analyzer. The controller may be coupled to the switching device, if present. Fuel is flowed through the fuel quality analyzer and an output current is measured to determine whether the fuel includes impurities. The controller is operable to signal a fuel dispensing system to dispense fuel if the fuel is sufficiently clean or cease dispensing fuel if the fuel is impure.

公开(公告)号：US12176113B1

公开(公告)日：2024-12-24

申请号：US17176752

申请日：2021-02-16

Applicant: Triad National Security, LLC

Inventor： Robert Stowers Reid

IPC: G21C15/08 ,  G21C5/02 ,  G21C15/02 ,  G21C15/04 ,  G21C15/257

Abstract: A heat pipe cooled nuclear reactor core (“reactor core”) includes an array of fuel, an array of primary heat rejection heat pipes, and an array of moderator cooling heat pipes or thermosiphons. Each moderator cooling heat pipe in the array of moderator cooling heat pipes is surrounded by metal hydride moderator materials, slowing neutrons from a fission energy range to a lower energy range in the reactor core.

公开(公告)号：US12133937B1

公开(公告)日：2024-11-05

申请号：US17492415

申请日：2021-10-01

Applicant: Triad National Security, LLC

Inventor： Graham Burton Arinder ,  Joshua Scott Bort ,  Eric Richard Olivas ,  John David Bernardin

IPC: A61L9/20

Abstract: Examples of air treatment systems for use in neutralizing airborne pathogens are disclosed herein. The air treatment systems comprise a housing, an air moving device, and one or more sources of ultraviolet light. An airflow may be directed through the enclosure by the air moving device and exposed to the ultraviolet light sources disposed within the enclosure. In some examples, the air treatment systems include one or more baffles disposed within the enclosure to disrupt the linear flow of air through the enclosure and cause more uniform exposure to the ultraviolet light emitted by the sources of ultraviolet light. Some examples may also include one or more air filters for removing particulate matter.

公开(公告)号：US12018066B1

公开(公告)日：2024-06-25

申请号：US17514903

申请日：2021-10-29

Applicant: Triad National Security, LLC

Inventor： Antonietta Maria Lillo ,  Nileena Velappan ,  Geoffrey S. Waldo

IPC: C07K16/00 ,  C07K16/10

CPC classification number: C07K16/10 ,  C07K2317/33 ,  C07K2317/622 ,  C07K2317/92

Abstract: The invention provides antibodies that specifically bind the SARS-CoV-2 receptor binding domain. The antibodies are useful in treating SARS-CoV-2 virus infection and in diagnostic methods, agents, and kits thereof.

公开(公告)号：US12007171B1

公开(公告)日：2024-06-11

申请号：US17216398

申请日：2021-03-29

Applicant: Triad National Security, LLC

Inventor： Robert Stowers Reid ,  Morgan T. Biel ,  Lindsey M. Gaspar ,  Kirk Weisbrod ,  Katrina M. Sweetland ,  Robert A. Zimmerman

IPC: F28D15/04 ,  B23K31/02 ,  B23P15/26

CPC classification number: F28D15/046 ,  B23K31/027 ,  B23P15/26 ,  B23P2700/09 ,  F28F2275/061

Abstract: A method for forming an annular heat pipe wick in a controlled atmosphere includes wrapping a plurality of layers of a fine mesh screen around a mandrel to form a wick. The method also includes inserting the mandrel and the wick into a sheath, and compressing the wick between the sheath and the mandrel to form an assembly. The compressing of the wick comprises applying pressure to an exterior of the mandrel and the sheath. The method further includes diffusion bonding the assembly at a temperature sufficiently high achieving self-diffusion of the plurality of layers of the fine mesh screen used to form the wick to themselves. The method also includes cooling the diffusion bonded assembly to room temperature, and etching the mandrel and sheath from the diffusion bonded assembly, leaving the wick as a porous tube.

公开(公告)号：US11946834B1

公开(公告)日：2024-04-02

申请号：US17514945

申请日：2021-10-29

Applicant: Triad National Security, LLC

Inventor： Ann Junghans ,  Eric Davis ,  Cristian Pantea ,  Rollin Lakis ,  Vlad Henzl

IPC: G01N1/00 ,  G01N1/04 ,  G01N1/36 ,  G01N1/40 ,  G01N21/65 ,  G01N33/22 ,  G01N1/02

CPC classification number: G01N1/04 ,  G01N1/36 ,  G01N1/4077 ,  G01N21/658 ,  G01N33/227 ,  G01N2001/028 ,  G01N2001/4094

Abstract: A method of sample collection includes collecting an analyte from a sampling surface using a rapidly curable liquid gel comprising one or more metal particles; co-aggregating the one or more metal particles from the rapidly curable liquid gel and the analyte from the sampling surface; and rapidly curing the rapidly curable liquid gel. The composition and sample preparation conditions may facilitate improved collection efficiency of analytes during environmental and forensic evidence sampling. In addition, the composition and sample preparation conditions may facilitate enhanced detection and identification of the analyte using e.g., Surface Enhanced Raman Spectrometry (SERS).

公开(公告)号：US11884704B2

公开(公告)日：2024-01-30

申请号：US17199319

申请日：2021-03-11

Applicant: Duke University ,  Triad National Security, LLC

Inventor： Barton F. Haynes ,  Mattia Bonsignori ,  Hua-Xin Liao ,  Bette T. Korber ,  Peter T. Hraber ,  Kevin O. Saunders

IPC: C07K14/005 ,  A61K39/21 ,  A61K39/39 ,  A61K45/06 ,  C12N7/00 ,  A61K39/00

CPC classification number: C07K14/005 ,  A61K39/21 ,  A61K39/39 ,  A61K45/06 ,  C12N7/00 ,  A61K2039/545 ,  C12N2740/16122 ,  C12N2740/16134

Abstract: In certain aspects the invention provides HIV-1 immunogens, including HIV-1 envelope selections from individual CH505, and methods for swarm immunizations using combinations of HIV-1 envelopes.

公开(公告)号：US20230362225A1

公开(公告)日：2023-11-09

申请号：US18219976

申请日：2023-07-10

Applicant: TRIAD National Security, LLC.

Inventor： David Palmer

IPC: H04L65/70 ,  H04L27/36 ,  H04L69/04 ,  H04B7/216 ,  H04B7/24 ,  H04J13/10

CPC classification number: H04L65/70 ,  H04L27/36 ,  H04L69/04 ,  H04B7/216 ,  H04B7/24 ,  H04J13/10

Abstract: Techniques for framing data in various data transmission contexts are described. A data framing technique may include a transmitter sending a data stream including repeating bits in alternating forward and reverse order. A receiver of the data stream may fold the data stream, and correlate portions of the folded data stream for purposes of validating the data stream and/or identifying an ID in the data stream. In at least some instances, once the receiver validates the data stream, the receiver may accept payload accompanying the data stream.

公开(公告)号：US11786597B2

公开(公告)日：2023-10-17

申请号：US16448335

申请日：2019-06-21

Applicant: The Regents of the University of California ,  Triad National Security, LLC ,  Arizona Board of Regents

Inventor： Michael Zakrewsky ,  Samir Mitragotri ,  David T. Fox ,  Andrew Koppisch ,  Rico Del Sesto ,  Katherine Lovejoy

IPC: A01N3/00 ,  A61K31/215 ,  A01N37/12 ,  A01N37/44 ,  A61K31/24 ,  A01N25/00 ,  A61K47/24 ,  A61K9/00 ,  A61K47/12 ,  A01N33/12 ,  A01N43/36 ,  A61K31/047 ,  A61K31/545 ,  A61K31/66

CPC classification number: A61K47/24 ,  A01N33/12 ,  A01N43/36 ,  A61K9/0014 ,  A61K31/047 ,  A61K31/545 ,  A61K31/66 ,  A61K47/12 ,  A01N43/36 ,  A01N41/06 ,  A01N33/12 ,  A01N37/02 ,  A01N37/04 ,  A01N37/06 ,  A01N41/06 ,  A01N47/28 ,  A01N49/00

Abstract: The compositions and methods described herein are topically applied to the skin with negligible or no skin irritation and can direct or prevent transport through the skin. The compositions contain neat ionic liquids, optionally in combination with a drug to be delivered. In a preferred embodiment, the compositions increase transdermal transport of the drug to be delivered. In some embodiments, the compositions disrupt bacterial biofilms. This is particularly beneficial in the treatment of antibiotic resistant skin infections. In other embodiments, the compositions direct delivery within the skin. In still other embodiments, the compositions prevent transfer of substances through the stratum corneum. The disclosed compositions and methods can be tuned and modified such that they can be used to treat or prevent a variety of different diseases and disorders.