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1.发明授权公开(公告)号：US09044140B2
公开(公告)日：2015-06-02
申请号：US11631121
申请日：2005-06-30
CPC分类号： A61B5/0059 , A61N5/0601 , A61N5/062
摘要： An instrument for photodynamic therapy applies treatment light from a dye laser, white light, and ultraviolet fluorescence excitation light from an LED onto a lesion and surrounding areas in a time-multiplexed manner. The reflected white light is analyzed in a spectrometer to determine a correction for the dynamic optical spectral properties of the patient's tissue. Light emitted by fluorescence from the lesion and the surrounding areas is analyzed in another spectrometer, and the results are corrected in a computer, using the correction. An optical switch has been developed for the instrument, using a bistable solenoid and a sled.
摘要翻译： 用于光动力学治疗的仪器将来自染料激光，白光和来自LED的紫外线荧光激发光的处理光以时间复用的方式应用于病变和周围区域。 在光谱仪中分析反射的白光，以确定对患者组织的动态光谱特性的校正。 在另一个光谱仪中分析来自损伤和周围区域的荧光发出的光，并使用校正在计算机中校正结果。 已经开发了用于仪器的光学开关，使用双稳态螺线管和滑轨。
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2.发明申请METHODS AND APPARATUS FOR A FIBER OPTIC DISPLAY SCREEN HAVING AN ADJUSTABLE SIZE 有权用于具有可调节尺寸的光纤显示屏的方法和装置公开(公告)号：US20120155800A1
公开(公告)日：2012-06-21
申请号：US12973152
申请日：2010-12-20
CPC分类号： G02B6/4298 , G02B6/04 , G02B6/262 , G09F9/305
摘要： Methods and apparatus for a fiber optic display screen of adjustable size. In one embodiment, a screen comprises: a plurality of pixels formed by a terminal end of at least one optical fiber, wherein the pixels are substantially equidistant from each other along a first axis in a first screen size and in a second screen size that is larger than the first size.
摘要翻译： 可调节尺寸的光纤显示屏的方法和装置。 在一个实施例中，屏幕包括：由至少一个光纤的终端形成的多个像素，其中所述像素沿着第一屏幕尺寸的第一轴线和第二屏幕尺寸彼此基本上等距离， 大于第一大小。
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3.发明申请公开(公告)号：US20090043296A1
公开(公告)日：2009-02-12
申请号：US11631121
申请日：2005-06-30
CPC分类号： A61B5/0059 , A61N5/0601 , A61N5/062
摘要： An instrument for photodynamic therapy applies treatment light from a dye laser, white light, and ultraviolet fluorescence excitation light from an LED onto a lesion and surrounding areas in a time-multiplexed manner. The reflected white light is analyzed in a spectrometer to determine a correction for the dynamic optical spectral properties of the patient's tissue. Light emitted by fluorescence from the lesion and the surrounding areas is analyzed in another spectrometer, and the results are corrected in a computer, using the correction. An optical switch has been developed for the instrument, using a bistable solenoid and a sled.
摘要翻译： 用于光动力学治疗的仪器将来自染料激光，白光和来自LED的紫外线荧光激发光的处理光以时间复用的方式应用于病变和周围区域。 在光谱仪中分析反射的白光，以确定对患者组织的动态光谱特性的校正。 在另一个光谱仪中分析来自损伤和周围区域的荧光发出的光，并使用校正在计算机中校正结果。 已经开发了用于仪器的光学开关，使用双稳态螺线管和滑轨。
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公开(公告)号：US08594475B2
公开(公告)日：2013-11-26
申请号：US12973010
申请日：2010-12-20
CPC分类号： G02B6/06
摘要： Methods and apparatus for a fiber optic display system. In one embodiment, a fiber optic display screen comprises a laser source, relay optics to receive an output from the laser source, condenser optics coupled to the relay optics, a digital pixelator coupled to the condenser optics, a fiber optic transmission line coupled to the digital pixelator, and a fiber optic screen provided by terminal ends of fibers in the fiber optic transmission line.
摘要翻译： 光纤显示系统的方法和装置。 在一个实施例中，光纤显示屏幕包括激光源，用于接收来自激光源的输出的中继光学器件，耦合到中继光学器件的聚光器光学器件，耦合到聚光镜的数字像素器，耦合到该光纤传输线的光纤传输线 数字像素仪，以及由光纤传输线中的光纤终端提供的光纤屏幕。
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公开(公告)号：US07106456B1
公开(公告)日：2006-09-12
申请号：US10146156
申请日：2002-05-15
申请人： William J. Cottrell
发明人： William J. Cottrell
CPC分类号： G01J9/02 , G01J2009/0223 , G01J2009/0261 , G01M11/005 , G01M11/331 , G01M11/333
摘要： A common-path, point-diffraction, phase-shifting interferometer uses a half wave plate having a diffractive element, such as pin hole. A coherent, polarized light source simultaneously generates a reference beam from the diffractive element and an object beam from remaining portions of the light going through the half wave plate. The reference beam has a nearly spherical wavefront. Each of the two beams possesses a different polarization state. The object and reference beams are then independently phase modulated by a polarization sensitive phase modulator that shifts phase an amount depending on applied voltage and depending on polarization state of the incident light. A polarizer is then used to provide the object and reference beams in the same polarization state with equal intensities so they can interfere to create an interferogram with near unity contrast.
摘要翻译： 公共路径，点衍射，相移干涉仪使用具有诸如针孔的衍射元件的半波片。 相干偏振光源同时从衍射元件产生参考光束，并且从通过半波片的光的剩余部分产生物体光束。 参考光束具有近似球面的波前。 两个光束中的每一个具有不同的偏振状态。 物体和参考光束然后通过偏振敏感相位调制器独立相位调制，偏振相位调制器根据施加的电压和取决于入射光的偏振状态移相量。 然后使用偏振器以相同的强度在相同的极化状态下提供物体和参考光束，因此它们可以干扰以产生具有近乎一致的对比度的干涉图。
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6.发明申请METHOD FOR CONTROLLING PHOTODYNAMIC THERAPY IRRADIATION AND RELATED INSTRUMENTATION 审中-公开用于控制光化学治疗辐射和相关仪器的方法公开(公告)号：US20100292762A1
公开(公告)日：2010-11-18
申请号：US12738196
申请日：2008-10-20
IPC分类号： A61N5/06
CPC分类号： A61N5/062
摘要： In a first embodiment, there is no monitoring, and instead light is delivered according to a predetermined ‘recipe.’ In a second embodiment, the instrumentation provides a means for making the reflectance measurements during therapy without requiring the brief interruption. This device may therefore allow more accurate measurement of treatment-induced changes to the reflectance measurement. In a third embodiment, an adjustable aperture is used to constrict the area of a treatment beam.
摘要翻译： 在第一实施例中，没有监视，而是根据预定的“配方”传送光。在第二实施例中，仪器提供了在治疗期间进行反射测量的手段，而不需要短暂的中断。 因此，该装置可以更准确地测量治疗引起的反射测量的变化。 在第三实施例中，可调节的孔用于收缩治疗束的面积。
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7.发明申请SIDE-FIRING LINEAR FIBER OPTIC ARRAY FOR INTERSTITIAL OPTICAL THERAPY AND MONITORING USING COMPACT HELICAL GEOMETRY 审中-公开用于间断光学治疗的边缘线性光纤阵列和使用紧凑的螺旋形几何测量公开(公告)号：US20090221921A1
公开(公告)日：2009-09-03
申请号：US12296886
申请日：2007-04-09
申请人： William J. Cottrell , Thomas Foster
发明人： William J. Cottrell , Thomas Foster
CPC分类号： A61B18/22 , A61B5/0071 , A61B5/0075 , A61B18/24 , A61B2018/1807 , A61B2018/2216 , A61N5/0601 , A61N5/062 , A61N2005/0662 , A61N2005/067 , G02B6/06
摘要： An optical probe has multiple side-firing optical fibers which terminate in a linearly staggered fashion. A central fiber can be used as well. In diagnostic techniques, one fiber can be used as an emitter, while the others are used as receivers, or various fibers can be used as emitters and receivers at different times to form a map of the area. In therapeutic techniques, the treatment light can be emitted from the fibers in parallel or in sequence, and the fluence can be independently adjusted for each of the fibers.
摘要翻译： 光学探针具有以线性交错方式终止的多个侧射光纤。 也可以使用中心纤维。 在诊断技术中，一根光纤可以用作发射器，而其他光纤可以用作接收器，或者各种光纤可以在不同时间用作发射器和接收器，以形成该区域的映射。 在治疗技术中，处理光可以从纤维平行或顺序发射，并且可以针对每个纤维独立地调节注量。
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公开(公告)号：US06429958B1
公开(公告)日：2002-08-06
申请号：US09815975
申请日：2001-03-22
IPC分类号： G02B2600
CPC分类号： G02B6/29358 , G02B6/264 , G02B6/29311 , G02B6/2938 , G02B27/286 , G02F1/0147 , G02F1/19
摘要： The optical assembly for modulating input light and providing modulated light at an output thereof includes a first arrangement, which includes a layer of a superconductive material having at least a part of the input light incident thereon as incident light. The superconductive material is switchable between a first state, in which the superconductive material exhibits a first refractive index, and a second state, in which the superconductive material exhibits a second refractive index. The first arrangement is configured to direct to the output as the modulated light a first fraction of the incident light, when the superconductive material is in the first state, and a second fraction of the incident light, when the superconductive material is in the second state, such that the modulated light exhibits a given value of extinction ratio, which is defined as a ratio of the first fraction of the incident light to the second fraction of the incident light at the output. The optical assembly further includes a second arrangement cooperating with the first arrangement to provide at the output of the optical assembly another value of the extinction ratio that is smaller than the given value.
摘要翻译： 用于调制输入光并在其输出处提供调制光的光学组件包括第一布置，其包括具有入射到其上的入射光的至少一部分作为入射光的超导材料层。 超导材料可以在超导材料表现出第一折射率的第一状态和超导材料呈现第二折射率的第二状态之间切换。 第一布置被配置为当超导材料处于第一状态时将调制光作为入射光的第一部分指向入射光的第一部分，并且当超导材料处于第二状态时，引导入射光的第二部分 使得调制的光呈现给定的消光比值，其被定义为入射光的第一分数与在输出处的入射光的第二分数的比率。 光学组件还包括与第一布置配合的第二布置，以在光学组件的输出处提供小于给定值的消光比的另一值。
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9.发明授权Methods and apparatus to receive light from a laser via air for a fiber optic display 有权用于通过空气从光学器件接收来自光纤显示器的光的方法和装置公开(公告)号：US08602606B2
公开(公告)日：2013-12-10
申请号：US12973081
申请日：2010-12-20
IPC分类号： F21V17/02
CPC分类号： G02B6/06 , H01S3/0071
摘要： Methods and apparatus for a free space coupler to receive light from a laser via air. In one embodiment, a system comprises a laser source, a mirror optically aligned to the laser source, a first mount to control a position of the mirror, a free-space coupler to receive light from the mirror, a beam splitter to receive light exiting the coupler, a first detector to receive light reflected from the beam splitter, a second mount coupled to the first detector and to the coupler to control a position of the coupler from information from the first detector, and a second detector to receive light reflected by the coupler and the mirror, wherein the second detector is coupled to the first mount for positioning the mirror with respect to the coupler.
摘要翻译： 用于通过空气从激光器接收光的自由空间耦合器的方法和装置。 在一个实施例中，系统包括激光源，与激光源光学对准的反射镜，用于控制反射镜位置的第一安装件，用于接收来自反射镜的光的自由空间耦合器，用于接收离开的光的分束器 耦合器，用于接收从分束器反射的光的第一检测器，耦合到第一检测器和耦合器的第二安装件，用于根据来自第一检测器的信息控制耦合器的位置，以及第二检测器，用于接收由 耦合器和反射镜，其中第二检测器耦合到第一安装件，用于相对于耦合器定位反射镜。
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10.发明授权Methods and apparatus for a fiber optic display screen having an adjustable size 有权具有可调节尺寸的光纤显示屏的方法和装置公开(公告)号：US08515222B2
公开(公告)日：2013-08-20
申请号：US12973152
申请日：2010-12-20
CPC分类号： G02B6/4298 , G02B6/04 , G02B6/262 , G09F9/305
摘要： Methods and apparatus for a fiber optic display screen of adjustable size. In one embodiment, a screen comprises: a plurality of pixels formed by a terminal end of at least one optical fiber, wherein the pixels are substantially equidistant from each other along a first axis in a first screen size and in a second screen size that is larger than the first size.
摘要翻译： 可调节尺寸的光纤显示屏的方法和装置。 在一个实施例中，屏幕包括：由至少一个光纤的终端形成的多个像素，其中所述像素沿着第一屏幕尺寸的第一轴线和第二屏幕尺寸彼此基本上等距离， 大于第一大小。
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