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18 条记录 (耗时 0.028 秒)

    Ion-exchange resin/enzyme activity assay
    1.
    发明授权
    Ion-exchange resin/enzyme activity assay 失效
    离子交换树脂/酶活性测定

    公开(公告)号：US06927037B2

    公开(公告)日：2005-08-09

    申请号：US09888008

    申请日：2001-06-22

    申请人： Thomas P. Kasten ,  Mark G. Currie ,  William M. Moore ,  Kay Broschat

    发明人： Thomas P. Kasten ,  Mark G. Currie ,  William M. Moore ,  Kay Broschat

    IPC分类号： C12Q1/00 ,  C12Q1/48 ,  C12Q1/15

    CPC分类号： C12Q1/00 ,  C12Q1/485

    摘要： The present invention relates to a rapid high-throughput ion-exchange resin assay for determining enzyme activity. This novel assay uses a radiometric technique which separates the radioactive substrate from the product (or the radioactive product from the substrate) by exploiting the differences in the net charges of the molecules using ion-exchange resin. This assay is useful, for example, for studies of enzyme kinetics, the identification of functional sites in the enzyme, and in the automated screening of compound libraries for pharmaceutical drug development.

    摘要翻译： 本发明涉及用于测定酶活性的快速高通量离子交换树脂测定法。 这种新型测定法使用辐射技术，其通过使用离子交换树脂利用分子的净电荷差异将放射性底物与产物（或放射性产物与底物）分离。 该测定法可用于例如酶动力学的研究，酶的功能位点的鉴定以及用于药物开发的化合物文库的自动筛选。

    Thermal engine system
    3.
    发明授权
    Thermal engine system 失效
    热力发动机系统

    公开(公告)号：US4031704A

    公开(公告)日：1977-06-28

    申请号：US714300

    申请日：1976-08-16

    申请人： Marvin L. Moore ,  William M. Moore

    发明人： Marvin L. Moore ,  William M. Moore

    IPC分类号： F03G7/06 ,  F04B17/00

    CPC分类号： F03G7/06 ,  F04B17/00

    摘要： A thermal engine system is characterized by a cylinder having a suitable working fluid disposed therein and having a piston reciprocally movable in first and second directions within the cylinder, the piston dividing the cylinder into first and second pressurization regions. In one embodiment, a thermally responsive, expansible member is operatively connected directly at one free terminus thereof to the piston. In an alternate embodiment, the free terminus of the thermally responsive, expansible member is indirectly attached to one or more double-acting piston-cylinders through lever connections. The thermally responsive, expansible member is connected at the second end thereof to suitable means for maintaining the second end of the expansible member in a substantially stationary position. The thermally responsive, expansible member responds to the temperature of driving fluids introduced thereto to alternately thermally expand and contract to thereby cause reciprocating motion of the piston within the cylinder. Reciprocation of the piston within the cylinder alternatively pressurizes working fluid disposed within the first and the second regions of the cylinder. The pressure energy transmitted to the working fluid in the first and second regions of the cylinder is stored within a suitable energy storing arrangement to be utilized in any desired manner.

    摘要翻译： 热力发动机系统的特征在于具有设置在其中的合适工作流体的气缸，具有在气缸内沿第一和第二方向往复运动的活塞，活塞将气缸分成第一和第二加压区域。 在一个实施例中，热响应的可膨胀构件在其一个自由终端处直接可操作地连接到活塞。 在替代实施例中，热响应的可膨胀构件的自由终端通过杠杆连接间接连接到一个或多个双作用活塞缸。 热响应性可膨胀构件在其第二端处连接到用于将可膨胀构件的第二端保持在基本上静止位置的适当装置。 热响应的可膨胀构件响应于引入其中的驱动流体的温度交替地热膨胀和收缩，从而引起活塞在气缸内的往复运动。 气缸内的活塞的往复交替地加压设置在气缸的第一和第二区域内的工作流体。 在气缸的第一和第二区域中传递到工作流体的压力能量被储存在合适的储能装置中以便以任何所需的方式使用。

    Angle trisector
    4.
    发明授权
    Angle trisector 失效
    角度分析器

    公开(公告)号：US3693261A

    公开(公告)日：1972-09-26

    申请号：US3693261D

    申请日：1970-06-02

    申请人： WILLIAM M MOORE

    发明人： MOORE WILLIAM M

    IPC分类号： B43L7/12 ,  B43L9/08

    CPC分类号： B43L7/12

    摘要： Transparent plastic T-square, dual blade, and protractor devices for performing geometrical and trigonometrical measurements with particular emphasis on trisecting angles and dividing angles into a plurality of equal segments.

    摘要翻译： 用于进行几何和三角测量的透明塑料T形，双刀片和量角器装置，特别强调三分割角度并将分割角度分成多个相等的部分。

    Acoustically sealing earmuff for an infant
    7.
    发明授权
    Acoustically sealing earmuff for an infant 失效
    用于婴儿的声学密封耳罩

    公开(公告)号：US5243709A

    公开(公告)日：1993-09-14

    申请号：US754822

    申请日：1991-09-04

    申请人： Neil J. Sheehan ,  William M. Moore ,  William New, Jr.

    发明人： Neil J. Sheehan ,  William M. Moore ,  William New, Jr.

    IPC分类号： A61F11/14

    CPC分类号： A61F11/14

    摘要： A cup member defines a cavity for covering an infant's ear, and an annular member extends from an end portion of the cup member. The cup member and the annular member each comprise a first sound attenuating layer of foam material which attenuates high frequency sound and a second sound attenuating layer of a material which attenuates low frequency sound. The annular member has a surface for placing the earmuff against the infant's head. A hydrogel adhesive is disposed on the surface for bonding the earmuff to the infant's head. The hydrogel layer preferably extends along the plane defined by the surface of the annular member and into the cavity defined by the cup member for bonding the earmuff to a substantially hairless portion of the infant's head located behind the pinna. A portion of the annular member may be creased for forming a bendable tab which helps to conform the earmuff to the curvature of the infant's head behind the ear, and a slit may be formed in the cup member to prevent air pressure build-up in the event of compression of the cup member.

    摘要翻译： 杯构件限定用于覆盖婴儿的耳朵的空腔，并且环形构件从杯构件的端部延伸。 杯状构件和环形构件各自包括衰减高频声音的泡沫材料的第一声音衰减层和衰减低频声音的材料的第二声音衰减层。 环形构件具有用于将耳罩放置在婴儿头部上的表面。 水凝胶粘合剂设置在表面上用于将耳罩粘合到婴儿的头部。 水凝胶层优选地沿着由环形构件的表面限定的平面延伸并且进入由杯构件限定的空腔中，用于将耳罩粘合到位于针刺后面的婴儿头部的基本上无毛的部分。 环形构件的一部分可以被折起以形成可弯曲的突片，其有助于使耳罩与耳朵后面的婴儿头部的曲率一致，并且可以在杯构件中形成狭缝以防止在 杯形件的压缩事件。

    Double valve mechanism for controlling fluid flows
    9.
    发明授权
    Double valve mechanism for controlling fluid flows 失效
    用于控制流体流动的双阀机构

    公开(公告)号：US4178964A

    公开(公告)日：1979-12-18

    申请号：US734829

    申请日：1976-10-22

    申请人： Marvin L. Moore ,  Karen H. Moore ,  William M. Moore

    发明人： Marvin L. Moore ,  Karen H. Moore ,  William M. Moore

    IPC分类号： F16K11/065 ,  F16K11/06 ,  F16K11/20

    CPC分类号： F16K11/0655 ,  Y10T137/86815 ,  Y10T137/87684 ,  Y10T137/87981

    摘要： A substantially leak-free arrangement for isolating at least two fluid streams from each other and for conducting each fluid stream into a mixing zone is characterized in a first embodiment by a casing having substantially parallel upstream and downstream partitions, each partition being provided, for each fluid stream, with an orifice of a predetermined cross-section. Defined within the casing between the partitions is a valve chamber in which a valve plate, having a flow passage corresponding to each orifice in the partitions, is moveable from a first, closed, to a second, open, position. The valve plate in the first, closed, position prevents fluid communication between each of the orifices in the first partition and the corresponding orifices in the second partition. The orifices are arranged within the partitions so that, as the valve plate slidably moves from the closed to the open position, the orifices in the downstream partition are in fluid communication with the corresponding passages in the valve plate before those passages communicate with the orifices in the upstream partition. With the valve plate in the second, open, position, the passages in the valve plate register completely with the corresponding orifices in the first and second partitions to provide unobstructed flow paths for each fluid stream to a mixing region disposed downstream of the second partition. In a second embodiment of the invention, a first valve member and a second valve member cooperate to define a double valve arrangement for a single fluid flow, both valves being disposed upstream of a common mixing region. Both valves are operatively associated with an externally disposed, pivotally mounted actuator member. Movement of the actuator opens both the first and the second valves so as to introduce the fluid into the mixing region.

    摘要翻译： 用于将至少两个流体流彼此隔离并且用于将每个流体流引导到混合区中的基本上无泄漏的装置的特征在于第一实施例中的壳体具有基本上平行的上游和下游分隔件，每个分隔件设置用于每个 流体流，具有预定横截面的孔口。 在隔板之间的壳体内限定有阀室，其中具有对应于隔板中的每个孔口的流动通道的阀板可从第一闭合位置移动到第二打开位置。 处于第一，关闭位置的阀板防止第一分隔件中的每个孔和第二分隔件中的对应孔之间的流体连通。 所述孔布置在所述隔板内，使得当所述阀板从所述闭合位置滑动移动到所述打开位置时，所述下游分隔件中的所述孔口与所述阀板内的所述相应通道流体连通，然后所述通道与所述孔口连通 上游分区。 在阀板处于第二，打开位置时，阀板中的通道与第一和第二分隔件中的对应孔完全对齐，以将每个流体流的通畅流动路径提供到设置在第二分隔件下游的混合区域。 在本发明的第二实施例中，第一阀构件和第二阀构件协作以限定用于单个流体流的双阀装置，两个阀设置在公共混合区域的上游。 两个阀可操作地与外部设置的，枢转地安装的致动器构件相关联。 致动器的运动打开第一和第二阀门，以将流体引入混合区域。

    Delamination detector
    10.
    发明授权
    Delamination detector 失效
    分层检测仪

    公开(公告)号：US3937065A

    公开(公告)日：1976-02-10

    申请号：US369187

    申请日：1973-06-12

    申请人： Lionel J. Milberger ,  Gilbert Swift ,  William M. Moore

    发明人： Lionel J. Milberger ,  Gilbert Swift ,  William M. Moore

    IPC分类号： G01N29/04

    CPC分类号： G01N29/045 ,  G01N2291/0231 ,  G01N2291/02827 ,  G01N2291/2632

    摘要： To detect the presence of certain types of hidden flaws within a material having an exposed surface, the surface is tapped at one location to produce sonic vibrations within the material. At another location, an acoustic receiving transducer is coupled to the surface of the material being tested. A characteristic of the electrical signals produced by the transducer which is indicative of the type of flaw to be detected is utilized to denote the presence of a flaw. A mobile foorm of apparatus which detects flaws while traversing the surface of the material and which indicates the location as well as the existence of the flaws is described.

    摘要翻译： 为了检测具有暴露表面的材料中某些类型的隐藏缺陷的存在，表面在一个位置被敲击以在材料内产生声音振动。 在另一位置，声学接收传感器耦合到被测试材料的表面。 由换能器产生的指示要检测的缺陷类型的电信号的特征用于表示存在缺陷。 描述了在穿过材料的表面时检测瑕疵并且指示位置以及缺陷的存在的装置的移动式装置。