PURIFICATION OF RECOMBINANTLY PRODUCED INTERFERON
    4.
    发明申请
    PURIFICATION OF RECOMBINANTLY PRODUCED INTERFERON 审中-公开
    纯化生产的干扰素

    公开(公告)号:US20110257368A1

    公开(公告)日:2011-10-20

    申请号:US13141269

    申请日:2009-12-17

    IPC分类号: C07K1/18

    CPC分类号: C07K14/56

    摘要: The present invention provides a method for separating desired interferon isoforms from undesired interferon isoforms that involves subjecting the isoforms to anion exchange column chromatography and a biphasic elution procedure. A strong elution solution is used in the first elution phase to facilitate elution of the desired isoform from the column and a weak elution solution is used in the second phase to suppress elution of the desired isoforms.

    摘要翻译: 本发明提供了从期望的干扰素同种型分离所需干扰素同种型的方法,其包括使同种型进行阴离子交换柱色谱和双相洗脱程序。 在第一洗脱阶段使用强洗脱溶液以便于从柱中洗脱所需的同种型,并且在第二阶段使用弱洗脱溶液以抑制所需同种型的洗脱。

    Active decoupling of MRI RF transmit coils
    6.
    发明申请
    Active decoupling of MRI RF transmit coils 有权
    MRI射频发射线圈的主动去耦

    公开(公告)号:US20070273377A1

    公开(公告)日:2007-11-29

    申请号:US11418456

    申请日:2006-05-05

    IPC分类号: G01V3/00

    CPC分类号: G01R33/3415 G01R33/365

    摘要: An MRI RF transmit system uses a plurality of RF transmit coils, each being driven with separately controllable RF magnitude and phase. The magnitude and phase of each coil drive are separately and independently controlled so that the RF transmit coils act as if they are decoupled from each other. The controlled magnitude and phase values may be based on empirically derived information relating to self and mutual coupling of RF transmit coils.

    摘要翻译: MRI RF发射系统使用多个RF发射线圈,每个射频发射线圈分别由可控的RF幅度和相位驱动。 每个线圈驱动器的幅度和相位被单独和独立地控制,使得RF发射线圈的作用就好像它们彼此解耦一样。 受控幅度和相位值可以基于与RF发射线圈的自耦合和相互耦合有关的经验导出的信息。

    Method and apparatus for programming a memory array
    7.
    发明授权
    Method and apparatus for programming a memory array 有权
    用于编程存储器阵列的方法和装置

    公开(公告)号:US07212454B2

    公开(公告)日:2007-05-01

    申请号:US11158396

    申请日:2005-06-22

    IPC分类号: G11C29/00

    CPC分类号: G11C29/816 G11C17/14

    摘要: A method and apparatus for programming a memory array are disclosed. In one embodiment, after each word line is programmed, an attempt is made to detect a defect on that word line. If a defect is detected, the word line is repaired with a redundant word line. The word lines are then reprogrammed and rechecked for defects. In another embodiment, after each word line is programmed, an attempt is made to detect a defect on that word line. If a defect is detected, that word line is repaired along with a previously-programmed adjacent word line. In yet another embodiment, after each word line is programmed, an attempt is made to detect a defect on that word line and a previously-programmed adjacent word line. If a defect is detected on that word line, that word line and the previously-programmed adjacent word line are repaired with redundant word lines.

    摘要翻译: 公开了一种用于对存储器阵列进行编程的方法和装置。 在一个实施例中,在每个字线被编程之后,尝试检测该字线上的缺陷。 如果检测到缺陷,则用冗余字线修复字线。 字线然后被重新编程并重新检查缺陷。 在另一个实施例中,在每个字线被编程之后,尝试检测该字线上的缺陷。 如果检测到缺陷,则该字线与预先编程的相邻字线一起被修复。 在另一个实施例中,在每个字线被编程之后,尝试检测该字线上的缺陷和预先编程的相邻字线。 如果在该字线上检测到缺陷,则该字线和先前编程的相邻字线用冗余字线修复。

    Reconfigurable MRI-Guided Surgical Apparatus
    8.
    发明申请
    Reconfigurable MRI-Guided Surgical Apparatus 有权
    可重构MRI引导手术器械

    公开(公告)号:US20140128723A1

    公开(公告)日:2014-05-08

    申请号:US13670224

    申请日:2012-11-06

    IPC分类号: A61B5/055 A61B10/02

    摘要: Apparatus associated with improved magnetic resonance imaging (MRI) guided needle biopsy procedures (e.g., breast needle biopsy) are described. One example apparatus includes a support structure configured to support a patient in a face-down prone position where a breast of the patient is positioned in a first free hanging pre-imaging position. The example apparatus includes an immobilization structure configured to reposition the breast into an immobilized position suitable for MRI and for medical instrument access. The immobilization structure may include a biopsy plate, a pressure plate, and MRI coils. The MRI coils are configured to be repositioned from a first position associated with the free hanging pre-imaging position to a second position associated with the immobilized position to facilitate improving the signal to noise ratio associated with signal received from the breast through the MRI coils. The biopsy plate is removable without removing either of the MRI coils.

    摘要翻译: 描述了与改进的磁共振成像(MRI)引导的针活检程序(例如,乳房针活检)相关的装置。 一个示例性装置包括支撑结构,其被配置为将患者的患者置于朝向下倾斜的位置,其中患者的乳房位于第一自由悬挂的预成像位置。 示例性装置包括固定结构,其被配置为将乳房重新定位成适合于MRI和用于医疗器械进入的固定位置。 固定结构可以包括活检板,压力板和MRI线圈。 MRI线圈被配置为从与自由悬挂的预成像位置相关联的第一位置重新定位到与固定位置相关联的第二位置,以便于改进与通过MRI线圈从乳房接收的信号相关联的信噪比。 活检板是可移除的,而不去除MRI线圈之一。

    Method and system for providing a magnetic recording pole having a dual sidewall angle
    9.
    发明授权
    Method and system for providing a magnetic recording pole having a dual sidewall angle 有权
    用于提供具有双重侧壁角的磁记录极的方法和系统

    公开(公告)号:US08563146B1

    公开(公告)日:2013-10-22

    申请号:US13169710

    申请日:2011-06-27

    IPC分类号: G11B5/33

    摘要: A method for fabricating a magnetic transducer having an air-bearing surface (ABS). An underlayer having a first and second regions and a bevel connecting these regions is provided. The first region is thicker and closer to the ABS than the second region. An intermediate layer conformal with the underlayer is provided. A hard mask layer having a top surface perpendicular to the ABS is formed on the intermediate layer. Part of the hard mask and intermediate layers are removed to provide a trench. The trench has a bottom surface and sidewalls having a first angle between the bottom surface and the intermediate layer and a second angle corresponding to the hard mask layer. A pole is provided in the trench. The pole has a pole tip, a yoke distal, and a bottom bevel. At least the yoke includes sidewalls having sidewall angles corresponding to the first and second angles.

    摘要翻译: 一种制造具有空气轴承表面(ABS)的磁换能器的方法。 提供具有第一和第二区域的底层以及连接这些区域的斜面。 第一区域比第二区域更厚且更接近ABS。 提供与底层共形的中间层。 在中间层上形成具有垂直于ABS的顶表面的硬掩模层。 除去硬掩模和中间层的一部分以提供沟槽。 沟槽具有底表面和在底表面和中间层之间具有第一角度的侧壁和对应于硬掩模层的第二角度。 在沟槽中设置一个极点。 杆具有极尖,轭远端和底斜面。 至少轭包括具有对应于第一和第二角度的侧壁角的侧壁。