公开(公告)号：US10919952B2

公开(公告)日：2021-02-16

申请号：US16290859

申请日：2019-03-02

申请人： Xuechuan Wang ,  Mengdi Hou ,  Xinhua Liu ,  Chengyuan Liang ,  Ouyang Yue ,  Manhui Zheng ,  Xing Zhu ,  Qingxin Han ,  Ji Li ,  Huijie Zhang ,  Taotao Qiang

发明人： Xuechuan Wang ,  Mengdi Hou ,  Xinhua Liu ,  Chengyuan Liang ,  Ouyang Yue ,  Manhui Zheng ,  Xing Zhu ,  Qingxin Han ,  Ji Li ,  Huijie Zhang ,  Taotao Qiang

IPC分类号： C07K14/78

摘要： A method for preparing a collagen from a chromium-containing tanned leather waste is disclosed. The method includes acid dechromation, obtaining a collagen aggregate, and converting the collagen aggregate to the collagen. The method also includes a reaction in a supercritical carbon dioxide reactor.

公开(公告)号：US20190031840A1

公开(公告)日：2019-01-31

申请号：US16027193

申请日：2018-07-03

申请人： Chengyuan LIANG ,  Lei TIAN ,  Minyi JIA ,  Ying HUANG ,  Xuechuan WANG ,  Taotao QIANG ,  Longfang REN ,  Xingke JU

发明人： Chengyuan LIANG ,  Lei TIAN ,  Minyi JIA ,  Ying HUANG ,  Xuechuan WANG ,  Taotao QIANG ,  Longfang REN ,  Xingke JU

IPC分类号： C08J5/18 ,  G01N33/569 ,  C08L89/06 ,  B65D65/46

CPC分类号： C08J5/18 ,  B65D65/466 ,  C08J2389/06 ,  C08L89/06 ,  C08L2201/06 ,  C08L2201/08 ,  C08L2201/10 ,  C08L2201/14 ,  C08L2203/16 ,  C09H3/00 ,  G01N33/56911 ,  G01N2333/335 ,  G01N2333/4603

摘要： A method of preparing an aesculin sturgeon skin gelatin with antioxidant activity and Enterococcus faecalis detection ability includes: 1) mixing a sturgeon skin gelatin and distilled water in a ratio of 1:15-1:25 (w/v) at 50-70° C. and filtering to obtain a sturgeon skin gelatin solution; 2) adding aesculin and a glycerin solution to the sturgeon skin gelatin solution, stirring the resulted sturgeon skin gelatin solution at 30-50° C. for 30 minutes, and filtering; and 3) removing air bubbles from the sturgeon skin gelatin solution of step 2) under reduced pressure, placing the sturgeon skin gelatin solution on an acrylic glass, and drying the sturgeon skin gelatin solution at in a vented oven 25° C. and 45-55% relative humidity for 24 hours to obtain the aesculin sturgeon skin gelatin film.

公开(公告)号：US09758486B1

公开(公告)日：2017-09-12

申请号：US15489713

申请日：2017-04-17

申请人： Chengyuan Liang ,  Danni Tian ,  Minyi Jia ,  Xiaolin Xie ,  Dezhu Zhang ,  Weihui Ju ,  Shunjun Ding ,  Xuechuan Wang

发明人： Chengyuan Liang ,  Danni Tian ,  Minyi Jia ,  Xiaolin Xie ,  Dezhu Zhang ,  Weihui Ju ,  Shunjun Ding ,  Xuechuan Wang

IPC分类号： C07D231/36 ,  C07D231/22 ,  C07D231/26

CPC分类号： C07D231/36 ,  C07D231/22 ,  C07D231/26

摘要： A compound with antitumor activities represented by formula I: In formula I, R1 is alkyl, alkoxy, or ethenyl; and R2 is alkyl, alkoxy, or halogen.

公开(公告)号：US20220023507A1

公开(公告)日：2022-01-27

申请号：US17203689

申请日：2021-03-16

申请人： Xuechuan WANG ,  Manhui ZHENG ,  Xinhua LIU ,  Ouyang YUE ,  Mengdi HOU ,  Youyou WANG

发明人： Xuechuan WANG ,  Manhui ZHENG ,  Xinhua LIU ,  Ouyang YUE ,  Mengdi HOU ,  Youyou WANG

IPC分类号： A61L27/60 ,  A61L27/26 ,  A61L27/08 ,  B29B7/90 ,  B29C45/00

摘要： A method for preparing a conductive biomimetic skin scaffold material with self-repairing function includes the following steps: adding 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride to a homogeneous dispersion of acidified carbon nanotubes, poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS), and gelatin to cross-link to obtain a conductive composite colloid; and injecting the conductive composite colloid into a mold, aging at −4-4° C. for 12-24 hours, and then soaking in a phosphate-buffered saline (PBS) solution with a pH of 7.0-7.4 for 12-24 hours to obtain the conductive biomimetic skin scaffold material.

公开(公告)号：US10815348B2

公开(公告)日：2020-10-27

申请号：US16027193

申请日：2018-07-03

申请人： Xuechuan Wang ,  Ouyang Yue ,  Xinhua Liu ,  Taotao Qiang ,  Longfang Ren ,  Lei Tian ,  Minyi Jia ,  Xingke Ju ,  Chengyuan Liang

发明人： Xuechuan Wang ,  Ouyang Yue ,  Xinhua Liu ,  Taotao Qiang ,  Longfang Ren ,  Lei Tian ,  Minyi Jia ,  Xingke Ju ,  Chengyuan Liang

IPC分类号： C09H3/00 ,  C08J5/18 ,  B65D65/46 ,  C08L89/06 ,  G01N33/569

摘要： A method of preparing an aesculin sturgeon skin gelatin with antioxidant activity and Enterococcus faecalis detection ability includes: 1) mixing a sturgeon skin gelatin and distilled water in a ratio of 1:15-1:25 (w/v) at 50-70° C. and filtering to obtain a sturgeon skin gelatin solution; 2) adding aesculin and a glycerin solution to the sturgeon skin gelatin solution, stirring the resulted sturgeon skin gelatin solution at 30-50° C. for 30 minutes, and filtering; and 3) removing air bubbles from the sturgeon skin gelatin solution of step 2) under reduced pressure, placing the sturgeon skin gelatin solution on an acrylic glass, and drying the sturgeon skin gelatin solution at in a vented oven 25° C. and 45-55% relative humidity for 24 hours to obtain the aesculin sturgeon skin gelatin film.

公开(公告)号：US10233183B1

公开(公告)日：2019-03-19

申请号：US16043085

申请日：2018-07-23

申请人： Chengyuan Liang ,  Lei Tian ,  Yonghong Tang ,  Minghui Chang ,  Kaiqi Shi ,  Xingke Ju ,  Yuzhi Liu ,  Lili Wen ,  Han Li ,  Xuechuan Wang

发明人： Chengyuan Liang ,  Lei Tian ,  Yonghong Tang ,  Minghui Chang ,  Kaiqi Shi ,  Xingke Ju ,  Yuzhi Liu ,  Lili Wen ,  Han Li ,  Xuechuan Wang

IPC分类号： C07D471/22

摘要： A compound having the following formula I: In formula I, R1 and R2 are independently H, alkyl, alkoxy, and halogen. A method of preparing the compound of formula I is also disclosed.

公开(公告)号：US11511018B2

公开(公告)日：2022-11-29

申请号：US17203689

申请日：2021-03-16

申请人： Xuechuan Wang ,  Manhui Zheng ,  Xinhua Liu ,  Ouyang Yue ,  Mengdi Hou ,  Youyou Wang

发明人： Xuechuan Wang ,  Manhui Zheng ,  Xinhua Liu ,  Ouyang Yue ,  Mengdi Hou ,  Youyou Wang

IPC分类号： A61L27/60 ,  A61L27/26 ,  A61L27/08 ,  B29B7/90 ,  B29C45/00 ,  B29K507/04 ,  B29L31/00 ,  B29K105/16

摘要： A method for preparing a conductive biomimetic skin scaffold material with self-repairing function includes the following steps: adding 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride to a homogeneous dispersion of acidified carbon nanotubes, poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS), and gelatin to cross-link to obtain a conductive composite colloid; and injecting the conductive composite colloid into a mold, aging at −4-4° C. for 12-24 hours, and then soaking in a phosphate-buffered saline (PBS) solution with a pH of 7.0-7.4 for 12-24 hours to obtain the conductive biomimetic skin scaffold material.

公开(公告)号：US20190309051A1

公开(公告)日：2019-10-10

申请号：US16290859

申请日：2019-03-02

申请人： Xuechuan WANG ,  Mengdi HOU ,  Xinhua LIU ,  Chengyuan LIANG ,  Ouyang YUE ,  Manhui ZHENG ,  Xing ZHU ,  Qingxin HAN ,  Ji LI ,  Huijie ZHANG ,  Taotao QIANG

发明人： Xuechuan WANG ,  Mengdi HOU ,  Xinhua LIU ,  Chengyuan LIANG ,  Ouyang YUE ,  Manhui ZHENG ,  Xing ZHU ,  Qingxin HAN ,  Ji LI ,  Huijie ZHANG ,  Taotao QIANG

IPC分类号： C07K14/78

摘要： A method for preparing a collagen from a chromium-containing tanned leather waste is disclosed. The method includes acid dechromation, obtaining a collagen aggregate, and converting the collagen aggregate to the collagen. The method also includes a reaction in a supercritical carbon dioxide reactor.

公开(公告)号：US20180094167A1

公开(公告)日：2018-04-05

申请号：US15605985

申请日：2017-05-26

申请人： Chengyuan LIANG ,  Danni TIAN ,  Minyi JIA ,  Shunjun DING ,  Xuechuan WANG ,  Han LI ,  Wei LIU

发明人： Chengyuan LIANG ,  Danni TIAN ,  Minyi JIA ,  Shunjun DING ,  Xuechuan WANG ,  Han LI ,  Wei LIU

IPC分类号： C09H3/02 ,  B05D3/00 ,  B05D1/18 ,  B65D65/46

CPC分类号： C09H3/02 ,  B05D1/18 ,  B05D3/007 ,  B65D65/463

摘要： A method of preparing a sturgeon skin gelatin with antioxidant activity includes: 1) soaking sturgeon skin in water, and sonicating the sturgeon skin; 2) cutting the sturgeon skin, soaking the sturgeon skin in a NaOH solution, and soaking the sturgeon skin in an HCl solution; 3) washing the sturgeon skin of step 2) to neutral, placing the sturgeon skin in an extraction solution for extracting sturgeon skin protein; and 4) obtaining the sturgeon skin gelatin. A method of preparing a sturgeon skin gelatin film includes: 1) dissolving sturgeon skin gelatin in water to obtain a sturgeon skin gelatin solution; 2) adding glycerine to the sturgeon skin gelatin solution; and 3) obtaining the sturgeon skin gelatin film.

公开(公告)号：US20220213318A1

公开(公告)日：2022-07-07

申请号：US17498181

申请日：2021-10-11

申请人： Na XU ,  Yanmei XING ,  Xuechuan WANG

发明人： Na XU ,  Yanmei XING ,  Xuechuan WANG

IPC分类号： C08L77/00 ,  C08J3/24 ,  C08L89/06 ,  D06M15/15 ,  D06M13/127 ,  D06M13/507 ,  D06M10/00

摘要： A method of preparing a vinyl collagen microsphere polyamide fiber composite material includes the following steps: step 1: modifying a collagen with methacrylic anhydride to obtain a vinyl collagen, then emulsifying and cross-linking the vinyl collagen to obtain vinyl collagen microspheres; step 2: treating a polyamide fiber substrate with formaldehyde to obtain a hydroxylated polyamide fiber substrate, treating the hydroxylated polyamide fiber with (3-mercaptopropyl)trimethoxysilane (MPS) to obtain a sulfhydrylated polyamide fiber substrate; and step 3: modifying the sulfhydrylated polyamide fiber substrate with the vinyl collagen microspheres to obtain the vinyl collagen microsphere polyamide fiber composite material.